• Open Access IconOpen Access
  • https://doi.org/10.3389/fninf.2021.738342.s001Copy DOI Icon

Data_Sheet_1.docx

  • Dec 2, 2021
  • Figshare
  • Ruslan Masharipov (11562502) +6 more
Show More
  • Abstract
  • PDF
  • Literature Map
  • Similar Papers
Abstract

Classical null hypothesis significance testing is limited to the rejection of the point-null hypothesis; it does not allow the interpretation of non-significant results. This leads to a bias against the null hypothesis. Herein, we discuss statistical approaches to ‘null effect’ assessment focusing on the Bayesian parameter inference (BPI). Although Bayesian methods have been theoretically elaborated and implemented in common neuroimaging software packages, they are not widely used for ‘null effect’ assessment. BPI considers the posterior probability of finding the effect within or outside the region of practical equivalence to the null value. It can be used to find both ‘activated/deactivated’ and ‘not activated’ voxels or to indicate that the obtained data are not sufficient using a single decision rule. It also allows to evaluate the data as the sample size increases and decide to stop the experiment if the obtained data are sufficient to make a confident inference. To demonstrate the advantages of using BPI for fMRI data group analysis, we compare it with classical null hypothesis significance testing on empirical data. We also use simulated data to show how BPI performs under different effect sizes, noise levels, noise distributions and sample sizes. Finally, we consider the problem of defining the region of practical equivalence for BPI and discuss possible applications of BPI in fMRI studies. To facilitate ‘null effect’ assessment for fMRI practitioners, we provide Statistical Parametric Mapping 12 based toolbox for Bayesian inference..

Loading PDF

Similar Papers
  • Dissertation
  • Citations1

Precision science with Einstein Telescope

  • Feb 03, 2026
  • Harsh Bharatbhai Narola
  • Research Article
  • Citations5

Hypothesis tests

  • May 14, 2019
  • BJA Education
  • J Walker
  • Research Article
  • Citations6

Step‐stress life‐testing under tampered random variable modeling for Weibull distribution in presence of competing risk data

  • Nov 27, 2023
  • Quality and Reliability Engineering International
  • Farha Sultana +2
  • Research Article
  • Citations11

Model comparison for the density structure along solar prominence threads

  • Jun 01, 2015
  • Astronomy & Astrophysics
  • I Arregui +1
  • Research Article
  • Citations14

Inferred support for disturbance‐recovery hypothesis of North Atlantic phytoplankton blooms

  • Oct 01, 2015
  • Journal of Geophysical Research: Oceans
  • Matthew J Smith +3
  • Research Article
  • Citations2

Structural Time Series Model using Hamiltonian Monte Carlo for Rice Price

  • Oct 02, 2023
  • Engineering, MAthematics and Computer Science Journal (EMACS)
  • Rifdatun Ni'Mah
  • Preprint Article

EnKF and EM based parameter estimation of a convective gravity wave parameterization using Strateole 2 constant level balloon data

  • Mar 14, 2026
  • François Lott +3
  • Preprint Article

Bayesian Inference of Rheological Parameters from Observations Before and After the Tohoku Earthquake

  • Mar 11, 2024
  • Rob Govers +4
  • Research Article
  • Citations18

Order restricted Bayesian inference for exponential simple step-stress model

  • Nov 04, 2016
  • Communications in Statistics - Simulation and Computation
  • D Samanta +3
  • Research Article
  • Citations3

A Closer Look at Correction for False Discovery Bias When Making Multiple Comparisons

  • Dec 01, 2009
  • Journal of Forensic Economics
  • John D Finnerty
  • Research Article
  • Citations91

Experimental design and statistical methods for classical and bioequivalence hypothesis testing with an application to dairy nutrition studies.

  • Jan 01, 2004
  • Journal of animal science
  • Robert J Tempelman
  • PDF
  • Dissertation

Testing Theory-Based Quantitative Predictions with New Behaviors

  • Apr 24, 2013
  • Leslie Ann Brick
  • Research Article
  • Citations85

Effect size, confidence intervals and statistical power in psychological research

  • Jan 01, 2015
  • Psychology in Russia: State of the Art
  • Arnoldo Téllez +2
  • PDF
  • Research Article
  • Citations40

Bayesian and maximum likelihood phylogenetic analyses of protein sequence data under relative branch-length differences and model violation

  • Jan 01, 2005
  • BMC Evolutionary Biology
  • Jessica C Mar +2
  • Research Article
  • Citations25

A Bayesian Analysis of Evidence in Support of the Null Hypothesis in Gerontological Psychology (or Lack Thereof).

  • Mar 16, 2019
  • The journals of gerontology. Series B, Psychological sciences and social sciences
  • Christopher R Brydges +1
Cactus Communications logo

Copyright 2026 Cactus Communications. All rights reserved.