Better Ways to Study Regulatory Elephants

David Bates is Chief, Division of General Medicine at Brigham and Women's Hospital, and Medical Director, Clinical and Quality Analysis at Partners HealthCare System, Inc. He is also an Associate Professor in Medicine at Harvard Medical School and has a joint appointment at Harvard School of Public Health in the Department of Health Policy and Management. Dr. Bates received his BS degree in Chemistry from Stanford University, his MD from Johns Hopkins School of Medicine, and his MSc from Harvard School of Public Health (Department of Health Policy and Management). He completed residency training in internal medicine at the Oregon Health Sciences University and a postdoctoral research fellowship in medicine at the Harvard Medical School. Dr. Bates' primary informatics interest has been the use of computerized decision support to improve safety and thereby reduce the costs of care. A particular focus has been on improving the systems by which drugs are given, to reduce the frequency of medication errors and adverse drug events. One study he led demonstrated that implementation of computerized physician order entry reduced the rate of serious medication errors by 55 percent. Other research interests include affecting physicians' decision making, particularly using computerized interventions; quality of care and cost-effectiveness in medical practice; and outcomes assessment. Dr. Bates has been the recipient of numerous awards, including a National Research Service Award; the Henry Christian Award for Excellence in Research; the Culpeper Award; the Young Investigator of the Year from the Society of General Internal Medicine, Northeast Region; Clinical Investigator of the Year, Center for Healthcare Information Management; the Partners in Excellence Award Quality Treatment and Service and Leadership and Innovation; and the Cheers Award for Outstanding Contribution to Medication Error Prevention from the Institute for Safe Medication Practices. Dr. Bates is a Scientific Advisor, SCRIPT Project, Health Care …

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CancerVolume 120, Issue 2 p. 156-157 CancerScopeFree Access Regular colonoscopy could prevent 40% of colorectal cancers Carrie Printz, Carrie PrintzSearch for more papers by this author Carrie Printz, Carrie PrintzSearch for more papers by this author First published: 07 January 2014 https://doi.org/10.1002/cncr.28541AboutSectionsPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onFacebookTwitterLinked InRedditWechat Researchers at the Harvard School of Public Health (HSPH) in Boston, Massachusetts, found that 40% of all colorectal cancers could be prevented if people underwent regular colonoscopy screening. Their results, from a large long-term study, support current guidelines that recommend people of average risk for the disease undergo colonoscopy every 10 years.1 Co-senior author Shuji Ogino, MD, PhD, an associate professor in the department of epidemiology at HSPH, says that previously insufficient evidence existed regarding how much colonoscopy reduces colorectal cancer incidence and mortality, particularly among patients in whom the cancer originates in the proximal part of the colon. Evidence from this study demonstrates that colonoscopy is effective in preventing cancer in both the distal and proximal regions of the colorectum, whereas sigmoidoscopy alone is insufficient for preventing proximal disease, he adds. Dr. Ogino and his colleagues reviewed data from 88,902 participants in both the Nurses' Health Study and Health Professionals Follow-Up Study. Participants completed questionnaires every 2 years between 1998 and 2008, and researchers documented 1815 cases of colorectal cancer and 474 deaths from the disease. They found that colonoscopy and sigmoidoscopy were linked to a decreased risk of either developing colorectal cancer or dying of it. Although colonoscopy was found to lessen the risk of cancers originating in the proximal colon, it was more effective against those arising in the distal colon. The procedure's decreased effectiveness in reducing the risk of tumors developing in the proximal colon may be attributed to molecular and biological differences between the 2 cancers, researchers say. Additional findings include: If all study participants had undergone colonoscopies, an estimated 40% of colorectal cancers, would have been prevented. Individuals who undergo colonoscopies and are cleared of any problems have a significantly reduced risk of colorectal cancer for up to 15 years after the procedure; however, those with a personal history of adenoma or a family history of colorectal cancer should be screened more often. Colorectal cancers diagnosed within 5 years of a colonoscopy had different molecular characteristics compared with those diagnosed more than 5 years after the procedure. They also may be harder to detect and fully remove. Reference 1 Nishihara R, Wu K, Lochhead P, et al. Long-term colorectal-cancer incidence and mortality after lower endoscopy. N Engl J Med. 2013; 369: 1095– 1105. CrossrefCASPubMedWeb of Science®Google Scholar Volume120, Issue215 January 2014Pages 156-157 This article also appears in:CancerScope Archive 2014-2019 ReferencesRelatedInformation

