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  • A Comparison of Machine Learning Techniques for Diagnosing Multiple Myeloma
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  • https://doi.org/10.1007/978-3-030-87897-9_43Copy DOI Icon

A Comparison of Machine Learning Techniques for Diagnosing Multiple Myeloma

  • Jan 1, 2021
  • Luveshan Marimuthu +3 more
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Abstract

Multiple myeloma is a type of bone marrow cancer. Patient’s blood samples are analysed from protein gel strips and densitometer graphs which are then interpreted by a pathologist to diagnose multiple myeloma. This manual process of diagnosis is slow which is problematic as patients need to be diagnosed as soon as possible in order to prevent the condition from worsening, hence the need to automate this process. Given the success of machine learning in diagnosing diseases from images, this study investigates the use of machine learning approaches for the diagnosis of multiple myeloma. This is the first study investigating the automation of this process and hence presents a novel application of machine learning. The study compares machine learning approaches, artificial neural networks, convolutional neural networks, random forests and support vector machines, for the diagnosis of multiple myeloma from gel strips and densitometer graphs. The study has revealed that convolutional neural networks, specifically VGG16, is the most suitable approach for the detection of multiple myeloma.

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