An efficient and automatic glioblastoma brain tumor detection using shift‐invariant shearlet transform and neural networks

In brain tumor diagnosis, clinicians integrate their medical knowledge and brain magnetic resonance imaging (MRI) scans to obtain the nature and pathological characteristics of brain tumors and to decide on treatment options. However, manually detecting and segmenting brain tumors in today's brain MRI, where a large number of MRI scans taken for each patient, is tedious and subjected to inter and intra observer detection and segmentation variability. As result a number of methods have been proposed in recent years to fill this gap, but still there is no commonly accepted automated technique by clinicians to be used in clinical floor due to accuracy and robustness issues. In our approach, an automatic brain tumor detection and segmentation framework that consists of techniques from skull stripping to detection and segmentation of brain tumors is proposed with fuzzy Hopfield neural network as its final tumor segmentation technique. Through preprocessing, image fusion and initial tumorous slice classification, the final hybrid intelligent fuzzy Hopfield neural network algorithm based tumor segmentation, and tumor region detection and extraction is achieved. The performance of the proposed framework is evaluated on various MR images including simulated and real, normal and tumorous. Quantitatively the method is validated against available ground truth using commonly used validation metrics. The final segmentation mean and standard deviation result in Jaccard similarity index, Dice similarity score, sensitivity and specificity are 0.8569+/-0.0896, 0.9186+/-0.0638, 0.9480+/-0.0402 and 0.9917+/-0.0387 respectively. Quantitative and qualitative segmentation result indicates the potential of the proposed framework.

Automatic detection and segmentation of brain tumors in 3D MR neuroimages can significantly aid early diagnosis, surgical planning, and follow-up assessment. However, due to diverse location and varying size, primary and metastatic tumors present substantial challenges for detection. We present a fully automatic, unsupervised algorithm that can detect single and multiple tumors from 3 to 28,079 mm <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">3</sup> in volume. Using 20 clinical 3D MR scans containing from 1 to 15 tumors per scan, the proposed approach achieves between 87.84% and 95.30% detection rate and an average end-to-end running time of under 3 minutes. In addition, 5 normal clinical 3D MR scans are evaluated quantitatively to demonstrate that the approach has the potential to discriminate between abnormal and normal brains.

A Review on Convolutional Neural Networks for Brain Tumor Segmentation: Methods, Datasets, Libraries, and Future Directions

In this paper, we present a new approach that allows the detection and segmentation of brain tumors automatically. The approach is based on covariance and geodesic distance. The detection of central coordinates of abnormal tissues is based on the covariance method. These coordinates are used to segment the brain tumor area using geodesic distance for T1 and T2 weighted magnetic resonance images (MRI). The ultimate objective is to retrieve the attributes of the tumor observed on the image to use them in the step of segmentation and classification. The present methods are tested on images of T1 and T2 weighted MR and have shown a better performance in the analysis of biomedical images.

In this work, we propose a fully automatic brain tumor and edema segmentation technique in brain magnetic resonance (MR) images. Different brain tissues are characterized using the novel texture features such as piece-wise triangular prism surface area (PTPSA), multi-fractional Brownian motion (mBm) and Gabor-like textons, along with regular intensity and intensity difference features. Classical Random Forest (RF) classifier is used to formulate the segmentation task as classification of these features in multi-modal MRIs. The segmentation performance is compared with other state-of-art works using a publicly available dataset known as Brain Tumor Segmentation (BRATS) 2012 [1]. Quantitative evaluation is done using the online evaluation tool from Kitware/MIDAS website [2]. The results show that our segmentation performance is more consistent and, on the average, outperforms other state-of-the art works in both training and challenge cases in the BRATS competition.

This paper presents an efficient and accurate automated system based on the hybrid XGBoost with Random forest (XGBRF) ensemble model in order to classify the Glioma (type of mostly diagnosed brain tumor) into low grade and high grade Glioma. In this approach initially global thresholding is employed on various MRI sequence and their fusion combinations in order to perform the accurate segmentation. Then uses a proposed Enhanced wavelet binary pattern run length matrix method (EWBPRL) for textural features extraction from the region of interest or segmented Glioma tumor region. This proposed feature extraction method is based on the Discrete wavelet transform (DWT), Local Binary pattern (LBP) and Gray level run length Matrix (GLRLM) methods to extract texture features from the segmented region. Some morphological features are also computed from the segmented region along the textural features. Finally both these extracted features are employed in order to train a hybrid XGBoost with Random forest ensemble model for the first time. The proposed automated system apart from accurately detecting and segmenting the tumors region from the fused MRI sequences, also tends to determine the grading of Glioma in terms of severity. The proposed system is evaluated on the large size balance local dataset and as well as on the popular global datasets like BRATS 2013 and BRATS 2015. This approach offers an encouraging accuracy of 99.25% on the local dataset with the fusion of T1C+T2+Flair MRI sequence as compare to 96.75% accuracy, which is achieved utilizing the fusion of T1+T1C+T2+Flair MRI sequence.

