Advancements in deep structured learning based medical image interpretation

Along with the development of medical imaging technology, medical image analysis has become a crucial part of clinical diagnosis. However, traditional image analysis methods rely on manual feature extraction and expert evaluation, triggering problems such as low efficiency and lack of accuracy. Deep learning techniques, especially convolutional neural networks (CNNs), have made significant breakthroughs in medical image analysis in recent years. The aim of this paper is to study the application of deep learning in medical imaging, and explore the advantages and development potential in early disease diagnosis, image segmentation and feature extraction. This paper reviews the basic principles of deep learning and analyses the applicability of deep learning in medical imaging by combining the characteristics of medical imaging. Through systematic analysis of existing literature, this paper summarises the remarkable achievements of deep learning in processing, analysing and applying it to various medical images, such as Optical Coherence Tomography (OCT), Magnetic Resonance Imaging (MRI) and so on. It has been shown that deep learning methods can significantly improve the accuracy and efficiency of medical image processing and demonstrate performance due to traditional methods in tasks such as classification. However, how to improve the interpretability of models and the generalisability of clinical applications are still current research hotspots and challenges.

Breast cancer is the most prevalent cancer globally and presents a significant threat to human health. The low survival rate for advanced stages highlights the importance of early and accurate diagnosis. Pathology images, providing insights into cancer's cellular aggressiveness, are crucial for breast cancer diagnosis. Advances in deep learning have transformed automated medical image diagnosis. However, traditional deep learning methods, reliant on large labeled datasets, face challenges with the typically small size of medical image datasets. To overcome this, our study combines deep transfer learning (DTL) with convolutional neural networks(CNN). We utilize and enhance a ResNet50 model pretrained on a large dataset. Additionally, we apply four different deep transfer learning methods to feature extraction and classification of the BreakHis dataset, aiming to determine if breast cancer is benign or malignant. Ultimately, our system achieved the best average accuracy rates under four different magnifications: 98.57%, 96.83%, 97.76%, and 97.16%. These results demonstrate the accuracy and potential of deep transfer learning in classifying breast cancer histopathological images and its promising application in tumor prediction.

Deep learning has attracted great attention in the medical imaging community as a promising solution for automated, fast and accurate medical image analysis, which is mandatory for quality healthcare. Convolutional neural networks and its variants have become the most preferred and widely used deep learning models in medical image analysis. In this paper, concise overviews of the modern deep learning models applied in medical image analysis are provided and the key tasks performed by deep learning models, i.e. classification, segmentation, retrieval, detection, and registration are reviewed in detail. Some recent researches have shown that deep learning models can outperform medical experts in certain tasks. With the significant breakthroughs made by deep learning methods, it is expected that patients will soon be able to safely and conveniently interact with AI-based medical systems and such intelligent systems will actually improve patient healthcare. There are various complexities and challenges involved in deep learning-based medical image analysis, such as limited datasets. But researchers are actively working in this area to mitigate these challenges and further improve health care with AI.

The use of machine learning (ML) has been increasing rapidly in the medical imaging field, including computer-aided diagnosis (CAD), radiomics, and medical image analysis. Recently, an ML area called deep learning emerged in the computer vision field and became very popular in many fields. It started from an event in late 2012, when a deep-learning approach based on a convolutional neural network (CNN) won an overwhelming victory in the best-known worldwide computer vision competition, ImageNet Classification. Since then, researchers in virtually all fields, including medical imaging, have started actively participating in the explosively growing field of deep learning. In this paper, the area of deep learning in medical imaging is overviewed, including (1) what was changed in machine learning before and after the introduction of deep learning, (2) what is the source of the power of deep learning, (3) two major deep-learning models: a massive-training artificial neural network (MTANN) and a convolutional neural network (CNN), (4) similarities and differences between the two models, and (5) their applications to medical imaging. This review shows that ML with feature input (or feature-based ML) was dominant before the introduction of deep learning, and that the major and essential difference between ML before and after deep learning is the learning of image data directly without object segmentation or feature extraction; thus, it is the source of the power of deep learning, although the depth of the model is an important attribute. The class of ML with image input (or image-based ML) including deep learning has a long history, but recently gained popularity due to the use of the new terminology, deep learning. There are two major models in this class of ML in medical imaging, MTANN and CNN, which have similarities as well as several differences. In our experience, MTANNs were substantially more efficient in their development, had a higher performance, and required a lesser number of training cases than did CNNs. "Deep learning", or ML with image input, in medical imaging is an explosively growing, promising field. It is expected that ML with image input will be the mainstream area in the field of medical imaging in the next few decades.

