Beyond the Bench: Building Blocks of Learning

At the New Mexico Center for Environmental Health Sciences (NMCEHS), community concerns and relationships are as much at the center’s foundation as the latest research techniques. According to center director Scott Burchiel, the unique populations of New Mexico—including a high number of Hispanics and Native American tribes, pueblos, and sovereign nations—steer the center’s course. “One of the things we have tried to do is to determine what these populations’ concerns are for environmental health, because we want our center to be focused on environmental public health, and we want to work on basic research projects that address issues that people in this region are particularly interested in,” he says. Based in Albuquerque as a partnership of The University of New Mexico Health Sciences Center and the Lovelace Respiratory Research Institute (LRRI), the NIEHS-funded center comprises major research cores in environmental cancer and oxidative stress, cardiovascular toxicology, environmental lung disease, and population health and epidemiology. The center also includes world-class facility cores (particularly for inhalation toxicology), a pilot project program to provide funding for small innovative research studies, and an unusually strong community outreach and education program (COEP). Community input is essential, as is trust. “We have investigators who may have certain interests for certain kinds of projects and want to work with communities,” says Burchiel. “But when we go to the community, we find out that [the community has] a different agenda, different interests. We’ve been learning how to work with communities since we’ve had this environmental health center.” It’s a process that involves a lot of development of community relationships and trust relationships. Burchiel says that investigating environmental health problems such as asthma requires a broad definition of environment. He says, “In our center, we define the environment quite broadly. It includes nutritional, social, behavioral, economic, and built environment components. . . . We have not only environmental epidemiologists [but] also social epidemiologists who help us look at social factors in assessing economic and poverty factors.”

Vol. 113, No. 3 EnvironewsOpen AccessBeyond the Bench: Tox-in-a-Box Kris Freeman Kris Freeman Search for more papers by this author Published:1 March 2005https://doi.org/10.1289/ehp.113-a162Cited by:1AboutSectionsPDF ToolsDownload CitationsTrack Citations ShareShare onFacebookTwitterLinked InReddit The Tox Ambassador—a scientist visiting from a nearby university—squeezes several drops of blue dye into three different-sized beakers of water. The audience of sixth-grade students can easily see that although the same amount of dye is put in each beaker, the water in the smallest “baby” beaker turns much darker than that in the larger “big kid” and “adult” beakers. They are learning a key concept in toxicology: that your body size affects your dose, and that the dose makes the poison.Thousands of students have learned about environmental health science through presentations like these based on the Tox-in-a-Box™ resources kit, which includes activities for grades kindergarten through 12 (K–12), slides, demonstrations, instructions, tips for presenters, and a resource manual for teachers. The kit is designed for toxicologists and other environmental and public health professionals—Tox Ambassadors—to use in outreach efforts to students and teachers. It is produced and distributed by the Community Outreach and Education Program (COEP) of the NIEHS Center for Ecogenetics and Environmental Health at the University of Washington.Tox-in-a-Box was originally developed by COEP staff at the request of environmental health professionals who had been invited to give presentations in classrooms and weren’t sure how to explain toxicology to young audiences. Soon COEP staff also began training graduate students to serve as Tox Ambassadors. Since 2000, Tox Ambassadors have given presentations to almost 4,000 K–12 students in western Washington. Many of these presentations have been made through the NIEHS/University of Washington Integrated Environmental Health Middle School Project ( http://depts.washington.edu/ceeh/Outreach/k12.html).When Carlos Mata, a former visiting scholar and Tox Ambassador, returned to his native country of Costa Rica, he launched a program similar to Tox-in-a-Box called EcoAmigos. The EcoAmigos program disseminates basic environmental health information in regional schools. Tox-in-a-Box kits have also been sent to collaborators at the University of Alexandria in Egypt.Tox-in-a-Box fits well with many modules such as environment, biology, chemistry, social studies, risk, safety, reading, and debate. Learning themes include Living in a Chemical World, Routes of Exposure, Risks vs. Benefits, and Tox Tales: A Real Life Component. Overall, teachers give the kit high marks for both the relevance of the material to the students’ interests and concerns, and the ease of integrating the material into the curriculum they already teach.Tox-in-a-Box kits are available for purchase. A brochure is available online at http://depts.washington.edu/ceeh/Outreach/pdf/tib.pdf.Good things in small packages. The Tox-in-a-Box kit (top) has everything needed for a school presentation (left).FiguresReferencesRelatedDetailsCited by Gilbert S and Frevert K (2009) Public Education Information Resources in Toxicology, 10.1016/B978-0-12-373593-5.00073-2, (681-689), . Vol. 113, No. 3 March 2005Metrics About Article Metrics Publication History Originally published1 March 2005Published in print1 March 2005 Financial disclosuresPDF download License information EHP is an open-access journal published with support from the National Institute of Environmental Health Sciences, National Institutes of Health. All content is public domain unless otherwise noted. Note to readers with disabilities EHP strives to ensure that all journal content is accessible to all readers. However, some figures and Supplemental Material published in EHP articles may not conform to 508 standards due to the complexity of the information being presented. If you need assistance accessing journal content, please contact [email protected]. Our staff will work with you to assess and meet your accessibility needs within 3 working days.

