Aquila: A Hierarchically Aligned Vision-Language Model for Enhanced Remote Sensing Image Comprehension

This chapter introduces essential systems and tools for leveraging various natural language processing (NLP) tasks and large language models (LLMs) in qualitative analysis, emphasizing accessibility for noncoders. It begins with an overview of the Python programming language and introduces tools such as the Pandas library, integrated development environments (IDEs), Jupyter notebooks, and application programming interfaces (APIs) for accessing LLMs. A second section provides a hands-on guide for setting up a computer environment, with step-by-step code examples designed to familiarize readers with NLP libraries and LLMs. It emphasizes the acquisition of programming skills to better adapt and utilize LLM capabilities for qualitative data analysis while providing multiple resources for further learning.

A novel prompting method for few-shot NER via LLMs

Work orders, equipment information, technical records and best practices documents contain within them a wealth of insights related to Equipment Maintenance which can be unlocked with Natural Language Processing tasks like classification, clustering, named entity recognition or part of speech tagging. But obtaining large enough labelled data sets in Equipment Maintenance domain manually is prohibitive and very expensive. This lack of labeled Equipment Maintenance data can be overcome with Large Language Models (LLMs) such as GPT-3, BERT that are pretrained transformer networks, considered state-of-the-art when it comes to Natural Language Processing (NLP) tasks. However, the vocabulary understood by these LLMs are mostly from English Language and need to be fine-tuned to understand industry and organization specific vocabulary and acronyms. This paper explores the potential of a domain specific LLM model for oil and gas industries. Data that are of good quality and that provide a comprehensive overview of industry are collected. This corpus of text contains documents like work orders, equipment data and technical documents. A custom tokenizer is trained on this data to identify domain specific terminology. A comparative study is done with other off-the-shelf tokenizers: BERT and RoBERTa, to compare the effectiveness of the tokenization. With millions of work orders and equipment documents, training pipelines had to parallelized so that training can occur on multiple GPUs. A comprehensive study of multiple training methods is done in this paper. Model and tokenizer developed were packaged and archived to be consumed in machine learning pipelines to specific use-cases across the organization. For an organization adopting digital transformation, the availability of an organization specific LLM is an enabler to extract insights from millions of documents containing free text. The applicability of such models spans across multiple disciplines like Maintenance, Reliability, Safety etc. and streamlines the development of highly accurate and robust text analytics.

BackgroundA large language model (LLM) is a machine learning model inferred from text data that captures subtle patterns of language use in context. Modern LLMs are based on neural network architectures that incorporate transformer methods. They allow the model to relate words together through attention to multiple words in a text sequence. LLMs have been shown to be highly effective for a range of tasks in natural language processing (NLP), including classification and information extraction tasks and generative applications.ObjectiveThe aim of this adapted Delphi study was to collect researchers’ opinions on how LLMs might influence health care and on the strengths, weaknesses, opportunities, and threats of LLM use in health care.MethodsWe invited researchers in the fields of health informatics, nursing informatics, and medical NLP to share their opinions on LLM use in health care. We started the first round with open questions based on our strengths, weaknesses, opportunities, and threats framework. In the second and third round, the participants scored these items.ResultsThe first, second, and third rounds had 28, 23, and 21 participants, respectively. Almost all participants (26/28, 93% in round 1 and 20/21, 95% in round 3) were affiliated with academic institutions. Agreement was reached on 103 items related to use cases, benefits, risks, reliability, adoption aspects, and the future of LLMs in health care. Participants offered several use cases, including supporting clinical tasks, documentation tasks, and medical research and education, and agreed that LLM-based systems will act as health assistants for patient education. The agreed-upon benefits included increased efficiency in data handling and extraction, improved automation of processes, improved quality of health care services and overall health outcomes, provision of personalized care, accelerated diagnosis and treatment processes, and improved interaction between patients and health care professionals. In total, 5 risks to health care in general were identified: cybersecurity breaches, the potential for patient misinformation, ethical concerns, the likelihood of biased decision-making, and the risk associated with inaccurate communication. Overconfidence in LLM-based systems was recognized as a risk to the medical profession. The 6 agreed-upon privacy risks included the use of unregulated cloud services that compromise data security, exposure of sensitive patient data, breaches of confidentiality, fraudulent use of information, vulnerabilities in data storage and communication, and inappropriate access or use of patient data.ConclusionsFuture research related to LLMs should not only focus on testing their possibilities for NLP-related tasks but also consider the workflows the models could contribute to and the requirements regarding quality, integration, and regulations needed for successful implementation in practice.

