Tbilisi Humanitarian Teaching University

Background/Purpose: Coronavirus disease 2019 (COVID-19) has become the cause of a global health crisis during the pandemic. This research aimed to study the impact of symptomatic COVID-19 on children’s oral health indices and salivary microbiome composition during the post-COVID-19 period. Methods: An observational, cross-sectional study was conducted in Tbilisi (Georgia) among children aged 7–12 years. A total of 421 children included in the study had a history of laboratory-confirmed COVID-19 within one year of exposure. No participants met the criteria for comorbid conditions or for PCC. A stratified simple random selection of schools and among selected clusters was used. The selected children were divided into two groups: the exposed group, who were patients with a history of symptomatic COVID-19, and the control group, who were patients with a history of asymptomatic COVID-19. The data were collected from August 2022 to December 2023. Oral screening, microbiological examination of saliva, and administration of questionnaires were also performed. Logistic regression was used to calculate ORs with 95% confidence intervals. The statistical processing of the data was performed with SPSS 23.0. This study was approved by the Biomedical Research Ethical Council of the University of Georgia (UGREC–04–22/9 March 2022). Results: Statistically significant differences in the means of the oral health indicators between the studied groups were detected (exposed: DMFT + deft = 5.9; MGI = 0.92; S-OHI = 1.9; control: DMFT + deft = 3.8; MGI = 0.56; S-OHI = 1.4). According to the logistic regression, symptomatic COVID-19 had a significant effect on the following oral health indicators: DMFT + deft (OR = 1.26; 95% CI = 1.14–1.39), MGI (OR = 2.31; 95% CI = 1.50–3.55), and S-OHI (OR = 3.43; 95% CI = 2.03–5.76). The effect of symptomatic COVID-19 on the frequency of eradication of the studied microbiome was also significant (OR = 2.12; 95% CI = 1.23–3.63). Conclusions: A close association was established between symptomatic COVID-19 and microbiome changes in the oral saliva of children, as well as between oral health indicators and symptomatic COVID-19. Considering the research results, it is assumed that a symptomatic course of COVID-19 may be an additional risk factor associated with poor oral health in the pediatric population in the post-COVID-19 period.

Abstract Background The aim of the study is to evaluate the diagnostic accuracy of intraoral mobile photography to assess caries intensity (DMFT/deft), simplified oral hygiene index (S-OHI) and modified gingival index (MGI). Methods Children aged 7-12 were included in the study. The clinical doctor evaluated the oral health indicators by visual examination: DMFT, deft, S-OHI, MGI were calculated. Dental students independently captured photos with a mobile phone (iPhone-11) in 8 predetermined projections. Dental images were kept in coded folders for research anonymity. Another professional calculated index based on the photos. Variables were used with binary values (DMFT/deft = 0/≥1; MGI=0/≥1; S-OHI≤1.2/>1.2). Sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV) of dental photography were evaluated and Cohen’s Kappa was calculated to measure the level of agreement between two independent observers. Results 2864 photographs were evaluated for 358 participants. The sensitivity and specificity of intraoral mobile photography for DMFT index is 95.8 (95% CI: 93.4-98.3) and 89.2 (95% CI: 83-95.5); For deft index: 100.0 (95% CI: 100-100) and 88.6 (95% CI: 79.3-98); For MGI: 89.7 (95% CI: 85.8-93.5) and 91.4 (95% CI: 86.3-96.5); For S-OHI: 77.6 (95% CI: 67.6-87.6) and 93.8 (95% CI: 91-96.6); The PPV value for DMFT, deft, MGI and S-OHI is 96.2; 97.7; 95.6 and 74.3 and the NPV value is 88.3; 100.0; 80.9 and 94.8 respectively. It was achieved substantial and perfect agreement between two independent raters: For DMFT, deft, MGI, S-OHI indices Cohen’s Kappa =0.85; 0.93; 0.78; 0.70 correspondingly. Conclusions Intraoral mobile photography, if applied within appropriate guidelines is reliable for assessing caries intensity, simplified hygiene index and modified gingival index as well as visual screening and may become a priority for dental public health. The involvement of dental students in studies of similar design is appropriate. Key messages • Intraoral mobile photography can be used for oral health screening in children. • The involvement of dental program students in screening studies conducted with intraoral mobile photography is appropriate.

Abstract Background Mobile dental photography is increasing in relevance in the diagnosis of oral diseases. This study aimed to evaluate the diagnostic accuracy of intraoral mobile photography in assessing caries intensity (decayed, missing/extracted, filled teeth), simplified oral hygiene index, and modified gingival index. Methods This study included 358 children of 7–12 years of age. A clinician evaluated decayed, missing/extracted, filled teeth; simplified oral hygiene; and modified gingival indices by visual examination. Simultaneously, dental students recorded intraoral photographs with a mobile phone in eight predetermined projections. Another oral professional calculated indices based on the photographs. Sensitivity, specificity, and positive and negative predictive values of dental photography were evaluated, and Cohen's kappa was calculated. Results A total of 2864 photographs were evaluated in this study. The sensitivity and specificity of mobile photography for decayed, missing, filled teeth; decayed, extracted, filled teeth; simplified oral hygiene, and modified gingival indices were 95.8 (95% confidence interval: 93.4–98.3) and 89.2 (83–95.5); 100.0 (100–100) and 88.6 (79.3–98); 89.7 (85.8–93.5) and 91.4 (86.3–96.5); and 77.6 (67.6–87.6) and 93.8 (91–96.6), respectively; positive predictive values were 96.2, 97.7, 95.6, and 74.3; negative predictive values 88.3, 100.0, 80.9, and 94.8; and Cohen’s Kappa values were 0.848, 0.928, 0.784, and 0.702, respectively. Conclusions Intraoral mobile photography, based on appropriate guidelines, is reliable for assessing decayed, missing/extracted, filled teeth; simplified oral hygiene; and modified gingival indices in children and could be a useful tool in dental public health, supporting the involvement of dental students in similar research studies.