Bleeding and Clotting Control in ACL Reconstruction

Therapeutic approaches to treat joint contracture after anterior cruciate ligament (ACL) reconstruction have not been established. Arthrofibrosis accompanied by joint inflammation following ACL reconstruction is a major cause of arthrogenic contracture. In this study, we examined whether anti-inflammatory treatment using low-level laser therapy (LLLT) can prevent ACL reconstruction-induced arthrogenic contracture. Rats underwent ACL transection and reconstruction surgery in their right knees. Unoperated left knees were used as controls. After surgery, rats were reared with or without daily LLLT (wavelength: 830 nm; power output: 150 mW; power density: 5 W/cm2; for 120 s/day). We assessed the passive extension range of motion (ROM) after myotomy at one and two weeks post-surgery; the reduction in ROM represents the severity of arthrogenic contracture. ROM was markedly decreased by ACL reconstruction at both time points; however, LLLT partially attenuated the decrease in ROM. One week after ACL reconstruction, the gene expression of the proinflammatory cytokine interleukin-1beta in the joint capsule was significantly upregulated, and this upregulation was significantly attenuated by LLLT. Fibrotic changes in the joint capsule, including upregulation of collagen type I and III genes, shortening of the synovium, and thickening were caused by ACL reconstruction and seen at both time points. LLLT attenuated these fibrotic changes as well. Our results indicate that LLLT after ACL reconstruction could attenuate the formation of arthrogenic contracture through inhibition of inflammation and fibrosis in the joint capsule. Thus, LLLT may become a novel therapeutic approach for ACL reconstruction-induced joint contracture.

Background:Significant variation exists in the published rates of return to sport afteranterior cruciate ligament (ACL) reconstruction (ACLR). Functional outcomesand psychological response to injury have been implicated as factors thatinfluence return to sport. Most studies focus on patients aged in themid-20s, and less is known about this topic in adolescents.Purpose:To report midterm ACLR results for adolescent patients with regard to returnto primary sport, patient-reported outcomes, and reinjury rate.Study Design:Case-control study; Level of evidence, 3.Methods:Adolescent athletes were contacted at a minimum of 2 years after ACLR.Patients completed 2 patient-reported outcome measures, the ACL--Return toSport After Injury (ACL-RSI) and the International Knee DocumentationCommittee (IKDC) subjective form, and responded to questions regardingpreinjury primary sport and level of competition, post-ACLR return toprimary sport status, and reinjury.Results:A total of 74 patients (mean ± SD surgical age, 15.9 ± 1.5 years; follow-upage, 19.9 ± 2.0 years; response rate, 24.5%) completed the surveys at a meanof 4.0 ± 2.0 years after primary ACLR. Outcome scores averaged 90.3 ± 12.3for IKDC and 81.6 ± 20.4 for ACL-RSI. Questionnaire responses indicated that27.0% of patients did not return to or sustain primary sport participationafter ACLR; the principal reasons were poor knee function, team/trainingchange, and fear of another injury. Both IKDC and ACL-RSI scores werestatistically lower in patients who did not successfully return to theirprimary sport in contrast to patients who successfully resumed their primarysport (IKDC, P = .026; ACL-RSI, P <.001). IKDC and ACL-RSI scores were moderately positively correlated withone another (rSpearman = 0.60). There were 18 patients (reinjury rate, 24.3%)who suffered another ACL injury; 8 of these injuries included ipsilateralACL graft tear (retear rate, 10.8%).Conclusion:In our cohort, 73% of adolescent patients successfully returned to theirprimary preinjury sport at a minimum of 2 years after ACLR. Both kneefunction and psychological responses to injury were important in determiningan adolescent athlete’s return to sport. The findings support the use of theIKDC and ACL-RSI at midterm follow-up, with higher scores associated with agreater likelihood of adolescent patients returning to sport after ACLR.

