Yamal Multidisciplinary College

Subject. The article discusses resource balances necessary to ensure the fulfillment of objectives of innovation process stages. Objectives. The aim is to develop tools to ensure the resource balance of stages of innovation processes, through the use of a morphological table. Methods. The study rests on the systems approach to the subject area, methods of synthesis, comparison, analogies, generalization, and classification. Results. The paper offers morphological tables of ensuring the resource requirements of innovation process stages at the micro and macro levels. Conclusions. The scientific and practical significance of the results is in the possibility of using morphological analysis as a decision-making tool to ensure a balance between the resource needs of the stages of innovation processes in the implementation of strategic development directions at the micro and macro levels.

We analyze the layer of mythological vocabulary of Tambov patois that functions in the structure of formulas for intimidating children as communicative type texts, related to the sphere of traditional spiritual culture. We identify the structure features of such texts; composition of in-timidating characters; features of their lexical expression, portrait characteristics (local affiliation, presence of hair, body pathologies) and harmful functions. Mythological characters, serving as in-timidators, are deprived most of semantic features; the reduction of such names initial semantics can be compensated by the ideophonic features of these characters' nominations; the uncertainty of characters' appearance for intimidating children determines the inclusion in this set of subjects; the prevalence of folk pedagogical methods of intimidation is associated with the role played by fear and fright in the culture of childhood. For traditional culture bearers, intimidation can be recognized as a significant element of folk pedagogy, since it functioned not only on the verbal, but also on the actional levels.

Novel hybrid nanocomposites of Cu2O nanoparticles (NPs) partially embedded in CuO nanowires (NWs) were produced by simple thermal reduction of CuO NWs in a vacuum. It is found that most Cu2O NPs adopt two regular shapes, one being cubic and the other being octahedral. The shape selection of the Cu2O nanocrystals is governed by the orientation relationship between Cu2O NPs and CuO NWs. The formation of such hierarchical hybrid nanostructures is induced by the topotactic reduction of CuO NWs. Compared with pure CuO NWs, the polyhedral Cu2O NP-CuO NW hierarchical hybrid nanostructures exhibit enhanced ability to photodegrade methyl orange under visible light, which is attributed to the synergic effects of CuO NWs and Cu2O NPs.

We report single-molecule detection of Hg(2+) by threading an Hg(2+)-mediated DNA duplex through α-hemolysin nanopores, which generates characteristic three-level current patterns and enables the unambiguous detection of Hg(2+). This strategy precludes any background interference and features high sensitivity and selectivity. Moreover, the platform could be readily integrated with aptamers and molecular beacons, offering extended possibilities for the construction of a new DNA-based nanopore sensing system.

Lung or heart-lung transplantation is a useful therapy in life-threatening pulmonary disorders during childhood. Cyclosporine A is a major immunosuppressive treatment but has a number of adverse effects including nephrotoxicity. There have been no reports on the long-term evolution of renal function in a large series of paediatric pulmonary transplantation recipients. We examined 19 patients followed up for at least 3 years after pulmonary transplantation. The mean time of follow-up was 5.36 years. Kidney function was evaluated by calculation of glomerular filtration rate (GFR) according the Schwartz formula. The GFR was normal before transplantation in all patients. The short-term evolution of GFR was marked by a significant drop during the first and until the 6th month. Then, regardless of the level reached at the end of the 6th month, the GFR remained stable in all patients except one until the end of follow-up. At the end of follow-up, 31% had normal GFR, 57% had mild chronic renal failure, and 5% had advanced renal failure. Hypertension was frequent and associated with renal failure. Paediatric pulmonary recipients showed evidence of long-term cyclosporine A-associated nephrotoxicity. Most of this toxicity occurred during the first 6 months.