David S. Sheridan Professor of Anaesthesia and Respiratory Therapy, Harvard University, Professor in the Department of Health Policy and Management, Harvard School of Public Health, Chairman, ASTM Subcommittee F29.03.04 on Alarms, Chairman, ISO Subcommittee TC 121, SC 3 on Ventilators and Related Devices, Department of Veterans Affairs Medical Center, Brockton/West Roxbury, 1400V.F.W. Parkway Boston, Massachusetts 02132–4927Medical Director, Respiratory Care Services, The Children's Hospital of Philadelphia, Associate Professor of Anesthesia and Pediatrics, University of Pennsylvania Medical School, Secretary, ASTM Subcommittee F29.03.04 on Alarms, Member, Joint Advisory Group, International Organization for Standardization (ISO) and International Electrotechnical Commission (IEC), Member, Board of Directors, ASTM 34th Street and Civic Center Boulevard Philadelphia, Pennsylvania 19104Professor of Anesthesiology, Duke University Medical Center, Chairman, ASTM Committee F-29 on Anesthesia and Respiratory Equipment, P.O. Box 3094 Durham, North Carolina 27710

April 01 2009 What Makes Terrorists Tick Erica Chenoweth, Erica Chenoweth Erica Chenoweth is Assistant Professor of Government at Wesleyan University. Search for other works by this author on: This Site Google Scholar Nicholas Miller, Nicholas Miller Nicholas Miller is an undergraduate Government major at Wesleyan. Search for other works by this author on: This Site Google Scholar Elizabeth McClellan, Elizabeth McClellan Elizabeth McClellan is an undergraduate Comparative Government and Studio Art double major at Wesleyan. For a longer, more detailed version of this letter, see Erica Chenoweth's website, http://wesfiles.wesleyan.edu/home/echenoweth/web/home.htm. Search for other works by this author on: This Site Google Scholar Hillel Frisch, Hillel Frisch Hillel Frisch is Associate Professor in the Departments of Political Studies and Middle East History at BarIlan University. He thanks Stuart Cohen, Efraim Inbar, and Gordon McCormick for their helpful comments. Search for other works by this author on: This Site Google Scholar Paul Staniland, Paul Staniland Paul Staniland is a Ph.D. candidate in the Department of Political Science and member of the Security Studies Program at the Massachusetts Institute of Technology, and a Research Fellow at the Belfer Center for Science and International Affairs in the Harvard Kennedy School at Harvard University. The author would like to thank Brendan Green, Vipin Narang, Joshua Rovner, and Cyrus Samii for helpful comments. Search for other works by this author on: This Site Google Scholar Max Abrahms Max Abrahms Max Abrahms is a Social Science Predoctoral Fellow in the Center for International Security and Cooperation at Stanford University, and a Ph.D. candidate in the Department of Political Science at the University of California, Los Angeles. He would like to thank Mia Bloom, Martha Crenshaw, Matthew Gottfried, Peter Krause, Jessica Stern, Paul Stockton, and Robbie Totten for their helpful comments. He is especially grateful to Richard English for sharing his expertise over the years on the Irish Republican Army. Search for other works by this author on: This Site Google Scholar Author and Article Information Erica Chenoweth Erica Chenoweth is Assistant Professor of Government at Wesleyan University. Nicholas Miller Nicholas Miller is an undergraduate Government major at Wesleyan. Elizabeth McClellan Elizabeth McClellan is an undergraduate Comparative Government and Studio Art double major at Wesleyan. For a longer, more detailed version of this letter, see Erica Chenoweth's website, http://wesfiles.wesleyan.edu/home/echenoweth/web/home.htm. Hillel Frisch Hillel Frisch is Associate Professor