EAHN Conference, Dublin June 2–5, 2016: Closing Remarks

Event Abstract Back to Event Polycyclic aromatic hydrocarbon pollution affects tissue fatty acid compositions in Holothuria scabra (Jaeger, 1833): A sea cucumber from Qeshm Island, Persian Gulf, Iran Elham Kamyab1, 2*, Julian Döring3, Aida Khazaali2 and Andreas Kunzmann2 1 Oldenburg University, Institute for chemistary and marine biology (ICBM), Germany 2 Institute for marine tropical ecology (ZMT), Germany 3 Institute for marine tropical ecology, Germany Tropical sea cucumbers like Holothuria scabra are of increasing commercial importance because of their supposedly beneficial effects on the human health. They are sensitive organisms to any (micro) contaminant accumulated in marine sediments. In spite of their important role in the ecosystem as bioturbators, their physiological performance under anthropogenic environmental pollution is not sufficiently well studied. Polycyclic aromatic hydrocarbons (PAH) in the environment mainly originate from human activities and have negative impacts on the quality of sediments and therefore also on deposit feeders. The aim of the present study was to identify the impact of PAH on the essential fatty acid (EFA) compositions in different tissues (muscle, body wall, and respiratory tree) of H. scabra. EFAs such as Arachidonic acid (20:4(n-3)), Docosahexaenoic acid (22:6(n-3)), and Eicosapentaenoic acid (20:5(n-3)) play important roles in the metabolic pathways of echinoderms and are crucial during the overall physiological performance of a species. Therefore, specimens were sampled at two different sites on Qeshm Island, Iran. At one sampling site, elevated PAH levels could be detected, whereas no PAH pollution was traceable at the other. EFA compositions differed between different tissues within both sampled populations. Also, differences in EFA compositions were observed between tissues of specimens sampled at the polluted and at the not polluted sampling site. This may reveal direct effects of PAH pollution on the benthic primary producer community and/or on the metabolic pathways in H. scabra. Understanding the effects of anthropogenic pollutants on a key species’ EFA composition and thus on its metabolism is crucial to evaluate the impact of man-made pollution on marine ecosystems. Keywords: Fatty Acids, DHA, EPA, PAH, Iran, metabolic pathway, Anthropogenic pollution Conference: IMMR | International Meeting on Marine Research 2016, Peniche, Portugal, 14 Jul - 15 Jul, 2016. Presentation Type: Oral presentation Topic: Biodiversity, Conservation and Coastal Management Citation: Kamyab E, Döring J, Khazaali A and Kunzmann A (2016). Polycyclic aromatic hydrocarbon pollution affects tissue fatty acid compositions in Holothuria scabra (Jaeger, 1833): A sea cucumber from Qeshm Island, Persian Gulf, Iran. Front. Mar. Sci. Conference Abstract: IMMR | International Meeting on Marine Research 2016. doi: 10.3389/conf.FMARS.2016.04.00104 Copyright: The abstracts in this collection have not been subject to any Frontiers peer review or checks, and are not endorsed by Frontiers. They are made available through the Frontiers publishing platform as a service to conference organizers and presenters. The copyright in the individual abstracts is owned by the author of each abstract or his/her employer unless otherwise stated. Each abstract, as well as the collection of abstracts, are published under a Creative Commons CC-BY 4.0 (attribution) licence (https://creativecommons.org/licenses/by/4.0/) and may thus be reproduced, translated, adapted and be the subject of derivative works provided the authors and Frontiers are attributed. For Frontiers’ terms and conditions please see https://www.frontiersin.org/legal/terms-and-conditions. Received: 19 May 2016; Published Online: 13 Jul 2016. * Correspondence: Ms. Elham Kamyab, Oldenburg University, Institute for chemistary and marine biology (ICBM), Wilhemshaven, Germany, elham.kamyab@zmt-bremen.de Login Required This action requires you to be registered with Frontiers and logged in. To register or login click here. Abstract Info Abstract The Authors in Frontiers Elham Kamyab Julian Döring Aida Khazaali Andreas Kunzmann Google Elham Kamyab Julian Döring Aida Khazaali Andreas Kunzmann Google Scholar Elham Kamyab Julian Döring Aida Khazaali Andreas Kunzmann PubMed Elham Kamyab Julian Döring Aida Khazaali Andreas Kunzmann Related Article in Frontiers Google Scholar PubMed Abstract Close Back to top Javascript is disabled. Please enable Javascript in your browser settings in order to see all the content on this page.

Frontiers Events is a rapidly growing calendar management system dedicated to the scheduling of academic events. This includes announcements and invitations, participant listings and search functionality, abstract handling and publication, related events and post-event exchanges. Whether an organizer or participant, make your event a Frontiers Event!

