DATA-DRIVEN FAILURE PREDICTION IN BRITTLE MATERIALS: A PHASE FIELD-BASED MACHINE LEARNING FRAMEWORK

Machine learning framework for predicting failure mode and shear capacity of ultra high performance concrete beams

A method is proposed for reconstructing spanwise cross-sectional data of a cavitating turbulent flow field around a 2D hydrofoil to a 3D flow field using supervised machine learning (ML). One of the variables of interest was the cross-sectional pseudomeasurement data of particle image velocimetry. Therefore, the spanwise component w of velocity was not obtained; that is, it cannot be input into neural networks (NN). To compensate for this, we introduced a mass conservation error into the loss function of ML. The computational fluid dynamics (CFD) data for the training were obtained using large-eddy simulation with a homogeneous fluid model for cavitation. The super-resolution convolutional neural network (SRCNN) was adopted for the supervised ML framework. As a result, under the attached sheet cavitation mode, which corresponds to a quasi-steady condition, prediction was relatively simple. In contrast, under sheet/cloud cavitation mode, which is a strongly unsteady condition, the learning curve exhibited oscillations, suggesting that learning is difficult. Physical variables with a uniform distribution in the homogeneous spanwise direction can be reconstructed with high accuracy even under unsteady conditions, whereas the rotational components of streamwise vortices, which are nonuniform in the spanwise direction and have high spatiotemporal frequencies, fluctuate even under quasi-steady conditions, making them extremely difficult to reconstruct. When the loss function is augmented with a mass conservation error, the accuracy of the w reconstruction is improved as the NN attempts to satisfy the conservation of mass.

Machine Learning (ML) algorithms, as the core technology in Artificial Intelligence (AI) applications, such as self-driving vehicles, make important decisions by performing a variety of data classification or prediction tasks. Attacks on data or algorithms in AI applications can lead to misclassification or misprediction, which can fail the applications. For each dataset separately, the parameters of ML algorithms should be tuned to reach a desirable classification or prediction accuracy. Typically, ML experts tune the parameters empirically, which can be time consuming and does not guarantee the optimal result. To this end, some research suggests an analytical approach to tune the ML parameters for maximum accuracy. However, none of the works consider the ML performance under attack in their tuning process. This paper proposes an analytical framework for tuning the ML parameters to be secure against attacks, while keeping its accuracy high. The framework finds the optimal set of parameters by defining a novel objective function, which takes into account the test results of both ML accuracy and its security against attacks. For validating the framework, an AI application is implemented to recognize whether a subject's eyes are open or closed, by applying k-Nearest Neighbors (kNN) algorithm on her Electroencephalogram (EEG) signals. In this application, the number of neighbors (k) and the distance metric type, as the two main parameters of kNN, are chosen for tuning. The input data perturbation attack, as one of the most common attacks on ML algorithms, is used for testing the security of the application. Exhaustive search approach is used to solve the optimization problem. The experiment results show k = 43 and cosine distance metric is the optimal configuration of kNN for the EEG dataset, which leads to 83.75% classification accuracy and reduces the attack success rate to 5.21%.

Hematology research has greatly benefited from the integration of diverse biological data resources and advanced machine learning (ML) frameworks. This integration has not only deepened our understanding of blood diseases such as leukemia and lymphoma, but also enhanced diagnostic accuracy and personalized treatment strategies. By applying ML algorithms to analyze large-scale biological data, researchers can more effectively identify disease patterns, predict treatment responses, and provide new perspectives for the diagnosis and treatment of hematologic disorders. Here, we provide an overview of the current landscape of biological data resources and the application of ML frameworks pertinent to hematology research.