Recent revolutionary advances in deep learning (DL) have fueled several breakthrough achievements in various complicated computer vision tasks. The remarkable successes and achievements started in 2012 when deep learning neural networks (DNNs) outperformed the shallow machine learning models on a number of significant benchmarks. Significant advances were made in computer vision by conducting very complex image interpretation tasks with outstanding accuracy. These achievements have shown great promise in a wide variety of fields, especially in medical image analysis by creating opportunities to diagnose and treat diseases earlier. In recent years, the application of the DNN for object localization has gained the attention of researchers due to its success over conventional methods, especially in object localization. As this has become a very broad and rapidly growing field, this study presents a short review of DNN implementation for medical images and validates its efficacy on benchmarks. This study presents the first review that focuses on object localization using the DNN in medical images. The key aim of this study was to summarize the recent studies based on the DNN for medical image localization and to highlight the research gaps that can provide worthwhile ideas to shape future research related to object localization tasks. It starts with an overview on the importance of medical image analysis and existing technology in this space. The discussion then proceeds to the dominant DNN utilized in the current literature. Finally, we conclude by discussing the challenges associated with the application of the DNN for medical image localization which can drive further studies in identifying potential future developments in the relevant field of study.

Machine learning techniques such as deep learning methods have produced promising results in medical images analysis. This work proposes a user-friendly system that utilizes deep learning techniques for detecting and diagnosing diseases using medical images. This includes the design of CAD-based project that can reduce human factor-related errors while performing manual screening of medical images. The system accepts medical images as input and performs segmentation of the images. Segmentation process analyzes and identifies the region of interest (ROI) of diseases from medical images. Analyzing and segmentation of medical images has assisted in the diagnosis and monitoring of some diseases. Diseases such as skin cancer, age-related fovea degeneration, diabetic retinopathy, glaucoma, hypertension, arteriosclerosis, and choroidal neovascularization can be effectively managed by the analysis of skin lesion and retinal vessels images. The proposed system was evaluated on diseases such as diabetic retinopathy from retina images and skin cancer from dermoscopic images.

Organ-on-a-chip (OOC) is a new type of biochip technology. Various types of OOC systems have been developed rapidly in the past decade and found important applications in drug screening and precision medicine. However, due to the complexity in the structure of both the chip-body itself and the engineered-tissue inside, the imaging and analysis of OOC have still been a big challenge for biomedical researchers. Considering that medical imaging is moving towards higher spatial and temporal resolution and has more applications in tissue engineering, this paper aims to review medical imaging methods, including CT, micro-CT, MRI, small animal MRI, and OCT, and introduces the application of 3D printing in tissue engineering and OOC in which medical imaging plays an important role. The achievements of medical imaging assisted tissue engineering are reviewed, and the potential applications of medical imaging in organoids and OOC are discussed. Moreover, artificial intelligence - especially deep learning - has demonstrated its excellence in the analysis of medical imaging; we will also present the application of artificial intelligence in the image analysis of 3D tissues, especially for organoids developed in novel OOC systems.

Deep learning methods have become popular among researchers in the field of fault detection. However, their performance depends on the availability of big datasets. To overcome this problem researchers started applying transfer learning to achieve good performance from small available datasets, by leveraging multiple prediction models over similar machines and working conditions. However, the influence of negative transfer limits their application. Negative transfer among prediction models increases when the environment and working conditions are changing continuously. To overcome the effect of negative transfer, we propose a novel deep transfer learning method, coined deep boosted transfer learning, for wind turbine gearbox fault detection that prevents negative transfer and only focuses on relevant information from the source machine. The proposed method is an instance-based deep transfer learning method that updates the weights of the source and the target machine training samples separately. The weights of different source training samples are gradually decreased to reduce the impact on the final model. The proposed method is verified by the Case Western Reserve University bearing and real field wind farm datasets. The results show that the proposed method ignores negative transfer and achieves higher accuracy compared to standard deep learning and deep transfer learning methods.

This review paper examines the current state of lung disease diagnosis based on deep learning (DL) methods. Lung diseases, such as Pneumonia, TB, Covid-19, and lung cancer, are significant causes of morbidity and mortality worldwide. Accurate and timely diagnosis of these diseases is essential for effective treatment and improved patient outcomes. DL methods, which utilize artificial neural networks to extract features from medical images automatically, have shown great promise in improving the accuracy and efficiency of lung disease diagnosis. This review discusses the various DL methods that have been developed for lung disease diagnosis, including convolutional neural networks (CNNs), deep neural networks (DNNs), and generative adversarial networks (GANs). The advantages and limitations of each method are discussed, along with the types of medical imaging techniques used, such as X-ray and computed tomography (CT). In addition, the review discusses the most commonly used performance metrics for evaluating the performance of DL for lung disease diagnosis: the area under the curve (AUC), sensitivity, specificity, F1-score, accuracy, precision, and the receiver operator characteristic curve (ROC). Moreover, the challenges and limitations of using DL for lung disease diagnosis, including the limited availability of annotated data, the variability in imaging techniques and disease presentation, and the interpretability and generalizability of DL models, are highlighted in this paper. Furthermore, strategies to overcome these challenges, such as transfer learning, data augmentation, and explainable AI, are also discussed. The review concludes with a call for further research to address the remaining challenges and realize DL's full potential for improving lung disease diagnosis and treatment.

