Droplet detachment in cross-flow membrane emulsification: Comparison among torque- and force-based models

Droplet formation in a T-shaped microchannel junction: A model system for membrane emulsification

Micro and nano polycaprolactone particles preparation by pulsed back-and-forward cross-flow batch membrane emulsification for parenteral administration

Status of cross-flow membrane emulsification and outlook for industrial application

Monodisperse colloidal particles of polystyrene-b-polybutadiene (PS-b-PB) block copolymers (BCPs) were successfully prepared, in which uniform emulsions containing BCPs were first generated by cross-flow membrane emulsification using tubular Shirasu porous glass (SPG) membrane, and then unique internal nanostructures were developed by controlled evaporation of solvent inside emulsion. The diameter of those BCP particles could be controlled from 200 nm to 5 μm by tuning the pore diameter of the membrane. With symmetric BCPs, onion-like nanostructures inside particles were formed. Coiled cylinders in the BCP particles were also developed by adding homopolymers, in which the assembled BCP structure is strongly dependent on the particle size, demonstrating the importance of our membrane method in generating monodisperse BCP particles. Further investigation of process parameters showed that for a given pore diameter, the operation pressure (P) and surfactant concentration were critical parameters for narrow si...

The membrane emulsification process is attracting great interest in many industrial fields. For optimization and scaling up of the emulsification process, controlling the emulsion uniformity using monitoring process and membrane parameters is especially important. In this study, the effects of phase physical property (viscosity, interfacial tension), and operation conditions (trans-membrane pressure shear stress), on droplet size distribution of an oil-in-water (o/w) emulsion were systemically investigated by membrane emulsification experiments with a cross-flowing continuous phase. Inspired by the idea that droplet spontaneous formation is one of the most important mechanisms to form a uniform emulsion, a simple model based on torque balance equations by describing the variable force torques on droplet formation process was proposed to predict experimental tendencies. The experiment phenomena showed a good coincidence with model prediction. The following experiment conditions were found to facilitate the production of uniform droplets: (1) low cross-flow velocity of the continuous phase, (2) low transmembrane pressure, (3) high viscosity of the dispersed phase, and (4) an emulsifier with great ability and rapid rate to decrease interfacial tension. © 2008 American Chemical Society.

On the estimation of the leaked volume of an oil droplet undergoing breakup in crossflow filtration: CFD investigation, scaling, and a macroscopic model

Integrated membrane emulsification and solution cooling crystallization to obtain a narrow and predictable crystal size distribution

<div class="section abstract"><div class="htmlview paragraph">The improvement of vehicle soiling behavior has increasing interest over the past few years not only to satisfy customer requirements and ensure a good visibility of the surrounding traffic but also for autonomous vehicles, for which soiling investigation and improvement are even more important due to the demands of the cleanliness and induced functionality of the corresponding sensors. The main task is the improvement of the soiling behavior, i.e., reduction or even prevention of soiling of specific surfaces, for example, windows, mirrors, and sensors. This is mostly done in late stages of vehicle development and performed by experiments, e.g., wind tunnel tests, which are supplemented by simulation at an early development stage. Among other sources, the foreign soiling on the side mirror and the side window depend on the droplet detaching from the side mirror housing. That is why a good understanding of the droplet formation process and the resulting droplet diameters behind the side mirror is necessary, including all the possible influencing factors. A first fundamental study was already investigated by the authors at a vehicle side mirror using a modified wind tunnel soiling test rig [<span class="xref">1</span>].</div><div class="htmlview paragraph">In the current study, a generic plate with a defined edge for droplet detachment is placed inside the open jet of a calibration wind tunnel. The aim of the investigation is to test different parameters of the detachment process and to analyze the resulting droplet sizes behind the generic edge. Parameters such as the radius of the detachment edge, the liquid, and the volumetric flow rate are varied and their influence on the atomization as well as soiling processes is analyzed using shadowgraphy measuring technique and high-speed video recording.</div><div class="htmlview paragraph">Our results show that the droplet detachment behind a generic plate can be divided into two separate topics: the detachment position and the detachment process. The detachment position is dependent on the air velocity and the edge radius. With an increased radius and an increased velocity, the water can stay longer wall-bound and detach further downstream. The detachment process at the edge shows two different ligament formation processes independent of the air velocity: ligament formation and ligament-bag formation. A secondary breakup process may occur for droplets in the air, where four different processes are observed, covering vibration breakup, bag breakup, bag-and-stamen breakup, and sheet thinning. In all tested variations, most of the droplets show a diameter of about 65 μm.</div></div>

Additive manufacturing is driving major innovations in many areas such as biomedical engineering. Recent advances have enabled 3D printing of biocompatible materials and cells into complex 3D functional living tissues and organs using bioink. Inkjet-based bioprinting fabricates the tissue and organ constructs by ejecting droplets onto a substrate. Compared with microextrusion-based and laser-assisted bioprinting, it is very difficult to predict and control the droplet formation process (e.g., droplet velocity and size). To address this issue, this paper presents a new data-driven approach to predict droplet velocity and size in the inkjet-based bioprinting process. An imaging system was used to monitor the droplet formation process. To investigate the effects of excitation voltage, dwell time, and rise time on droplet velocity and droplet size, a full factorial design of experiments was conducted. Two predictive models were developed to predict droplet velocity and droplet size using random forests. The accuracy of the two predictive models was evaluated using the relative error. Experimental results have shown that the predictive models are capable of predicting droplet velocity and size with sufficient accuracy.