This paper presents the development of a novel virtual reality (VR) machine learning (ML) framework that incorporates haptic feedback to improve sports training scenarios. The framework uses You Look Only Once (YoLo) for object detection, and combines it with ensemble learning to analyze the performance of athletes in a simulated environment and provide real-time feedbacks. The system includes haptic feedback devices that are controlled via Grey Wolf Optimization (GWO) to simulate the physical sensation of a real-world sports scenario, allowing athletes to experience the sensation of force, impact, and movements. The proposed system was tested using a group of professional athletes who participated in various sports, including football, basketball, and tennis. The athletes were asked to perform various training scenarios in the virtual environment, and their performance was compared with their real-world performance levels. The results showed that the proposed system improved the athletes' performance significantly, as they were able to receive immediate and accurate feedback on their movements, and the haptic feedback provided a realistic sensory experience that enhanced their trainings. The proposed research has the potential to revolutionize sports training by providing athletes with an efficient and effective way to improve their performance in a set of safe and controlled environments. The system can be customized to suit various sports and training scenarios, and the ML algorithms can be trained on large datasets to improve their accuracy and effectiveness. The incorporation of haptic feedback provides a unique and realistic experience, making the training more engaging and effective under real-time scenarios. The proposed system showcased an accuracy 93.5%, with 3.5% higher precision, and 4.9% higher recall than existing models, which has the potential to enhance athletic performance and revolutionize the way athletes train for different sports.

A review of supervised machine learning algorithms and their applications to ecological data

Background and purposeThis study aims to develop a robust and user-friendly prediction model for radiation-induced hypothyroidism (RIHT) in nasopharyngeal carcinoma (NPC) patients.Materials and methodsNPC patients treated with IMRT between Jan. 2019 and Dec. 2021 were randomly assigned to a training cohort (n = 328) and a validation cohort (n = 141) at a ratio of 7:3. A total of 33 clinical and dose-volume variables were collected. Significant variables (p < 0.05) were identified through univariate Cox analysis and further refined using a 101-combination machine learning (ML) framework to develop a robust predictive model. The model was subsequently simplified through multivariate Cox analysis and a nomogram. Finally, the performance of the model was evaluated using the C-index, calibration plots, and decision curve analysis.ResultsUsing a 101-combination ML framework, we developed a predictive model for RIHT in NPC. The Coxboost + RSF method with 11 predictors achieved the best performance (C-index: 0.91 [training], 0.71 [validation]). A simplified five-variable model (pre-treatment TSH, TSH-to-thyroid-volume ratio, age, V45, V20) was created via multi-cox regression, with a C-index of 0.80 [training] and 0.71 [validation]. High-risk patients had significantly higher three-year RIHT incidences (72.3% vs. 18.6%, p < 0.0001) in the training cohort, and 67.9% versus 24.4% (p < 0.0001) in the validation cohort. The model showed strong calibration and confirmed clinical utility through decision curve analysis, supporting its use in personalized treatment planning.ConclusionWe developed a ML framework to identify key predictive factors for RIHT, which was simplified into a five-variable model for clinical use, offering a robust tool for predicting RIHT risk in decision-making.Supplementary InformationThe online version contains supplementary material available at 10.1186/s13014-025-02725-5.

Hospital-acquired complications (HACs) have an adverse impact on patient recovery by impeding their path to full recovery and increasing healthcare costs. The aim of this study was to create a HAC risk prediction machine learning (ML) framework using hospital administrative data collections within North Metropolitan Health Service (NMHS), Western Australia. A retrospective cohort study was performed among 64,315 patients between July 2020 to June 2022 to develop an automated ML framework by inputting HAC and the healthcare site to obtain site-specific predictive algorithms for patients admitted to the hospital in NMHS. Univariate analysis was used for initial feature screening for 270 variables. Of these, 77 variables had significant relationship with any HAC. After excluding non-contemporaneous data, 37 variables were included in developing the ML framework based on logistic regression (LR), decision tree (DT) and random forest (RF) models to predict occurrence of four specific HACs: delirium, aspiration pneumonia, pneumonia and urinary tract infection. All models exhibited similar performance with area under the curve scores around 0.90 for both training and testing datasets. For sensitivity, DT and RF exceeded LR performance while on average, false positives were lowest for LR-based models. Patient's length of stay, Charlson Index, operation length and intensive care unit stay were common predictors. Integrating ML-based risk detection systems into clinical workflows can potentially enhance patient safety and optimise resource allocation. LR-based models exhibited best performance. We have successfully developed a "real-time" risk prediction model, where patient risk scores are calculated and reviewed daily.

