Deep convolutional neural network and IoT technology for healthcare.

Drug screening is an important step in the development of new drugs. Through appropriate experimental methods and screening models, drugs with specific bioactivity can be transferred from laboratory research to clinical application. Nowadays, traditional efficiency of drug experimentation has been unable to meet the needs of our society. With the rapid development of computer technology, computer-assisted diagnosis and treatment have been gradually accepted and recognized by clinicians and patients. Drug screening process at the cellular level was studied in this paper. We not only compared the advantages and disadvantages of deep learning models and traditional machine learning methods, but also analyzed the performance of different deep learning models. First, Hela cells injected with different anti-stress drugs were divided into groups for experiment. G3BP, TIA-1 and the nucleus were labeled, respectively. The images were obtained using a single-photon microscope. Then, we distinguished the images of Hela cells treated with different drugs through visual observation, traditional machine learning (LBP/Gabor+SVM) and deep learning algorithms (VGGNet, GoogLeNet, ResNext and DenseNet), respectively. Experimental results showed that compared with visual observation, traditional machine learning and deep learning algorithms had better objectivity. Furthermore, deep learning models all had good classification performance. The highest average correct recognition rate was 92.97%, while that of the traditional method was only 80.93%. Therefore, drug screening methods based on deep learning could assist in screening the optimal treatment drugs, which help clinicians choose appropriate therapy.

Deep leaning in food safety and authenticity detection: An integrative review and future prospects

Feature mining for encrypted malicious traffic detection with deep learning and other machine learning algorithms

The dynamic modulus (|E*|) of hot-mix asphalt (HMA) is a crucial mechanistic characteristic essential in defining the strain response of asphalt concrete (AC) mixtures under varying loading rates and temperatures. This paper aims to conduct a comprehensive investigation of classical machine learning (ML) and deep learning (DL) algorithms as applied to the prediction of |E*| and compare their performance with renowned |E*| regression models (Witczak NCHRP 1-37A, Witczak NCHRP 1-40D, and Hirsch). Eight state-of-the-art ML and DL algorithms are attempted with diverse structures, including multiple linear regression (MLR), decision trees (DT), support vector regression (SVR), ensemble trees (ET), Gaussian process regression (GPR), artificial neural networks (ANN), recurrent neural networks (RNN), and convolutional neural networks (CNN). A comprehensive database was assembled, incorporating 50 AC mixtures, of which 25 were from the Kingdom of Saudi Arabia and 25 were from the state of Idaho, USA. This database encompasses an extensive dataset of 3,720 |E*| measurements, associated with thirteen input features representing the proposed AC mixtures’ aggregate gradations, binder characteristics, and volumetric properties. This pioneering study surpasses existing research by examining various algorithms to predict |E*| on the same dataset, applying them with different structures and individual optimization to achieve optimal performance. The developed models are evaluated based on multi-stage assessment criteria, including the accuracy and complexity performance measures and rationality based on a sensitivity analysis. The multi-stage comparative analysis results reveal that the bagging ETs, GPR with exponential kernel, and DT record the highest prediction accuracy; however, only the bagging ETs yield the highest accuracy, lowest training and testing complexity, and rational trends throughout the sensitivity analysis. The research outcome has the potential to provide pavement engineers with advanced tools for predicting |E*| and, therefore, optimizing pavement designs and rehabilitations. Doi: 10.28991/CEJ-2025-011-01-06 Full Text: PDF

Metal–organic frameworks (MOFs), a class of porous nanomaterials, have been widely used in gas adsorption-based applications due to their high porosities and chemical tunability. To facilitate the discovery of high-performance MOFs for different applications, a variety of machine learning models have been developed to predict the gas adsorption capacities of MOFs. Most of the predictive models are developed using traditional machine learning algorithms. However, the continuously increasing sizes of MOF datasets and the complicated relationships between MOFs and their gas adsorption capacities make deep learning a suitable candidate to handle such big data with increased computational power and accuracy. In this study, we developed models for predicting gas adsorption capacities of MOFs using two deep learning algorithms, multilayer perceptron (MLP) and long short-term memory (LSTM) networks, with a hypothetical set of about 130,000 structures of MOFs with methane and carbon dioxide adsorption data at different pressures. The models were evaluated using 10 iterations of 10-fold cross validations and 100 holdout validations. The MLP and LSTM models performed similarly with high prediction accuracy. The models for predicting gas adsorption at a higher pressure outperformed the models for predicting gas adsorption at a lower pressure. The deep learning models are more accurate than the random forest models reported in the literature, especially for predicting gas adsorption capacities at low pressures. Our results demonstrated that deep learning algorithms have a great potential to generate models that can accurately predict the gas adsorption capacities of MOFs.