A multiphysics model for charged liquid droplet breakup in electric fields

Microdroplet formation in microfluidic systems plays a pivotal role in chemical engineering, biomedicine, and energy applications. Precise control over the droplet size and formation dynamics of microdroplets is essential for optimizing performance in these fields. This work explores a hybrid control strategy that combines an active electric field with passive rib structures to regulate the droplet formation in a ribbed T-junction microchannel under an electric field. Numerical simulations based on the phase-field method are employed to analyze the effects of the electric capillary number and rib height on the droplet formation mechanism. The results reveal that increasing induces three distinct flow regimes of the dispersed phase: unpinning, partially pinning, and fully pinning regimes. This transition from an unpinning to a pinning regime increases the contact area between the wall and dispersed phase, restricts the flow of the continuous phase, and induces the shear stress of the wall, leading to a reduction in droplet size with the enhanced . Furthermore, an increase in rib height enhances the shear stress of the continuous phase above the rib, causing a progressive shift from a fully pinning to an unpinning regime, which results in a linear decrease in droplet size. A new empirical correlation is proposed to predict droplet size as a function of rib height and two-phase flow rate ratio : .

Microfluidic systems are an interesting topic for investigation due to their wide-spreading applications. Nowadays, polymeric solutions are used mainly for the generation of microparticles in biomedical engineering, food, and pharmaceutical industries. Droplet-based microfluidic devices have proposed an extensive interest in many applications such as chemical/biological/nanomaterial preparation to understand deeply the droplet size and formation in microchannels. However, numerous experimental and numerical studies have been done for oil–water combination, polymeric solutions behavior in the presence of oil has not been investigated widely. Therefore, it is important to understand the droplet formation mechanisms in a microfluidic device for both water and polymeric solutions to determine the flow regime mapping in order to control the characteristic of the produced droplets. Also, in many studies, the length of the droplets as a parameter to investigate the droplet size was studied. In this study, droplet generation in the T-shaped microfluidic junction with an enlarged horizontal outlet channel was studied to have opportunity to determine the diameter of spherical droplets. The water and the alginate 1% (w/v) solutions were used separately as a dispersed phase, and the mineral oil was used as the continuous phase in which the solution's flow rates were varied over a wide range. To perform numerical simulations of the droplet formation, a two-phase level set method was used which is a suitable method for the investigation and simulation of immiscible fluids. The flow regime mapping for the two different aqueous solutions was obtained. Furthermore, the influences of flow rates on droplet size, droplet generation frequency was quantified. In this study, flow regime, droplet size, and droplet frequency were studied. In general, flow rates of the oil and aqueous fluids readily control five main flow regimes including backflow, laminar flow, dripping flow, squeezing flow, jetting flow, and fluctuated flow. It was observed that generated droplets with alginate solution as dispersed phase were more in the region of the jetting flow regime while water droplets were more in the region of the dripping flow regime, this can be due to the difference in characteristics of polymeric solution and water. For both aqueous phases, larger droplets were obtained when flow rates of oil were decreased and aqueous phases were increased. Also, the frequency of droplet generation increases and decreases by increasing oil phase flow rate and increasing aqueous phase flow rate, respectively. In the same flow rates of aqueous phase and oil, the sizes of water droplets are larger than the alginate droplets and also water has a higher frequency of droplet generation compared to alginate. Finally, we characterized all the obtained data for flow regimes due to the capillary number (Ca) of the continuous phase. The findings of this study can help for better understanding of the detailed process of droplet generation of water and alginate solution as dispersed phase separately with mineral oil as the continuous phase in a T-junction geometry microfluidic and know the effect of characteristics of solutions as a dispersed flow in flow regimes.

The shedding kinematics of water droplets in a condensation environment when exposed to aerodynamic forces in microgravity was studied. Understanding the shedding of droplets from a surface is a critical part of the dropwise condensation process for improving heat transfer. Because gravity as a droplet removal technique is not available in space, the use of airflow to shed droplets is considered for condensing heat exchangers in environmental control and life support systems. Surface coatings affect drop adhesion, and here, four different surfaces (PMMA, PS, PTFE, and SHS) and various droplet sizes (80, 60, and 40 μL) were used to understand the above phenomenon. It was found that the critical velocity to shed a droplet in microgravity was up to 8% lower than that in normal gravity. Also, the effect of the droplet size was investigated for both microgravity and normal gravity; the shedding velocity was lower for microgravity, and it decreased as droplet size increased. Increasing the hydrophobicity of the coating decreased the critical velocity for shedding. Finally, the droplet was found to detach from superhydrophobic surfaces in microgravity. The detachment of droplets from the substrate will hamper the condensation process that can produce a larger fresh area; also, detachment of droplets and entrainment in airflow counter the concept of removing moisture from the air in a dehumidification process.

Preparation of water-in-oil and ethanol-in-oil emulsions by membrane emulsification

Hydrodynamics of Liquid Jet Application in High-Speed Jet Coating: Newtonian and Shear-thinning Fluids