1376 THE ASSOCIATION OF POSTTRAUMATIC STRESS DISORDER WITH SEXUAL DYSFUNCTION IN MALE IRAQ AND AFGHANISTAN VETERANS
You have accessJournal of UrologySexual Function/Dysfunction/Andrology: Evaluation II1 Apr 20121376 THE ASSOCIATION OF POSTTRAUMATIC STRESS DISORDER WITH SEXUAL DYSFUNCTION IN MALE IRAQ AND AFGHANISTAN VETERANS Benjamin Breyer, Beth Cohen, Daniel Berterthal, Raymond Rosen, Thomas Neylan, and Karen Seal Benjamin BreyerBenjamin Breyer San Francisco, CA More articles by this author , Beth CohenBeth Cohen San Francisco, CA More articles by this author , Daniel BerterthalDaniel Berterthal San Francisco, CA More articles by this author , Raymond RosenRaymond Rosen Watertown, MA More articles by this author , Thomas NeylanThomas Neylan San Francisco, CA More articles by this author , and Karen SealKaren Seal San Francisco, CA More articles by this author View All Author Informationhttps://doi.org/10.1016/j.juro.2012.02.1803AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookTwitterLinked InEmail INTRODUCTION AND OBJECTIVES The main aim of this study was to examine the association between posttraumatic stress disorder (PTSD) and sexual dysfunction in male Iraq and Afghanistan veterans. METHODS This retrospective study used a Department of Veteran Affairs (VA) administrative database of Iraq and Afghanistan veterans enrolled in VA healthcare following military service separation between 10/07/01 through 09/30/11. ICD-9 diagnostic codes were used to identify PTSD and sexual dysfunction diagnoses, including erectile dysfunction (ED) and premature ejaculation (PE). Health services utilization and prescription medication data were also obtained. Descriptive statistics were used to compare the prevalence of sexual dysfunction in veterans with and without PTSD and generalized linear models were used to examine associations between PTSD and sexual dysfunction, utilization of urology services, and the prescription of medication for sexual dysfunction. RESULTS The median age of 643,599 Iraq and Afghanistan veterans in VA healthcare was 26 years; the prevalence of PTSD during the study period was 28.5%. The overall prevalence of sexual dysfunction, ED and PE were 5.2%, 2.7%, 0.1%, respectively. Male veterans with PTSD compared to those without PTSD were more likely to suffer from any sexual dysfunction (9.8% versus 3.3%, p=0.001), ED (5.2% versus 1.8%, p<.001) and PE (0.2% versus 0.1%, p <.001). Veterans with PTSD compared to those without PTSD were also more likely to receive a prescription for a phosphodiesterse inhibitor for ED (12.6% versus 3.4%, p<.001) and attend a urology clinic visit (8.1% versus 3.6%, p<.001). In a generalized linear model adjusted for sociodemographic, military service characteristics, and spinal cord injury, PTSD independently increased the risk of sexual dysfunction [adjusted risk ratio(ARR)=3.30, 95% Confidence Interval (CI) = 3.23-3.37]. After additional adjustment for medications used to treated PTSD (e.g. selective serotonin uptake inhibitors and other psychoactive medications), the risk decreased, but remained significant (ARR=1.60, 95% CI= 1.55-1.65). CONCLUSIONS Sexual dysfunction is prevalent among Iraq and Afghanistan veterans who have received PTSD diagnoses. While medications used to treat PTSD contribute to sexual dysfunction, PTSD or the symptoms of PTSD (e.g. avoidance, emotional numbing, and hyperarousal) also appear to independently impact sexual function. Awareness of the strong association between PTSD and sexual dysfunction may lead to more research and better treatment of this important quality of life issue. © 2012 by American Urological Association Education and Research, Inc.FiguresReferencesRelatedDetails Volume 187Issue 4SApril 2012Page: e559 Advertisement Copyright & Permissions© 2012 by American Urological Association Education and Research, Inc.MetricsAuthor Information Benjamin Breyer San Francisco, CA More articles by this author Beth Cohen San Francisco, CA More articles by this author Daniel Berterthal San Francisco, CA More articles by this author Raymond Rosen Watertown, MA More articles by this author Thomas Neylan San Francisco, CA More articles by this author Karen Seal San Francisco, CA More articles by this author Expand All Advertisement Advertisement PDF downloadLoading ...
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