A Brief Review on Deep Learning Based Software Vulnerability Detection

IntroductionAccurate classification of brain tumors from MRI scans is a critical task for improving patient outcomes. Machine learning (ML) and deep learning (DL) methods have shown promise in this domain, but their relative performance remains unclear.MethodsThis study evaluates several ML and DL techniques using the BraTS 2024 dataset. The models assessed include traditional algorithms such as Random Forest and advanced deep learning architectures including Simple CNN, VGG16, VGG19, ResNet50, Inception-ResNetV2, and EfficientNet. Preprocessing strategies were applied to optimize model performance.ResultsThe Random Forest classifier achieved the highest accuracy of 87%, outperforming all deep learning models, which achieved accuracy in the range of 47% to 70%. This indicates that traditional ML approaches can sometimes surpass state-of-the-art DL methods in tumor classification tasks.DiscussionThe findings highlight the importance of model selection and parameter tuning in automated brain tumor diagnosis. While deep learning models are generally considered standard for image analysis, Random Forest demonstrated superior performance in this context. This underscores the need for fine-grained consideration of dataset characteristics, computational resources, and diagnostic requirements.ConclusionThe study shows that carefully selected and optimized ML approaches can improve tumor classification and support more accurate and efficient diagnostic systems for brain tumor patients.

Deep learning methods have become popular among researchers in the field of fault detection. However, their performance depends on the availability of big datasets. To overcome this problem researchers started applying transfer learning to achieve good performance from small available datasets, by leveraging multiple prediction models over similar machines and working conditions. However, the influence of negative transfer limits their application. Negative transfer among prediction models increases when the environment and working conditions are changing continuously. To overcome the effect of negative transfer, we propose a novel deep transfer learning method, coined deep boosted transfer learning, for wind turbine gearbox fault detection that prevents negative transfer and only focuses on relevant information from the source machine. The proposed method is an instance-based deep transfer learning method that updates the weights of the source and the target machine training samples separately. The weights of different source training samples are gradually decreased to reduce the impact on the final model. The proposed method is verified by the Case Western Reserve University bearing and real field wind farm datasets. The results show that the proposed method ignores negative transfer and achieves higher accuracy compared to standard deep learning and deep transfer learning methods.

Less than 10% of patients with cancer have detectable pathogenic germline alterations, which may be partially due to incomplete pathogenic variant detection. To evaluate if deep learning approaches identify more germline pathogenic variants in patients with cancer. A cross-sectional study of a standard germline detection method and a deep learning method in 2 convenience cohorts with prostate cancer and melanoma enrolled in the US and Europe between 2010 and 2017. The final date of clinical data collection was December 2017. Germline variant detection using standard or deep learning methods. The primary outcomes included pathogenic variant detection performance in 118 cancer-predisposition genes estimated as sensitivity, specificity, positive predictive value (PPV), and negative predictive value (NPV). The secondary outcomes were pathogenic variant detection performance in 59 genes deemed actionable by the American College of Medical Genetics and Genomics (ACMG) and 5197 clinically relevant mendelian genes. True sensitivity and true specificity could not be calculated due to lack of a criterion reference standard, but were estimated as the proportion of true-positive variants and true-negative variants, respectively, identified by each method in a reference variant set that consisted of all variants judged to be valid from either approach. The prostate cancer cohort included 1072 men (mean [SD] age at diagnosis, 63.7 [7.9] years; 857 [79.9%] with European ancestry) and the melanoma cohort included 1295 patients (mean [SD] age at diagnosis, 59.8 [15.6] years; 488 [37.7%] women; 1060 [81.9%] with European ancestry). The deep learning method identified more patients with pathogenic variants in cancer-predisposition genes than the standard method (prostate cancer: 198 vs 182; melanoma: 93 vs 74); sensitivity (prostate cancer: 94.7% vs 87.1% [difference, 7.6%; 95% CI, 2.2% to 13.1%]; melanoma: 74.4% vs 59.2% [difference, 15.2%; 95% CI, 3.7% to 26.7%]), specificity (prostate cancer: 64.0% vs 36.0% [difference, 28.0%; 95% CI, 1.4% to 54.6%]; melanoma: 63.4% vs 36.6% [difference, 26.8%; 95% CI, 17.6% to 35.9%]), PPV (prostate cancer: 95.7% vs 91.9% [difference, 3.8%; 95% CI, -1.0% to 8.4%]; melanoma: 54.4% vs 35.4% [difference, 19.0%; 95% CI, 9.1% to 28.9%]), and NPV (prostate cancer: 59.3% vs 25.0% [difference, 34.3%; 95% CI, 10.9% to 57.6%]; melanoma: 80.8% vs 60.5% [difference, 20.3%; 95% CI, 10.0% to 30.7%]). For the ACMG genes, the sensitivity of the 2 methods was not significantly different in the prostate cancer cohort (94.9% vs 90.6% [difference, 4.3%; 95% CI, -2.3% to 10.9%]), but the deep learning method had a higher sensitivity in the melanoma cohort (71.6% vs 53.7% [difference, 17.9%; 95% CI, 1.82% to 34.0%]). The deep learning method had higher sensitivity in the mendelian genes (prostate cancer: 99.7% vs 95.1% [difference, 4.6%; 95% CI, 3.0% to 6.3%]; melanoma: 91.7% vs 86.2% [difference, 5.5%; 95% CI, 2.2% to 8.8%]). Among a convenience sample of 2 independent cohorts of patients with prostate cancer and melanoma, germline genetic testing using deep learning, compared with the current standard genetic testing method, was associated with higher sensitivity and specificity for detection of pathogenic variants. Further research is needed to understand the relevance of these findings with regard to clinical outcomes.

