- Conference Article
10
- 10.1109/ijcnn.2012.6252555
Composite kernel based SVM for hierarchical multi-label gene function classification
- Jun 01, 2012
- Benhui Chen + 2 more +2
This paper proposes a hierarchical multi-label classification method based on SVM with composite kernel for solving gene function prediction. The hierarchical multi-label classification problem is resolved into a set of binary classification tasks. A composite kernel based SVM (ck-SVM) is introduced to deal with the binary classification tasks. In estimation procedure of ck-SVM, a supervised clustering with over-sampling strategy is introduced for solving imbalance dataset learning problem and improve classification performance. Experimental results on benchmark datasets demonstrate that the proposed method improves the classification performance efficiently.
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