PurposeThis study aimed to compare the short-term outcomes of ACL reconstruction (ACLR) alone, ACLR with lateral tenodesis, and ACL and ALL reconstruction.MethodsA retrospective cohort of prospectively collected data on all ACL procedures was performed at Aspetar Specialized Orthopaedic and Sports Medicine Hospital between January 2020 and January 2021. Patients were treated with ACLR alone, ACLR with lateral tenodesis, or ACLR with ALL reconstruction. The primary outcome was the subjective International Knee Documentation Committee (sIKDC) score. The secondary outcomes were the ACL Return to Sport after Injury (ACL-RSI) scores, pivot shift grade, subjective knee stability, and subjective pain on activity.ResultsA total of 100 cases were included. The most common technique was ACLR with lateral tenodesis (42%), followed by ACLR alone (38%) and ACL with ALL reconstruction (20%). The mean age was 28.15 years (15–60), and 94% of the patients were males. Meniscal procedures were more frequent in the ACLR alone group (65.8%). There was no association between subjective stability, sIKDC, ACL-RSI, and pivot shift grade and the three ACLR techniques while adjusting for age, sex, and concomitant meniscus procedures at six weeks, 12 weeks, six months, and nine months. However, there was a significant decrease in postoperative flexion in the ACL and ALL reconstruction group by a mean of 22° (95% CI − 40.7 − 3.4; P = 0.02) at 6 weeks compared to ACLR alone, which was not evident on later follow-ups.ConclusionACLR with/without lateral augmentation procedures yields similar subjective IKDC, ACL-RSI, pivot shift grade, and subjective knee instability at short-term follow-up. Therefore, lateral extra-articular augmentation procedures are safe to be performed.

ACL injury and reconstruction: Clinical related in vivo biomechanics

Graft failure and secondary meniscal tears are major concerns after anterior cruciate ligament (ACL) reconstruction in young athletes. The aim was to evaluate the link between ACL reconstruction with and without anterolateral ligament (ALL) reconstruction and outcomes in young patients participating in pivoting sports. This was a retrospective study of data collected prospectively. Patients less than 20years, involved in pivoting sports and undergoing primary ACL reconstruction with a quadruple hamstring tendon (4HT) graft or 4HT graft combined with anterolateral ligament reconstruction (4HT + ALL) were included. Survival analysis was performed to identify the prognostic indicators for reoperation due to graft failure or secondary meniscal lesions. Knee laxity was assessed and patient reported outcome measures (PROMs) were collected. A total of 203 patients (mean (± SD) age: 16.3 ± 2years) with a mean follow-up of 4.8 ± 0.9 (range: 3.3‒6.8) years were included. There were 101 4HT and 102 4HT + ALL grafts. Graft rupture rates were 11.9% for 4HT grafts and 5.8% for 4HT + ALL grafts (n.s.). There were 9.9% secondary meniscal procedures for 4HT grafts vs. 1.9% for 4HT + ALL grafts (p = 0.02). With reoperation for graft failure or secondary meniscal lesions at final follow-up as the endpoint, survival was better in the 4HT + ALL group (91.4% vs. 77.8%, respectively; p = 0.03). Absence of ALL reconstruction (HR = 4.9 [95%CI: 1.4-17.9]; p = 0.01) and preoperative side-to-side laxity > 3mm (HR = 3.1 [95%CI: 1.03-9.1]; p = 0.04) were independently associated with an increased rate of reoperations. Mean (± SD) side-to-side laxity was 1.3 ± 1.3mm (range: -2 to 5) for 4HT grafts vs. 0.9 ± 1.3mm (range: -6 to 4.8) for 4HT + ALL grafts (n.s.) 6months post-surgery. The rate of return to the same sport at the same level was 42.2% for 4HT grafts vs. 52% for 4HT + ALL grafts (n.s.). There was no significant difference in subjective outcomes including PROMs between the two groups. Combined ALL + ACL reconstruction reduced the rate of graft failure and secondary meniscal injury in young athletes when compared to ACL reconstruction alone. Subjective results were comparable, with a similar rate of complications. Combined reconstruction should be preferred in this young population. Level IV.

