- Conference Article
1
- 10.24466/ijbschs.19.2_7
A Classification Method of Coronary Heart Disease Databases by Clonal Selection Algorithm with Immunological Memory Cell
- Oct 01, 2014
- International Journal of Biomedical Soft Computing and Human Sciences: the official journal of the Biomedical Fuzzy Systems Association
- Tsuyoshi Ichimura + 1 more +1
The Coronary Heart Disease Database (CHD_DB) is based on actual measurements of the Framingham Heart Study - one of the most famous prospective studies of cardiovascular dis- ease. The CHD_DB includes more than 6,500 records indicating the development of coronary heart disease (CHD). The data set is statistically proved to be an effective as a benchmark test. This paper describes the classification result of CHD_DB by using some learning methods. Especially, a com- putational implementation of the clonal selection principle that explicitly takes into account the af- finity maturation of the immune response was well discussed. Antibodies generated by the clonal selection algorithm are clustered in some categories according to the affinity maturation, so that immunological memory cells which respond to the specified pathogen are created to record those antibodies. Such observations supply the inspiration for the Clonal Selection Algorithm with Im- munological Memory Cells. For the data set, our proposed method shows about 99.6% classifica- tion capability of training data.
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