Let u,v be solutions on an interval I of linear differential equations (LDEs) P=0 , Q=0 , respectively. We obtain a lower bound on the approximation of v by u in terms of bounds on the coefficients of LDE Si=0 (for several i ), satisfied by the i th derivative of v and by the i th derivative of a basis of the LDE P=0 . One could view this result as a differential analog of the Liouville theorem which states that two different algebraic numbers are well separated if they satisfy algebraic equations with small enough integer coefficients. Unlike the algebraic situation, in the differential setting, in order to bound from below the difference |u-v| , we need to involve not only the coefficients of P,Q themselves, but also those of Si .