More than 3 million children 10 million child deaths annually throughout the world [World Health Organization (WHO) 2005]. Some factors of susceptibility, including race, ethnicity, and socioeconomic status, are generally not well understood in the context of risk assessment. For children’s environmental health the focus is almost exclusively on age-related differences and exposure hazards, without much discussion of the myriad additional factors including nutritional status, preexisting health status, multiple exposures, and gender differences that can affect the life course of a child.

NIEHS Supports Partnerships in Environmental Public Health Linda S. Birnbaum, PhD I would like to start by thanking the journal for inviting me to write an editorial to accompany Dr. Juliana van Olphen and her colleagues’ thoughtful evaluation that focuses on the important topic of community health partnerships.1 As the new director of the National Institute of Environmental Health Sciences (NIEHS) and the National Toxicology Program, I am pleased to take on this role during a time when both the environment and health are top priorities for our country. I am a big supporter of community-based participatory research (CBPR) that ensures community members have an active role in planning, implementing, translating and disseminating research that addresses local environmental health concerns. NIEHS has been a long-standing leader in fostering partnerships between community groups and researchers to better understand environmental causes of disease. Our commitment is demonstrated in a number of ways. For example, NIEHS, in cooperation with the National Cancer Institute, requires that a Community Outreach and Translation Core (COTC) is established in each of our four Breast Cancer and the Environment Research Centers—one of which was the subject of Dr. van Olphen’s independent analysis published in this issue. COTCs conduct essential work to ensure that the views and concerns of the breast cancer advocacy community are heard and that the research findings are disseminated to the public. Developing educational materials for children and adults about breast cancer and the environment, holding public awareness forums and town meetings, and exploring areas of concern or interest to the community are all essential activities led by the COTC to create community participation in environmental health issues such as breast cancer. What van Olphen’s article demonstrates is that COTCs can further advance and promote CBPR principles within research-intensive Centers. NIEHS grantees employing CBPR approaches are contributing to our understanding about breast cancer and the environment. There is a growing body of literature showing that early-life exposures to endocrine disruptors—particularly during gestation and childhood, but also continuing through puberty, first childbirth, and breastfeeding—are critical to later-life breast cancer risk. As researchers learn more about what causes and how to prevent breast cancer, grantees such as those we support through our environmental justice program are spreading the word and empowering communities to take action. Breast cancer advocates in two communities that differ in racial/ethnic and economic character are working in partnership with researchers to assess household exposures to endocrine disrupting compounds, and to develop communication tools for reporting results to affected individuals and communities.2 These research findings are being used by community groups and advocates to affect public health and lead to policy changes. Congress recently recognized the contributions of NIEHS and the National Institutes of Health as a whole for their outstanding work in the breast cancer and environment area, when it passed the “Breast Cancer and Environment Research Act of 2008.”3 The Act looks to NIH to take a lead role in defining the future research agenda for collaborative research efforts related to breast cancer and the environment. NIEHS’ leadership role in translating research on breast cancer and the environment is the outgrowth of the Institute’s commitment to CBPR approaches that promote having the community actively involved in shaping and conducting research and intervention strategies. Since 1995, through its CBPR activities, the Institute has supported principles that have been developed and shared by leaders in the field such as those developed by Barbara Israel et al. 4 and Lawrence Green et al.5 Principles that call for building on the strengths and resources within the community; focusing on the local relevance of public health problems; and disseminating results to all partners are endorsed by NIEHS and are evident in work supported by NIEHS. Recognizing the [End Page 195] continuum of CBPR, the Institute promotes these principles throughout a variety of programs from traditional outreach and education efforts to more complex biomedical, hypothesis-driven research questions that address environmental justice and health disparities issues. To build upon our past accomplishments and to progress our research agenda in this area, we recently sought input from research grantees and members of advocacy...