Recent technological advancements allow deep learning to be employed in practically every aspect of life. Because deep learning techniques are so precise, they can be used in medicine to classify and detect various diseases. The coronavirus (SARSCoV2) epidemic has recently affected global health systems. One of the ways to diagnose SARSCoV2 is with a chest X-ray. This paper proposes a deep learning technique to distinguish SARSCoV2 positive and normal cases. In this study, we fine-tuned the deep learning models and hyperparameters, and the fine-tuned deep learning models performed significantly better. To classify X-ray images, we developed a system based on deep learning algorithms that includes five models: Xception, VGG19, ResNet50, DenseNet121, and Inception. We offer deep learning models and algorithms that have been trained and evaluated to support medical efforts and reduce medical staff workload when dealing with SARSCoV2. In addition, the classification model that was proposed yields positive results because it makes use of accurate classification of the SARSCoV2 disease based on medical images. Additionally, the performance of our proposed CNN classification method for medical imaging was evaluated using various edge-based neural networks. The accuracy of tertiary classification with CNN will decrease as the number of classes in the training network grows. In tertiary classification, which includes normal and SARSCoV2 positive images, the proposed model achieved a 0.9897 accuracy. The proposed algorithm achieves a high level of classification accuracy when using the DenseNet121 model for binary classification.

In an open source software development environment, it is hard to decide the number of group members required for resolving software issues. Developers generally reply to issues based totally on their domain knowledge and interest, and there are no predetermined groups. The developers openly collaborate on resolving the issues based on many factors, such as their interest, domain expertise, and availability. This study compares eight different algorithms employing machine learning and deep learning, namely—Convolutional Neural Network, Multilayer Perceptron, Classification and Regression Trees, Generalized Linear Model, Bayesian Additive Regression Trees, Gaussian Process, Random Forest and Conditional Inference Tree for predicting group size in five open source software projects developed and managed using an open source development framework GitHub. The social information foraging model has also been extended to predict group size in software issues, and its results compared to those obtained using machine learning and deep learning algorithms. The prediction results suggest that deep learning and machine learning models predict better than the extended social information foraging model, while the best-ranked model is a deep multilayer perceptron((R.M.S.E. sequelize—1.21, opencv—1.17, bitcoin—1.05, aseprite—1.01, electron—1.16). Also it was observed that issue labels helped improve the prediction performance of the machine learning and deep learning models. The prediction results of these models have been used to build an Issue Group Recommendation System as an Internet of Things application that recommends and alerts additional developers to help resolve an open issue.

Metabolic dysfunction-associated steatotic liver disease (MASLD) can progress to metabolic dysfunction-associated steatohepatitis (MASH) and liver fibrosis, contributing to a heavier global health burden. Non-invasive diagnostic tools developed using machine learning (ML) and deep learning (DL), two representative artificial intelligence algorithms, are increasingly being explored for MASH and its related fibrosis assessment. This study aimed to compare the diagnostic performance of different ML and DL models and identify the top-performing models for diagnosing MASH and associated liver fibrosis. A systematic review and meta-analysis were conducted across PubMed, Web of Science, Embase and Cochrane Library from inception to May 18, 2025. Pooled area under the receiver operator characteristic curve (AUROC) values with 95 % confidence interval (CI) were calculated. Accuracy, specificity, sensitivity, positive predictive values, and negative predictive values were also recorded. Of 4,314 studies initially identified, 106 met the inclusion criteria, with 35 studies (ML: n=28; DL: n=7) providing data for analysis. Logistic Regression and Neural Network are the most commonly algorithms applied in ML and DL, respectively. The pooled AUROCs for diagnosing MASH were 0.833 (95 %CI: 0.806-0.860) for ML models and 0.841 (95 %CI: 0.782-0.900) for DL models. Light Gradient Boosting Machine (LightGBM) and ResNet50 were the best-performing models for diagnosing MASH within ML and DL algorithms, respectively, achieving corresponding AUROCs of 0.920 (95 %CI: 0.916-0.924) and 0.960 (95 %CI: 0.951-0.969). For fibrosis diagnosis, ML models had a pooled AUROC of 0.826 (95 %CI: 0.792-0.860), with Categorical Boosting (CatBoost) achieving the highest AUROC of 0.960 (95 %CI: 0.950-0.970). DL models yielded the pooled AUROC of 0.875 (95 %CI: 0.816-0.934) for fibrosis diagnosis. Both ML and DL models demonstrated strong diagnostic performance for MASH and liver fibrosis, with DL achieving marginally higher AUROCs. AI-driven approaches show promise in MASLD management.

