Xinxiang Medical University

To understand the current status and influencing factors of self-management ability in peritoneal dialysis (PD) patients. This study employed an interpretive sequential mixed-methods approach and followed the STROBE and CONDITION guidelines. From June 2024 to February 2025, convenience sampling was used to survey 507 PD patients from three tertiary hospitals. Quantitative data were collected using five scales. Concurrently,purposesampling was used to conduct semi-structured interviews with 13 patients until data saturation was reached. Quantitative data were analyzed using SPSS 26.0, and qualitative data were analyzed thematically using Nvivo15. The results were integrated to provide a comprehensive understanding. The quantitative results showed that PD patients had a self-management ability score of [55.00 (45.00, 60.00)] out of a possible 96, indicating a moderately low level. Multiple linear regression identified age, educational attainment, monthly household income, dialysis age, understanding of the disease, mastery of health education content, frequency of follow-up, and self-efficacy as significant influencing factors. The qualitative interviews identified two themes (obstructive and promoting factors) and nine sub-themes. The integration of results showed that qualitative findings confirmed and complemented the quantitative associations. The self-management ability of PD patients is moderately low. Medical staff should enhance the self-efficacy and social support of PD patients based on the influencing factors of their self-management ability, increase the frequency of follow-up, pay attention to PD patients with low education, advanced age and other types, strengthen training and monitoring for complications, and carry out targeted intervention to improve the self-management ability of PD patients.

Highly sensitive detection of trimethylamine (TMA) concentration in complex monitoring environments is a pivotal technology for food freshness assessment. Herein, through an active-site engineering strategy, PdRu-modified hierarchical In2O3 nanoflowers were successfully prepared by self-assembly of mesoporous nanosheets. The 3D interconnected pore system significantly promotes the diffusion and mass transfer of TMA, while notably enhancing the interfacial collision efficiency in gas-sensitive reactions. The PdRu/In2O3-1.0-based sensor exhibits a sensitivity of 71.9 at 50ppm, with a detection limit of 200ppb, while optimizing the operating temperature range from 200°C to 140°C. Simultaneously, machine learning-based analysis confirms the high selectivity, enabling it to identify TMA in ammonia-containing binary mixtures with an accuracy quantified at 99.3%. Furthermore, density functional theory calculations combined with in situ/ex situ characterizations revealed that bimetallic oxygen spillover effects optimize oxygen transfer kinetics, reduce the activation energy barrier, and collectively enhance the trimethylamine adsorption energy (ΔEads = -0.51eV) through orbital hybridization and charge redistribution mechanisms. Leveraging the advanced sensing strategy, the wireless portable sensing system is engineered for the rapid and non-destructive evaluation of seafood freshness, enabling quality detection and cloud data transmission throughout the entire industry chain.