An LSTM Encoder-Decoder Approach for Unsupervised Online Anomaly Detection in Machine Learning Packages for Streaming Data

The aging and multimorbid population and health personnel shortages pose a substantial burden on primary health care. While predictive machine learning (ML) algorithms have the potential to address these challenges, concerns include transparency and insufficient reporting of model validation and effectiveness of the implementation in the clinical workflow. To systematically identify predictive ML algorithms implemented in primary care from peer-reviewed literature and US Food and Drug Administration (FDA) and Conformité Européene (CE) registration databases and to ascertain the public availability of evidence, including peer-reviewed literature, gray literature, and technical reports across the artificial intelligence (AI) life cycle. PubMed, Embase, Web of Science, Cochrane Library, Emcare, Academic Search Premier, IEEE Xplore, ACM Digital Library, MathSciNet, AAAI.org (Association for the Advancement of Artificial Intelligence), arXiv, Epistemonikos, PsycINFO, and Google Scholar were searched for studies published between January 2000 and July 2023, with search terms that were related to AI, primary care, and implementation. The search extended to CE-marked or FDA-approved predictive ML algorithms obtained from relevant registration databases. Three reviewers gathered subsequent evidence involving strategies such as product searches, exploration of references, manufacturer website visits, and direct inquiries to authors and product owners. The extent to which the evidence for each predictive ML algorithm aligned with the Dutch AI predictive algorithm (AIPA) guideline requirements was assessed per AI life cycle phase, producing evidence availability scores. The systematic search identified 43 predictive ML algorithms, of which 25 were commercially available and CE-marked or FDA-approved. The predictive ML algorithms spanned multiple clinical domains, but most (27 [63%]) focused on cardiovascular diseases and diabetes. Most (35 [81%]) were published within the past 5 years. The availability of evidence varied across different phases of the predictive ML algorithm life cycle, with evidence being reported the least for phase 1 (preparation) and phase 5 (impact assessment) (19% and 30%, respectively). Twelve (28%) predictive ML algorithms achieved approximately half of their maximum individual evidence availability score. Overall, predictive ML algorithms from peer-reviewed literature showed higher evidence availability compared with those from FDA-approved or CE-marked databases (45% vs 29%). The findings indicate an urgent need to improve the availability of evidence regarding the predictive ML algorithms' quality criteria. Adopting the Dutch AIPA guideline could facilitate transparent and consistent reporting of the quality criteria that could foster trust among end users and facilitating large-scale implementation.

Slope stability prediction using integrated metaheuristic and machine learning approaches: A comparative study

The purpose of this analysis is to assess the use of machine learning (ML) algorithms in the prediction of postoperative outcomes, including complications, recurrence, and death in transsphenoidal surgery. Following Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines, we systematically reviewed all papers that used at least one ML algorithm to predict outcomes after transsphenoidal surgery. We searched Scopus, PubMed, and Web of Science databases for studies published prior to May 12, 2021. We identified 13 studies enrolling 5,048 patients. We extracted the general characteristics of each study; the sensitivity, specificity, area under the curve (AUC) of the ML models developed as well as the features identified as important by the ML models. We identified 12 studies with 5,048 patients that included ML algorithms for adenomas, three with 1807 patients specifically for acromegaly, and five with 2105 patients specifically for Cushing's disease. Nearly all were single-institution studies. The studies used a heterogeneous mix of ML algorithms and features to build predictive models. All papers reported an AUC greater than 0.7, which indicates clinical utility. ML algorithms have the potential to predict postoperative outcomes of transsphenoidal surgery and can improve patient care. Ensemble algorithms and neural networks were often top performers when compared with other ML algorithms. Biochemical and preoperative features were most likely to be selected as important by ML models. Inexplicability remains a challenge, but algorithms such as local interpretable model–agnostic explanation or Shapley value can increase explainability of ML algorithms. Our analysis shows that ML algorithms have the potential to greatly assist surgeons in clinical decision making.

BackgroundDespite the interest in machine learning (ML) algorithms for analyzing real-world data (RWD) in healthcare, the use of ML in predicting time-to-event data, a common scenario in clinical practice, is less explored. ML models are capable of algorithmically learning from large, complex datasets and can offer advantages in predicting time-to-event data. We reviewed the recent applications of ML for survival analysis using RWD in healthcare.MethodsPUBMED and EMBASE were searched from database inception through March 2023 to identify peer-reviewed English-language studies of ML models for predicting time-to-event outcomes using the RWD. Two reviewers extracted information on the data source, patient population, survival outcome, ML algorithms, and the Area Under the Curve (AUC).ResultsOf 257 citations, 28 publications were included. Random survival forests (N = 16, 57%) and neural networks (N = 11, 39%) were the most popular ML algorithms. There was variability across AUC for these ML models (median 0.789, range 0.6–0.950). ML algorithms were predominately considered for predicting overall survival in oncology (N = 12, 43%). ML survival models were often used to predict disease prognosis or clinical events (N = 27, 96%) in the oncology, while less were used for treatment outcomes (N = 1, 4%).ConclusionsThe ML algorithms, random survival forests and neural networks, are mainly used for RWD to predict survival outcomes such as disease prognosis or clinical events in the oncology. This review shows that more opportunities remain to apply these ML algorithms to inform treatment decision-making in clinical practice. More methodological work is also needed to ensure the utility and applicability of ML models in survival outcomes.

