• Home
  • Search
  • 3D Compressed Convolutional Neural Network Differentiates Neuromyelitis Optical Spectrum Disorders From Multiple Sclerosis Using Automated White Matter Hyperintensities Segmentations.
  • Cite Icon25
  • https://doi.org/10.3389/fphys.2020.612928Copy DOI Icon

3D Compressed Convolutional Neural Network Differentiates Neuromyelitis Optical Spectrum Disorders From Multiple Sclerosis Using Automated White Matter Hyperintensities Segmentations.

Show More
  • Abstract
  • Highlights & Summary
  • PDF
  • Literature Map
  • References
  • Citations
  • Similar Papers
Abstract

BackgroundMagnetic resonance imaging (MRI) has a wide range of applications in medical imaging. Recently, studies based on deep learning algorithms have demonstrated powerful processing capabilities for medical imaging data. Previous studies have mostly focused on common diseases that usually have large scales of datasets and centralized the lesions in the brain. In this paper, we used deep learning models to process MRI images to differentiate the rare neuromyelitis optical spectrum disorder (NMOSD) from multiple sclerosis (MS) automatically, which are characterized by scattered and overlapping lesions.MethodsWe proposed a novel model structure to capture 3D MRI images’ essential information and converted them into lower dimensions. To empirically prove the efficiency of our model, firstly, we used a conventional 3-dimensional (3D) model to classify the T2-weighted fluid-attenuated inversion recovery (T2-FLAIR) images and proved that the traditional 3D convolutional neural network (CNN) models lack the learning capacity to distinguish between NMOSD and MS. Then, we compressed the 3D T2-FLAIR images by a two-view compression block to apply two different depths (18 and 34 layers) of 2D models for disease diagnosis and also applied transfer learning by pre-training our model on ImageNet dataset.ResultsWe found that our models possess superior performance when our models were pre-trained on ImageNet dataset, in which the models’ average accuracies of 34 layers model and 18 layers model were 0.75 and 0.725, sensitivities were 0.707 and 0.708, and specificities were 0.759 and 0.719, respectively. Meanwhile, the traditional 3D CNN models lacked the learning capacity to distinguish between NMOSD and MS.ConclusionThe novel CNN model we proposed could automatically differentiate the rare NMOSD from MS, especially, our model showed better performance than traditional3D CNN models. It indicated that our 3D compressed CNN models are applicable in handling diseases with small-scale datasets and possess overlapping and scattered lesions.

Loading PDF

Similar Papers
  • Conference Article
  • Citations15

Impact of Variation in Number of Channels in CNN Classification model for Cervical Cancer Detection

  • Sep 03, 2021
  • Nitin Kumar Chauhan +1
  • Research Article
  • Citations1

Enhanced Convolutional Neural Network Framework for Region of Interest-Based Efficient Bone Cancer Detection in Medical Imaging

  • Mar 14, 2025
  • Journal of Information Systems Engineering and Management
  • Sagarika Saka
  • Conference Article
  • Citations6

Review of Deep Learning Using Convolutional Neural Network Model

  • Mar 05, 2024
  • Engineering headway
  • Ari Kurniawan +5
  • Research Article
  • Citations41

Estimation and uncertainty analysis of groundwater quality parameters in a coastal aquifer under seawater intrusion: a comparative study of deep learning and classic machine learning methods.

  • Aug 08, 2022
  • Environmental Science and Pollution Research
  • Mehmet Taşan +2
  • PDF
  • Research Article
  • Citations3

LaM-2SRN: A Method Which Can Enhance Local Features and Detect Moving Objects for Action Recognition

  • Jan 01, 2020
  • IEEE Access
  • Yangyang Qiao +2
  • Research Article
  • Citations92

Keratoconus Screening Based on Deep Learning Approach of Corneal Topography

  • Sep 25, 2020
  • Translational Vision Science & Technology
  • Bo-I Kuo +9
  • Research Article
  • Citations140

Understanding the learning mechanism of convolutional neural networks in spectral analysis

  • Apr 08, 2020
  • Analytica Chimica Acta
  • Xiaolei Zhang +8
  • Research Article

Predicting Within-City Variations in Ultrafine Particle and Black Carbon Concentrations in Bucaramanga, Columbia Using Open Source Data and Images

  • Aug 23, 2021
  • ISEE Conference Abstracts
  • Marshall Lloyd +7
  • Conference Article
  • Citations1

Automatic Early Detection of Potato Blight Disease Using Deep Neural Networks

  • Dec 07, 2024
  • Shibdas Dutta +2
  • Research Article
  • Citations100

VideoGasNet: Deep learning for natural gas methane leak classification using an infrared camera

  • Jul 19, 2021
  • Energy
  • Jingfan Wang +4
  • Conference Article
  • Citations9

Improved Convolutional Neural Network Based on Multi-head Attention Mechanism for Industrial Process Fault Classification

  • Nov 20, 2020
  • Wenzhi Cui +2
  • Research Article
  • Citations11

Predicting the thermal conductivity of polymer composites with one-dimensional oriented fillers using the combination of deep learning and ensemble learning

  • Nov 08, 2024
  • Energy and AI
  • Yinzhou Liu +5
  • Research Article

Comparative Analysis of Fine-tuning Multiple Pre- Trained Convolutional Neural Network (CNN) Models for Oryza Sativa Disease Detection

  • Sep 22, 2023
  • International Journal of Computer Applications
  • Roky Das +1
  • PDF
  • Research Article
  • Citations573

Deep learning for lung cancer prognostication: A retrospective multi-cohort radiomics study

  • Nov 30, 2018
  • PLoS Medicine
  • Ahmed Hosny +9
  • Research Article

A novel in-loop filtering mechanism of HEVC based on 3D sub-bands and CNN processing

  • Feb 18, 2019
  • Signal, Image and Video Processing
  • Dacheng Zhang +3
Cactus Communications logo

Copyright 2026 Cactus Communications. All rights reserved.