With the recognition that environmental health has relevance to all nursing and midwifery activities, the aim of this paper is to discuss nurses' and midwives' past and present involvement in environmental health in the UK, where the international situation demonstrates good practice, and the challenges and possibilities for greater and more effective UK-based activity in the future. The association between environmental hazards and adverse health effects has received increasing attention over recent years. In the United States of America (USA), the importance of developing an environmental health role for nurses outside of the "traditional" occupational and environmental health nursing specialty has been recognized and acted upon through education, information programmes and policy developments. In the United Kingdom (UK), the same degree of interest, commitment and activity is somewhat lacking. Little nursing and midwifery activity on environmental health issues has taken place in the UK over recent years. The lack of development in this field may relate to the problems of an already overstretched disease treatment service and the lack of an upstream approach to public health. Theoretical and philosophical influences, as well as individual and organizational obstacles or constraints, exist and may hinder nurses and midwives in their efforts to address the subject. Yet nurses and midwives are the largest group in the National Health Service workforce and this gives enormous potential for effective interventions in environmental health. Whilst barriers and obstacles to nursing and midwifery involvement in environmental health in the UK exist, they are all surmountable and appropriate interventions could prove cost-effective in the middle and long-term. Additionally, they may be viewed as a necessary activity for nurses and midwives in response to real health threats and the expressed worries and concerns of patients and communities.

Jenny Pronczuk de Garbino: A Global Champion for Children’s Health

Abstract. Health and environmental psychology have long been walking side by side. These two disciplines of psychology have imported and applied common psychological frameworks and each of them developed specific theories and methodologies. At a time when humankind faces tremendous challenges ahead (climate change, global warming, ocean sickness, the reemergence of infections pandemics), environmental health is more and more a crucial domain of research. Both environmental psychology and health psychology need to be engaged in environmental health issues in order to enhance planetary health. Environmental psychology traditional fields of research provide understanding about how natural or constructed environments impact human identity, attitudes, and behaviors (more recently, environmental psychology is also investing in determinants of pro-environmental behaviors). On the other hand, health psychology has an extensive comprehensive framework about how to promote healthy habits (i.e., automatically activated behaviors). We live in a global and extremely complex and interconnected world, which promotes syndemic phenomena (several interactive epidemics sharing common etiological factors), also resulting in accelerated depletion of natural resources. This current scenario might justify the development of an Environmental Health Psychology discipline, joining together tools from both environmental psychology and health psychology in a synergic and strategic way.