Eutectic alloys have garnered significant attention due to their promising mechanical and physical properties, as well as their technological relevance. However, the discovery of eutectic compositionally complex alloys (ECCAs) (e.g. high entropy eutectic alloys) remains a formidable challenge in the vast and intricate compositional space, primarily due to the absence of readily available phase diagrams. To address this issue, we have developed an explainable machine learning (ML) framework that integrates conditional variational autoencoder (CVAE) and artificial neutral network (ANN) models, enabling direct generation of ECCAs. To overcome the prevalent problem of data imbalance encountered in data-driven ECCA design, we have incorporated thermodynamics-derived data descriptors and employed K-means clustering methods for effective data pre-processing. Leveraging our ML framework, we have successfully discovered dual- or even tri-phased ECCAs, spanning from quaternary to senary alloy systems, which have not been previously reported in the literature. These findings hold great promise and indicate that our ML framework can play a pivotal role in accelerating the discovery of technologically significant ECCAs.

P125. Development of a novel ensemble machine learning algorithm for prediction of complications and readmission after anterior cervical spinal fusion

Today, the use of artificial intelligence in electron optics, as in many other fields, has begun to increase. In this scope, we present a machine learning framework to predict experimental cross-section data. Our framework includes 8 deep learning models and 13 different machine learning algorithms that learn the fundamental structure of the data. This article aims to develop a machine learning framework to accurately predict double-differential cross-section values. This approach combines multiple models such as convolutional neural networks, machine learning algorithms, and autoencoders to create a more robust prediction system. The data for training the models are obtained from experimental data for different atomic and molecular targets. We developed a methodology for learning tasks, mainly using rigorous prediction error limits. Prediction results show that the machine learning framework can predict the scattering angle and energy of scattering electrons with high accuracy, with an R-squared score of up to 99% and a mean squared error of &lt;0.7. This performance result demonstrates that the proposed machine learning framework can be used to predict electron scattering events, which could be useful for applications such as medical physics.

The rapid spread of contagious diseases poses a colossal threat to human existence. Presently, the emergence of coronavirus COVID-19 which has rightly been declared a global pandemic resulting in so many deaths, confusion as well as huge economic losses is a challenge. It has been suggested by the World Health Organization (WHO) in conjunction with different Government authorities of the world and non-governmental organizations, that efforts to curtail the COVID-19 pandemic should rely principally on measures such as social distancing, identification of infected persons, tracing of possible contacts as well as effective isolation of such person(s) for subsequent medical treatment. The aim of this study is to provide a framework for monitoring Movements of Pandemic Disease Patients and predicting their next geographical locations given the recent trend of infected COVID-19 patients absconding from isolation centres as evidenced in the Nigerian case. The methodology for this study, proposes a system architecture incorporating GPS (Global Positioning System) and Assisted-GPS technologies for monitoring the geographical movements of COVID-19 patients and recording of their movement Trajectory Datasets on the assumption that they are assigned with GPS-enabled devices such as smartphones. Accordingly, fifteen (15) participants (patients) were selected for this study based on the criteria of residency and business activity location. The ensuing participants movements generated 157, 218 Trajectory datasets during a period of 3 weeks. With this dataset, mining of the movement trace, Stay Points (hot spots), relationships, and the prediction of the next probable geographical location of a COVID-19 patient was realized by the application of Artificial Intelligence (AI) and Data Mining techniques such as supervised Machine Learning (ML) algorithms (i.e., Multiple Linear Regression (MLR), k-Nearest Neighbor (kNN), Decision Tree Regression (DTR), Random Forest Regression (RFR), Gradient Boosting Regression (GBR), and eXtreme Gradient Boosting regression(XGBR) as well as density-based clustering methods (i.e., DBSCAN) for the computation of Stay Points (hot spots) of COVID-19 patient. The result of this study showed clearly that it is possible to determine the Stay Points (hot spots) of a COVID-19 patient. In addition, this study demonstrated the possibility of predicting the next probable geographical location of a COVID-19 patient. Correspondingly, Six Machine Learning models (i.e., MLR, kNN, DTR, RFR, GBR, and XGBR) were compared for efficiency, in determining the next probable location of a COVID-19 patient. The result showed that the DTR model performed better compared to other models (i.e., MLR, kNN, RFR, GBR, XGBR) based on four evaluation matrices (i.e., ACCURACY, MAE, MSE, and R2) used. It is recommended that less developed Countries consider adopting this framework as a policy initiative for implementation at this burgeoning phase of COVID-19 infection and beyond. The same applies to the developed Countries. There is indication that GPS Trajectory dataset and Machine Learning algorithms as applied in this paper, appear to possess the potential of performing optimally in a real-life situation of monitoring a COVID-19 patient. This paper is unique given its ability to predict the next probable location of a COVID-19 patient. In the review of extant literature, prediction of the next probable location of a COVID-19 patient was not in evidence using the same Machine Learning algorithms.

