Dynamic titanium prosthesis based on 3D-printed replica for chest wall resection and reconstruction

ABSTRACTBackground:Dental implants have been essential to the therapy of patients who are partially edentulous.Aim:Clinical evaluation of the long-term survival and success rates of different types of implant-supported prostheses.Materials and Methods:Patients who had a healthy edentulous ridge of three missing teeth in the posterior jaw in which two or three dental implants were placed having any of three prostheses, namely, three-unit fixed dental prostheses (FPD) on two implants, three splinted crowns on three implants, and three splinted crowns on three implants were included.Results:The survival rate in all patients with dental implants having different types of prostheses was 94.9%. The survival rate in FPD, three splinted crowns, and three nonsplinted crowns was 100, 88.5, and 93.6% respectively.Conclusion:FPD loaded on two dental implants was found to have a greater long-term survival rate and success rate with a lower frequency of peri-implantitis and prosthodontic complications.

P3.04-037 Rare Giant Malignant Tumors of the Chest: Reconstructive Challenge: Topic: Miscellaneous II

Tricuspid valve replacement: Postoperative and long-term results

Complications in Wound Healing after Chest Wall Resection in Cancer Patients; a Multivariate Analysis of 220 Patients

Video-Assisted Thoracic Surgery Technique for Chest Wall Resection

Symposium

Large chest wall defects, as a result of wide local excision of chest wall pathology, require skeletal and soft-tissue reconstruction to restore the anatomical shape, structure, and respiratory function of the thorax. Reconstruction is challenging and requires the surgical reconstructive team to understand the anatomic and physiologic morbidity related to the defect and the choice of reconstructive techniques available to restore form and function. Rapidly emerging 3-dimensional (3D) printing technology allows the reconstructive surgical team to customize the therapeutic process of skeletal reconstruction by accurately mimicking the shape and structure of the chest wall being replaced. An integrated knowledge of the anatomy, physiology, mechanics of breathing, and respiratory tests is important to restore form and function. The focus of this article is to review the anatomy, physiology, and assessment of respiratory function from the classical textbooks and integrate this knowledge with the precise anatomy of the chest wall created by 3D printing technology. By doing so, this article will demonstrate how 3D printing may help the reconstructive team to understand the anatomic and physiologic morbidity related to the chest wall defect and the importance of taking each of these aspects into consideration when undertaking chest wall reconstruction of the thorax.

Different total knee arthroplasty （TKA） designs showed different intra-operative kinematics when evaluated with a navigation system. This study compared the kinematics of three different prosthesis designs using navigation-based in vivo simulation. Studies were carried out on 18 osteoarthritic knees using a computed tomography （CT）-free navigation system. The TKA designs used for these patients were six each of cruciate-retaining （CR） type, posterior-stabilized （PS） type, and PS mobile type. Intraoperative knee kinematics were measured during a passive range of motion from full extension to 130 degrees of knee flexion. Three types of prosthesis were compared for the following factors: the presence of condylar lift-off （gap difference greater than 1mm between medial gap and lateral gap） and anterior-posterior （AP） displacement of the center of femur relative to the tibia. The lift-off was found in patients with the PS type between 120° and 130° of flexion, but not in the other two types of implant. The pattern of AP displacement was similar among the three implants. The femur moved to the anterior side from extension to 50-55° of flexion, after that, the femur moved to the posterior side to full flexion. The function of PCL could prevent lift-off in the CR type of implants. In the PS-mobile implants, the mechanism of rotation platform might have contributed to lift-off prevention. The paradoxical anterior slide of the femoral condyles during mid flexion was observed in all types of implant.

