TIE Kinetix (Germany)

Abstract STEM fields rely heavily on innovation to solve complex problems and create new technologies. Entrepreneurship education nurtures students' ability to think creatively, identify opportunities, and develop innovative solutions, making them better equipped to tackle the challenges they will encounter in their engineering and STEM careers. It prepares them for future success by fostering innovation, building essential skills, promoting financial literacy, encouraging leadership, and addressing socioeconomic disparities. The success of entrepreneurship in education has predominantly been examined through economic lenses such as increases in earnings or jobs created at the higher education level. In this paper, we report on the remarkable success of the TYE program and it's empowerment of high school students through extracurricular entrepreneurship education outside the school system. The TYE (TiE Young Entrepreneurs) program was set up in 2005 in Boston and scaled to 30 different locales globally. Our paper will focus on how students in the age group of 16-18 yrs perceived this program and the reported positive outcomes it had for their future education and career prospects. The TYE program is administered over eight months duration, through a combination of practical training, curriculum, and mentoring, by practitioners who are seasoned entrepreneurs. The program gives high school students the opportunity to form teams, build a real start-up, deliver a Pitch Deck with a Business Model Canvas and Business Plan Summary, as well as the opportunity to win seed funding for their startup. In our paper, we explore the impact of the TYE program, measured through the SEEQ tool (Student Evaluation of Educational Quality). In addition, we report on case studies of success stories, and develop a descriptive analysis of our findings. Entrepreneurship education provides high school students with a diverse set of transferable skills that are essential for success in STEM fields. These include team work, problem-solving, confidence, collaboration, and technical skills such as financial literacy, communication, and leadership. Engineering projects require funding and budget management skills, and learning financial literacy, budgeting, fund raising, and investing, provide essential skills for project management. Entrepreneurship education empowers high school students to take initiative, pursue their ideas, and become leaders in their chosen fields. This mindset is particularly valuable in engineering and STEM professions, where individuals often need to take charge of projects, lead teams, and drive innovation. In conclusion, the paper demonstrates that with the TYE supported entrepreneurial education and training, students report outcomes including their being influenced to pursue a career in STEM and/or start their own company. In addition, the companies the students sought to start were focused on value creation for other people. With engagement with a program such as TYE, high school students choosing the engineering field in college can apply their technical knowledge to develop practical solutions to societal challenges, create prototypes, and test their ideas in real-world settings, thus preparing them for careers where they can make a tangible impact, before they get to college itself.

Mediante una aproximación teórica hacia una historia integrada o articulada, sustentada en la metodología del Continuum cultural (Espinoza et al. 2023), se trazan las múltiples formas en que la Pirámide E del complejo arqueológico Mateo Salado (Lima, Perú) ha sido usada y por lo tanto reinterpretada y monumentalizada por diversos grupos humanos que han coexistido o se han sucedido en el tiempo. Se muestra así que un monumento es un espacio multívoco y en cambio constante, y no nada más la manifestación pública y representativa de una élite en el poder. Sin embargo, para prever que no haya un solo discurso que domine, el monumento debe posibilitar espacios de encuentro y dialogo democrático, como es el evento “Encuentro por la fraternidad y la tolerancia religiosa” que se celebra en Mateo Salado desde el 2018.

El objetivo principal de la presente investigación reside en identificar las prácticas editoriales relacionadas con la gestión del tiempo en las revistas científicas españolas de Comunicación y conocer si existe homogeneidad en la gestión del tiempo, detectar revistas más ágiles, conocer si existen diferencias entre publicaciones generales y monográficos específicos e identificar praxis que agilicen los procesos de publicación. Para ello, se ha trabajado en una metodología de corte exploratorio, centrada en el análisis de contenido. La muestra analiza los 1581 artículos publicados en 2021 por las 62 revistas científicas de Comunicación del Índice Dialnet de Revistas 2020, diferenciando entre aquellos que han sido publicados en la sección “Miscelánea” de aquellos que aparecen publicados en “Monográfico”, con la finalidad de centrar la atención en los plazos transcurridos desde que las revistas reciben los artículos hasta que finalmente son publicados. Los resultados evidencian escasa homogeneidad en la política relativa a la información sobre fechas y constata promedios de más de seis meses en la duración del proceso, siendo más ágiles los procesos de la publicación en “Monográfico”. El punto fuerte de este trabajo se encuentra en la manifestación de la necesidad de trabajar en políticas comunes que permitan, por una parte, agilizar los procesos de publicación y, en segundo lugar, acelerar la visibilización de los resultados de investigación, con el fin de beneficiar a la comunidad científica y la sociedad.