Event Abstract Back to Event Factors shaping contemporary patterns of genetic diversity of the Portuguese endemic cyprinids Carla Sousa Santos1*, Joana I. Robalo1, Ana M. Pereira1, Paulo Branco2, 3, José M. Santos2, Maria T. Ferreira2, Monica Sousa4 and Ignacio Doadrio5 1 ISPA, Portugal 2 CEF—Centro de Estudos Florestais, Instituto Superior de Agronomia, Universidade de Lisboa, Portugal 3 CERis—Civil Engineering Research and Innovation for Sustainability, Instituto Superior Técnico, Portugal 4 Instituto da Conservação da Natureza e das Florestas, I.P., Portugal 5 Museo Nacional de Ciencias Naturales, CSIC, Portugal Iberian cyprinids are currently highly endangered, with over 68% of the species raising some level of conservation concern. Population declines were reported in the last decades, however, it was unknown if it was coupled with the depletion of gene pools. In order to assess the genetic diversity distribution patterns of native cyprinid species, the Portuguese hydrographical network was extensively covered (all the 34 river basins and 47 sub-basins). A total of 188 populations belonging to 16 cyprinid species of Squalius, Luciobarbus, Achondrostoma, Iberochondrostoma, Anaecypris and Pseudochondrostoma were characterized, for a total of 3,678 cytochrome b gene sequences. We found differences among populations from the same species and between species with identical distribution areas. Factors shaping the contemporary patterns of genetic diversity were explored and the results revealed the role of latitude, inter-basin connectivity, migratory behaviour, species maximum size, species range and other species intrinsic traits in determining the genetic diversity of sampled populations. Contrastingly, drainage area and hydrological regime (permanent vs. temporary) seem to have no significant effect on genetic diversity. Species intrinsic traits, maximum size attained, inter-basin connectivity and latitude explained over 30% of the haplotype diversity variance and, generally, the levels of diversity were significantly higher for smaller sized species, from connected and southerly river basins. Keywords: Haplotype diversity, Nucleotide diversity, fish conservation, Genetic diversity drivers, Endangered Species Conference: IMMR | International Meeting on Marine Research 2016, Peniche, Portugal, 14 Jul - 15 Jul, 2016. Presentation Type: Poster presentation Topic: Biodiversity, Conservation and Coastal Management Citation: Sousa Santos C, Robalo JI, Pereira AM, Branco P, Santos JM, Ferreira MT, Sousa M and Doadrio I (2016). Factors shaping contemporary patterns of genetic diversity of the Portuguese endemic cyprinids. Front. Mar. Sci. Conference Abstract: IMMR | International Meeting on Marine Research 2016. doi: 10.3389/conf.FMARS.2016.04.00072 Copyright: The abstracts in this collection have not been subject to any Frontiers peer review or checks, and are not endorsed by Frontiers. They are made available through the Frontiers publishing platform as a service to conference organizers and presenters. The copyright in the individual abstracts is owned by the author of each abstract or his/her employer unless otherwise stated. Each abstract, as well as the collection of abstracts, are published under a Creative Commons CC-BY 4.0 (attribution) licence (https://creativecommons.org/licenses/by/4.0/) and may thus be reproduced, translated, adapted and be the subject of derivative works provided the authors and Frontiers are attributed. For Frontiers’ terms and conditions please see https://www.frontiersin.org/legal/terms-and-conditions. Received: 28 Apr 2016; Published Online: 13 Jul 2016. * Correspondence: PhD. Carla Sousa Santos, ISPA, Lisboa, Portugal, csousasantos@gmail.com Login Required This action requires you to be registered with Frontiers and logged in. To register or login click here. Abstract Info Abstract The Authors in Frontiers Carla Sousa Santos Joana I Robalo Ana M Pereira Paulo Branco José M Santos Maria T Ferreira Monica Sousa Ignacio Doadrio Google Carla Sousa Santos Joana I Robalo Ana M Pereira Paulo Branco José M Santos Maria T Ferreira Monica Sousa Ignacio Doadrio Google Scholar Carla Sousa Santos Joana I Robalo Ana M Pereira Paulo Branco José M Santos Maria T Ferreira Monica Sousa Ignacio Doadrio PubMed Carla Sousa Santos Joana I Robalo Ana M Pereira Paulo Branco José M Santos Maria T Ferreira Monica Sousa Ignacio Doadrio Related Article in Frontiers Google Scholar PubMed Abstract Close Back to top Javascript is disabled. Please enable Javascript in your browser settings in order to see all the content on this page.

Frontiers Events is a rapidly growing calendar management system dedicated to the scheduling of academic events. This includes announcements and invitations, participant listings and search functionality, abstract handling and publication, related events and post-event exchanges. Whether an organizer or participant, make your event a Frontiers Event!