Event detection has long been the domain of physical sensors operating in a static dataset assumption. The prevalence of social media and web access has led to the emergence of social, or human sensors who report on events globally. This warrants development of event detectors that can take advantage of the truly dense and high spatial and temporal resolution data provided by more than 3 billion social users. The phenomenon of concept drift, which causes terms and signals associated with a topic to change over time, renders static machine learning ineffective. Towards this end, we present an application for physical event detection on social sensors that improves traditional physical event detection with concept drift adaptation. Our approach continuously updates its machine learning classifiers automatically, without the need for human intervention. It integrates data from heterogeneous sources and is designed to handle weak-signal events (landslides, wildfires) with around ten posts per event in addition to large-signal events (hurricanes, earthquakes) with hundreds of thousands of posts per event. We demonstrate a landslide detector on our application that detects almost 350% more land-slides compared to static approaches. Our application has high performance: using classifiers trained in 2014, achieving event detection accuracy of 0.988, compared to 0.762 for static approaches.

The integration of machine learning (ML) algorithms into audit processes represents a significant advancement in the field of auditing, offering substantial benefits in terms of efficiency, accuracy, and risk management. This review examines the transformative potential of ML in auditing, highlighting its key benefits and the challenges that must be addressed to fully leverage its capabilities. Machine learning algorithms, with their ability to analyze large datasets and identify patterns, enhance the accuracy and thoroughness of audits. Traditional auditing methods often rely on sampling and manual checks, which can miss anomalies and fraudulent activities. In contrast, ML algorithms can process entire datasets, uncovering subtle patterns and irregularities that may indicate fraud or errors. This comprehensive analysis reduces the risk of oversight and improves the reliability of audit findings. One of the primary benefits of ML in auditing is its capacity for anomaly detection. ML models can be trained on historical data to understand normal financial behavior and flag deviations that might signify irregularities. This ability to detect anomalies in real-time enables auditors to identify potential issues promptly, reducing the time lag between occurrence and detection of fraud. Predictive analytics, powered by ML, further enhances audit processes by forecasting future risks based on historical data. This proactive approach allows auditors to anticipate and mitigate risks before they materialize, contributing to more robust risk management strategies. Despite these advantages, integrating ML into audit processes presents several challenges. Ensuring data quality and integrity is crucial, as ML algorithms are only as good as the data they analyze. Poor-quality data can lead to inaccurate predictions and conclusions. Additionally, the "black box" nature of some ML algorithms can pose transparency issues, making it difficult for auditors to explain how specific conclusions were reached, which is critical for stakeholder trust and regulatory compliance. Another significant challenge is the potential for algorithmic bias. ML models can inadvertently perpetuate existing biases in the data, leading to unfair or skewed audit outcomes. Continuous monitoring and validation of ML algorithms are necessary to detect and mitigate such biases. In conclusion, while integrating machine learning algorithms into audit processes offers substantial benefits in terms of accuracy, efficiency, and risk management, it also necessitates careful attention to data quality, transparency, and bias mitigation. Addressing these challenges is essential to fully realize the potential of ML in enhancing audit practices. Keywords: Benefits, Challenges, Audit Processes, Algorithms, ML.

This study presents a comparative analysis of the classification performance of facial and emotion recognition systems using Machine Learning (ML) and Deep Learning (DL) algorithms. The primary objective of this work is to evaluate the applicability of emotion recognition in fields such as psychotherapy and crime analysis, using the FER-2013 dataset.The study was conducted with ML algorithms such as Support Vector Machines (SVM), Random Forest (RF), K-Nearest Neighbor (KNN), Decision Trees, and Gradient Boosting, as well as the DL algorithm, Convolutional Neural Network (CNN). Supported by the application of feature selection, preprocessing, and feature extraction techniques, the model’s performance was measured using standard metrics such as accuracy, precision, F1-score, and AUC-ROC.The experimental results showed that the highest classification accuracy (46.61%) was achieved with the CNN model. While the ML models generally offered lower accuracy, they provided advantages in terms of computational efficiency in specific scenarios.This study aims to contribute to the literature by providing a comparative analysis of ML and DL algorithms and by highlighting the effect of data preprocessing on performance. The findings set targets for future work, such as real-time system integration and hybrid model development.