Cardiovascular diseases (CVDs) remain a leading cause of global mortality, underscoring the urgent need for early and accurate diagnosis. Electrocardiograms (ECGs) are a widely used, noninvasive tool for detecting cardiac abnormalities, but manual interpretation can be time- consuming and prone to error. This study explores advanced machine learning (ML) and deep learning (DL) methods to improve the detection of CVDs from ECG images, leveraging their ability to analyze complex patterns with high precision. Models such as Convolutional Neural Networks (CNNs), Vision Transformers (ViTs), and ensemble frameworks are utilized, alongside traditional ML models like XGBoost, CatBoost, and LightGBM. The performance of these models is evaluated based on precision, recall, F1-score, and accuracy. Results show that DL models, particularly an ensemble of CNN and ViT, achieve superior accuracy , outperforming standalone ML methods. Furthermore, an ensemble of XGBoost, CatBoost, and LightGBM achieves competitive results, while Optuna-tuned XGBoost further enhances ML performance. The findings highlight the potential of combining ML and DL techniques for robust and reliable CVD detection in ECG images. This research demonstrates the promise of AI-driven solutions in advancing medical diagnostics and supports the integration of automated systems for early detection of cardiovascular diseases.

The clinical utility of regional strain measurements in echocardiography is challenged by suboptimal reproducibility. In this study, we aimed to evaluate the test-retest reproducibility of regional longitudinal strain (RLS) per coronary artery perfusion territory (RLSTerritory) and basal-to-apical level of the left ventricle (RLSLevel), measured by a novel fully automated deep learning (DL) method based on point tracking. We measured strain in a dual-centre test-retest data set that included 40 controls and 40 patients with suspected non-ST elevation acute coronary syndrome. Two consecutive echocardiograms per subject were recorded by different operators. The reproducibility of RLSTerritory and RLSLevel measured by the DL method and by three experienced observers using semi-automatic software (2D Strain, EchoPAC, GE HealthCare) was evaluated as minimal detectable change (MDC). The DL method had MDC for RLSTerritory and RLSLevel ranging from 3.6 to 4.3%, corresponding to a 33-35% improved reproducibility compared with the inter- and intraobserver scenarios (MDC 5.5-6.4% and 4.9-5.4%). Furthermore, the DL method had a lower variance of test-retest differences for both RLSTerritory and RLSLevel compared with inter- and intraobserver scenarios (all P < 0.001). Bland-Altman analyses demonstrated superior reproducibility by the DL method for the whole range of strain values compared with the best observer scenarios. The feasibility of the DL method was 93% and measurement time was only 1 s per echocardiogram. The novel DL method provided fully automated measurements of RLS, with improved test-retest reproducibility compared with semi-automatic measurements by experienced observers. RLS measured by the DL method has the potential to advance patient care through a more detailed, more efficient, and less user-dependent clinical assessment of myocardial function.

