Universidad Regiomontana

The present study analyzes the reuse of basic emergency shelter units, intending to adapt them as temporary shelters for deported migrants on the border between México and the United States. In the current geopolitical context, characterized by restrictive immigration policies and increased mass deportations, it is essential to provide efficient and sustainable housing solutions. The methodology used is based on a typological, functional, and structural analysis of different models of temporary shelters, evaluating their viability, adaptability, durability, thermal efficiency, and sustainability are considered, as well as integrating design strategies that improve habitability conditions. The results show that existing basic units can serve as shelters with minimal modifications, incorporating renewable energy systems, thermal insulation, and optimized space distribution. The research highlights the role of architecture as a key tool in responding to migration crises, promoting innovative and resilient solutions, and addressing the growing need for humanitarian infrastructure on the border.

The worldwide prevalence of chronic kidney disease (CKD) is estimated to exceed 700 million persons, with the incidence steadily increasing due to factors such as an aging population and the growing prevalence of chronic diseases such as diabetes and hypertension. Cardiovascular disease is the primary cause of illness and mortality in persons with nephropathy. Effectively treating nephropathy and cardiovascular risk in individuals with kidney disease is a major challenge in clinical practice. Every patient requires a comprehensive assessment and tailored therapy. In order to reduce the likelihood of cardiovascular events in patients with nephropathy, it is necessary to avoid and rapidly address cardiovascular risk factors. In order to enhance the overall well-being and longevity of individuals with kidney disease, it is essential to identify and address any cardiovascular issues.

Mechatronics and Robotics (MaR) have recently gained importance in product development and manufacturing settings and applications. Therefore, the Center for Space Emerging Technologies (C-SET) has managed an international multi-disciplinary study to present, historically, the first Latin American general review of industrial, collaborative, and mobile robotics, with the support of North American and European researchers and institutions. The methodology is developed by considering literature extracted from Scopus, Web of Science, and Aerospace Research Central and adding reports written by companies and government organizations. This describes the state-of-the-art of MaR until the year 2023 in the 3 Sub-Regions: North America, Central America, and South America, having achieved important results related to the academy, industry, government, and entrepreneurship; thus, the statistics shown in this manuscript are unique. Also, this article explores the potential for further work and advantages described by robotic companies such as ABB, KUKA, and Mecademic and the use of the Robot Operating System (ROS) in order to promote research, development, and innovation. In addition, the integration with industry 4.0 and digital manufacturing, architecture and construction, aerospace, smart agriculture, artificial intelligence, and computational social science (human-robot interaction) is analyzed to show the promising features of these growing tech areas, considering the improvements to increase production, manufacturing, and education in the Region. Finally, regarding the information presented, Latin America is considered an important location for investments to increase production and product development, taking into account the further proposal for the creation of the LATAM Consortium for Advanced Robotics and Mechatronics, which could support and work on roboethics and education/R+D+I law and regulations in the Region. Doi: 10.28991/ESJ-2023-07-04-025 Full Text: PDF

<div>Abstract<p>Pancreatic adenocarcinoma (PDAC) epitomizes a deadly cancer driven by abnormal KRAS signaling. Here, we show that the eIF4A RNA helicase is required for translation of key KRAS signaling molecules and that pharmacological inhibition of eIF4A has single-agent activity against murine and human PDAC models at safe dose levels. EIF4A was uniquely required for the translation of mRNAs with long and highly structured 5′ untranslated regions, including those with multiple G-quadruplex elements. Computational analyses identified these features in mRNAs encoding KRAS and key downstream molecules. Transcriptome-scale ribosome footprinting accurately identified eIF4A-dependent mRNAs in PDAC, including critical KRAS signaling molecules such as PI3K, RALA, RAC2, MET, MYC, and YAP1. These findings contrast with a recent study that relied on an older method, polysome fractionation, and implicated redox-related genes as eIF4A clients. Together, our findings highlight the power of ribosome footprinting in conjunction with deep RNA sequencing in accurately decoding translational control mechanisms and define the therapeutic mechanism of eIF4A inhibitors in PDAC.</p>Significance:<p>These findings document the coordinate, eIF4A-dependent translation of RAS-related oncogenic signaling molecules and demonstrate therapeutic efficacy of eIF4A blockade in pancreatic adenocarcinoma.</p></div>

fractura conminuta de huesos nasales, fractura nasal inestable, trauma nasal, reducción cerrada de fractura, férula nasal externa.

