Human voices contain a significant number of sources of variability. This fact can result in speaker's intrinsic characteristics, such as gender, age, accent, and other extrinsic characteristics, such as the acoustic environment, severely interfering with the performance of different speech technology applications. Along the years, several proposals have been developed in the area of speech technologies to tackle the impact of these undesired sources of variability. There is clearly a need to build robust speech representations that avoid these undesired factors, which are one of the reasons for complexity when speech applications are developed. One of these approaches is domain adaptation which has been proposed to learn a mapping between different domains, reducing the gap that may exist between them. With the rapid advances in Deep Learning, new methods for robust speech representations are being proposed. The concept of adversarial learning necessitates the creation of an intermediate latent space representation, which is invariant to a specific domain. This method formulates a minimization-maximization problem, where a primary learning optimization task is combined with a secondary domain classification task, which is optimized to perform badly. The main objective of this Thesis is to contribute to the research on supervised adversarial learning within Deep Neural Networks, as a powerful way to obtain speech features discriminant to the application task, and invariant to undesired sources of variability. This goal was planned to attempt to solve the limitations of speech technologies in three different areas of application: i) the assessment of obstructive sleep apnea from speech, where the target is to model robust apnea-related representations by suppressing the undesirable effect of other patient characteristics, such age or obesity; ii) speech privacy preservation, by developing a state-of-the-art anonymization system to model speaker-invariant representations by removing personal identifiable information, such as gender or accent; and iii) automatic speech recognition to build robust speech representations invariant to challenging acoustic conditions in TV shows. The experimental results proved that adversarial learning contributes to improve the peri formance in the three analyzed speech applications: increasing the accuracy of the obstructive sleep apnea assessment after removing speaker's body mass index; obtaining high level of speech privacy and good intelligibility, being one of the best methods in the state-of-the art; and finally, achieving slight improvements in automatic speech recognition but yielding promising results to continue its exploration. Thus, the specific objectives of this Thesis can be considered fulfilled. Main contributions of this PhD Thesis resulted in several publications in Journals with JCR and peer-reviewed conferences. Three of them, each one related to the aforementioned speech applications, are advocated for the compendium presentation of this Thesis according to the requirements demanded by the Universidad Politécnica de Madrid. An additional, but no less significant, contribution is an in-depth review of the state-ofthe-art adversarial learning techniques, which leads us to study the evolution of this technique, helping us to determine that it is a competitive approach to develop domain-invariant features in speech applications. Asimismo, me gustaría agradecer a los revisores de esta tesis, su tiempo y predisposición, para mejorar la calidad de esta memoria, y por las valoraciones presentadas. Dr. Rubén San Segundo, Dra. Ascensión Gallardo, y Dr. Doroteo Torre, gracias. Mi agradecimiento a todos los miembros de Sigma Technologies y Tax Planning, especialmente al Dr. Daniel Tapias, quién apoyó el inicio de este camino dentro de la empresa. A Javier, eterno compañero, con el que hice los primeros pinitos en un congreso. A Richard, por su tiempo y ayuda revisando esta memoria escrita en su idioma natal. A Rafael, quien me dio la oportunidad de tutorizar su TFM y aprender juntos. Y a todos aquellos antiguos compañeros que se han quedado con un sitio de amigo/a. Siempre guardo una mención especial para mi amigo Fulgencio, un hermano, gracias por tu apoyo y tus consejos a lo largo de estos años. Gracias también a mis amigos David, Guille, Mario, Raúl, Ángel y Jorge, la mayoría de ellos han convertido mis viernes de regreso a Madrid, en una cita obligada. vii No pueden faltar los integrantes de la familia del "Alcobendas United": Marco, Isma, Robert, Nando, Diego, Rodri, Miguel, Jose, Raúl. Siempre dispuestos a repartir alegría en la jornada del domingo. A los de siempre: Álvaro, Rubén, Nacho y Sergio. Seguimos creciendo juntos. Y a María R., con quien la distancia no es un obstáculo para mantenerse actualizados. Tampoco quiero olvidarme de los que llegaron no hace mucho, pero han contribuido a que Tarragona se convierta en nuestra casa: Arantxa,
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