COVID-19 is highly infectious and causes acute respiratory disease. Machine learning (ML) and deep learning (DL) models are vital in detecting disease from computerized chest tomography (CT) scans. The DL models outperformed the ML models. For COVID-19 detection from CT scan images, DL models are used as end-to-end models. Thus, the performance of the model is evaluated for the quality of the extracted feature and classification accuracy. There are four contributions included in this work. First, this research is motivated by studying the quality of the extracted feature from the DL by feeding these extracted to an ML model. In other words, we proposed comparing the end-to-end DL model performance against the approach of using DL for feature extraction and ML for the classification of COVID-19 CT scan images. Second, we proposed studying the effect of fusing extracted features from image descriptors, e.g., Scale-Invariant Feature Transform (SIFT), with extracted features from DL models. Third, we proposed a new Convolutional Neural Network (CNN) to be trained from scratch and then compared to the deep transfer learning on the same classification problem. Finally, we studied the performance gap between classic ML models against ensemble learning models. The proposed framework is evaluated using a CT dataset, where the obtained results are evaluated using five different metrics The obtained results revealed that using the proposed CNN model is better than using the well-known DL model for the purpose of feature extraction. Moreover, using a DL model for feature extraction and an ML model for the classification task achieved better results in comparison to using an end-to-end DL model for detecting COVID-19 CT scan images. Of note, the accuracy rate of the former method improved by using ensemble learning models instead of the classic ML models. The proposed method achieved the best accuracy rate of 99.39%.

This study investigates the use of deep learning algorithms to predict the discharge coefficient (Cd) of contaminated multi-hole orifice flow meters with circular opening. Datasets (MHO1 and MHO2) were obtained from computational fluid dynamic simulations for two circular multi-hole orifice flow meters of different geometries. To evaluate the performance and generalization capabilities of different models, three distinct scenarios, each involving different dataset configurations and normalization techniques were designed. For each scenario, three deep learning models (feedforward neural networks, convolutional neural network, and recurrent neural network) were implemented and evaluated based on their performance metrics, including mean squared error (MSE), root mean squared error (RMSE), mean absolute error (MAE), and the coefficient of determination (R2). For all three scenarios eight models for each neural network model were developed (FFNN – four models, CNN – two models, RNN – two models). The same structure of models was used across all scenarios to ensure consistency in the evaluation process. Key input parameters include geometrical and flow variables such as β – parameter, contamination thickness, radial distance, Reynolds number, and orifice diameters. Results demonstrate the effectiveness of deep learning in accurately predicting discharge coefficient for different contamination conditions and different geometries. This study showed that deep learning models can be used for prediction of discharge coefficients for multi-hole orifice flow meters of similar geometry, based on data obtained from one orifice flow meter for different contamination parameters.

The rise and fall of artificial neural networks is well documented in the scientific literature of both computer science and computational chemistry. Yet almost two decades later, we are now seeing a resurgence of interest in deep learning, a machine learning algorithm based on multilayer neural networks. Within the last few years, we have seen the transformative impact of deep learning in many domains, particularly in speech recognition and computer vision, to the extent that the majority of expert practitioners in those field are now regularly eschewing prior established models in favor of deep learning models. In this review, we provide an introductory overview into the theory of deep neural networks and their unique properties that distinguish them from traditional machine learning algorithms used in cheminformatics. By providing an overview of the variety of emerging applications of deep neural networks, we highlight its ubiquity and broad applicability to a wide range of challenges in the field, including quantitative structure activity relationship, virtual screening, protein structure prediction, quantum chemistry, materials design, and property prediction. In reviewing the performance of deep neural networks, we observed a consistent outperformance against non-neural networks state-of-the-art models across disparate research topics, and deep neural network-based models often exceeded the "glass ceiling" expectations of their respective tasks. Coupled with the maturity of GPU-accelerated computing for training deep neural networks and the exponential growth of chemical data on which to train these networks on, we anticipate that deep learning algorithms will be a valuable tool for computational chemistry. © 2017 Wiley Periodicals, Inc.

What's New in Spine Surgery.

Objectives: Language detection is the process of identifying a language associated with a text. The proposed system aims to detect the Dravidian language that is associated with the given text using different machine learning and deep learning algorithms. The paper presents an empirical analysis of the results obtained using the different models. It also aims to evaluate the performance of a language agnostic model for the purpose of language detection. Method: An empirical analysis of Dravidian language identification in social media text using machine learning and deep learning approaches with k-fold cross validation has been implemented. The identification of Dravidian languages, including Tamil, Malayalam, Tamil Code Mix, and Malayalam Code Mix, is performed using both machine learning (ML) and deep learning algorithms. The machine learning algorithms used for language detection are Naive Bayes (NB), Multinomial Logistic Regression (MLR), Support Vector Machine (SVM), and Random Forest (RF). The supervised Deep Learning (DL) models used include BERT, mBERT and language agnostic models. Findings: The language agnostic model outperform all other models considering the task of language detection in Dravidian languages. The results of both the ML and DL models are analyzed empirically with performance measures like accuracy, precision, recall, and f1-score. The accuracy associated with different machine learning algorithms varies from 85% to 89%. It is evident from the experimental result that the deep learning model outperformed with an accuracy of 98%. Novelty: The proposed system emphasizes on the use of the language agnostic model to implement the process of detecting Dravidian languages associated with the given text which provides a promising result of 98% accuracy which is higher than the existing methodologies. Keywords: Language, Machine learning, Deep learning, Transformer model, Encoder, Decoder