The cirrhosis disease represents the final stage of hepatitis, characterized by the death of liver cells and irreversible liver damage. Although there are some methods used in the prediction of cirrhosis, especially those utilizing various artificial intelligence techniques, it is still difficult to accurately predict cirrhosis. The aim of this research is to detect cirrhosis by focusing on deep learning methods. In addition to analyzing the performance of deep learning methods for cirrhosis prediction, the study also compares the performance of traditional machine learning algorithms with deep learning techniques. Decision Tree (DT), k-Nearest Neighbors (kNN), Random Forest (RF) and Logistic Regression (LR) algorithms are used in order to achieve these goals. Considering the relatively lower performance of some of these algorithms, Deep Neural Networks performed the classification accurately. In the dataset used in the study, there were 362 patients with cirrhosis and 1023 without cirrhosis. Model performance showed that deep neural networks achieved high classification performance with metrics such as 95.96% accuracy. According to the results, deep learning methods showed strong performance, providing high accuracy and sensitivity for cirrhosis prediction alongside traditional machine learning methods.

Background: Customer churn significantly impacts business revenues. Machine Learning (ML) and Deep Learning (DL) methods are increasingly adopted to predict churn, yet a systematic synthesis of recent advancements is lacking. Objectives: This systematic review evaluates ML and DL approaches for churn prediction, identifying trends, challenges, and research gaps from 2020 to 2024. Data Sources: Six databases (Springer, IEEE, Elsevier, MDPI, ACM, Wiley) were searched via Lens.org for studies published between January 2020 and December 2024. Study Eligibility Criteria: Peer-reviewed original studies applying ML/DL techniques for churn prediction were included. Reviews, preprints, and non-peer-reviewed works were excluded. Methods: Screening followed PRISMA 2020 guidelines. A two-phase strategy identified 240 studies for bibliometric analysis and 61 for detailed qualitative synthesis. Results: Ensemble methods (e.g., XGBoost, LightGBM) remain dominant in ML, while DL approaches (e.g., LSTM, CNN) are increasingly applied to complex data. Challenges include class imbalance, interpretability, concept drift, and limited use of profit-oriented metrics. Explainable AI and adaptive learning show potential but limited real-world adoption. Limitations: No formal risk of bias or certainty assessments were conducted. Study heterogeneity prevented meta-analysis. Conclusions: ML and DL methods have matured as key tools for churn prediction, yet gaps remain in interpretability, real-world deployment, and business-aligned evaluation. Systematic Review Registration: Registered retrospectively in OSF.

AI-generated content (AIGC) in the context of dermoscopic image analysis describes the application of artificial intelligence (AI) approaches to produce synthetic images for training and enriching machine learning (ML) methods. In dermatology, where dermoscopic images are essential in skin lesion detection, AIGC helps overcome the challenges of inadequate datasets and class imbalances. By employing advanced generative complex systems like Generative Adversarial Networks (GANs), AIGC will simulate different dermoscopic conditions by generating realistic-view synthetic images. These AI-generated images help to enhance the training dataset, contributing to the ML models with many widespread and varied sets of instances. This aids in increasing the ability of the model to precisely predict and generalize while handling new, unnoticed dermoscopic images. Deep learning (DL) methods, specifically convolutional neural networks (CNNs), can provide a massive breakthrough in an extensive range of computer vision (CV) tasks of complex systems, predominantly by exploiting large-scale annotated datasets. This paper develops a GAN-based Synthetic Medical Image Augmentation for the imbalanced Dermoscopic Image Analysis (GANSMIA-CDIA) method. The GANSMIA-CDIA technique’s primary target is exploiting the GAN model for synthetic image generation to handle class imbalance data problems. In addition, the GANSMIA-CDIA technique diagnoses the melanoma using the optimal DL model. The GANSMIA-CDIA technique applies a contrast enhancement process for the noise eradication process. The GANSMIA-CDIA technique follows a feature fusion method comprising different DL methods such as MobileNetV2, AlexNet, ResNet50, and Inceptionv3 to learn feature patterns in the preprocessed images. Meanwhile, the Social Network Search (SNS) technique is utilized for the hyperparameter tuning process. Also, the bidirectional long short-term memory (BiLSTM) technique is implemented to detect and classify melanoma. A series of simulations were performed on the standard dermoscopic image dataset to evaluate the performance of the GANSMIA-CDIA technique. The experimental values indicate the excellence of the GANSMIA-CDIA technique over existing techniques.