Intraoperative ultrasound (iUS) is increasingly used in pediatric brain tumor surgery. However, accurate tumor tissue identification and localization within the patient with iUS remains challenging. Automatic tumor segmentation may overcome these difficulties by providing quicker, more consistent, and reliable image analysis. This study evaluated the feasibility of automatic 3-dimensional segmentation of pediatric brain tumors using navigated iUS. A retrospective analysis was conducted on 109 navigated iUS acquisitions from 60 pediatric patients who underwent neurosurgical tumor resection. 3-dimensional nnU-Net was trained on 79 preresectional iUS acquisitions with corresponding tumor segmentations. Evaluation was performed on 30 iUS acquisitions against segmentations validated by 2 neurosurgeons. Performance benchmarks were set at a minimum Dice Similarity Coefficient (DSC) of 0.85 and a maximum mean surface distance and 95th percentile Hausdorff distance of 5 mm. The trained algorithm predicted tumor segmentations for all acquisitions in the test set, which met the predefined benchmark values with a median DSC of 0.89 (IQR: 0.13), a median mean surface distance of 1.1 mm (IQR: 1.0 mm), and a median 95th percentile Hausdorff distance of 5.6 mm (IQR: 3.5 mm). The lowest quartile of DSC values consisted of 5 patients, including craniopharyngiomas (n = 3) and high-grade gliomas (n = 2). Oversegmentation of the lateral ventricle as tumor was observed in 2 patients. In 1 high-grade glioma case, edema was misclassified as tumor because of unclear tumor boundaries. This study demonstrates that automatic segmentation of pediatric brain tumors using navigated iUS is feasible and achieved high performance in most cases, with few outliers that showed moderate performance in tumor prediction. Future efforts will focus on real-time segmentation of residual tumor tissue during tumor resection. Ultimately, real-time visualization of automatically segmented tumors in 3 dimensions could improve intraoperative navigation and support neurosurgical decision making.

An automatic segmentation of brain tumors from medical images is significant for diagnosis and treatment planning. Magnetic resonance imaging (MRI) is widely used by surgeons, radiologists, and medical specialists for brain segmentation. To enhance the reliability and security of the segmentation process, this study introduces a blockchain‐based Recursive Residual Blocks and Pyramid Pooling Segmentation Network (RP‐Segnet) for brain tumor segmentation using MRI. In the proposed framework, blockchain technology is employed to ensure the integrity and traceability of the parameters of the model by encrypting and verifying layer‐specific data, such as weights and biases. This prevents unauthorized tampering and enables secure handling of model data, thereby supporting robust and trustworthy segmentation. Initially, input MRI is acquired from the dataset and is transferred to the preprocessing step, wherein the unwanted images are eliminated by employing Gaussian filtering. Once the preprocessing is completed, the brain image is transferred to the brain tumor segmentation module, which separates the tumor region from the background of the tumor image, which is performed using the proposed RP‐Segnet. The RP‐Segnet is designed by the formation of Recursive residual blocks and a Pyramid pooling Network (RP‐Net) and Segmentation Network (SegNet). Moreover, the efficacy of the proposed RP‐Segnet for brain tumor segmentation is determined based on evaluation measures, such as segmentation accuracy, dice coefficient, and Jaccard similarity, and it has attained maximal values of 92.04%, 95.07%, and 95.03%.

Brain tumors are considered as most fatal cancers. To reduce the risk of death, early identification of the disease is required. One of the best available methods to evaluate brain tumors is Magnetic resonance Images (MRI). Brain tumor detection and segmentation are tough as brain tumors may vary in size, shape, and location. That makes manual detection of brain tumors by exploring MRI a tedious job for radiologists and doctors’. So an automated brain tumor detection and segmentation is required. This work suggests a Region-based Convolution Neural Network (RCNN) approach for automated brain tumor identification and segmentation using MR images, which helps solve the difficulties of brain tumor identification efficiently and accurately. Our methodology is based on the accurate and efficient selection of tumorous areas. That reduces computational complexity and time. We have validated the designed experimental setup on a standard dataset, BraTS 2020. We used binary evaluation matrices based on Dice Similarity Coefficient (DSC) and Mean Average Precision (mAP). The segmentation results are compared with state-of-the-art methodologies to demonstrate the effectiveness of the proposed method. The suggested approach attained an average DSC of 0.92 and mAP 0.92 for 10 patients, while on the whole dataset, the scores are DSC 0.89 and mAP 0.90. The following results clearly show the performance efficiency of the proposed methodology.