in the Departments of Political Studies and Middle East History at BarIlan University. He thanks Stuart Cohen, Efraim Inbar, and Gordon McCormick for their helpful comments. Paul Staniland Paul Staniland is a Ph.D. candidate in the Department of Political Science and member of the Security Studies Program at the Massachusetts Institute of Technology, and a Research Fellow at the Belfer Center for Science and International Affairs in the Harvard Kennedy School at Harvard University. The author would like to thank Brendan Green, Vipin Narang, Joshua Rovner, and Cyrus Samii for helpful comments. Max Abrahms Max Abrahms is a Social Science Predoctoral Fellow in the Center for International Security and Cooperation at Stanford University, and a Ph.D. candidate in the Department of Political Science at the University of California, Los Angeles. He would like to thank Mia Bloom, Martha Crenshaw, Matthew Gottfried, Peter Krause, Jessica Stern, Paul Stockton, and Robbie Totten for their helpful comments. He is especially grateful to Richard English for sharing his expertise over the years on the Irish Republican Army. Online ISSN: 1531-4804 Print ISSN: 0162-2889 © 2009 by the President and Fellows of Harvard College and the Massachusetts Institute of Technology.2009 International Security (2009) 33 (4): 180–202. https://doi.org/10.1162/isec.2009.33.4.180 Cite Icon Cite Permissions Share Icon Share Facebook Twitter LinkedIn MailTo Views Icon Views Article contents Figures & tables Video Audio Supplementary Data Peer Review Search Site Citation Erica Chenoweth, Nicholas Miller, Elizabeth McClellan, Hillel Frisch, Paul Staniland, Max Abrahms; What Makes Terrorists Tick. International Security 2009; 33 (4): 180–202. doi: https://doi.org/10.1162/isec.2009.33.4.180 Download citation file: Ris (Zotero) Reference Manager EasyBib Bookends Mendeley Papers EndNote RefWorks BibTex toolbar search Search Dropdown Menu toolbar search search input Search input auto suggest filter your search All ContentAll JournalsInternational Security Search Advanced Search This content is only available as a PDF. © 2009 by the President and Fellows of Harvard College and the Massachusetts Institute of Technology.2009 Article PDF first page preview Close Modal You do not currently have access to this content.

From the Department of Health Policy and Management, Harvard School of Public Health, Boston, Massachusetts

Aim of special session What practical advice can Occupational health practitioners give to those at risk and to management for employees: with no obvious risk factors for cancer other than shiftwork, for those with risk factors (strong FHx, gene markers of susceptibility, obesity, benign breast disease, HRT, late menopause, early menarche, late first birth… for breast cancer), those with cancers under treatment or in remission in relation to nightwork, Also is there a threshold effect? (years of exposure, number of shifts, hours of nightwork), Is there any need for concern or preventive measures?: Should shift lengths be shorter?; Should rest breaks should be included; and how should researchers educate shift workers and employers as to how sleep-wake cycles are controlled and How can we maximise sleep quality, sleep duration, and alertness at work? Speakers Prof Eva Schernhammer, Associate Professor, Harvard School of Public Health, Boston, USA, Professor Johnni Hansen Danish Cancer Registry; johnni@cancer.dk. Prof Lin Fritschi, Curtain University Australia/lin.fritschi@curtin.edu.au. Prof Damien McElvenny IOM UK; Damien.McElvenny@iom-world.org. Prof Shelly Tse Lap Ah, Associate Professor, Centre for Occupational and Environmental Health Studies (COEHS), The Chinese University of Hong Kong/shelly@cuhk.edu.hk