ObjectivePituitary adenomas are the most common type of pituitary disorders, which usually occur in young adults and often affect the patient’s physical development, labor capacity and fertility. Clinical free texts noted in electronic medical records (EMRs) of pituitary adenomas patients contain abundant diagnosis and treatment information. However, this information has not been well utilized because of the challenge to extract information from unstructured clinical texts. This study aims to enable machines to intelligently process clinical information, and automatically extract clinical named entity for pituitary adenomas from Chinese EMRs.MethodsThe clinical corpus used in this study was from one pituitary adenomas neurosurgery treatment center of a 3A hospital in China. Four types of fine-grained texts of clinical records were selected, which included notes from present illness, past medical history, case characteristics and family history of 500 pituitary adenoma inpatients. The dictionary-based matching, conditional random fields (CRF), bidirectional long short-term memory with CRF (BiLSTM-CRF), and bidirectional encoder representations from transformers with BiLSTM-CRF (BERT-BiLSTM-CRF) were used to extract clinical entities from a Chinese EMRs corpus. A comprehensive dictionary was constructed based on open source vocabularies and a domain dictionary for pituitary adenomas to conduct the dictionary-based matching method. We selected features such as part of speech, radical, document type, and the position of characters to train the CRF-based model. Random character embeddings and the character embeddings pretrained by BERT were used respectively as the input features for the BiLSTM-CRF model and the BERT-BiLSTM-CRF model. Both strict metric and relaxed metric were used to evaluate the performance of these methods.ResultsExperimental results demonstrated that the deep learning and other machine learning methods were able to automatically extract clinical named entities, including symptoms, body regions, diseases, family histories, surgeries, medications, and disease courses of pituitary adenomas from Chinese EMRs. With regard to overall performance, BERT-BiLSTM-CRF has the highest strict F1 value of 91.27% and the highest relaxed F1 value of 95.57% respectively. Additional evaluations showed that BERT-BiLSTM-CRF performed best in almost all entity recognition except surgery and disease course. BiLSTM-CRF performed best in disease course entity recognition, and performed as well as the CRF model for part of speech, radical and document type features, with both strict and relaxed F1 value reaching 96.48%. The CRF model with part of speech, radical and document type features performed best in surgery entity recognition with relaxed F1 value of 95.29%.ConclusionsIn this study, we conducted four entity recognition methods for pituitary adenomas based on Chinese EMRs. It demonstrates that the deep learning methods can effectively extract various types of clinical entities with satisfying performance. This study contributed to the clinical named entity extraction from Chinese neurosurgical EMRs. The findings could also assist in information extraction in other Chinese medical texts.

This review paper examines the current state of lung disease diagnosis based on deep learning (DL) methods. Lung diseases, such as Pneumonia, TB, Covid-19, and lung cancer, are significant causes of morbidity and mortality worldwide. Accurate and timely diagnosis of these diseases is essential for effective treatment and improved patient outcomes. DL methods, which utilize artificial neural networks to extract features from medical images automatically, have shown great promise in improving the accuracy and efficiency of lung disease diagnosis. This review discusses the various DL methods that have been developed for lung disease diagnosis, including convolutional neural networks (CNNs), deep neural networks (DNNs), and generative adversarial networks (GANs). The advantages and limitations of each method are discussed, along with the types of medical imaging techniques used, such as X-ray and computed tomography (CT). In addition, the review discusses the most commonly used performance metrics for evaluating the performance of DL for lung disease diagnosis: the area under the curve (AUC), sensitivity, specificity, F1-score, accuracy, precision, and the receiver operator characteristic curve (ROC). Moreover, the challenges and limitations of using DL for lung disease diagnosis, including the limited availability of annotated data, the variability in imaging techniques and disease presentation, and the interpretability and generalizability of DL models, are highlighted in this paper. Furthermore, strategies to overcome these challenges, such as transfer learning, data augmentation, and explainable AI, are also discussed. The review concludes with a call for further research to address the remaining challenges and realize DL's full potential for improving lung disease diagnosis and treatment.