Generative large language models (LLMs) are a subset of transformers-based neural network architecture models. LLMs have successfully leveraged a combination of an increased number of parameters, improvements in computational efficiency, and large pre-training datasets to perform a wide spectrum of natural language processing (NLP) tasks. Using a few examples (few-shot) or no examples (zero-shot) for prompt-tuning has enabled LLMs to achieve state-of-the-art performance in a broad range of NLP applications. This article by the American Medical Informatics Association (AMIA) NLP Working Group characterizes the opportunities, challenges, and best practices for our community to leverage and advance the integration of LLMs in downstream NLP applications effectively. This can be accomplished through a variety of approaches, including augmented prompting, instruction prompt tuning, and reinforcement learning from human feedback (RLHF). Our focus is on making LLMs accessible to the broader biomedical informatics community, including clinicians and researchers who may be unfamiliar with NLP. Additionally, NLP practitioners may gain insight from the described best practices. We focus on 3 broad categories of NLP tasks, namely natural language understanding, natural language inferencing, and natural language generation. We review the emerging trends in prompt tuning, instruction fine-tuning, and evaluation metrics used for LLMs while drawing attention to several issues that impact biomedical NLP applications, including falsehoods in generated text (confabulation/hallucinations), toxicity, and dataset contamination leading to overfitting. We also review potential approaches to address some of these current challenges in LLMs, such as chain of thought prompting, and the phenomena of emergent capabilities observed in LLMs that can be leveraged to address complex NLP challenge in biomedical applications.

Large language models (LLMs) have exhibited remarkable performance in various natural language processing tasks. Techniques like instruction tuning have effectively enhanced the proficiency of LLMs in the downstream task of machine translation. However, the existing approaches fail to yield satisfactory translation outputs that match the quality of supervised neural machine translation (NMT) systems. One plausible explanation for this discrepancy is that the straightforward prompts employed in these methodologies are unable to fully exploit the acquired instruction-following capabilities. To this end, we propose the TASTE framework, which stands for translating through selfreflection. The self-reflection process includes two stages of inference. In the first stage, LLMs are instructed to generate preliminary translations and conduct self-assessments on these translations simultaneously. In the second stage, LLMs are tasked to refine these preliminary translations according to the evaluation results. The evaluation results in four language directions on the WMT22 benchmark reveal the effectiveness of our approach compared to existing methods. Our work presents a promising approach to unleash the potential of LLMs and enhance their capabilities in MT. The codes and datasets are open-sourced at https://github. com/YutongWang1216/ReflectionLLMMT.

Evaluating gpt-4 for zero-shot classification of bleeding and clotting events: Can large language models serve as second reviewers?

