A robust possibilistic programming approach for pharmaceutical supply chain network design

The increasing level of customer awareness and application of environmental laws by governments, on the one hand, and the increasing number of competitors, on the other hand, has obliged industry owners to include green activities in the design of the supply chain network. Green activities include any type of action that reduces environmental degradation. Hence, this study seeks to develop a bi-objective, mixed integer linear programming (MILP) model for designing a green supply chain network. In the proposed model, the minimisation of costs and detrimental environmental effects are discussed. LP metric method is used to solve the bi-objective model and the proposed model is run by using simulated data in small and medium sizes in GAMS software. Finally, the model sensitivity analysis is measured in order to evaluate the validity and performance of the proposed model by using demand-driven scenarios. The results of this model indicate the effectiveness of the proposed model.

Optimizing a bi-objective multi-product multi-period three echelon supply chain network with warehouse reliability

Robust optimization for the cyclic hoist scheduling problem

Allocation of products to a heterogeneous fleet of trucks in a cross-docking center based on carbon emissions and costs in food and beverage industry: Novel uncertain solution approaches

The growing rate of population and technological advancement have led to an increase in natural resource consumption, which has caused irreparable damage to the environment. The implementation of green supply chain management is one of the most effective ways to deal with environmental degradation. Therefore, in this paper, a bi-objective mixed integer linear programming model is developed to design a green supply chain network. In the proposed model, the possibility of customer storage, being faced with shortage, locating of distribution centres, green vehicle routing problem, split delivery, multi-depot vehicle routing problem (VRP), capacitated VRP, and uncertainty in demands will be considered. The aim of the proposed model is to minimise the total cost and total shortages simultaneously and, therefore, a fuzzy solution approach is applied for this purpose. The results of implementing this model in a production chain of automotive parts in Iran indicate the exact and efficient performance of the proposed model.

This paper presents multiple readings to solve a vehicle routing problem with pickup and delivery (VRPPD) based on a real-life case study. Compared to theoretical problems, real-life ones are more difficult to address due to their richness and complexity. To handle multiple points of view in modeling our problem, we developed three different Mixed Integer Linear Programming (MILP) models, where each model covers particular constraints. The suggested models are designed for a mega poultry company in Tunisia, called CHAHIA. Our mission was to develop a prototype for CHAHIA that helps decision-makers find the best path for simultaneously delivering the company’s products and collecting the empty boxes. Based on data provided by CHAHIA, we conducted computational experiments, which have shown interesting and promising results.

A robust bi-objective mathematical model for disaster rescue units allocation and scheduling with learning effect

Bi-objective unrelated parallel machine joint scheduling of jobs and preventive maintenance with a dynamic speed-scaling technique

Bioethanol supply chain network design considering land characteristics

The management of hazardous wastes in regions is required to design a multi-echelon network with multiple facilities including recycling, treatment and disposal centers servicing the transportation, recycling, treatment and disposal procedures of hazardous wastes and waste residues. The multi-period network design problem within is to determine the location of waste facilities and allocation/transportation of wastes/residues in each period during the planning horizon, such that the total cost and total risk in the location and transportation procedures are minimized. With consideration of the life cycle capacity of disposal centers, we formulate the problem as a bi-objective mixed integer linear programming model in which a unified modeling strategy is designed to describe the closing of existing waste facilities and the opening of new waste facilities. By exploiting the characteristics of the proposed model, an augmented -constraint algorithm is developed to solve the model and find highly qualified representative non-dominated solutions. Finally, computational results of a realistic case demonstrate that our algorithm can identify obviously distinct and uniformly distributed representative non-dominated solutions within reasonable time, revealing the trade-off between the total cost and total risk objectives efficiently. Meanwhile, the multi-period network design optimization is superior to the single-period optimization in terms of the objective quality.

Green-resilient supply chain network design for perishable products considering route risk and horizontal collaboration under robust interval-valued type-2 fuzzy uncertainty: A case study in food industry

Modeling side slopes in vertical alignment resource road construction using convex optimization

In this paper, a supply chain management problem from a real case study is modeled and solved. A company in Pakistan wanted to outsource part of its warehousing activity to a third party logistics (3PL) provider. Consequently, the company had to decide on where to rent space in the 3PL warehouses. Knowing that such a strategic decision is affected by tactical and operational decisions, the problem is presented as a facility location problem integrating production, inventory, and distribution decisions. The problem is formulated as a mixed integer linear programming model which minimizes the total cost composed of location, distribution, production, and inventory costs. Several constraints specific to the situation and policy of the company were considered. A thorough analysis was done on the results obtained with respect to formulation efficiency, sensitivity analysis, and distribution of costs. In addition to the solution of the company problem, a set of 1215 problem instances was generated by varying five types of relevant costs in a full factorial manner. The solution of the generated problems always suggests to open in the same two locations and the integrality gaps averaged 0.062 % with a maximum of 0.102 %. On average, the major components of the total cost are production cost (96.6 %), transportation costs (2.7 %), and inventory holding costs (0.38 %). The total warehouse opening cost accounted for less than 0.05 % of the total costs.

To support the selection of food items for FFQs in such a way that the amount of information on all relevant nutrients is maximised while the food list is as short as possible. Selection of the most informative food items to be included in FFQs was modelled as a Mixed Integer Linear Programming (MILP) model. The methodology was demonstrated for an FFQ with interest in energy, total protein, total fat, saturated fat, monounsaturated fat, polyunsaturated fat, total carbohydrates, mono- and disaccharides, dietary fibre and potassium. The food lists generated by the MILP model have good performance in terms of length, coverage and R 2 (explained variance) of all nutrients. MILP-generated food lists were 32-40 % shorter than a benchmark food list, whereas their quality in terms of R 2 was similar to that of the benchmark. The results suggest that the MILP model makes the selection process faster, more standardised and transparent, and is especially helpful in coping with multiple nutrients. The complexity of the method does not increase with increasing number of nutrients. The generated food lists appear either shorter or provide more information than a food list generated without the MILP model.

Passive Optical Network (PON) deployments have recently been aiming to combine the capacity of metro and access networks in the last mile of the Internet service provisioning. Deployment of PONs by running fiber to the premises introduces the advantage of huge capacity but at the same time, it calls for a robust design in order to avoid long service outage durations in case of network failures where survivable network design is mostly limited to the deployment budget. In this paper, we propose three mixed integer linear programming (MILP) models for various survivability policies to deploy reliable long-reach PONs under the budget limitations. Each MILP model aims to place the ONUs in optimal locations so that the covered area is maximized while availability requirements of the users are satisfied within the deployment budget. We solve the MILP models under the uniform and heterogeneous availability requirement scenarios and show that service availability and coverage introduce a trade-off so as the coverage and deployment cost do. Two out of the three survivability policies can guarantee 99.99% service availability while the third one is able to guarantee 99.999% by running the proposed MILP models. However, the first two schemes are able to cover larger area when compared to the third scheme which is the most reliable protection policy.