Event Abstract Back to Event Disentangling biological variables affecting population structure and genetic connectivity Sara M. Francisco1*, Ana M. Pereira1 and Joana I. Robalo1 1 Instituto Universitário de Ciências Psicológicas, Sociais e da Vida, MARE—Marine and Environmental Sciences Centre, Portugal Evaluating and understanding the evolutionary dynamics of divergent populations is of paramount importance for both fisheries management and conservation strategies. Nevertheless, direct measurement of marine organisms’ dispersal capabilities can be highly challenging at broad spatial scales. Despite the traditional use of genetic approaches to quantify demographic connectivity, the difficulty to distinguish contemporary from historical connectivity remains. In this study, we aim to disentangle the various biological factors affecting population structure in marine fishes from the Northeastern Atlantic. This work included most of the phylogeography studies available in scientific search engines, encompassing a wide geographical area and using both genetic and genomic data. We did a meta-analysis using exploratory factorial followed by several regression analyses to reveal potential emerging patterns. The fixation index (FST) obtained in the literature was compared against several independent biogeographical, ecological and life-history variables. Despite the lack of available data for several parameters, our results refute general expectations, conventional wisdom and several papers, that PLD and early life-history traits are good predictors of population structure in marine organisms. In fact, the Type of Genetic Marker (mitochondrial, nuclear, microsatellite) and Adult Ability to Dispersal (weak, good or strong) were found to be determinant for significant FST and population structure. These results point to the need of future intercomparable studies with larger species numbers and including marine organisms with distinct life-history traits, which would significantly enrich the present approach and have a huge potential for marine protected areas design and management. Keywords: population structure, Genetic connectivity, fish, Northeastern Atlantic, Meta-analysis Conference: IMMR'18 | International Meeting on Marine Research 2018, Peniche, Portugal, 5 Jul - 6 Jul, 2018. Presentation Type: Poster Presentation Topic: Biodiversity, Conservation and Coastal Management Citation: Francisco SM, Pereira AM and Robalo JI (2019). Disentangling biological variables affecting population structure and genetic connectivity. Front. Mar. Sci. Conference Abstract: IMMR'18 | International Meeting on Marine Research 2018. doi: 10.3389/conf.FMARS.2018.06.00139 Copyright: The abstracts in this collection have not been subject to any Frontiers peer review or checks, and are not endorsed by Frontiers. They are made available through the Frontiers publishing platform as a service to conference organizers and presenters. The copyright in the individual abstracts is owned by the author of each abstract or his/her employer unless otherwise stated. Each abstract, as well as the collection of abstracts, are published under a Creative Commons CC-BY 4.0 (attribution) licence (https://creativecommons.org/licenses/by/4.0/) and may thus be reproduced, translated, adapted and be the subject of derivative works provided the authors and Frontiers are attributed. For Frontiers’ terms and conditions please see https://www.frontiersin.org/legal/terms-and-conditions. Received: 19 Apr 2018; Published Online: 07 Jan 2019. * Correspondence: Dr. Sara M Francisco, Instituto Universitário de Ciências Psicológicas, Sociais e da Vida, MARE—Marine and Environmental Sciences Centre, Lisbon, , 1149-041, Portugal, sara_francisco@ispa.pt Login Required This action requires you to be registered with Frontiers and logged in. To register or login click here. Abstract Info Abstract The Authors in Frontiers Sara M Francisco Ana M Pereira Joana I Robalo Google Sara M Francisco Ana M Pereira Joana I Robalo Google Scholar Sara M Francisco Ana M Pereira Joana I Robalo PubMed Sara M Francisco Ana M Pereira Joana I Robalo Related Article in Frontiers Google Scholar PubMed Abstract Close Back to top Javascript is disabled. Please enable Javascript in your browser settings in order to see all the content on this page.

Frontiers Events is a rapidly growing calendar management system dedicated to the scheduling of academic events. This includes announcements and invitations, participant listings and search functionality, abstract handling and publication, related events and post-event exchanges. Whether an organizer or participant, make your event a Frontiers Event!

Event Abstract Back to Event Environmental state of an intertidal complex and anthropization in its catchment area Marta Román Geada1*, Jessica Zamborain Mason1, Emilio Fernández Suárez1 and Gonzalo Méndez Martínez1 1 University of Vigo, Spain Environmental state analysis of an intertidal complex and the study of anthropization in its associated basin were done. The purpose was to amplify the knowledge of the relationship between land occupation changes and their effect on the marine environment. The study was divided in two stages. 1: The land use changes variation area from 1990 to 2006 in the catchment was quantified by getting the data of the Corine Land Cover (CLC) satellite images and processing them by geographical information system software. Statistical data (demographic and buildings) showed the human pressures in the area. 2: A core was collected at the intertidal complex, and the sediment was subjected to granulometric analysis, also the studies of organic matter percentage, ratios of stable carbon and nitrogen isotopes, total carbon and nitrogen, and trace metals were done. The provisional results of the CLC analysis showed that the most significant land use changes in the study period were the loss of forest soil and crops and the increase of infrastructures. In the upper 68 cm of the sediment, it was found that the grain size was finer at the upper parts of the core and the organic matter percentage decreased with depth, when the gravels appeared. The δ15N values were between 4,6 and 5,7‰ and the δ13C values were between -25,5 and -24,1‰. The C/N ratio had an increasing trend with depth with a maximum of 13.1 and a minimum of 10.2, and the inorganic elements analysis showed that the concentrations of lead, copper and zinc exceeded the background concentrations for contaminants established by the OSPAR commission. Acknowledgements Cynthia Silvina Fernández Díaz Aida Ovejero Campos References Ellis, E.C.; Goldewijk, K.K.; Siebert, S.; Lightman, D. y Ramankutty, N. (2010). Antropogenic transformation of the biomes, 1700 to 2000. Global ecology and biogeography 19: 589-606. Oslo and Paris Commision (2005). Agreement on Background Concentrations for Contaminants in Seawater, Biota and Sediment (OSPAR Agreement 2005-6). Replaces OSPAR Agreement 1997-14. OSPAR Commission, London. Keywords: Estuaries, Corine Land Cover, Land use changes, Stable isotopes, Trace metals Conference: IMMR | International Meeting on Marine Research 2014, Peniche, Portugal, 10 Jul - 11 Jul, 2014. Presentation Type: Poster Presentation Topic: BIODIVERSITY, CONSERVATION AND COASTAL MANAGEMENT Citation: Román Geada M, Zamborain Mason J, Fernández Suárez E and Méndez Martínez G (2014). Environmental state of an intertidal complex and anthropization in its catchment area. Front. Mar. Sci. Conference Abstract: IMMR | International Meeting on Marine Research 2014. doi: 10.3389/conf.fmars.2014.02.00136 Copyright: The abstracts in this collection have not been subject to any Frontiers peer review or checks, and are not endorsed by Frontiers. They are made available through the Frontiers publishing platform as a service to conference organizers and presenters. The copyright in the individual abstracts is owned by the author of each abstract or his/her employer unless otherwise stated. Each abstract, as well as the collection of abstracts, are published under a Creative Commons CC-BY 4.0 (attribution) licence (https://creativecommons.org/licenses/by/4.0/) and may thus be reproduced, translated, adapted and be the subject of derivative works provided the authors and Frontiers are attributed. For Frontiers’ terms and conditions please see https://www.frontiersin.org/legal/terms-and-conditions. Received: 08 May 2014; Published Online: 18 Jul 2014. * Correspondence: Miss. Marta Román Geada, University of Vigo, Vigo, Spain, marroman@uvigo.es Login Required This action requires you to be registered with Frontiers and logged in. To register or login click here. Abstract Info Abstract The Authors in Frontiers Marta Román Geada Jessica Zamborain Mason Emilio Fernández Suárez Gonzalo Méndez Martínez Google Marta Román Geada Jessica Zamborain Mason Emilio Fernández Suárez Gonzalo Méndez Martínez Google Scholar Marta Román Geada Jessica Zamborain Mason Emilio Fernández Suárez Gonzalo Méndez Martínez PubMed Marta Román Geada Jessica Zamborain Mason Emilio Fernández Suárez Gonzalo Méndez Martínez Related Article in Frontiers Google Scholar PubMed Abstract Close Back to top Javascript is disabled. Please enable Javascript in your browser settings in order to see all the content on this page.

