Tianjin Plastics Research Institute

Remote video-based ML may improve clinical practice and future research, particularly by combining advanced technologies such as facial recognition. It is a potential tool for diagnosing ASD in children. • The incidence of pediatric ASD has increased in recent years. • ML based on remote video has shown ideal early diagnostic value. • The first systematic review and meta-analysis evaluating the diagnostic performance of remote video-based ML for ASD. • Home video-based ML is a valuable diagnostic tool for the early diagnosis of ASD. • Remote video-based ML is convenient and simple to utilize.

Cathepsin G (CTSG) plays an important role in the regulation of immune processes. Accumulated studies show that CTSG is involved in the onset and development of type 1 diabetes mellitus (T1DM). As the genetic background of T1DM varies widely among populations, we aimed to study the relationship between genetic polymorphisms in CTSG and T1DM susceptibility in Chinese populations. A total of 141 patients with T1DM and 200 healthy controls were enrolled in the study. Serum CTSG expression was detected using enzyme-linked immunosorbent assay (ELISA). Genotyping of two selected single nucleotide polymorphisms (SNPs) (rs2236742 and rs2070697) of CTSG was performed using PCR and Sanger sequencing. CTSG expression in patients with T1DM was significantly higher than in the control group. Alleles C and T of CTSG SNP rs2236742 were increased in T1DM. No significant associations were found for the SNP rs2070697. Our results indicate that the CTSG rs2236742 allele (C/T) is associated with T1DM in Chinese children and may serve as a new biomarker for predicting T1DM susceptibility.

The processing of oligomers and oligomer-filled compounds into end articles is based on the ability of these materials to flow during a definite time, which may be called the induction period t*. For t > t* their viscosities increase rapidly and they lose this ability. The parameter t* and its temperature dependence are the main technological properties of curing compounds and the determination of t* has a general significance for different methods of processing (and applying) various polymers.

The question is treated whether in the study of linear visco-elastic behavior of a material change of temperature is completely equivalent to a shift of the logarithmic time scale or not. If it is, the material is termed ``thermo-rheologically simple'' (class A). It is shown that, by plotting the results of a similar rheological experiment (for instance, a creep experiment) performed at different temperatures and comparing the curves obtained, one can decide whether the materials considered belongs to class A or not, by seeing whether the curves can be made to fit by shifting them along the axis of logarithmic time. Once the material has been decided to behave thermo-rheologically simple, one can plot the function describing the time-shift as function of the temperature. Some examples of thermo-rheologically simple materials are quoted from the literature. The micro-rheological conditions for thermo-rheologically simple behavior are discussed. It turns out that this behavior implies that in similar deformations at different temperatures always the same sequence of molecular events follows, whereas in materials not belonging to class A, not only the speed, but also the sequence of molecular processes changes when the temperature of the experiment changes. This implies, that materials of class A cannot from a heat treatment assume a special structure which could not be obtained by one temperature, whereas for materials of class B a heat treatment can indeed result in a special structure. It is reasonable to expect that thermo-rheologically simple materials will be found only among polymers containing no crystallites and no pronounced polar groups.

Abstract The syntheses of three linear condensation products of ε‐aminocaproic acid of a low degree of condensation, H[NH(CH2)5CO]xOH x = 3, 4 and 5, are described. The purification of these compounds has been accomplished by means of chromatographic adsorption.

Abstract The following substances, not yet described in the literature, were prepared:N‐tert‐butyl methacrylamide, m.p. 59° C, b.p. 111°° C/42 mm.tert‐butyl methacrylate, b.p. 136° C, fr.p. −48° C.N‐methacrylyl‐benzenesulphonamide, m.p. 128–129° C.N‐methacrylyl‐p‐toluenesulphonamide, m.p. 153–154° C.An improved method of preparation for methacrylic acid and methacrylyl chloride is described.Densities and refractions of several of these compounds are given.Some of these compounds have been polymerised and the solubility of the polymers in various solvents has been determined.