Lateral extra-articular tenodesis (LET) may confer improved rotational stability after anterior cruciate ligament reconstruction (ACLR). Little is known about how LET affects in vivo cartilage contact after ACLR. The aim of this study was to investigate the effect of LET in combination with ACLR (ACLR + LET) on in vivo cartilage contact kinematics compared to isolated ACLR (ACLR) during downhill running. It was hypothesised that cartilage contact area in the lateral compartment would be larger in ACLR + LET compared with ACLR, and that the anterior-posterior (A-P) position of the contact center on the lateral tibia would be more anterior after ACLR + LET than after ACLR. Twenty patients were randomly assigned into ACLR + LET or ACLR during surgery (ClinicalTrials.gov:NCT02913404). At 6months and 12months after surgery, participants were imaged during downhill running using biplane radiography. Tibiofemoral motion was tracked using a validated registration process. Patient-specific cartilage models, obtained from 3T MRI, were registered to track bone models and used to calculate the dynamic cartilage contact area and center of cartilage contact in both the medial and lateral tibiofemoral compartments, respectively. The side-to-side differences (SSD) were compared between groups using a Mann-Whitney U test. At 6months after surgery, the SSD in A-P cartilage contact center in ACLR + LET (3.9 ± 2.6mm, 4.4 ± 3.1mm) was larger than in ACLR (1.2 ± 1.6mm, 1.5 ± 2.0mm) at 10% and 20% of the gait cycle, respectively (p < 0.01, p < 0.05). There was no difference in the SSD in cartilage contact center at 12months after surgery. There was no difference in SSD of cartilage contact area in the medial and lateral compartments at both 6 and 12months after surgery. There were no adverse events during the trial. LET in combination with ACLR may affect the cartilage contact center during downhill running in the early post-operation phase, but this effect is lost in the longer term. This suggests that healing and neuromuscular adaptation occur over time and may also indicate a dampening of the effect of LET over time. (337 /350 words) LEVEL OF EVIDENCE: Level II.

Background: Surgeons and health care systems have received a call to action in an effort to curtail the current opioid epidemic. Purpose: To (1) define the natural history of opioid demand after anterior cruciate ligament reconstruction (ACLR), (2) consider how filling preoperative opioid prescriptions affects opioid demand after ACLR, and (3) evaluate the effect of additional procedures during ACLR and patient age on postoperative opioid demand. Study Design: Cohort study; Level of evidence, 3. Methods: ACLRs performed in the Humana database between 2007 and 2014 were identified using Current Procedural Terminology code 29888. Patients were considered preoperative opioid users if they had filled an opioid prescription in the 3 months preceding surgery. Patients were defined as “chronic” opioid users if they had filled a prescription preoperatively at 1 to 3 months from surgery. Further categorization was performed by identifying patients who only underwent ACLR with no other procedures, those who underwent ACLR with meniscus repair, those who underwent ACLR with meniscectomy, and those who underwent ACLR with microfracture. Categorization by age was also performed. The relative risk (RR) of postoperative opioid use was calculated, and 95% CIs were determined. Results: Over the course of the study period, 4946 ACLRs were performed. At 3 months after their procedure, 7.24% of patients were still filling opioid prescriptions. At 9 and 12 months postoperatively, 4.97% and 4.71% of patients, respectively, were still filling opioid prescriptions. Nearly 35% of patients (1716/4946) were filling opioid pain prescriptions in the 3 months before ACLR. Those filling preoperative opioid prescriptions were 5.35 (95% CI, 4.15-6.90) times more likely to be filling opioid prescriptions at 3 months after ACLR than nonusers (15.38% vs 2.88%, respectively). Those filling opioid prescriptions chronically before surgery were at a 10.50 (95% CI, 7.53-14.64) times increased risk of filling postoperative opioid prescriptions at 5 months. At 5 months postoperatively, patients undergoing ACLR with microfracture had a 1.96 (95% CI, 1.34-2.87) increased risk of filling opioid prescriptions compared with ACLR alone, 2.38 (95% CI, 1.48-3.82) increased risk compared with ACLR with meniscus repair, and 1.51 (95% CI, 1.04-2.19) increased risk compared with ACLR with meniscectomy. Patients younger than 25 years of age had an increased risk of filling opioid prescriptions after ACLR at all time points of the study. Conclusion: Opioid demand after ACLR dropped significantly in the vast majority of patients by the third postoperative month. Surprisingly, 35% of patients undergoing ACLR were observed to be using opioid medication preoperatively, and this study found preoperative opioid use to be a strong predictor of postoperative opioid demand with a 5- to 7-fold increased risk in this patient population. Patients who were filling opioid prescriptions 1 to 3 months from their surgical date were at the highest risk for postoperative opioid utilization. Patients undergoing ACLR with microfracture were at an increased risk of filling opioid prescriptions. Patients less than 25 years of age were at an elevated risk of filling opioid prescriptions at all time points postoperatively.