In the actual panorama of machine learning (ML) algorithms, the issue of the real-time information extraction/classification/manipulation/analysis of data streams (DS) is acquiring an ever-growing relevance. They arrive generally at high speed and always require an unsupervised real-time analysis for individuating long-range and higher order correlations among data that are continuously changing over time (phase transitions). This emphasizes the infinitary character of the issue, i.e., the continuous change of the signifying number of degrees of freedom characterizing the statistical representation function, challenging the classical ML algorithms, both in their classical and quantum versions, as far as all are based on the (stochastic) search for the global minimum of some cost/energy function. The physical analogue must be studied in the realm of quantum field theory (QFT) for dissipative systems as biological and neural systems, which are able to map between different phases of quantum fields, using the formalism of the Bogoliubov transform (BT). By applying the BT in a reversed way, on the system-thermal bath energetically balanced states, it is possible to define the powerful computational tool of the “doubling of the degrees of freedom” (DDF), making the choice of the signifying finite number of the degrees of freedom dynamic and then automatic, so to suggest a different class of unsupervised ML algorithms for solving the DS issue.

The expansion of electronic payments in the retail sector has been accompanied by an increase in advanced payment frauds. Traditional rule based legacy static fraud detection methods, in most cases, proved inadequate to address dynamically changing and constantly evolving fraudster practices. This paper discusses an efficient real time fraud detection system through a combination of Machine Learning (ML) algorithms and real time data stream processing technology. The study is helpful in the sense that it has a constructed synthetic transaction data set which was specially designed and built to be utilized for the very specific purpose of simulating real retail payment scenarios. The data have 489 samples with columns of transaction amount, merchant category, time of day, and frequency of transactions. We test and use a subset of the ML algorithms, like Random Forest and Gradient Boosting, to identify fraud effectively with very low latency. The solution takes consumption transaction as an Apache Kafka stream simulated, real time feature creation, and scoring of transactions using trained ML models. It depicts how ensemble methods, of which Gradient Boosting is a fair example, are more precise in recall and accuracy and minimize false negatives and false positives to a significant degree. This research acknowledges the prospect of a streaming paradigm and sophisticated ML in developing adaptive and real time fraud detection systems of high value addition to the security framework of modern retail payment systems.

Satellite-based aerosol optical property retrieval over land, especially size-related parameters, is challenging. This study proposed a novel two-stage machine learning (ML) algorithm for retrieving aerosol optical depth (AOD), Ångström exponent (AE), fine mode fraction (FMF), and fine mode AOD (FAOD)) over land using MODIS observed reflectance. The new ML algorithm consists of three steps: (1) first, all samples extracted from AERONET measurements were used to train the ML model, (2) then, to reduce the extreme estimation bias of the model, divided low-value and high-value samples were used to train low-value and high-value ML models, respectively, and (3) finally, the three ML models were integrated into the final retrieval based on the weight interpolation. Independent site network validation results show that the new ML algorithm has a Pearson correlation coefficient (R) of 0.894 (0.638, 0.661, 0.865) and root mean square error (RMSE) of 0.146 (0.258, 0.245, 0.153) for the AOD (AE, FMF, FAOD) retrieval, which significantly outperforms the validation metrics of MODIS operational products, with AOD (AE, FMF, FAOD) RMSE of 0.130-0.156 (0.536-0.569, 0.313, 0.191). The inter-comparison of aerosol products shows that the spatial patterns of AOD, AE, FMF, and FAOD of the new ML algorithm are in good agreement with those of the MODIS and POLDER products. These results illustrate that the new ML algorithm has good performance and transferability and indicate the ability of ML methods to be applied to multispectral instruments (such as MODIS) to retrieve multiple aerosol properties.

Machine learning (ML) algorithms seek to extract the most beneficial information out of the raw data. As mentioned in previous chapters, preprocess data preparation actions might be needed in order to make the data set ready to be fed into the ML algorithms. ML algorithms have gotten the attention of researchers all over the world during the last few decades. In traditional algorithms, the analyst had to define the rules, which was not always accessible or easily possible, in order to obtain the output. ML algorithms develop the models or rules based on the training data set which include input and output data points. ML algorithms try to understand more beneficial information regarding the system based on the training data set. The built model can be tested using the verification data set which does not have any overlap with the training sets. If the model acquires the acceptable performance measures, it can be applied for other cases to perform the prediction process. It should be considered that ML algorithms are not supposed to do the magic. Indeed, they are supposed to explore and analyze the training data, which the human brain is not able to handle that, to develop a predictive model in which its performance is acceptable for the verification data set. Predictive models should be generalized which means performing satisfactorily for both training and verifying data sets.