Medical imaging is an indispensable tool in clinical diagnosis and therapeutic decision-making, encompassing a wide range of modalities such as radiography, ultrasound, CT, and MRI. With the rapid advancement of deep learning technologies, significant progress has been made in medical image analysis. However, existing deep learning methods are often limited by dataset size, which can lead to overfitting, while traditional approaches relying on hand-crafted features lack specificity and fail to fully capture complex pathological information. To address these challenges, we propose RadioGuide-DCN, an innovative radiomics-guided decorrelated classification network. Our method integrates radiomics features as prior information into deep neural networks and employs a feature decorrelation loss mechanism combined with an anti-attention feature fusion module to effectively reduce feature redundancy and enhance the model's capacity to capture both local details and global patterns. Specifically, we utilize a Kolmogorov-Arnold Network (KAN) classifier with learnable activation functions to further boost performance across various medical imaging datasets. Experimental results demonstrate that RadioGuide-DCN achieves an accuracy of 93.63% in BUSI image classification and consistently outperforms conventional radiomics and deep learning methods in multiple medical imaging classification tasks, significantly improving classification accuracy and AUC scores. Our study offers a novel paradigm for integrating deep learning with traditional imaging approaches and holds broad clinical application potential, particularly in tumor detection, image classification, and disease diagnosis.

Deep Learning has the potential to renovate healthcare; alternatively, extensive skill is vital to train such models. In medical imaging, a diagnosis with precision and speed is done through Artificial Intelligence (AI), which includes Deep Learning. When compared with healthcare professionals, the Deep Learning models achieved a similar level of diagnostic accuracy. As such, most of the diagnostic technique is systematic, as it has intelligent classification approaches with the computer-aided decision support systems. Deep Learning methods, such as Convolutional Neural Network (CNN), Deep Belief Network (DBN), and Recurrent Neural Network (RNN), support the classification. In recent studies, CNN has been found to be a vital technique for extracting valuable features from a medical dataset of images and may result in higher accuracy. Artificial intelligence (AI) in the form of Deep Learning (DL) and within the field of medical imaging has created remarkable developments in the classification of medical imaging datasets.

Brain tumors, a leading cause of mortality, necessitate accurate and timely detection for effective treatment. Recent advancements in deep learning and medical imaging have significantly enhanced the capability to identify and classify cancers. This extensive study focuses on three specific tumor types: glioma, meningioma, and pituitary tumors and explores the application of deep transfer learning methods for brain tumor classification utilizing convolutional neural networks (CNN). By analyzing MRI scans, the research assesses the performance of pretrained CNN models, including ResNet-50, Inception-v3, and VGG-16 in automating tumor prediction. The study employs performance metrics such as accuracy, precision, recall, and F1 scores to evaluate how effectively each model aids in early diagnosis and improves clinical decision-making.

Due to the complexity of medical images, traditional medical image classification methods have been unable to meet the actual application needs. In recent years, the rapid development of deep learning theory has provided a technical approach for solving medical image classification. However, deep learning has the following problems in the application of medical image classification. First, it is impossible to construct a deep learning model with excellent performance according to the characteristics of medical images. Second, the current deep learning network structure and training strategies are less adaptable to medical images. Therefore, this paper first introduces the visual attention mechanism into the deep learning model so that the information can be extracted more effectively according to the problem of medical images, and the reasoning is realized at a finer granularity. It can increase the interpretability of the model. Additionally, to solve the problem of matching the deep learning network structure and training strategy to medical images, this paper will construct a novel multiscale convolutional neural network model that can automatically extract high-level discriminative appearance features from the original image, and the loss function uses the Mahalanobis distance optimization model to obtain a better training strategy, which can improve the robust performance of the network model. The medical image classification task is completed by the above method. Based on the above ideas, this paper proposes a medical classification algorithm based on a visual attention mechanism-multiscale convolutional neural network. The lung nodules and breast cancer images were classified by the method in this paper. The experimental results show that the accuracy of medical image classification in this paper is not only higher than that of traditional machine learning methods but also improved compared with other deep learning methods, and the method has good stability and robustness.

A conversational agent (chatbot) is computer software capable of communicating with humans using natural language processing. The crucial part of building any chatbot is the development of conversation. Despite many developments in Natural Language Processing (NLP) and Artificial Intelligence (AI), creating a good chatbot model remains a significant challenge in this field even today. A conversational bot can be used for countless errands. In general, they need to understand the user's intent and deliver appropriate replies. This is a software program of a conversational interface that allows a user to converse in the same manner one would address a human. Hence, these are used in almost every customer communication platform, like social networks. At present, there are two basic models used in developing a chatbot. Generative based models and Retrieval based models. The recent advancements in deep learning and artificial intelligence, such as the end-to-end trainable neural networks have rapidly replaced earlier methods based on hand-written instructions and patterns or statistical methods. This paper proposes a new method of creating a chatbot using a deep neural learning method. In this method, a neural network with multiple layers is built to learn and process the data.

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