South African Journal of EconomicsVolume 38, Issue 4 p. 268-274 The Determinants of Emigration to South Africa, 1950–1967 GENE L. CHAPIN, GENE L. CHAPIN The authors are Assistant Professor, Associate Professor, and Professor of Economics at Ohio University. All calculations were made at the Ohio University Computer Center.Search for more papers by this authorRICHARD K. VEDDER, RICHARD K. VEDDER The authors are Assistant Professor, Associate Professor, and Professor of Economics at Ohio University. All calculations were made at the Ohio University Computer Center.Search for more papers by this authorLOWELL E. GALLAWAY, LOWELL E. GALLAWAY The authors are Assistant Professor, Associate Professor, and Professor of Economics at Ohio University. All calculations were made at the Ohio University Computer Center.Search for more papers by this author GENE L. CHAPIN, GENE L. CHAPIN The authors are Assistant Professor, Associate Professor, and Professor of Economics at Ohio University. All calculations were made at the Ohio University Computer Center.Search for more papers by this authorRICHARD K. VEDDER, RICHARD K. VEDDER The authors are Assistant Professor, Associate Professor, and Professor of Economics at Ohio University. All calculations were made at the Ohio University Computer Center.Search for more papers by this authorLOWELL E. GALLAWAY, LOWELL E. GALLAWAY The authors are Assistant Professor, Associate Professor, and Professor of Economics at Ohio University. All calculations were made at the Ohio University Computer Center.Search for more papers by this author First published: December 1970 https://doi.org/10.1111/j.1813-6982.1970.tb00268.xCitations: 5AboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onFacebookTwitterLinkedInRedditWechat Citing Literature Volume38, Issue4December 1970Pages 268-274 RelatedInformation

Case-Crossover Designs Compared With Dynamic Follow-up Designs

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WHO Director-General announces senior team

Oxford Bulletin of Economics and StatisticsVolume 35, Issue 3 p. 223-231 LEAST SQUARES REGRESSION WITH CAUCHY ERRORS V. KERRY SMITH, V. KERRY SMITH 1Research Associate, Resources for the Future, Inc. and Associate Professor of Economics, State University of New York, Binghamton. I would like to thank an anonymous referee for most helpful suggestions which improve earlier drafts of this paper. All errors rest with the author.Search for more papers by this author V. KERRY SMITH, V. KERRY SMITH 1Research Associate, Resources for the Future, Inc. and Associate Professor of Economics, State University of New York, Binghamton. I would like to thank an anonymous referee for most helpful suggestions which improve earlier drafts of this paper. All errors rest with the author.Search for more papers by this author First published: August 1973 https://doi.org/10.1111/j.1468-0084.1973.mp35003004.xCitations: 8 AboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onFacebookTwitterLinked InRedditWechat Citing Literature Volume35, Issue3August 1973Pages 223-231 RelatedInformation

A wealth of evidence attests that the organs of developing embryos, particularly the developing brain, are acutely sensitive to chemical perturbations. However, scientists know very little about how exposures to specific endogenous chemicals actually impact human development or children’s ability to learn. And there are almost no data on how the vast majority of the 84,000 chemicals currently listed in the Toxic Substances Control Act (TSCA) Inventory1—including most of the 201 compounds known to be neurotoxic to adults and the 1,000 chemicals shown to be neurotoxic to animals2—may affect developing infants. It is also unclear whether testing with animals always provides accurate insights into human developmental susceptibility. A new line of research based on human stem cells is providing important insights into how chemicals may affect neonatal development. Stem cells are the master cells capable of producing some or all of the 200-plus different types of cells in the human body. In time, some researchers believe stem cells may enable scientists to amass far more data on how exposure to environmental chemicals affects human development, particularly the development of the brain. Now is a “critical time to be talking about stem cell research in the environmental health context,” says Tracey Woodruff, director of the Program on Reproductive Health and the Environment at the University of California, San Francisco (UCSF) Medical School.