Event Abstract Back to Event Response to habitat-associated cues by sand smelt larvae Ana M. Faria1*, Frederico Almada1, Goncalo Silva1, Sara Martins-Cardoso1 and Emanuel J. Gonçalves1 1 MARE-ISPA, Portugal The use of sensory cues to navigate and orient to habitats has been a major research question in the field of ecological research in the last decades. Fish larvae can use a set of sensory cues to detect and discriminate between potential settlement sites. Many previous studies have shown that fish are able to respond to a variety of chemical signals, such as habitat and conspecifics, and consequently locate a critical nursery habitat. However, the use of olfactory cues for habitat selection has been mostly addressed for coral-reef fishes, with a clear lack of literature regarding the use of olfactory cues in marine, temperate fish species. Here we investigated the ability of sand-smelt (Atherina presbyter) larvae to discriminate between odours from different rocky reefs, and then tested the ability to discriminate between chemical signals of conspecifics from its own site and conspecifics from another site (kin recognition). Water and schools of sand-smelt larvae were collected in three different rocky reefs: Portinho da Arrábida (ARR), Avencas (AV), and Albufeira (ALB). Only larvae from ARR were subjected to olfactory choice tests; larvae from AV and ALB were used as conspecifics odour source. Our results suggest that even nearby reefs smell different and that fish larvae can tell the difference. Fish also exhibited a strong preference for conspecific cues from conspecifics of their natal reef when tested against odours of conspecifics of the “foreigner” reefs. Moreover, results suggest that both cues are equally relevant. This evidence comes from the fact that the combination of reef odour with conspecific odours is more attractive to sand smelt larvae than each cue in isolation, and when conspecific and reef cues are tested against each other, there is no clear preference for neither cues. Acknowledgements This work had the support of Fundação para a Ciência e Tecnologia through the strategic project UID/MAR/04292/2013, and a grant to Ana M. Faria (SFRH/BPD/68673/2010). Authors would like to thank António Roleira, Henrique Folhas and Pedro Duarte-Coelho for field and laboratory assistance. Keywords: Fish orientation, olfactory cues, habitat, Kin recognition, temperate fish larvae Conference: IMMR'18 | International Meeting on Marine Research 2018, Peniche, Portugal, 5 Jul - 6 Jul, 2018. Presentation Type: Poster Presentation Topic: Biodiversity, Conservation and Coastal Management Citation: Faria AM, Almada F, Silva G, Martins-Cardoso S and Gonçalves EJ (2019). Response to habitat-associated cues by sand smelt larvae. Front. Mar. Sci. Conference Abstract: IMMR'18 | International Meeting on Marine Research 2018. doi: 10.3389/conf.FMARS.2018.06.00008 Copyright: The abstracts in this collection have not been subject to any Frontiers peer review or checks, and are not endorsed by Frontiers. They are made available through the Frontiers publishing platform as a service to conference organizers and presenters. The copyright in the individual abstracts is owned by the author of each abstract or his/her employer unless otherwise stated. Each abstract, as well as the collection of abstracts, are published under a Creative Commons CC-BY 4.0 (attribution) licence (https://creativecommons.org/licenses/by/4.0/) and may thus be reproduced, translated, adapted and be the subject of derivative works provided the authors and Frontiers are attributed. For Frontiers’ terms and conditions please see https://www.frontiersin.org/legal/terms-and-conditions. Received: 30 May 2018; Published Online: 07 Jan 2019. * Correspondence: Dr. Ana M Faria, MARE-ISPA, Lisbon, Portugal, 1149-041, Portugal, afaria@ispa.pt Login Required This action requires you to be registered with Frontiers and logged in. To register or login click here. Abstract Info Abstract The Authors in Frontiers Ana M Faria Frederico Almada Goncalo Silva Sara Martins-Cardoso Emanuel J Gonçalves Google Ana M Faria Frederico Almada Goncalo Silva Sara Martins-Cardoso Emanuel J Gonçalves Google Scholar Ana M Faria Frederico Almada Goncalo Silva Sara Martins-Cardoso Emanuel J Gonçalves PubMed Ana M Faria Frederico Almada Goncalo Silva Sara Martins-Cardoso Emanuel J Gonçalves Related Article in Frontiers Google Scholar PubMed Abstract Close Back to top Javascript is disabled. Please enable Javascript in your browser settings in order to see all the content on this page.

Frontiers Events is a rapidly growing calendar management system dedicated to the scheduling of academic events. This includes announcements and invitations, participant listings and search functionality, abstract handling and publication, related events and post-event exchanges. Whether an organizer or participant, make your event a Frontiers Event!