Background and aimOver the past decades, we have witnessed an immense expansion in the arsenal and performance of machine learning (ML) algorithms. One of the most important fields that could benefit from these advancements is biomedical science. To streamline the training and evaluation of binary classifiers, we constructed a universal and flexible ML framework that uses tabular biomedical data as input.Methods and resultsOur framework requires the input data to be provided as a comma-separated values file, in which rows correspond to subjects and columns represent different features. After reading the content of this file, the framework enables the users to perform outlier detection, handle missing values, rescale features, and tackle class imbalance. Then, hyperparameter tuning, feature selection, and internal validation are performed using nested cross-validation. If an additional dataset is available, the framework also provides the option for external validation. Users may also compute SHapley Additive exPlanations values to interpret the individual predictions of the model and identify the most important features. Our ML framework was implemented in Python (version 3.9), and its source code is freely available via GitHub. In the second part of this paper, we also demonstrate the usage of the framework through a case study from the field of cardiovascular imaging.ConclusionsThe proposed ML framework enables the efficient training and evaluation of binary classifiers on tabular biomedical data. We hope our framework will serve as a useful resource for both learning and research purposes and will promote further innovation.

We present sql4ml, a framework for expressing machine learning (ML) algorithms in a relational database management system (RDBMS). The user writes the objective function of an ML model as a SQL query, then sql4ml translates the query into an equivalent TensorFlow (TF) graph, which can be automatically differentiated and optimized to learn the model weights. Sql4ml makes the database a unified programming environment for feature engineering, learning/inference, and evaluating models. The proposed approach is more expressive than using ready-made ML algorithms, but abstracts away the details of the training process. We present the architecture of sql4ml and describe the method for translating an objective function in SQL to a TensorFlow representation. We show how recent ideas from Factorized ML [7] can be leveraged to efficiently move data between a database and an ML framework. Finally, we present experimental results regarding both the proposed translation and the optimization techniques for data transfer. Our results show that translation time is negligible compared to time for data processing, and that the optimization techniques achieve up to 50% improvement in the export runtime and up to 85% decrease in the size of the exported data.

Introduction: Heart failure (HF) in critical care settings exhibits complex interactions with glycemic dysregulation. Traditional metrics fail to capture dynamic glucose fluctuations linked to poor outcomes. This study defines ICU-specific glycemic targets and establishes a machine learning (ML) framework integrating novel glucose indicators to predict 28-day mortality. Methods: Cohort: 18,211 ICU HF patients (MIMIC-IV, 2008-2019). Analysis: 1. Glycemic Metrics: Calculated time-weighted average glucose (TWABG), time-in-range (TIR), time-below-range (TBR), time-above-range (TAR) 2. Association Studies: Restricted cubic splines (RCS) to identify optimal glycemic ranges. Multivariable Cox regression with adjustment and subgroup analysis with interaction testing. 3. ML Modeling: Dual-stage feature selection: Lasso regression and Boruta algorithm. Model development: Developed models using 14 algorithms; SHAP interpretation applied to best-performing model (highest ROC-AUC). Validation: SHAP analysis of an exemplar case demonstrated individualized mortality risk interpretation without formal model validation. Results: 1. Optimal Glycemic Ranges: Patients within the optimal TWABG range (85–133 mg/dL) demonstrated the lowest mortality (15.09%,P< 0.001), with improved survival associated with both higher time-in-range (TIR) proportion and absence of glycemic excursions (time-below-range [TBR] or time-above-range [TAR] exposure) 2. ML Prediction: Feature selection via Lasso regression identified 30 predictors. Boruta algorithm confirmed 29 significant features. The optimized XGBoost model predicted 28-day mortality with AUC 0.779 (0.762-0.796) Conclusions: Maintaining blood glucose within TWABG 85–133 mg/dL and maximizing TIR significantly reduces 28-day mortality in ICU HF patients, while avoiding excursions independently improves survival. Our ML framework, integrating dynamic glucose metrics with clinically selected features, accurately predicted mortality risk (AUC 0.779). Findings advocate ICU-specific glucose management and demonstrate ML’s potential for risk stratification and personalized interventions.