Background: Aberrant gait biomechanics—ie, lower knee abduction moment (KAM) impulse— are linked to the development of posttraumatic osteoarthritis after anterior cruciate ligament (ACL) injury and ACL reconstruction (ACLR). There is a clinical need to identify modifiable factors, such as kinesiophobia and pain, that may contribute to aberrant gait development after ACLR to advance multimodal rehabilitation strategies. Purpose/Hypothesis: This study aimed to determine associations between preoperative kinesiophobia and pain and gait biomechanics linked to posttraumatic osteoarthritis development at 2 and 4 months after ACLR. We hypothesized that worse preoperative kinesiophobia and pain would be associated with lower KAM impulses in the ACLR limb but not the uninjured limb at 2 and 4 months after ACLR. Study Design: Cohort study; Level of evidence, 2. Methods: Patients within 6 weeks of ACL injury and planning to undergo ACLR with bone-patellar tendon-bone autografts were recruited for the study. Preoperatively, participants completed the Tampa Scale of Kinesiophobia (TSK-11) and Knee injury and Osteoarthritis Outcome Score Pain (KOOS Pain) subscale surveys to assess kinesiophobia (ie, psychological component to pain) and knee pain, respectively. Participants returned at 2 and 4 months after ACLR to complete a 3-dimensional gait biomechanics analysis. KAM impulses during the stance phase were calculated (N*m*s/N*m) for both limbs. Associations of preoperative TSK-11 and KOOS Pain scores with KAM impulses in ACLR and uninjured limbs were analyzed using separate linear regressions. Results: A total of 36 participants (58% women; mean age, 21.4 ± 4.31 years; body mass index, 24.1 ± 3.59 kg/m2 ) completed 3 study visits. Higher preoperative kinesiophobia was associated with lower KAM impulses in the ACLR limb ( R2 = 0.14; P = .02) but not the uninjured limb ( R2 = 0.01; P = .58) at 4 months after ACLR. Preoperative KOOS Pain scores were not associated with KAM impulses in the ACLR and uninjured limbs at 2 and 4 months after ACLR (Δ R2 range, &lt;0.01-0.02; P range = .53-.90). Conclusion: Preoperative kinesiophobia, but not pain, was weakly associated with lower KAM impulses during early to midphases of clinical recovery at 4 months after ACLR.

Preoperative and Intraoperative Predictors of Long-Term Acceptable Knee Function and Osteoarthritis After Anterior Cruciate Ligament Reconstruction: An Analysis Based on 2 Randomized Controlled Trials

Objectives:The incidence of second anterior cruciate ligament (ACL) injury in the first 12 months after ACL reconstruction (ACLR) and return to sport in a young, active population has been reported to be 15 times greater than a previously uninjured cohort. It is unknown if this high relative rate of injury continues beyond the first year after return to sport following ACLR. The tested hypothesis was that the incidence rate of a subsequent ACL injury in the 2 years following ACLR and return to sports would be less than the incidence rate reported within the first 12 months after return to sport, but greater than the ACL injury incidence rate in an uninjured cohort of young athletes.Methods:Seventy-eight subjects who underwent ACLR and were ready to return to a pivoting/cutting sport (RTS) and 47 controls were prospectively enrolled. Each subject was followed for injury and athletic exposure (AE) data for a 24-month period after return to sport. Twenty-three subjects after ACLR and 4 control subjects suffered an ACL injury during this time. Incidence rate ratios (IRR) were calculated to compare the rates (per 1000 athletic exposures [AEs]) of ACL injury in athletes in the ACLR group and control group. For the ACLR group, similar comparisons were conducted for side of injury by sex.Results:The overall incidence rate of a second ACL injury within 24 months after ACLR and RTS (1.39/1000 AE) was nearly 6 times greater (IRR=5.71, 95% CI: 2.0, 22.7, p=0.0003) than healthy control subjects (0.24/1,000 AE). Female ACLR athletes demonstrated 4 times greater rate of injury within 24 months of RTS (IRR=4.51; 95% CI: 1.5-18.2, p=0.0004) than female controls. Within the ACLR group, there was a trend for female subjects to be over two (RR=2.43, 95% CI: 0.8, 8.6) times more likely to suffer a contralateral injury (1.13/1000 AEs) than an ipsilateral injury (0.47/1000 AEs). Overall, 29.5% of athletes suffered a second ACL injury within 24 months of RTS with 20.5% sustaining a contralateral injury and 9.0% incurring an ipsilateral graft re-tear injury. A higher proportion of females (23.7%) suffered a contralateral injury compared to males (10.5%). Conversely, for ipsilateral injuries, the incidence proportion between females (8.5%) and males (10.5%) were found to be similar.Conclusion:These data support the hypothesis that in the 24 months following ACLR and RTS, patients are at greater risk (nearly 6 times) to suffer a subsequent ACL injury compared to young athletes without a history of ACL injury. Additionally, the contralateral limb of female patients appears to be at greatest risk. These 24 month outcome data, analyzed in conjunction with recent 12 month outcome data which noted a 15 times greater risk of ACL injury compared to healthy control subject, indicate that the greatest risk of second ACL injury after ACLR occurs during the initial 12 months after ACLR and RTS than the second year after RTS.