Event Abstract Back to Event A computational approach for the discovery of lead-like compounds for anticancer drugs Sara M. Cruz1*, Susana Gaudêncio1, 2 and Florbela Pereira1 1 Faculty of Science and Technology - Universidade NOVA de Lisboa, LAQV-REQUIMTE - Department of Chemistry, Portugal 2 Faculty of Science and Technology - Universidade NOVA de Lisboa, UCIBIO-REQUIMTE - Department of Life Sciences, Portugal Between 2005 and 2010 nineteen drugs based on Natural Products (NPs) have been worldwide approved for various therapeutic purposes.1 However, the screening of a large number of compounds is expensive and time consuming, and considering that 95% of the world's diversity has yet to be explored,2 new ways of evaluating their bioactivity have to be implemented, e.g. computational modulations.The current work consists in two Quantitative Structure−Activity Relationship (QSAR) studies for the prediction of anticancer activity against human colon carcinoma HCT116 cell line, using the value of half maximal inhibitory concentration (IC50). In the first approach, the compounds were classified into either active or inactive cell-based anti-HCT116 assays. There were 5490 active compounds in the data set below the IC50 threshold of 10 μM (a cutoff for hit-to-lead activity studies). Only the compounds predicted to be active in the first classified model were submitted to the second model, a regression model that predicted the IC50 value of anticancer activity.In total 8822 compounds were extracted from the ChemBL, Zinc, Antimarine databases and recent literature indexed in Web of Science until October 2015. The best result for the prediction of the IC50 value of anticancer activity was obtained for the PubChem fingerprints, while for the classification the best model was achieved using molecular descriptors codifying 1D and 2D features. The models were built using three machine learning techniques: Random Forest (RF), Support Vector Machine (SVM) and k-Nearest Neighbor (kNN). The RF always outperform the other machine learning techniques. The performances of the models were successfully evaluated by cross validation, a test set validation, and an external test set validation. For the external test set of the classification model, there was not found any misclassified compounds with a probability of being active greater than or equal to 0.93. The best model for the second approach had a 0.614 root mean square error (RMSE) for the internal validation and 0.733 for the external validation. External validations through data from more recent literature and using marine NPs isolated in our research group are underway. Future work involves another QSAR study using 1D NMR data (1H and 13C) as descriptors, from crude extracts, fractions and pure compounds obtain from actinobacteria isolated from marine sediments collected from the Madeira Archipelago. Acknowledgements This research is the result of financial support from Fundação para a Ciência e a Tecnologia (FCT) and FEDER through grant PTDC/QUI-QUI/119116/2010, UID/QUI/50006/2013, UID/Multi/04378/2013, SFRH/BPD/108237/2015 and IF/00700/2014, and the European Union 7th Framework Programme (FP7/2007-2013) under grant agreement PCOFUND-GA-2009-246542 and 269138-NanoGuard. We thank ChemAxon Ltd. for access to JChem and Marvin, Molecular Networks GmbH for access to CORIN References Chen, J., Li, W., Yao, H. & Xu, J. Insights into drug discovery from natural products through structural modification. Fitoterapia 103, 231–241 (2015). David, B., Wolfender, J.-L. & Dias, D. A. The pharmaceutical industry and natural products: historical status and new trends. Phytochem. Rev. 14, 299–315 (2014). Keywords: QSAR modeling, HCT-116, IC50, anticancer drugs, chemoinformatics, Drug Discovery Conference: IMMR | International Meeting on Marine Research 2016, Peniche, Portugal, 14 Jul - 15 Jul, 2016. Presentation Type: Oral presentation Topic: Blue Biotechnology Citation: Cruz SM, Gaudêncio S and Pereira F (2016). A computational approach for the discovery of lead-like compounds for anticancer drugs. Front. Mar. Sci. Conference Abstract: IMMR | International Meeting on Marine Research 2016. doi: 10.3389/conf.FMARS.2016.04.00122 Copyright: The abstracts in this collection have not been subject to any Frontiers peer review or checks, and are not endorsed by Frontiers. They are made available through the Frontiers publishing platform as a service to conference organizers and presenters. The copyright in the individual abstracts is owned by the author of each abstract or his/her employer unless otherwise stated. Each abstract, as well as the collection of abstracts, are published under a Creative Commons CC-BY 4.0 (attribution) licence (https://creativecommons.org/licenses/by/4.0/) and may thus be reproduced, translated, adapted and be the subject of derivative works provided the authors and Frontiers are attributed. For Frontiers' terms and conditions please see https://www.frontiersin.org/legal/terms-and-conditions. Received: 14 Apr 2016; Published Online: 13 Jul 2016. * Correspondence: Miss. Sara M Cruz, Faculty of Science and Technology - Universidade NOVA de Lisboa, LAQV-REQUIMTE - Department of Chemistry, Caparica, 2829-516, Portugal, sm.cruz@campus.fct.unl.pt Login Required This action requires you to be registered with Frontiers and logged in. To register or login click here. Abstract Info Abstract The Authors in Frontiers Sara M Cruz Susana Gaudêncio Florbela Pereira Google Sara M Cruz Susana Gaudêncio Florbela Pereira Google Scholar Sara M Cruz Susana Gaudêncio Florbela Pereira PubMed Sara M Cruz Susana Gaudêncio Florbela Pereira Related Article in Frontiers Google Scholar PubMed Abstract Close Back to top Javascript is disabled. Please enable Javascript in your browser settings in order to see all the content on this page.