A meta-analysis is a potentially powerful tool to summarize results from separate, however, closely related research projects. Meta-analyses are conducted at negligible costs and efforts as compared to those required for the acquisition of new raw data, e.g., by clinical trials. As part of systematic assessment of drug effects, meta-analyses form the basis for evidence-based clinical decision making and, moreover, are also used by policy makers, e.g., to determine reimbursement. These benefits have increasingly been recognized in recent years. The Cochrane Collaboration founded in 1993 pioneered in and still promotes the preparation and maintenance of highquality systematic reviews including meta-analysis. It also supports the development of software to conduct metaanalyses. Their Review Manager (RevMan, current version: 5.3.5) is an excellent, comprehensive, simple to use program which is distributed free of charge to academic researchers (see http://www.cochrane.org/, http://tech.cochrane.org/ revman, accessed March 8, 2015, and linked sites of the Cochrane Collaboration). A structured approach addressing most pitfalls is supported by concerted initiatives such as PRISMA for meta-analysis of clinical trials [2] and MOOSE for meta-analysis of observational studies [4]. With these resources, doing a meta-analysis has become a technically simple, straightforward procedure. It may therefore falsely appear that no specific in-depth expertise is required to conduct a meta-analysis, neither medical nor statistical nor pharmacological. Because of the need for information for decisionmaking and the excellent reception of meta-analyses, becoming a “meta-analyst” may seem as an intriguing idea to easily acquire many impact points and reputation and make a splendid career, with the excellent cost to benefit ratio of metaanalysis extending to the “meta-analyst” as an individual scientist—or does it? Some researchers and some science policy makers certainly would agree, although in 2014 published meta-analyses accounted for not more than about 1.3 % of all publications in PubMed (http://www.ncbi. nlm.nih.gov/pubmed/, accessed March 8, 2015). For several years, editors of many journals including the European Journal of Clinical Pharmacology are virtually flooded with meta-analyses. This phenomenon is not limited to the area of clinical pharmacology [1]. The annual exponential increase of published metaanalyses calculated from 1990 to 2014 is pretty constant (Fig. 1). It reaches 1.17-fold (8 %) and considerably exceeds the 1.04-fold (2 %) increase seen for all publications (given as geometric mean and coefficient of variation). From our perception, the number of submitted manuscripts reporting a meta-analysis is growing even faster. The technical/statistical quality of submitted meta-analyses is typically high and shows proper use of the tools available. Does clinical pharmacology or, more generally, biomedical science benefit from this phenomenon? From a scientific point of view, the appropriate starting point for a meta-analysis is a specific research question which has been addressed by a variety of individual research projects, however, which has not been answered with sufficient precision by any of these, say, because individual projects were not large enough. * Uwe Fuhr uwe.fuhr@uk-koeln.de

Selective and nonselective beta-adrenoceptor blockade in hypertension: responses to changes in posture, cold and exercise.

European Journal of Clinical Pharmacology becomes the official organ of European Association for Clinical Pharmacology and Therapeutics

A global public health and child advocacy movement has emerged in recent years that focuses on children’s environmental health. This movement developed out of the growing recognition that women’s and children’s exposures to environmental chemicals are widespread, health outcomes thought to be caused by environmental exposures are increasing among women and children, and governmental regulation of environmental toxicants does not take children’s unique vulnerabilities into account [1, 2]. Many MCH professionals are actively involved in this movement. They hold positions at all levels, including leadership positions, in academic centers, research programs, government agencies, professional societies, and advocacy organizations that address the impact of environmental exposures on children’s health and development [3–5]. In addition, there have been attempts to get the MCH field—as defined in the US by formal MCH training programs and their faculties, programs funded by the Maternal and Child Health Block Grant, professional associations, and this journal—to recognize the relevance of children’s environmental health to its mission. Kotelchuck called for such recognition as early as 1996 [6]. Leiss presented a course syllabus on children’s environmental health developed specifically for MCH students [7]. The MCH section of the American Public Health Association has in the past (but not presently) had an environmental health committee. The authors know of faculty at two different schools of public health who offered to teach courses on this topic under the aegis of their respective MCH departments. (Both of the MCH departments declined the offers.) These efforts have not succeeded in changing the mindset of our field, which still does not recognize the importance to its goals of women’s and children’s environmental exposures. Except for a limited focus on lead and tobacco smoke, environmental health as a topic is absent from the agendas of the major US MCH organizations. It is not present among the issues, projects, and resources highlighted on their websites, nor is it featured at their conferences [8–12]. (The 2009 MCH Epidemiology Conference will include, for the first time, a plenary session on this topic [13].) It is not included among collected MCH course syllabi [10] or in MCH textbooks [14], and it is not part of the core competencies that guide MCH training programs [15]. Environmental health issues are not mentioned in the funding announcements for training programs of the Maternal and Child Health Bureau (except for one brief mention in the schools of public health and pediatric pulmonary center guidances). Articles on this topic in the MCH Journal are rare. Clearly, children’s environmental health is not currently part of our ‘‘corporate consciousness.’’ It is true that many MCH students have access to courses in perinatal epidemiology and reproductive health that consider the role of environmental exposures. But in most Addressing women’s and children’s exposure to environmental toxicants is fundamental to achieving the goals of the MCH field. Children’s environmental health should be part and parcel of MCH training, research, and practice in the twenty-first century.