Plagiarism, the unauthorized reuse of text, fueled by the ease of access to online content, is a pressing concern for academia, publishers, and authors. Paraphrasing, a common tactic in textual plagiarism, compounds the problem further. The automatic detection of paraphrased plagiarism in text documents is a fundamental task in Natural Language Processing (NLP), crucial for maintaining academic integrity and authenticity. This paper presents an extensive investigation into Urdu sentential paraphrased plagiarism detection leveraging advanced Deep Neural Networks (DNNs) and Large Language Models (LLMs). The study builds upon the foundational work and proposes modifications to the Deep Text Reuse and Paraphrased Plagiarism Detection (D-TRaPPD) architecture to incorporate state-of-the-art pre-trained LLMs. The proposed approach, SELLM-D-TRaPPD, integrates various language models, including contextualized sentence embedding-based LLMs, language-agnostic and multilingual transformer-based LLMs, and multilingual knowledge-distilled transformer-based LLMs. We evaluated these models against three benchmark Urdu sentential paraphrase corpora—Urdu Sentential Paraphrase Corpus, Urdu Short Text Reuse Corpus, and Semi-automatic Urdu Sentential Paraphrase Corpus. The results demonstrate the effectiveness of SELLM-D-TRaPPD with LLMs, achieving F1 scores of 92.09%, 96.70%, and 98.23%, respectively. A comparative analysis with existing state-of-the-art methods shows significant performance improvements, establishing SELLM-D-TRaPPD as the new leading approach for Urdu sentential paraphrased plagiarism detection. These findings highlight the value of leveraging advanced neural network architectures and pre-trained LLMs in improving the accuracy and effectiveness of paraphrased plagiarism detection in Urdu, addressing a crucial gap in Urdu NLP research.

The rapid advancement of large language models (LLMs) has sparked growing interest in their potential applications within urban planning. These models offer novel capabilities in natural language processing tasks, potentially providing advanced support across various aspects of urban planning. Despite the promises, little is known about how and to what extent LLMs have been applied in the planning literature. This study addresses this gap by conducting a comprehensive literature review using the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) methodology. The review depicts five key domains where LLMs are being applied in urban planning: (a) planning and management; (b) public services and participation; (c) transportation and urban mobility; (d) environmental monitoring and sustainability; and (e) urban design and architecture. Additionally, the review identifies four essential characteristics that LLMs should possess to be effective in urban planning: (a) professionalism; (b) inclusivity; (c) trustworthiness; and (e) convenience. Considering the findings, a conceptual framework is developed that illustrates how these characteristics enhance the flexibility and effectiveness of LLMs in supporting urban planning tasks. This framework offers a theoretical foundation for urban planners to effectively integrate LLMs into practice and provides a roadmap for future research and technological innovations in the application of LLMs within urban environments.

Despite being empowered with alignment mechanisms, large language models (LLMs) are increasingly vulnerable to emerging jailbreak attacks that can compromise their alignment mechanisms. This vulnerability poses significant risks to real-world applications. Existing work faces challenges in both training efficiency and generalization capabilities (i.e., Reinforcement Learning from Human Feedback and Red-Teaming). Developing effective strategies to enable LLMs to resist continuously evolving jailbreak attempts represents a significant challenge. To address this challenge, we propose a novel defensive paradigm called GuidelineLLM, which assists LLMs in recognizing queries that may have harmful content. Before LLMs respond to a query, GuidelineLLM first identifies potential risks associated with the query, summarizes these risks into guideline suggestions, and then feeds these guidelines to the responding LLMs. Importantly, our approach eliminates the necessity for additional safety fine-tuning of the LLMs themselves; only the GuidelineLLM requires fine-tuning. This characteristic enhances the general applicability of GuidelineLLM across various LLMs. Experimental results demonstrate that GuidelineLLM can significantly reduce the attack success rate (ASR) against LLM (an average reduction of 34.17% ASR) while maintaining the usefulness of LLM in handling benign queries.