Background: Rates of reinjury, return to play (RTP) at the preinjury level, and hamstring strain injuries in male soccer players after anterior cruciate ligament reconstruction (ACLR) remain unsatisfactory, due to multifactorial causes. Recent insights on intramuscular hamstring coordination revealed the semitendinosus (ST) to be of crucial importance for hamstring functioning, especially during heavy eccentric hamstring loading. Scientific evidence on the consequences of ST tendon harvest for ACLR is scarce and inconsistent. This study intended to investigate the repercussions of ST harvest for ACLR on hamstring muscle function. Hypothesis: Harvest of the ST tendon for ACLR was expected to have a significant influence on hamstring muscle activation patterns during eccentric exercises, evaluated at RTP in a population of male soccer athletes. Study Design: Controlled laboratory study. Methods: A total of 30 male soccer players with a history of ACLR who were cleared for RTP and 30 healthy controls were allocated to this study during the 2018-2019 soccer season. The influence of ACLR on hamstring muscle activation patterns was assessed by comparing the change in T2 relaxation times [ΔT2 (%) = ] of the hamstring muscle tissue before and after an eccentric hamstring loading task between athletes with and without a recent history of ACLR through use of muscle functional magnetic resonance imaging, induced by an eccentric hamstring loading task between scans. Results: Significantly higher exercise-related activity was observed in the biceps femoris (BF) of athletes after ACLR compared with uninjured control athletes (13.92% vs 8.48%; P = .003), whereas the ST had significantly lower activity (19.97% vs 25.32%; P = .049). Significant differences were also established in a within-group comparison of the operated versus the contralateral leg in the ACLR group (operated vs nonoperated leg: 14.54% vs 11.63% for BF [P = .000], 17.31% vs 22.37% for ST [P = .000], and 15.64% vs 13.54% for semimembranosus [SM] [P = .014]). Neither the muscle activity of SM and gracilis muscles nor total posterior thigh muscle activity (sum of exercise-related ΔT2 of the BF, ST, and SM muscles) presented any differences in individuals who had undergone ACLR with an ST tendon autograft compared with healthy controls. Conclusion: These findings indicate that ACLR with a ST tendon autograft might notably influence the function of the hamstring muscles and, in particular, their hierarchic dimensions under fatiguing loading circumstances, with increases in relative BF activity contribution and decreases in relative ST activity after ACLR. This between-group difference in hamstring muscle activation pattern suggests that the BF partly compensates for deficient ST function in eccentric loading. These alterations might have implications for athletic performance and injury risk and should probably be considered in rehabilitation and hamstring injury prevention after ACLR with a ST tendon autograft.