Gender equality is a manifestation of the equal condition of men and women in obtaining their rights as human beings in order to be able to play a role and participate in political, economic, socio-cultural activities and equality in enjoying the results of development. The environment is very important for human life because a clean environment makes it comfortable to live in, free from various kinds of diseases and air pollution so that the air becomes clean and fresh. The environment becomes unhealthy and can interfere with daily activities and cause diseases that disrupt people's lives. Therefore, there is a need for an active role of men and women (gender) without discrimination in maintaining and preserving a clean and healthy living environment. The purpose of this writing is to find out gender issues in environmental health. The method used is systematic literaure review. Of the 50 selected International articles obtained from Goolge Scholar, PubMed, Emerald Insight, DOAJ, 32 articles discussing Gender and the environment, 5 that meet the Eligibility criteria, were analyzed and came to conclusions. To solve gender problems more effectively, gender socialization or training activities and other forms of activities among officials and communities need to involve both parties, women and men together. By improving gender equality and justice, it is hoped that it will improve and keep the environment clean and healthy. So to encourage the implementation of gender-responsive environmental development not only through policies, programs, and activities but real steps are needed through a massive change movement and a change in mindset and paradigm from all segments of society and if efforts to save the environment and achieve a healthy community life must also be supported by integrating gender equality values