Juvenile and Family Court JournalVolume 47, Issue 1 p. 21-39 Girls and Gangs: A Review of Recent Research* Randall G. Shelden Ph.D, Corresponding Author Randall G. Shelden Ph.D Randall G. Shelden, Ph.D., is Professor and Chair in the Department of Criminal Justice, University of Nevada-Las Vegas. He is co-author of Girls, Delinquency and Juvenile Justice (Wadsworth) and co-author, along with Tracy and Brown, of Youth Gangs in American Society, (Wadsworth, forthcoming). Department of Criminal Justice University of Nevada-Las Vegas Las Vegas, NV 89154-5009 Department of Political Science LB 8101 Georgia Southern University Statesboro, GA 30460-8101 Department of Sociology/Anthropology University of Michigan Flint, MI 48502Search for more papers by this authorSharon K. Tracy Ph.D, Corresponding Author Sharon K. Tracy Ph.D Sharon K. Tracy, Ph.D., is Associate Professor in the Department of Political Science, Georgia Southern University. She is co-author, along with Shelden and Brown, of Youth Gangs in American Society, (Wadsworth, forthcoming). Department of Criminal Justice University of Nevada-Las Vegas Las Vegas, NV 89154-5009 Department of Political Science LB 8101 Georgia Southern University Statesboro, GA 30460-8101 Department of Sociology/Anthropology University of Michigan Flint, MI 48502Search for more papers by this authorWilliam B. Brown Ph.D, Corresponding Author William B. Brown Ph.D William B. Brown, Ph.D., is Assistant Professor in the Department of Sociology, University of Michigan-Flint. He is co-author, along with Shelden and Tracy, of Youth Gangs in American Society, (Wadsworth, forthcoming). Department of Criminal Justice University of Nevada-Las Vegas Las Vegas, NV 89154-5009 Department of Political Science LB 8101 Georgia Southern University Statesboro, GA 30460-8101 Department of Sociology/Anthropology University of Michigan Flint, MI 48502Search for more papers by this author Randall G. Shelden Ph.D, Corresponding Author Randall G. Shelden Ph.D Randall G. Shelden, Ph.D., is Professor and Chair in the Department of Criminal Justice, University of Nevada-Las Vegas. He is co-author of Girls, Delinquency and Juvenile Justice (Wadsworth) and co-author, along with Tracy and Brown, of Youth Gangs in American Society, (Wadsworth, forthcoming). Department of Criminal Justice University of Nevada-Las Vegas Las Vegas, NV 89154-5009 Department of Political Science LB 8101 Georgia Southern University Statesboro, GA 30460-8101 Department of Sociology/Anthropology University of Michigan Flint, MI 48502Search for more papers by this authorSharon K. Tracy Ph.D, Corresponding Author Sharon K. Tracy Ph.D Sharon K. Tracy, Ph.D., is Associate Professor in the Department of Political Science, Georgia Southern University. She is co-author, along with Shelden and Brown, of Youth Gangs in American Society, (Wadsworth, forthcoming). Department of Criminal Justice University of Nevada-Las Vegas Las Vegas, NV 89154-5009 Department of Political Science LB 8101 Georgia Southern University Statesboro, GA 30460-8101 Department of Sociology/Anthropology University of Michigan Flint, MI 48502Search for more papers by this authorWilliam B. Brown Ph.D, Corresponding Author William B. Brown Ph.D William B. Brown, Ph.D., is Assistant Professor in the Department of Sociology, University of Michigan-Flint. He is co-author, along with Shelden and Tracy, of Youth Gangs in American Society, (Wadsworth, forthcoming). Department of Criminal Justice University of Nevada-Las Vegas Las Vegas, NV 89154-5009 Department of Political Science LB 8101 Georgia Southern University Statesboro, GA 30460-8101 Department of Sociology/Anthropology University of Michigan Flint, MI 48502Search for more papers by this author First published: February 1996 https://doi.org/10.1111/j.1755-6988.1996.tb00744.xCitations: 1 * Portions of this paper will appear in Youth Gangs in American Society, to be published by Wadsworth Publishing Co., Belmont, CA (Spring, 1996). AboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onFacebookTwitterLinked InRedditWechat Citing Literature Volume47, Issue1February 1996Pages 21-39 RelatedInformation

Prelims