Event Abstract Back to Event Spatial and temporal seasonal trends in the major global upwelling areas during the last 30 years Rubén V. Rodríguez1*, Ramón G. Gesteira1, Francisco S. González2, Maite D. Rodríguez1 and Ines Á. Fernández1 1 Vigo university, Spain 2 Aveiro University, Portugal Winds at the ocean surface are a key element in the Earth system having a great impact on many economic activities and becoming really important to several oceanographic and atmospheric applications. Thus, wind above sea surface constitutes a critical parameter to analyze coastal phenomena as upwelling events. Upwelling regions are areas of high productivity compared to other areas of the ocean. In fact, over 20% of global fish catches occur in upwelling areas, although these areas occupy less than 1% of the surface of the world's oceans. Therefore, accurate surface wind datasets are needed to better analyze these processes. In this study wind data obtained from NCEP Climate Forecast System Reanalysis (CFSR) database was used to analyse the four most important upwelling systems (Benguela, Canarias, Peru and California). Wind data are available for the whole world at a spatial resolution of 0.3 x 0.3 degrees and a temporal resolution of 6h from January 1982 to December 2010. Alongshore wind stress was considered to analyse variations in upwelling intensity and trends were analysed on these upwelling regions. Comparison with previous studies showed the highly dependence of the results of the length of the time series, the selected areas, the season considered for the analysis and the resolution of the used database. Keywords: CFSR, wind stress, upwelling, East Pacific coast, East Atlantic coast, upwelling trends Conference: IMMR | International Meeting on Marine Research 2014, Peniche, Portugal, 10 Jul - 11 Jul, 2014. Presentation Type: Poster Presentation Topic: BIODIVERSITY, CONSERVATION AND COASTAL MANAGEMENT Citation: Rodríguez RV, Gesteira RG, González FS, Rodríguez MD and Fernández IÁ (2014). Spatial and temporal seasonal trends in the major global upwelling areas during the last 30 years. Front. Mar. Sci. Conference Abstract: IMMR | International Meeting on Marine Research 2014. doi: 10.3389/conf.fmars.2014.02.00099 Copyright: The abstracts in this collection have not been subject to any Frontiers peer review or checks, and are not endorsed by Frontiers. They are made available through the Frontiers publishing platform as a service to conference organizers and presenters. The copyright in the individual abstracts is owned by the author of each abstract or his/her employer unless otherwise stated. Each abstract, as well as the collection of abstracts, are published under a Creative Commons CC-BY 4.0 (attribution) licence (https://creativecommons.org/licenses/by/4.0/) and may thus be reproduced, translated, adapted and be the subject of derivative works provided the authors and Frontiers are attributed. For Frontiers’ terms and conditions please see https://www.frontiersin.org/legal/terms-and-conditions. Received: 25 Apr 2014; Published Online: 18 Jul 2014. * Correspondence: Mr. Rubén V Rodríguez, Vigo university, Ourense, Spain, ruvarela@uvigo.es Login Required This action requires you to be registered with Frontiers and logged in. To register or login click here. Abstract Info Abstract The Authors in Frontiers Rubén V Rodríguez Ramón G Gesteira Francisco S González Maite D Rodríguez Ines Á Fernández Google Rubén V Rodríguez Ramón G Gesteira Francisco S González Maite D Rodríguez Ines Á Fernández Google Scholar Rubén V Rodríguez Ramón G Gesteira Francisco S González Maite D Rodríguez Ines Á Fernández PubMed Rubén V Rodríguez Ramón G Gesteira Francisco S González Maite D Rodríguez Ines Á Fernández Related Article in Frontiers Google Scholar PubMed Abstract Close Back to top Javascript is disabled. Please enable Javascript in your browser settings in order to see all the content on this page.

Event Abstract Back to Event Detection and quantification of Hepatitis A and E vírus in wastewater from Tunisia Imen Ouardani1, Carmen F. Manso2, Manhjoub Aouni1 and Jesus L. Romalde2* 1 University of Monastir, Laboratory of Transmissible Diseases and Biological Active Substances LR99ES2,, Tunisia 2 Universidad de Santiago de Compostela, Spain Enteric viruses contaminating the environment represent a danger for public health. They are present quite frequently in wastewater and transmitted to humans by the fecal-oral route. The aim of our study was to detect hepatitis A and E viruses (HAV and HEV) in wastewater samples collected from 6 different Tunisian sewage treatment plants during thirteen months. A total of 325 samples were analyzed by real time reverse transcriptase-polymerase chain reaction (RT-qPCR). Results showed the presence of HAV contamination in 36% of the samples. Msaken (58.9%) and SidiBouzid (51.85%) regions showed the highest contamination, followed by Ouerdanine (35.2%), Kasserine (38.9%), Sbitla (23.6%) and El Jem (7.7%) regions. Contamination with HEV was significantly lower (4.9%), being detected HEV positive samples in SidiBouzid (9.25%), El Jem (5.76%), Kasserine (3.7%), Ouerdanine (3.7%), Sbitla (3.63%) and Msaken (3.6%) regions. On the another hand, our research found that, in entry points, 54% of wastewater samples were contaminated with HAV, whereas, in exit points a percentage of 17.9% was found. HAV values were also analyzed by plant showing percentages of positive samples in entry points between 15.38% and 85.18%, while in exit points values ranged from 3.57% to 57.14%. HAV was detected in exit points of all plants except El Jem region. Concerning HEV, the average percentage of contaminated wastewater at entry was 6.75% which was reduced until 3.1% at exit. By plant, HEV positive samples were detected only in three plants, Kasserine, El Jem and Sidi Bouzid at rates of 3.7% 3.84% and 11.11%, respectively. These results support previous findings on the stability of enteric viruses in wastewater and the inefficiency of the procedures employed in the sewage treatment plants. On the other hand, molecular procedures proved to be very sensitive to detect viral genomes in this type of samples. In conclusion, wastewater treatments employed in Tunisian plants can reduce the number of viral particles of hepatitis A and E but do not remove all of them, which constitute a potential risk for human health. Keywords: Hepatitis A virus, Hepatitis E virus, wastewater, RT-qPCR., quantification Conference: IMMR | International Meeting on Marine Research 2014, Peniche, Portugal, 10 Jul - 11 Jul, 2014. Presentation Type: Poster Presentation Topic: BIODIVERSITY, CONSERVATION AND COASTAL MANAGEMENT Citation: Ouardani I, Manso CF, Aouni M and Romalde JL (2014). Detection and quantification of Hepatitis A and E vírus in wastewater from Tunisia . Front. Mar. Sci. Conference Abstract: IMMR | International Meeting on Marine Research 2014. doi: 10.3389/conf.fmars.2014.02.00082 Copyright: The abstracts in this collection have not been subject to any Frontiers peer review or checks, and are not endorsed by Frontiers. They are made available through the Frontiers publishing platform as a service to conference organizers and presenters. The copyright in the individual abstracts is owned by the author of each abstract or his/her employer unless otherwise stated. Each abstract, as well as the collection of abstracts, are published under a Creative Commons CC-BY 4.0 (attribution) licence (https://creativecommons.org/licenses/by/4.0/) and may thus be reproduced, translated, adapted and be the subject of derivative works provided the authors and Frontiers are attributed. For Frontiers’ terms and conditions please see https://www.frontiersin.org/legal/terms-and-conditions. Received: 09 May 2014; Published Online: 18 Jul 2014. * Correspondence: Prof. Jesus L Romalde, Universidad de Santiago de Compostela, Santiago de Compostela, Spain, jesus.romalde@usc.es Login Required This action requires you to be registered with Frontiers and logged in. To register or login click here. Abstract Info Abstract The Authors in Frontiers Imen Ouardani Carmen F Manso Manhjoub Aouni Jesus L Romalde Google Imen Ouardani Carmen F Manso Manhjoub Aouni Jesus L Romalde Google Scholar Imen Ouardani Carmen F Manso Manhjoub Aouni Jesus L Romalde PubMed Imen Ouardani Carmen F Manso Manhjoub Aouni Jesus L Romalde Related Article in Frontiers Google Scholar PubMed Abstract Close Back to top Javascript is disabled. Please enable Javascript in your browser settings in order to see all the content on this page.