摘要： 基于MSC.Marc通用有限元软件平台，开发了同时考虑材料非线性、几何非线性和边界非线性的热-弹-塑性有限元方法用于模拟1 500 MPa级超高强钢薄板接头的焊接变形；同时也开发了基于固有应变理论的弹性有限元方法来计算大型复杂结构的焊接变形。首先，以1 500 MPa级超高强钢薄板对接接头为研究对象，分别采用热-弹-塑性有限元方法和固有应变法模拟了焊接变形，并与试验结果进行比较，计算误差均小于15%。随后，以1 500 MPa级超高强钢大型复杂薄壁结构为研究对象，采用热-弹-塑性有限元法计算薄壁结构中典型焊接接头在自由和强制拘束条件下的固有变形，考察拘束条件对焊接接头变形的影响。最后，基于固有应变理论计算了超高强钢复杂薄壁结构的整体焊接变形，并研究了强制拘束对薄壁结构焊接变形的影响。数值模拟结果表明，采用外部强制拘束可以在一定程度上减小薄壁结构的总体变形。

Objective: To determine the prevalence of precancerous lesions in the Lekoumou and Niari departments. Patients and Methods: this was a descriptive and cross-sectional study over a period of 7 months from January to July 2020 in the department of of lekoumou, The analyzes were made in the Laboratory of Medical and Morphological Analysis of the General Hospital of Loandjili. Our study involved a population of 100 women ranging in age from 16 to 73 years old. All of these women voluntarily benefited from a cervico-uterine sample. The cytological study was based on the international classification of BETHESDA 2001, taking into account the quality of the sample and the cell morphology. The variables studied were: age, marital status, level of education, cytology. Bivariate analyze was done between age and cytology. All the results of this study were statistically analyzed from the Chi-square test or Fisher's exact test using Epi-InfoTM software version 7.1.1.14, USA (http:// www.epiinfo.com). Results: The mean age of the patients was 34.6 ± 11.9 with extremes ranging from 16 to 73 years. The most represented age groups were 20-29 years old (31%) and 30-39 years old (29%). Our study population was predominantly college, accounting for 53% of cases. The proportion of uneducated women represented 11% of our study population. Almost 3⁄4 of our study population were married women (74%). Singles represented only 22% of the study population. More than half of our study population, 58%, had normal cytology. Benign and reactive cell changes were diagnosed in 20% of cases. Low-grade and high-grade precancerous lesions were observed in 8% and 12% of cases, respectively. High-grade intraepithelial lesions were more represented in patients aged between 27 and 36 years 50%, high-grade lesions represented in 47% of cases. there were no statistically significant result between age and cytology. Conclusion: prevalence of precancerous lesions is relatively high It is well known that intraepithelial neoplasia precedes invasive carcinoma after a period of about 10 years. knowledge of these precancerous lesions is necessary for optimal prevention of cervical cancer.