Generating an accurate model of the subsurface for the purpose of assessing the feasibility of a CO2 storage site is crucial. In particular, how faults are interpreted is likely to influence the predicted capacity and integrity of the reservoir; whether this is through identifying high-risk areas along the fault, where fluid is likely to flow across the fault, or by assessing the reactivation potential of the fault with increased pressure, causing fluid to flow up the fault. New technologies allow users to interpret faults effortlessly, and in much quicker time, using methods such as deep learning (DL). These DL techniques use knowledge from neural networks to allow end users to compute areas where faults are likely to occur. Although these new technologies may be attractive due to reduced interpretation time, it is important to understand the inherent uncertainties in their ability to predict accurate fault geometries. Here, we compare DL fault interpretation versus manual fault interpretation, and we can see distinct differences to those faults where significant ambiguity exists due to poor seismic resolution at the fault; we observe an increased irregularity when DL methods are used over conventional manual interpretation. This can result in significant differences between the resulting analyses, such as fault reactivation potential. Conversely, we observe that well-imaged faults indicate a close similarity between the resulting fault surfaces when DL and manual fault interpretation methods are used; hence, we also observe a close similarity between any attributes and fault analyses made.

Automatic assessment of pain based on deep learning methods: A systematic review

As modern server systems increase in volume and density, more and more hardware failures are generated, resulting in system breakdown. The conventional mechanisms for monitoring and checking the behavior of hardware parts, such as the hard disk drive (HDD), the RAM and the CPU, are not considered a dynamic approach for hardware failure prediction. On the other hand, machine learning (ML) and deep learning (DL) methods can assist to effectively predict hardware errors at a sufficient amount of time before they actually occur. In this work, a survey is presented on hardware failure prediction techniques for servers using ML and DL methods, with a focus on HDD, RAM and CPU issues. These techniques are categorized based on the ML or DL algorithm they use for the prediction process. The basic features of each work (used dataset, system type, HDD/RAM/CPU focus, error types etc.) are demonstrated. Additionally, certain statistic results from the various prediction methods are displayed, concluding in some crucial discussion on the existing literature.

&lt;p class="0abstract"&gt;The research aimed to conduct an extensive study of machine learning and deep learning methods in cybersecurity. To accomplish the objectives, the research carried out a qualitative study based on secondary data collection to review the available studies and literature. The research has examined three machine learning methods and three deep learning methods to study the most popular techniques used in cybersecurity. During the research, the working mechanism of each method was studied along with their strengths and weaknesses. Also, a comparative discussion has been made to examine the most effective method for cybersecurity. Limitations in the current literature were also identified, and future direction is also given to target and develop the weak areas of machine learning and deep learning methods.&lt;em&gt; &lt;/em&gt;&lt;strong&gt;&lt;/strong&gt;&lt;/p&gt;

Excessive withdrawal of groundwater for agricultural irrigation can cause seawater intrusion into coastal aquifers. Such a case will in turn results in deterioration of irrigation water quality. Determination of irrigation water quality with traditional methods is a time-consuming and costly process. However, machine learning algorithms can be useful tools for modeling and estimating groundwater quality used for irrigation water purposes. In this study, TDS, PS, SAR, and Cl parameters of groundwater were estimated with models based on EC and pH variables. For this purpose, prediction performances of two different deep learning methods (convolutional neural network (CNN) and deep neural network (DNN)) and two different classical machine learning (Random Forest (RF) and extreme gradient boosting (XGBoost)) methods were compared. In addition, predictive uncertainty of the models was determined by quantile regression (QR) analysis. Performance criteria and results of uncertainty analysis revealed that CNN (in testing phase, NSE = 0.95 for TDS, NSE = 0.96 for PS, NSE = 0.67 for SAR and NSE = 0.93 for CI) and DNN (in testing phase, NSE = 0.91 for TDS, NSE = 0.91 for PS, NSE = 0.57 for SAR and NSE = 0.94 for Cl) models had quite a close performance in estimation of TDS, PS, SAR, and Cl parameters and higher than the other two classical machine learning methods. As a result, the CNN model can be considered the best performing model in estimating all quality parameters due to the highest NSE and lowest RMSE values. In addition, the Taylor diagram showed that the values estimated using the CNN model had the highest correlation with the measured data. It was determined that the model with the lowest uncertainty based on the PICP statistics was DNN, followed by the CNN model. However, the CNN model has predicted outliers more accurately. Present findings proved that deep learning models could offer efficient tools for predicting irrigation water quality parameters.