본 연구는 보철물 장착 환자의 구강 내 C. albicans 분포에 대한 연구로 구강 Candida 감염증의 주 원인균인 C. albicans의 분포를 측정한 후 감염 위험정도의 분석을 통해 보철물 장착 환자들에게 구강건강관리의 중요성에 대한 자료로 제공하고자 연구대상자의 성별, 흡연 및 음주유무, 구강 내 보철물 종류 및 장착 기간, 1일 칫솔질 횟수에 따른 C. albicans 집락 정도를 조사하였다. 연구대상자들 중 11.6%에서 감염 1단계 이상의 분포를 보여 구강 Candida 감염 가능성을 확인하였다. 또한 타액 채취 부위별 C. albicans 분포를 분석한 결과 상악보다 하악의 설면에서, 입천장보다 혀 등이 상대적으로 높은 단계의 분포를 보였다. 성별, 흡연 및 음주유무에 따른 C. albicans 분포는 여자보다 남자가, 흡연을 하는 경우보다 흡연을 하지 않는 경우가, 음주를 하지 않는 경우보다 음주를 하는 경우에 구강 Candida 감염 단계 평균 수치가 높게 나타났다. C. albicans의 단계별 분포는 구강 Candida 감염 3단계의 분포가 여자는 관찰되지 않았지만 남자는 1.4%의 분포가 관찰되었으며, 구강 Candida 감염 2단계 이상의 분포가 흡연 및 음주를 하는 경우에는 관찰되지 않았지만 하지 않는 경우에는 각각 3.3%, 3.6%의 분포가 관찰되었다. 구강 내 보철물 중 가철성 교정장치보다 의치 혹은 임플란트를 장착한 경우 C. albicans의 분포에 더 영향을 미치고 있으며, 보철물을 1년 이상 장착한 경우에 기간이 길어질수록 구강 Candida 감염 1단계 이상의 분포가 점점 높아졌다. 단, 7~9년 장착한 경우에는 100.0%의 0단계의 분포를 보였다. 1일 칫솔질 횟수에 따른 구강 Candida 감염 단계 평균 수치를 통해 구강위생관리와 C. albicans의 분포의 상관관계를 확인하고자 하였으나 칫솔질 횟수는 직접적으로 작용하지 않는 것으로 보였다. 이상의 결과로 볼 때 보철물 장착 환자의 성별, 구강 내 부위, 보철물 종류, 보철물 장착 기간이 구강 내 C. albicans의 분포에 영향을 미치고 있는 것으로 나타났다. 향후 관련된 여러 요인들을 모두 추가, 보완하거나 다각적으로 검토하여 심도 있는 연구를 통해 구강건강을 유지 및 증진시킬 수 있는 자료를 확보하는 것이 필요하다고 생각된다. Of the many pathogenic Candida species, Candida albicans is the main fungal pathogen of humans. The oral environmental factors considered in the Candida albicans colony forming unit test contain both host and microbial factors associated with candidiasis. In particular, Candida biofilms can develop on surfaces of prosthesis. The purpose of this study was to investigate the distribution of oral Candida species between the type of prosthesis and the situation of oral environment in patient with prosthetic appliance. The patients were 30 elderly subjects with different types of prosthesis, 7 who wore denture, 12 who wore implant and 15 who wore removable orthodontic appliance. We used Candida albicans colony forming unit test using saliva to exam the distribution of Candida albicans related with 5 oral environmental factors, gender, smoking or nonsmoking, alcohol/nonalcohol consumption, the type of prosthetic appliance and its treatment duration as well as tooth brushing frequency per day. In conclusion, for the patient's gender, site in the oral cavity and the type of prosthetic appliance and its treatment duration was associated with an increase in the distribution of Candida albicans in saliva. The distribution of Candida albicans within the oral cavity performs to be modulated to varying extents by oral environmental factors and, further investigations are required to elucidate these complex interactions.

The effective incidence of cutaneous squamous cell carcinoma of the skin (cSCC) is unknown, in general cSCC is the second most common skin cancer, accounting for 20% of all cutaneous malignancies, with a continuous increase in its frequency (1). The skin of the thorax is a very rare localization for this kind of tumor (1-4). Despite cSCC is a malignant proliferation of keratinizing cells of the epidermis, generally, when the diagnosis is made, early surgical resection with adequate surgical margins is curative in more than 95% of the cases (5). Here we present a very rare case of local recurrence of a huge cSCC involving the anterior chest wall that underwent extensive chest wall resection associated to complex reconstruction by using a combination of synthetic materials and autologous flaps.

Extensive chest wall resection, reconstruction and right pneumonectomy in a 24-week pregnant patient

Chest wall reconstruction plays an important role in the outcomes of chest wall resection. However, there being a huge variety of materials at disposable, the best option has not yet been well defined. The Vitagraft® is a synthetic and absorbable material, that works as an osteoinduction and osteoconduction for bone regeneration. It consists of a β-phase Tricalcium Phosphate Ceramic (β-TCP) and the Polylactic Glycolic Acid Polymer (PLGA). Therefore, this study intends to assess the safety of Vitagraft® use in the chest wall. A prospective study, in which the patient's chest was reconstructed with Vitagraft®. Each patient was followed after the procedure for at least three months. The following variables were considered: KPS, ECOG, preoperative treatment, defect size, myocutaneous flap, the time between surgeries, complications, and mortality. Eight resections were performed due to tumor findings. One reconstruction was a treatment for sternal cleft, another for Poland's syndrome, and finally as a consequence of late sternal dehiscence. Primary closure was performed in 63.6 % of the patients. Vitagraft® was used in association with mesh in eight cases. Reoperation was required in two cases, and prosthesis removal for one of them. Respiratory failure and major systemic complications were not evidenced. In the present study, the first to assess Vitagraft® in chest wall reconstruction, the second operation was necessary for 28 %, and removal was mandatory for 14 %. Until now, chest postoperative tomography has been showing good prosthesis biocompatibility. The authors need further details about the ossification time especially relating to the size of the resection.