The segmentation of MRI brain tumors utilizes computer technology to segment and label tumors and normal tissues automatically on multimodal brain images, which plays an important role in disease diagnosis, treatment planning, and surgical navigation. We propose a solution using gray-level co-occurrence matrix (GLCM) texture and an ensemble Support Vector Machine (SVM) structure.This manuscript per the authors focus on the effects of GLCM texture on brain tumor segmentation. The result is different from the application of the GLCM texture in other types of image processing.The experimental material was a dataset called BraTs2015. The segmented five different labels are normal brain, necrosis, edema, non-enhancing tumor, and enhancing tumor. The proposed model was verified with the Dice coefficient. The result demonstrated that this method has a better capacity and higher segmentation accuracy with a low computation cost.

CLCU-Net: Cross-level connected U-shaped network with selective feature aggregation attention module for brain tumor segmentation

A Validation Framework for Brain Tumor Segmentation

The ferrite magnetic tiles are widely used in industry field. At present, the defects detection in ferrite magnetic tile surfaces is done by manual work. In order to improve the defects detection efficiency and prevent missed and false detection, an automatic detection system applied to the magnetic tiles non-destructive detection was proposed based on computer vision. A suit of the automatic defects detection equipment used for magnetic tile surfaces was designed so that we can adjust the position and angle of the lightings and cameras programmatically to meet the requirement of different location for different kinds of magnetic tiles. To solve the problem of automatically detect defects from magnetic tile images which are with dark colors and low contrasts, a new hybrid algorithm which combines nonsubsampled Contourlet transform and Laws texture feature measurement was proposed to eliminate the influence of the grinding textures and extract defects. In this methodology the original image was first decomposed by nonsubsampled Contourlet transform, the characteristics of the decomposition coefficients are analyzed by Laws texture feature measurement. Then according to the texture energies of the restructured image, a segmentation threshold was determined to reset the decomposition coefficients. Finally the image was reconstructed with the reconstruction coefficients, the grinding textures were eliminated and defects were obtained by Canny operator. The experimental results show that based on the proposed method, the grinding textures can be eliminated effectively, the defects can be extracted accurately, and the accuracy rate of extraction defects can achieve 93.57%. The automatic detection system can provide an effective solution to magnetic tile defects detection industry.

Structural magnetic resonance imaging (MRI) has been widely utilized for analysis and diagnosis of brain diseases. Automatic segmentation of brain tumors is a challenging task for computer-aided diagnosis due to low-tissue contrast in the tumor subregions. To overcome this, we devise a novel pixel-wise segmentation framework through a convolutional 3D to 2D MR patch conversion model to predict class labels of the central pixel in the input sliding patches. Precisely, we first extract 3D patches from each modality to calibrate slices through the squeeze and excitation (SE) block. Then, the output of the SE block is fed directly into subsequent bottleneck layers to reduce the number of channels. Finally, the calibrated 2D slices are concatenated to obtain multimodal features through a 2D convolutional neural network (CNN) for prediction of the central pixel. In our architecture, both local inter-slice and global intra-slice features are jointly exploited to predict class label of the central voxel in a given patch through the 2D CNN classifier. We implicitly apply all modalities through trainable parameters to assign weights to the contributions of each sequence for segmentation. Experimental results on the segmentation of brain tumors in multimodal MRI scans (BraTS’19) demonstrate that our proposed method can efficiently segment the tumor regions.

Brain tumors are one of the deadliest cancers in the world. Researchers have conducted a lot of research work on brain tumor segmentation with good performance due to the rapid development of deep learning for assisting doctors in diagnosis and treatment. However, most of these methods cannot fully combine multiple feature information and their performances need to be improved. This study developed a novel network fusing local features representing detailed information, global features representing global information, and multi-scale features enhancing the model’s robustness to fully extract the features of brain tumors and proposed a novel axial-deformable attention module for modeling global information to improve the performance of brain tumor segmentation to assist clinicians in the automatic segmentation of brain tumors. Moreover, positional embeddings were used to make the network training faster and improve the method’s performance. Six metrics were used to evaluate the proposed method on the BraTS2018 dataset. Outstanding performance was obtained with Dice score, mean Intersection over Union, precision, recall, params, and inference time of 0.8735, 0.7756, 0.9477, 0.8769, 69.02 M, and 15.66 millisecond, respectively, for the whole tumor. Extensive experiments demonstrated that the proposed network obtained excellent performance and was helpful in providing supplementary advice to the clinicians.