El presente artículo pretende realizar una aproximación desde el análisis textual a los juegos Until Dawn y Man of Medan (Supermassive Games, 2015 y 2019), partiendo de las diferencias entre tiempo existencial y el tiempo videolúdico. Para ello, se analizarán ambos juegos en torno a los siguientes factores: en primer lugar, se realizará un breve análisis de lo que implica morir en el videojuego en relación con las teorías propias de la clausura literaria – el llamado “modo del relato clásico”. En segundo lugar, se procederá al análisis propio de los juegos, partiendo de dos directrices: la naturaleza del mal –en sus dimensiones humana (esencialista) y sobrenatural (literaria)-, y la posición que ambos juegos toman sobre la muerte –en cuanto a mecánicas y recursos cognitivos, pero también en cuanto a su dimensión simbólica. Finalmente, se ofrecen las conclusiones y se plantean algunas sugerencias con respecto al futuro de la investigación

Magíster en Estudios Latinoamericanos

El siguiente artículo analiza la aplicación de Jus Post Bellum, un concepto derivado de la teoría de la Guerra Justa de Michael Walzer. En primer lugar, se concede una definición de la teoría de la guerra Justa a partir de los enunciados de Williams y Caldwell. Luego, se explica Jus Post Bellum, esto incluye obligaciones que tienen los Estados al momento de intervenir. A continuación, se destacan varios casos en los cuales, Estados Unidos se adhirió a los principios de Jus Post Bellum. Y, después, situaciones en las cuales no lo hizo. Finalmente se utilizan estos ejemplos para explicar cómo ha cambiado la moralidad de los estados a través del tiempo.

The objective of this study was to train the visuospatial and semantic working memory of a sample of Colombian older adults through the design of a serious game. The sample was composed of 20 older adults whose ages ranged from 50 to 77 years and showed signs of normal ageing. The sample belonged to the Edad de Oro group from the Universidad de Ibagué in Colombia. Participation in this study was voluntary, and the socio-demographic data and Mini-Mental state examination questionnaires were administered. The video game’s creative process was developed over six months by a team made up of psychologists and systems engineers. The video game was created using 2D Construct3 game editor, and the use of JavaScript programming language and an advanced knowledge of HTML were required. Before training, two pilot sessions were carried out to adjust the video game structure. After that, the procedure was applied to the sample for 20 sessions. The time spent and errors made in the video game’s five levels were registered. The results show values of significant effect size. In conclusion, the Latin American samples help corroborate the central training hypothesis. Training through video games leads to improved visuospatial and semantic working memory performance.

Paired associative stimulation is a relatively new non-invasive brain stimulation technique that combines transcranial magnetic stimulation and peripheral nerve stimulation. The effects of paired associative stimulation on the excitability of the cerebral cortex can vary according to the time interval between the transcranial magnetic stimulation and peripheral nerve stimulation. We established a model of cerebral ischemia in rats via transient middle cerebral artery occlusion. We administered paired associative stimulation with a frequency of 0.05 Hz 90 times over 4 weeks. We then evaluated spatial learning and memory using the Morris water maze. Changes in the cerebral ultra-structure and synaptic plasticity were assessed via transmission electron microscopy and a 64-channel multi-electrode array. We measured mRNA and protein expression levels of brain-derived neurotrophic factor and N-methyl-D-aspartate receptor 1 in the hippocampus using a real-time polymerase chain reaction and western blot assay. Paired associative stimulation treatment significantly improved learning and memory in rats subjected to cerebral ischemia. The ultra-structures of synapses in the CA1 area of the hippocampus in rats subjected to cerebral ischemia were restored by paired associative stimulation. Long-term potentiation at synapses in the CA3 and CA1 regions of the hippocampus was enhanced as well. The protein and mRNA expression of brain-derived neurotrophic factor and N-methyl-D-aspartate receptor 1 increased after paired associative stimulation treatment. These data indicate that paired associative stimulation can protect cognition after cerebral ischemia. The observed effect may be mediated by increases in the mRNA and protein expression of brain-derived neurotrophic factor and N-methyl-D-aspartate receptor 1, and by enhanced synaptic plasticity in the CA1 area of the hippocampus. The animal experiments were approved by the Animal Ethics Committee of Tongji Medical College, Huazhong University of Science & Technology, China (approval No. TJ-A20151102) on July 11, 2015.