Frontiers Events is a rapidly growing calendar management system dedicated to the scheduling of academic events. This includes announcements and invitations, participant listings and search functionality, abstract handling and publication, related events and post-event exchanges. Whether an organizer or participant, make your event a Frontiers Event!

Event Abstract Back to Event Improved methodologies for extraction of salt in halophytes Tiago Morais1*, João Vaz1, Loïc Carvalho1 and Leonel Pereira1 1 IMAR (Institute of Marine Research), Department of Life Sciences, Portugal There are known culinary applications of halophytes species, such as Atriplex halimus, Portulaca oleracea, Beta maritima, Salicornia europaea and Arthrocnemum macrostachyum, mostly due to their mineral content, as they provide an alternative to common salt. Species of the last two genera possess a curious salt resistance mechanism, in which they can store Na+ in vacuoles in their shoots, using these vacuoles to stimulate growth. It is theorized that this mechanism enables the extraction of a vegetable salt, with a different Na+/Cl- ratio , providing healthier applications for human consumption, due to lower Na+ levels. In the present work we try to validate an efficient method for extracting a vegetable salt from a commercial mixture of Salicornia europaea and Salicornia bigelovii, as well as wild Arthrocnemum macrostachyum. We compared the efficiency of two extraction solvents used on this methodology. The used process presented mean yield rates around 70% (Salicornia) and 50% (Arthrocnemum). The comparison of the results between genera was the expected, since Salicornia species are more succulent than Arthrocnemum. This method yield rates in Salicornia appear to be higher than the expected based on previous publication. The data suggests other elements of interest may be differently distributed between the two genera. A nutritional profile, which we intend to do, may elucidate about the contents of vegetable salt. Acknowledgements The authors would like to acknowledge the valuable help of Dr. Jorge Paiva in the identification of plant species used in this experiment. References Khan, M. and Gul, B. (2002). Arthrocnemum macrostachyum: a potencial case for agriculture using above seawater salinity. Prospects for Saline Agriculture, 353-364. Parks, G., Dietrich, M. and Schumaker, K. (2002). Increased vacuolar Na+/H+ exchange activity in Salicornia bigelovii Torr. in responce to NaCl. Journal of Experimental Botany 371, 1055-1065 Tikhomirova, N. (2005). Influence of high concentrations of mineral salts on production process and NaCl accumulation by Salicornia europaea plants as a constituent of the LSS phototroph link. Advances in Space Research 35, 1589-1593. Balnokin, Y. et al. (2010). Use of halophytic plants to recycling NaCl in human liquid waste in a bioregenerative life support system. Advances in Space Research 46, 768-774. Kudo, N. et al. (2010). Sodium tolerance of plants in relation to ionic balance and the absorption ability of microelements. Soil Science and Plant Nutrition 56, 225–233. Ladeiro, B. (2012). Saline Agriculture in the 21st Century: Using Salt Contaminated Resources to Cope Food Requirements. Journal of Botany. doi: 10.1155/2012/310705. Ma, J. et al., (2013). Global Transcriptome Profiling of Salicornia europaea L. Shoots under NaCl Treatment. Plos One 8, 1-10. doi: 10.1371/journal.pone.0065877. Gul, B. et al. (2013). Germination Strategies of Halophyte Seeds under Salinity. Enviromental and Experimental Botany 92, 4-18. Ventura, Y. and Sagi M. (2013). Halophyte crop cultivation: The case for Salicornia e Sarcocornia. Enviromental and Experimental Botany 92, 144-153. Keywords: Halophytes, mineral content, Extraction method, salt alternative, Arthrocnemum macrostachyum, Salicornia spp. Conference: IMMR | International Meeting on Marine Research 2014, Peniche, Portugal, 10 Jul - 11 Jul, 2014. Presentation Type: Poster Presentation Topic: BLUE BIOTECH Citation: Morais T, Vaz J, Carvalho L and Pereira L (2014). Improved methodologies for extraction of salt in halophytes. Front. Mar. Sci. Conference Abstract: IMMR | International Meeting on Marine Research 2014. doi: 10.3389/conf.fmars.2014.02.00053 Copyright: The abstracts in this collection have not been subject to any Frontiers peer review or checks, and are not endorsed by Frontiers. They are made available through the Frontiers publishing platform as a service to conference organizers and presenters. The copyright in the individual abstracts is owned by the author of each abstract or his/her employer unless otherwise stated. Each abstract, as well as the collection of abstracts, are published under a Creative Commons CC-BY 4.0 (attribution) licence (https://creativecommons.org/licenses/by/4.0/) and may thus be reproduced, translated, adapted and be the subject of derivative works provided the authors and Frontiers are attributed. For Frontiers’ terms and conditions please see https://www.frontiersin.org/legal/terms-and-conditions. Received: 24 Apr 2014; Published Online: 18 Jul 2014. * Correspondence: Mr. Tiago Morais, IMAR (Institute of Marine Research), Department of Life Sciences, Coimbra, 3001-401, Portugal, tsmorais86@gmail.com Login Required This action requires you to be registered with Frontiers and logged in. To register or login click here. Abstract Info Abstract The Authors in Frontiers Tiago Morais João Vaz Loïc Carvalho Leonel Pereira Google Tiago Morais João Vaz Loïc Carvalho Leonel Pereira Google Scholar Tiago Morais João Vaz Loïc Carvalho Leonel Pereira PubMed Tiago Morais João Vaz Loïc Carvalho Leonel Pereira Related Article in Frontiers Google Scholar PubMed Abstract Close Back to top Javascript is disabled. Please enable Javascript in your browser settings in order to see all the content on this page.