TEMPORAL NEUROMUSCULAR ALTERATIONS OF THE QUADRICEPS AFTER UNILATERAL ANTERIOR CRUCIATE LIGAMENT RECONSTRUCTION Objective: The primary aim of this research was to examine the temporal pattern of neuromuscular quadriceps deficits in both the involved and uninvolved limbs of patients assigned to the control group after anterior cruciate ligament reconstruction (ACLr), by assessing quadriceps strength, voluntary activation, and corticomotor excitability prior to surgery (baseline), three months after ACLr, and six months after ACLr. A secondary aim of this research was to determine whether quadriceps strength, voluntary activation, and/or corticomotor excitability assessed in patients prior to ACLr and/or at three months after surgery, is predictive of lower extremity postural control and/or self-reported function at six months after ACLr. Lastly, a tertiary aim of this research was to determine if a 12week home-based neuromuscular electrical stimulation (Home-NMES) program elicits greater bilateral improvements in quadriceps strength, voluntary activation, and corticomotor excitability of patients at three and six months after ACLr compared to a 12-week standard home-exercise program (control group). Participants: Fifty patients scheduled to undergo unilateral ACLr were randomly allocated to the home-NMES group (19 Female, 6 Male; age: 18.9 ± 5.4 years; height: 170.8 ± 9.7 cm; weight: 74.6 ± 18.5 kg; 28.0±20.0 days-post-injury) or control group (14 Female, 11 Male; age: 19.4 ± 4.5 years; height: 171.1 ± 11.5 cm; weight: 70.7 ± 11.9 kg). Methods: A randomized clinical trial design was used in this study. Prior to ACLr, isometric quadriceps strength and voluntary quadriceps activation were assessed in both limbs of patients, and corticomotor excitability was assessed in the involved limb. Three days after ACLr, both groups were instructed to begin their allocated interventions. The Home-NMES group administered NMES to their involved limb’s quadriceps three sessions a day for 15 minutes, and five days a week for 12 weeks using a portable NMES device. The control group was treated according to the current standard-of-care, but they were also instructed to perform volitional isometric quadriceps contractions for the same duration and frequency as the Home-Based NMES protocol. The outcomes measures were reassessed in both groups at three and six months post-ACLr. Main Outcome Measures: Quadriceps strength and voluntary activation were assessed using maximal voluntary isometric contractions and the superimposed burst technique, respectively. Normalized

Slower Walking Speed Is Related to Early Femoral Trochlear Cartilage Degradation After ACL Reconstruction.

Increased rate of surgery for loss of motion following anterior cruciate ligament reconstruction during COVID-19

Objectives:The incidence of anterior cruciate ligament (ACL) injuries continues to rise,and meniscal injuries are commonly associated with these tears. Treatment ofmeniscal injuries can impart delayed weightbearing range-of-motionrestrictions, which can affect the post-operative rehabilitation protocol.These limitations after a meniscal repair could change how patients aremanaged and progressed through rehab. The effect of the meniscal treatmentand subsequent restrictions on strength recovery after ACL reconstruction(ACLR) is unclear and may affect return-to-play assessments. The purpose ofthis study was to compare strength, jumping performance and patient reportedoutcomes between isolated ACLR patients and those undergoing surgicalintervention for meniscal pathology at the time of ACLR surgery at ascheduled functional testing assessment an average of 6 months aftersurgery. Our hypothesis is that those undergoing meniscal repair will havelower strength recovery due to post-operative restrictions.Methods:In this retrospective cohort study, ACLR patients and healthy controlscompleted patient-reported outcomes (IKDC and KOOS), underwent bilateralisokinetic and isometric strength tests of the knee extensor and flexorgroups, as well as functional hop testing as part of a return-to-sport testbattery at 5-7 months post-operatively. ACLR patients were stratified asisolated ACLR, ACLR+Meniscectomy (ACLR-MS), ACLR+Meniscal Repair (ACLR-MR)and compared to healthy controls. Patients treated with meniscus repair wererestricted to partial weight bearing and to 90 degrees of knee flexion forthe first 6 weeks post-surgery. Comparisons were performed between meniscaltreatment groups with regard to demographics, patient reported outcomesscales, knee extensor and flexor strength, while stratifying by grafttype.Results:305 participants, including 165 ACLR patients (50 isolated ACLR, 71 ACLR +Meniscal Repair, 44 ACLR + Meniscectomy) and 140 healthy controls wereincluded with an average time post-operatively to functional testing of5.96±0.47 months. Heathy controls demonstrated higher subjective kneefunction, unilateral peak extensor torque, and limb symmetry than allmeniscal subgroups (p<.001). There were no differences between the IKDC,KOOS subscales, or in unilateral or limb symmetry measures of peak kneeextensor or flexor torque between ACLR, ACLR+MS, and ACLR+MR patients (allp-values>.05).Conclusions:Persistent weakness, asymmetry and reduced subjective outcome scores measuredat approximately 6 months post index surgery were not influenced by meniscustreatment. Knee flexor and extensor strength, limb symmetry, and patientreported outcomes did not significantly differ across patients undergoingisolated ACLR, ACL + Meniscus Repair, and ACL + meniscectomy. These findingssuggest that the weightbearing and range-of-motion restrictions associatedwith meniscus repair recovery do not result in loss of early strength orpatient reported outcomes, and they can be progressed through therapyaccordingly.