Abstract. Large language models (LLMs) have revolutionized the field of natural language processing (NLP), demonstrating remarkable capabilities in understanding, generating, and manipulating human language. This comprehensive review explores the development, applications, optimizations, and challenges of LLMs. This paper begin by tracing the evolution of these models and their foundational architectures, such as the Transformer, GPT, and BERT. We then delve into the applications of LLMs in natural language understanding tasks, including sentiment analysis, named entity recognition, question answering, and text summarization, highlighting real-world use cases. Next, we examine the role of LLMs in natural language generation, covering areas such as content creation, language translation, personalized recommendations, and automated responses. We further discuss LLM applications in other NLP tasks like text style transfer, text correction, and language model pre-training. Subsequently, we explore techniques for optimizing and improving LLMs, including model compression, explainability, robustness, and security. Finally, we address the challenges posed by the significant computational requirements, sample inefficiency, and ethical considerations surrounding LLMs. We conclude by discussing potential future research directions, such as efficient architectures, few-shot learning, bias mitigation, and privacy-preserving techniques, which will shape the ongoing development and responsible deployment of LLMs in NLP.

Introduction Advances in large language models (LLMs) have opened new avenues for healthcare applications. Recently, ChatGPT-4 successfully achieved the pass mark >80% in 5 of 10 sleep medicine examination domains, indicating a strong foundational knowledge of sleep medicine. However, the ability to answer USMLE-type multiple-choice questions may not equate to the capacity to offer accurate and comprehensive answers to clinical queries or real-world case scenarios. Current literature exhibits a significant gap in validation research examining the clinical utility of LLMs in evidence-based medicine practice. This investigation aims to evaluate the potential usefulness and reliability of LLMs as adjunctive clinical decision-support tools (namely, “curbside consultants”) in sleep medicine. Methods Six clinical sleep queries and six case scenarios were presented to 6 LLMs including 3 general-purpose LLMs (ChatGPT-4o, Gemini-1.5-Pro, and Llama-3.1-405B) and 3 medical-specialized LLMs (OpenEvidence, Clara AI, and MediGPT). Performance assessment was conducted independently utilizing two independently developed 5-point Likert scales evaluating two primary domains: answer content (accuracy, relevance, comprehensiveness/depth, clarity/coherence, and unique insightfulness) and reference quality (accuracy, relevance, currentness, comprehensiveness/depth, and searchability). Benchmark answers were established through consensus among four sleep medicine specialists. Analysis of variance was used to compare the performance of the LLMs. Results The medical LLMs demonstrated superior overall performance compared to the general LLMs (P< 0.001). The primary distinction was observed in reference quality metrics, where medical LLMs significantly outperformed general LLMs across all parameters: accuracy, relevance, and searchability (p< 0.001), currentness (p=0.001), and comprehensiveness/depth (p=0.010). Notably, Open Evidence achieved the highest reference quality (p< 0.001). In contrast, the answer content analysis revealed no significant overall differences between medical and general LLMs (p=0.659). Most answer content-related metrics, including accuracy, relevance, or unique insightfulness, did not differ significantly (p>0.050). An exception was clarify/coherence, where medical LLMs were superior to general LLMs (p=0.030). Furthermore, MediGPT and ChatGPT-4o displayed better content comprehensiveness/depth relative to other LLMs (p< 0.001). These two LLMs exhibited comparable performance in overall metrics (p=0.615), answer contents (p=0.922), and reference quality (p=0.621). Conclusion Both medical-specialized and general-purpose LLMs show promise as adjunctive decision-support tools in clinical practice. However, substantial improvements in reference quality are critically needed across most LLM platforms. Support (if any)

Recently, Large Language Models (LLMs) have showcased their potential in various natural language processing tasks, including code generation. However, while significant progress has been made in adapting LLMs to generate code for several imperative programming languages and tasks, there remains a notable gap in their application to declarative formalisms, such as Answer Set Programming (ASP). In this paper, we move a step towards exploring the capabilities of LLMs for ASP code generation. First, we perform a systematic evaluation of several state-of-the-art LLMs. Despite their power in terms of number of parameters, training data and computational resources, empirical results demonstrate inadequate performances in generating correct ASP programs. Therefore, we propose LLASP, a fine-tuned lightweight model specifically trained to encode fundamental ASP program patterns. To this aim, we create an ad-hoc dataset covering a wide variety of fundamental problem specifications that can be encoded in ASP. Our experiments demonstrate that the quality of ASP programs generated by LLASP is remarkable. This holds true not only when compared to the non-fine-tuned counterpart but also when compared to the majority of eager LLM candidates, particularly from a semantic perspective. All the code and data used to perform the experiments are publicly available: https://github.com/EricaCoppolillo/LLASP.