Las mujeres trans enfrentan un riesgo desproporcionado de adquirir el VIH. Este estudio analiza cualitativamente el riesgo del VIH en mujeres trans mexicanas desde el género como estructura social. Se trata de un estudio cualitativo realizado en el noreste de México. Se hicieron 15 entrevistas a mujeres trans de entre 22 y 69 años y se realizó un análisis temático. El análisis de las entrevistas reveló tres categorías temáticas: construcciones sociales del VIH y estigma, el género y el VIH en las relaciones interpersonales, y el género y el VIH en las instituciones y la política. Los resultados muestran que las construcciones sociales del VIH se tejen en el colectivo, a partir de la interacción con otras mujeres trans. El VIH es un fenómeno atravesado por la temporalidad sociohistórica y, en ese sentido, se generan las percepciones de riesgo frente a él. El género como estructura de opresión se vincula con las experiencias de estigma y discriminación, así como la búsqueda de la legitimación del género a través de las relaciones con parejas sexuales. Las instituciones y la política pública se relacionan con el acceso a los servicios de salud, además se identifican y analizan las barreras institucionales, personales y colectivas a partir de la identidad de género. La política sostiene y refuerza la marginalización de las mujeres trans impactando en el riesgo del VIH. Los resultados muestran que el riesgo del VIH es un fenómeno multicausal basado en el género como estructura de opresión con implicaciones sistémicas.

Los medios de comunicación son un agente socializador de procesos de redefinición identitaria. Aquí se muestra cómo cierto contenido de telenovelas es resignificado y valorado por universitarios indígenas, así como su identificación con él. Se organizaron grupos de discusión cuyos resultados sugieren que el género determina cómo el contenido de telenovelas es interiorizado y su vinculación con la conciencia del ser indígena.

The aim of this study was to characterize and compare the morphological and histomorphometric characteristics of the pectoral fascia, fascia lata and ventral rectus sheath. Twenty cadaveric samples of these fascias were analyzed and stained with hematoxylin and eosin, orcein, Van Gieson, Masson's trichrome and Verhoeff¨s stain (1200 slides in total). Morphological evaluation, semiquantitative, morphometric and microdensitometric analysis of elastic fibers present in each of the tissues and a morphometrical analysis of tissue thickness were performed. The mean value of the pectoral fascia thickness was 612±68.13 μm; 84±246 μm for the fascia lata and 584±92 μm for the ventral rectus sheath. The area occupied by the elastic fibers in the pectoral fascia was 12.24±5.84%; 6,54±3.85% for the fascia lata and 11.11±5.26% for the ventral rectus sheath. There were no statistically significant differences when comparing the mean values between the pectoral fascia and the ventral rectus sheath (p=0.07). There were statistically significant differences when comparing the fascia lata to the pectoral fascia and the ventral rectus sheath (p≤0.001). This study reports other morphological characteristics not described in previous histological studies of the analyzed tissues. The results of the morphometric and densitometric analysis in this study reveal that the fascia lata has the fewest elastic fibers of all the tissues analyzed, and the pectoral fascia has the most. These results will be useful for the beginning of a morphological information bank of human fascias.

Objective: To investigate the class, type, position, diagnosis and most common procedures used in the surgical removal of third molars, and evaluate the sex and age distribution in a representative sample of Mexican patients. Study Design: A retrospective descriptive study was made covering the period 1993-2008 in relation to 9148 extracted third molars in 3206 patients treated in the Dental School of Salle Bajío University, A.C. (Mexico). Patients of either sex and aged 11-59 years, with at least one third molar programmed for surgical removal, were included in the study. A descriptive statistical study was made. Results: The mean patient age was 27.6 ± 10.6 years. There were 2093 females (65.3%) and 1111 males (34.6%). In relation to the 4025 upper molars, extraction was decided for prophylactic reasons in 3827 cases (95.08%). Type A presentations were recorded in 1929 cases (47.9%), with a vertical position in 1931 teeth (48%). In relation to the 5123 lower third molars, extraction was likewise most often indicated for prophylactic reasons (4424 cases, 86.36%). A total of 2353 teeth corresponded to type A (45.9%), 2545 were class I cases (49.7%), and a mesioangular position was observed in 1850 cases (36.1%). Conclusions: The present study shows that in Mexican patients, upper third molars most often correspond to type A and class I, with a vertical position, while lower third molars predominantly correspond to type A and class I, with a mesioangular position. This information can help dental surgeons take better decisions before and after surgery, to the benefit of their patients. Key words:Third molars, retrospective review, surgical removal.