A machine learning (ML) algorithm for automatic segmentation of intravascular ultrasound was previously validated. It has the potential to improve efficiency, accuracy and precision of coronary vessel segmentation compared to manual segmentation by interventional cardiology experts. The aim of this study is to compare the performance of human readers to the machine and against the readings from a Core Laboratory. This is a post-hoc, cross-sectional analysis of the IBIS-4 study. Forty frames were randomly selected and analyzed by 10 readers of varying expertise two separate times, 1week apart. Their measurements of lumen, vessel, plaque areas, and plaque burden were performed in an offline software. Among humans, the intra-observer variability was not statistically significant. For the total 80 frames, inter-observer variability between human readers, the ML algorithm and Core Laboratory for lumen area, vessel area, plaque area and plaque burden were not statistically different. For lumen area, however, relative differences between the human readers and the Core Lab ranged from 0.26 to 12.61%. For vessel area, they ranged from 1.25 to 9.54%. Efficiency between the ML algorithm and the readers differed notably. Humans spent 47min on average to complete the analyses, while the ML algorithm took on average less than 1min. The overall lumen, vessel and plaque means analyzed by humans and the proposed ML algorithm are similar to those of the Core Lab. Machines, however, are more time efficient. It is warranted to consider use of the ML algorithm in clinical practice.

Aim: Machine learning (ML) and deep learning (DL) predictive models have been employed widely in clinical settings. Their potential support and aid to the clinician of providing an objective measure that can be shared among different centers enables the possibility of building more robust multicentric studies. This study aimed to propose a user-friendly and low-cost tool for COVID-19 mortality prediction using both an ML and a DL approach. Method: We enrolled 2348 patients from several hospitals in the Province of Reggio Emilia. Overall, 19 clinical features were provided by the Radiology Units of Azienda USL-IRCCS of Reggio Emilia, and 5892 radiomic features were extracted from each COVID-19 patient’s high-resolution computed tomography. We built and trained two classifiers to predict COVID-19 mortality: a machine learning algorithm, or support vector machine (SVM), and a deep learning model, or feedforward neural network (FNN). In order to evaluate the impact of the different feature sets on the final performance of the classifiers, we repeated the training session three times, first using only clinical features, then employing only radiomic features, and finally combining both information. Results: We obtained similar performances for both the machine learning and deep learning algorithms, with the best area under the receiver operating characteristic (ROC) curve, or AUC, obtained exploiting both clinical and radiomic information: 0.803 for the machine learning model and 0.864 for the deep learning model. Conclusions: Our work, performed on large and heterogeneous datasets (i.e., data from different CT scanners), confirms the results obtained in the recent literature. Such algorithms have the potential to be included in a clinical practice framework since they can not only be applied to COVID-19 mortality prediction but also to other classification problems such as diabetic prediction, asthma prediction, and cancer metastases prediction. Our study proves that the lesion’s inhomogeneity depicted by radiomic features combined with clinical information is relevant for COVID-19 mortality prediction.

The rapid growth of the Internet and information technologies and also the diminution of the price of hardware components like wireless sensors leads to the fast growth in Wireless Sensor Network (WSN). The WSN is a bunch/group of sensors that are located across the area, in order to monitor and determine environmental conditions such as temperature, humidity, vibrations, wind, water levels, pollution levels. WSNs are susceptible to major attacks like Denial of Service (DOS), Wormhole attack, Sinkhole attack, etc. The main threat to the WSN is because of the broadcast nature of the nodes in the network. Therefore, the security of WSNs is the essential part that must be done. Hence, to overcome these problems or threats, we are trying to detect it using AI technology. With the expanding fields of Machine Learning and Deep Learning, we can apply various algorithms in order to classify different types of attacks. Once we detect the attack properly, we can prevent it accordingly. We are using WSN-DS. It has 4 classes of attacks which are Grayhole, Blackhole, TDMA(Scheduling), and Flooding which comes under the category of DOS attacks. In this chapter, we have analysed and compared the accuracies of 5 main machine learning classification algorithms. Also, we have analysed the 1 deep learning algorithm. The ANN (Artificial Neural Network) and 5 machine learning algorithms have been trained on the dataset. Furthermore, we have used K-fold cross-validation to get even more accurate predictions. After analysis of these algorithms, we came to the point that, the Machine Learning algorithms like Random Forest, Support Vector Machines and Deep Learning algorithm, namely, Artificial Neural Network can help us for detecting intrusions in the system or network. This will help researchers in designing their own machine learning model on top of our suggested model.

Effect of High-Intensity Statin Therapy on Atherosclerosis (IBIS-4): Manual Versus Automated Methods of IVUS Analysis