It is human nature to remain committed to endeavors in which one feels personally invested. For the parents and children involved in studies at the Mount Sinai Center for Children’s Environmental Health and Disease Prevention Research, most of whom are from low-income, minority communities such as East Harlem and the Bronx, this sense of commitment plays an important role in their continued participation in such studies. The center’s Community Outreach and Translation Core (COTC) encourages this community kinship by partnering with community organizations to create workshops and educational activities that help keep children and their parents engaged in the studies. According to COTC director Luz Claudio, the COTC staff have designed activities that pick up where organized educational activities at school leave off, encouraging children to learn new, useful information they can share with their parents. The activities are also culturally relevant and easy to take advantage, which makes it easy to keep them going. Claudio says one main goal of these programs is to expose the study participants to realistic, positive role models in the medical profession to encourage their interest in future medical careers. Another is to remind study participants that, through their participation in center studies, they are part of a national effort to improve and protect children’s health. “The COTC educational activities provide direct benefits to the participants that go beyond their participation as study subjects providing data,” says Claudio. “They are truly our partners in the scientific endeavor.” In one current collaborative project popular with kids and parents alike, COTC staff have joined with the nonprofit City Parks Foundation to produce educational workshops aimed at increasing study participants’ physical activity. Claudio points to a study published in the September 2006 issue of the American Journal of Public Health showing that low-income and minority neighborhoods have far fewer commercial physical activity–related facilities available. “This makes our workshops all the more important for these communities because there are few gyms or other sports facilities that are accessible to them,” she says. The workshops offered through the City Parks Foundation collaboration introduce the wonders of the outdoors to children who might not have spent much time there. Workshops include “Trees, Leaves and Worms” (observing nature in action), “My Nature Journal” (recording those observations), and ice-skating excursions in Central Park. “We want parents to learn that they can use New York City parks as learning resources that also provide free health benefits. Parents who become excited by the experiences are more likely to integrate these types of excursions into their children’s lives,” says Claudia DeMegret, director of education at the City Parks Foundation. Other collaborations include family mini-golf with the Randall’s Island Sports Foundation, a “Mad Hot Dancing!” class with salsa dancer Rodney Lopez (featured in the movie Mad Hot Ballroom), and a “Yummy Good” cooking class in partnership with the community organization Little Sisters of the Assumption. The center also distributes regular newsletters and fact sheets telling families where the program’s outdoor activities are conducted. Other workshops are designed specifically to demystify the scientific process and reinforce to the study participants how integral they are to the program. Kids can look at their own cells under a microscope in the “Your Body, Your Cells” workshop. They and their parents also learn to distinguish reliable and unreliable sources of health information on the web in the “On-line for Health” workshop. Scavenger hunts afford the children the opportunity to learn about different kinds of plastics and their varying levels of safety (“Plastics and More Plastics”), and they are also introduced to genetics and heredity (“Do These Genes Make Me Look Fat, and Other Things Genes Do”). Parents appreciate the diversity of entertaining learning opportunities offered to the children through the programs, and note how the kids connect these experiences to their role in the center’s research projects. One parent (who is unidentified to protect the privacy of the study participant) observes, “They enjoy playing in the grass, being in the dirt, collecting leaves. . . . [After an event] they remember and talk about some of the things they did. I think the more they’re exposed to things, the more interested they become in the study.”

In 2004, environmental health issues continue to dominate the policy agenda. Nurses, the first or only point of contact for many patients in underserved communities, are well positioned to advocate for a healthier environment. The development of excellent databases for nurses to learn about environmental health issues and develop competencies provides an opportunity for those wishing to be change agents. Nevertheless, a gap exists for nurses wishing to learn about environmental health nursing advocacy. A program, The Nurse and the Environment: Tools for Action (NETFA), was initiated in 2003 and includes information about the nurse’s advocacy role in environmental health as well as case studies about successful environmental health advocacy campaigns specific to Michigan to promote increased awareness of nurses’ need to develop a strong advocacy role. Such a role should include knowledge of policy and political practices and strategies for influencing current environmental health policy and practices.