In recent years, large language models (LLMs) have demonstrated exceptional ability in natural language processing tasks, yet their potential to enhance geospatial intelligence remains largely untapped. Geospatial data, which is found not only in maps but also in regular text, presents unique opportunities for the application of LLMs. This research seeks to investigate if Large Language Models can serve as accurate sources of geospatial information. To achieve this, we assessed the geospatial capability of 6 open LLMs: Mistral, GPT 3.5 and 4.o, LLaMA 2 and 3, and Gemini, using 30 curated geospatial prompts grouped into three categories: geographic coordinates, basic spatial calculations, and descriptions of places. These prompts were translated into Yoruba to ensure contextual relevance. Subsequently, we employed retrieval-augmented generation (RAG) to enhance the models’ geospatial knowledge base. Our findings revealed that GPT 4.o and Mistral consistently outperformed the other models across all categories and languages, while the RAG drastically improved the LLMs’ knowledge. This study demonstrates the potential of LLMs in being an accurate source of geospatial information through the use of retrieval augmented generation (RAG).

With the rapid development of large language models (LLMs) in natural language processing and generation tasks, researchers are continuously validating their application potential in the field of medical artificial intelligence (AI). Generative Pre-trained Transformer 5 (GPT-5), Pathways Language Model 2 (PaLM-2), Large Language Model Meta AI 3 (Llama-3), Gemini-2.5, and various medical vertical models have demonstrated excellent performance in many medical and health-related tasks. However, LLMs still face key bottlenecks in real-world medical scenarios, including “illusions” slow knowledge updates, and a lack of interpretability. These problems severely restrict the safe deployment of large language models in high-risk medical scenarios and have become a major obstacle to the transition of medical artificial intelligence from research to clinical application. Retrieval-augmented generation (RAG) technology has therefore become an important solution for improving the credibility of medical LLMs. RAG significantly reduces the risk of information errors by retrieving authoritative medical knowledge before generation while maintaining knowledge updates without retraining. A review of research progress on RAG in the medical field is of great theoretical value and practical significance for promoting the design, evaluation, and standardized application of trustworthy medical AI. This review aims to systematically summarize the research progress of RAG in medical scenarios, including the technical frameworks, typical applications, and development trends of three types of methods—naive RAG, advanced RAG, and modular RAG—and further discuss their significance in medical reliability, health equity, and personalized medicine. The naive RAG architecture, through a standard “index-retrieval-generation” process, transforms external knowledge bases into a structured vector space that can be queried by an LLM, achieving positive results in electronic medical record (EMR) summary, preoperative assessment, and medical question answering (QA). However, naive RAG still has limitations in retrieval accuracy and cross-modal processing. To address these shortcomings, advanced RAG methods have been devised that significantly improve the model’s decision-making capabilities by improving retrieval strategies, enhancing inference chains, and introducing self-reflection mechanisms. Furthermore, modular RAG design offers composable, multi-module systems to support multi-source knowledge integration and complex task decomposition. In terms of application value, RAG’s contributions to the healthcare field are primarily reflected in these aspects. On the one hand, it significantly improves the reliability of medical AI by introducing traceable knowledge to reduce illusions. On the other hand, it helps promote healthcare equity by driving a shift toward a patient-centered healthcare model through localized knowledge bases and multilingual support. However, the deployment of RAG in medical scenarios still faces many challenges, such as data privacy risks. Future research should focus on improving self-supervised reflection capabilities and developing cross-modal knowledge fusion technologies. As research develops, RAG is expected to become a core foundational capability of future intelligent healthcare systems, further promoting the development of safe and efficient intelligent healthcare.