ObjectiveMalignant chest wall tumors are rare neoplasms. Resection with wide-free margins is an important prognostic factor, and massive chest wall resection and reconstruction are often necessary. A recent case series of 20 consecutive patients is reported in order to find any possible correlation between tumor histology, extent of resection, type of reconstruction, and adjuvant treatment with short- and long-term outcomes.MethodsTwenty patients were submitted to chest wall resection and reconstruction for malignant chest wall neoplasms between 2006 and 2014. The mean age (ten males) was 59±4 years. The size and histology of the tumor, the technique of reconstruction, and the short- and long-term follow-up records were noted.ResultsThe median maximum diameter of tumors was 10 cm (5.4–32 cm). Subtotal sternal resection was performed in nine cases, and the resection of multiple ribs was performed in eleven cases. The median area of chest wall defect was 108 cm2 (60–340 cm2). Histology revealed soft tissue, bone, and cartilage sarcomas in 16 cases (80%), most of them chondrosarcomas. The rest of the tumors was metastatic tumors in two cases and localized malignant pleural mesothelioma and non-Hodgkin lymphoma in one case. The chest wall defect was reconstructed by using the “sandwich technique” (propylene mesh/methyl methacrylate/propylene mesh) in nine cases of large anterior defects or by using a 2 mm polytetrafluoroethylene (e-PTFE) mesh in nine cases of lateral or posterior defects. Support from a plastic surgeon was necessary to cover the full-thickness chest wall defects in seven cases. Adjuvant oncologic treatment was administered in 13 patients. Local recurrences were observed in five cases where surgical reintervention was finally necessary in two cases. Recurrences were associated with larger tumors, histology of malignant fibrous histiocytoma, and initial incomplete resection or misdiagnosis made by nonthoracic surgeons. Three patients died during the study period because of recurrent disease or complications of treatment for recurrent disease.ConclusionChest wall tumors are in their majority mesenchymal neoplasms, which often require major chest wall resection for their eradication. Long-term survival is expected in low-grade tumors where a radical resection is achieved, while big tumors and histology of malignant fibrous histiocytoma are connected with the increase rate of recurrence.

Background: The wrist is essential for augmentation of fine motor control of the hand and fingers. The normal wrist motion involves a complex interaction of articulations from the radius, ulna and carpal bones. Hence, when a disease process disrupts any one of these elements, a painful, deformed and dysfunctional wrist arises. Total wrist arthroplasty is considered an alternative surgical option to wrist fusion for the management of advanced wrist arthritic diseases. Though less commonly performed in comparison to lower‐limb arthroplasty, wrist arthroplasty has its role as a salvage procedure to alleviate pain and preserve function in the wrists.Method: Four patients were collected from the Centre of Hand Surgery, Sydney. Medical records of these patients were reviewed. The patient's pre‐and post‐operative functional status via clinical and radiographic assessments were closely followed over an average period of five years to ensure the continuity of progress. A table was formulated to provide an objective survey of both quantitative and qualitative improvement of a patient's wrist function.Result: The four patients received different types of prostheses. This is an indication of a lack of universal acceptance of wrist anatomy and biomechanics. Regardless, all patients in this study had improved functional outcomes. Pain‐relief was the most successful aspect of wrist arthroplasty during post‐operative follow‐ups. The successful outcome of these patients has proven that total wrist arthroplasty can provide pain relief and an improvement in hand function through appropriate patient selections, careful peri‐operative planning, sound operative technique and well‐designed post‐operative hand therapy.

The purpose of this paper is to report our personal experience in the field of augmentation mammoplasty. This experience is based on over 15 years in practice and working with more than 400 cases using different types of prostheses (single-lumen gel-filled, single-lumen saline-filled, double-lumen, smooth or texturized surfaces), different routes (submammary, periareolar, transaxillary), and different locations of the implant (complete submuscular, subglandular, subpectoral). Our present preference is for a partial submuscular (subpectoral) augmentation mammoplasty through an inferior periareolar route. The results of 91 consecutive patients operated on with this technique from January, 1990 to December, 1994, during the blow-up of the controversy on silicone, are reported.