PurposeTo develop machine learning (ML) and deep learning (DL) models to predict glaucoma surgical outcomes, including postoperative intraocular pressure, use of ocular antihypertensive medications, and need for repeat surgery.MethodsWe identified glaucoma surgeries performed at Stanford from 2013–2024, with two or more postoperative visits with intraocular pressure (IOP) measurement. Patient features were identified from the electronic health record (EHR), including demographics, prior diagnosis and procedure codes, medications and eye exam findings. Classical ML and DL models were developed to predict which glaucoma surgeries would result in surgical failure, defined as (1) IOP not reduced by more than 20% of preoperative baseline on two consecutive postoperative visits, (2) increased classes of glaucoma medications, and (3) need for additional glaucoma surgery or revision of original surgery.ResultsA total of 2398 glaucoma surgeries of 1571 patients were included, of which 1677 surgeries met failure criteria. Random forest performed best for prediction of overall surgical failure, with accuracy of 75.5% and area under the receiver operator curve (AUROC) of 76.7%, similar to the deep learning model (accuracy 75.5%, AUROC 76.6%). Across all models, prediction performance was better for IOP outcomes (AUROC 86%) than need for an additional surgery (AUROC 76%) or need for additional glaucoma medication (AUC 70%).ConclusionsML and DL algorithms can predict glaucoma surgery outcomes using structured data inputs from EHRs.Translational RelevanceModels that predict outcomes of glaucoma surgery may one day provide the basis for clinical decision support tools supporting surgeons in personalizing glaucoma treatment plans.

Electricity load forecasting is a crucial undertaking within all the deregulated markets globally. Among the research challenges on a global scale, the investigation of deep transfer learning (DTL) in the field of electricity load forecasting represents a fundamental effort that can inform artificial intelligence applications in general. In this paper, a comprehensive study is reported regarding day-ahead electricity load forecasting. For this purpose, three sequence-to-sequence (Seq2seq) deep learning (DL) models are used, namely the multilayer perceptron (MLP), the convolutional neural network (CNN) and the ensemble learning model (ELM), which consists of the weighted combination of the outputs of MLP and CNN models. Also, the study focuses on the development of different forecasting strategies based on DTL, emphasizing the way the datasets are trained and fine-tuned for higher forecasting accuracy. In order to implement the forecasting strategies using deep learning models, load datasets from three Greek islands, Rhodes, Lesvos, and Chios, are used. The main purpose is to apply DTL for day-ahead predictions (1–24 h) for each month of the year for the Chios dataset after training and fine-tuning the models using the datasets of the three islands in various combinations. Four DTL strategies are illustrated. In the first strategy (DTL Case 1), each of the three DL models is trained using only the Lesvos dataset, while fine-tuning is performed on the dataset of Chios island, in order to create day-ahead predictions for the Chios load. In the second strategy (DTL Case 2), data from both Lesvos and Rhodes concurrently are used for the DL model training period, and fine-tuning is performed on the data from Chios. The third DTL strategy (DTL Case 3) involves the training of the DL models using the Lesvos dataset, and the testing period is performed directly on the Chios dataset without fine-tuning. The fourth strategy is a multi-task deep learning (MTDL) approach, which has been extensively studied in recent years. In MTDL, the three DL models are trained simultaneously on all three datasets and the final predictions are made on the unknown part of the dataset of Chios. The results obtained demonstrate that DTL can be applied with high efficiency for day-ahead load forecasting. Specifically, DTL Case 1 and 2 outperformed MTDL in terms of load prediction accuracy. Regarding the DL models, all three exhibit very high prediction accuracy, especially in the two cases with fine-tuning. The ELM excels compared to the single models. More specifically, for conducting day-ahead predictions, it is concluded that the MLP model presents the best monthly forecasts with MAPE values of 6.24% and 6.01% for the first two cases, the CNN model presents the best monthly forecasts with MAPE values of 5.57% and 5.60%, respectively, and the ELM model achieves the best monthly forecasts with MAPE values of 5.29% and 5.31%, respectively, indicating the very high accuracy it can achieve.