ARTICLESHypertension and tissue metal levels following intravenous cadmium, mercury, and zinc Perry HM Jr, A Yunice, M Erlanger, E Schoepfle, and EF Perry Perry HM Jr, A Yunice, M Erlanger, E Schoepfle, and EF PerryPublished Online:01 Sep 1970https://doi.org/10.1152/ajplegacy.1970.219.3.755MoreSectionsPDF (2 MB)Download PDF ToolsExport citationAdd to favoritesGet permissionsTrack citations ShareShare onFacebookTwitterLinkedInWeChat Previous Back to Top Next Download PDF FiguresReferencesRelatedInformation Cited ByA study of relationship between blood mercury concentration and hypertension in residents living in old mine fields and related factors1 January 2019 | Annals of Occupational and Environmental Medicine, Vol. 31, No. 1Cadmium disorganises the scaffolding of gap and tight junction proteins in the hepatic cell line WIF B911 November 2013 | Biology of the Cell, Vol. 105, No. 12The effects of cadmium ions on blood pressure, dopamine-β-hydroxylase activity and on the responsiveness of in vivo preparations to sympathetic nerve stimulation, noradrenaline and tyramine12 April 2011 | Journal of Pharmacy and Pharmacology, Vol. 33, No. 1The impact of long-term past exposure to elemental mercury on antioxidative capacity and lipid peroxidation in mercury minersJournal of Trace Elements in Medicine and Biology, Vol. 17, No. 4Regulation of blood pressure with calcium-dependent dopamine synthesizing system in the brain and its related phenomenaBrain Research Reviews, Vol. 25, No. 1Hypertension induced by methyl mercury in ratsToxicology and Applied Pharmacology, Vol. 89, No. 1The vascular endothelium as a target tissue in acute cadmium toxicityLife Sciences, Vol. 39, No. 16Cadmium and the Cardiovascular SystemStimulation and Depression of the RES by Pharmacological AgentsLead and Cadmium Effect on Host Defense Mechanisms and Toxic Interactions with Bacterial EndotoxinCadmium induced hypothermia in mice: Dose dependent tolerance developmentGeneral Pharmacology: The Vascular System, Vol. 15, No. 3Vascular intracardiac catheterization technique for multiphasic evaluation of rat heart in vivoToxicology and Applied Pharmacology, Vol. 70, No. 2Mechanisms in cardiovascular regulation following chronic exposure of male rats to inorganic mercuryToxicology and Applied Pharmacology, Vol. 69, No. 3Cadmium in animal and human healthThe association of selected hair minerals and anthropometric factors with blood pressure in a normotensive adult populationNutrition Research, Vol. 3, No. 1Teratogenicity, Toxicity and Perinatal Effects of Cadmium6 September 2016 | Human Toxicology, Vol. 1, No. 2Hair Element Concentrations and Hypertension in South Carolina7 September 2016 | Royal Society of Health Journal, Vol. 102, No. 1PROCEEDING OF THE JOINT MEETING OF THE Italian and British Pharmacological Societies19 July 2012 | British Journal of Pharmacology, Vol. 72, No. 1PROCEEDINGS OF THE Briish Pharmacological Society: 9-11th April, 1980 UNIVERSITY OF BRISTOL COMMUNICATIONS19 July 2012 | British Journal of Pharmacology, Vol. 70, No. 1Excretion of cadmium and mercury in rat salivaToxicology and Applied Pharmacology, Vol. 54, No. 1Tissue distribution and retention of cadmium in rats during postnatal development: Minimal role of hepatic metallothioneinToxicology and Applied Pharmacology, Vol. 53, No. 2Factors affecting the acute pressor response to bolus cadmium injectionsPhysiology & Behavior, Vol. 24, No. 2The effect of chelation on the fate of intravenously administered cadmium in ratsJournal of Comparative Pathology, Vol. 89, No. 1Influence of heavy metals on the in vitro interaction between human serum albumin and warfarinBiochemical Pharmacology, Vol. 27, No. 24CADMIUM ALTERS BEHAVIOUR AND THE BIOSYNTHETIC CAPACITY FOR CATECHOLAMINES AND SEROTONIN IN NEONATAL RAT BRAINJournal of Neurochemistry, Vol. 28, No. 4The Biology of CadmiumMedical Clinics of North America, Vol. 60, No. 4A Soluble Cadmium-Binding Component in Rat and Dog SpleenArchives of Environmental Health: An International Journal, Vol. 30, No. 10INTERACTIONS OF Cd++ AND CYSTEINE ON Ca++ CONTENT AND CONTRACTILITY OF ISOLATED AORTAS AND CARDIAC MUSCLESThe Japanese Journal of Pharmacology, Vol. 25, No. 2Pressor Activity in Bovine Kidney HomogenateArchives of Environmental Health: An International Journal, Vol. 29, No. 2Lead, cadmium, endotoxin interaction: Effect on mortality and hepatic functionToxicology and Applied Pharmacology, Vol. 28, No. 2Tissue composition of major and trace elements in uremia and hypertensionJournal of Chronic Diseases, Vol. 27, No. 3 More from this issue > Volume 219Issue 3September 1970Pages 755-761 Copyright & PermissionsCopyright © 1970 by American Physiological Societyhttps://doi.org/10.1152/ajplegacy.1970.219.3.755PubMed5450882History Published online 1 September 1970 Published in print 1 September 1970 Metrics