Event Abstract Back to Event Isolation of marine microorganisms from the Peniche coast with high biotechnological potential Carina Coelho1, Joana A. Fernandes1, Patrícia Silva1, Clélia N. Afonso1 and Maria M. Sampaio1* 1 School of Tourism and Maritime Technology, GIRM - Marine Resources Research Group, Polytechnic Institute of Leiria , Portugal The marine environment represents more than two thirds of our planet and although it is a possible source of natural products with bioactivity, is still largely unexplored, which represents a huge window of opportunity. During the last decades Marine Biotechnology has focused some of their efforts in the search and study of marine bacteria and fungi. These microorganisms have been a valuable tool in several scientific studies, basically because they grow with relative ease, achieving considerable densities of cell mass. This is an important feature because these organisms also produce bioactive compounds, with applications in the pharmaceutical, cosmetic and food area, among others. Such compounds frequently arise from defense mechanisms or as response to stress. Annually, a growing number of new compounds from marine organisms are discovered, characterized and identified, and from these most are originated from bacteria and fungi. In the search process for natural products with proven activity, it is generally accepted that one should have a diverse and largely unexplored repertoire of microorganisms, as it enlarges the possibility of obtaining new and diverse metabolites. In the present work, results concerning the isolation of microorganisms of marine origin, obtained from the water and sediments of the Peniche coast, are shown. The main objective is to create a database of isolated microorganisms, and at the same time obtaining a basic characterization, with some interesting features from the biotechnology point of view, on viability of long-term of their cultures, as well as prepare raw extracts for bioactivity screening. Also basic microbiology characteristics will be register: gram stain, catalase, oxidase, use of different sugars and amino acids as a carbon source and on different concentrations growths of salinity, relatively to 20 strains already isolated. Acknowledgements *the first three authors contributed equally to this work and are ex-aequo first authors. Keywords: Antimicrobial activity, Biotechnology, marine bacteria, sediments., marine microbiology Conference: IMMR | International Meeting on Marine Research 2014, Peniche, Portugal, 10 Jul - 11 Jul, 2014. Presentation Type: Poster Presentation Topic: BLUE BIOTECH Citation: Coelho C, Fernandes JA, Silva P, Afonso CN and Sampaio MM (2014). Isolation of marine microorganisms from the Peniche coast with high biotechnological potential. Front. Mar. Sci. Conference Abstract: IMMR | International Meeting on Marine Research 2014. doi: 10.3389/conf.fmars.2014.02.00004 Copyright: The abstracts in this collection have not been subject to any Frontiers peer review or checks, and are not endorsed by Frontiers. They are made available through the Frontiers publishing platform as a service to conference organizers and presenters. The copyright in the individual abstracts is owned by the author of each abstract or his/her employer unless otherwise stated. Each abstract, as well as the collection of abstracts, are published under a Creative Commons CC-BY 4.0 (attribution) licence (https://creativecommons.org/licenses/by/4.0/) and may thus be reproduced, translated, adapted and be the subject of derivative works provided the authors and Frontiers are attributed. For Frontiers’ terms and conditions please see https://www.frontiersin.org/legal/terms-and-conditions. Received: 10 May 2014; Published Online: 18 Jul 2014. * Correspondence: Prof. Maria M Sampaio, School of Tourism and Maritime Technology, GIRM - Marine Resources Research Group, Polytechnic Institute of Leiria, Peniche, 2520-641, Portugal, msampaio@ipleiria.pt Login Required This action requires you to be registered with Frontiers and logged in. To register or login click here. Abstract Info Abstract The Authors in Frontiers Carina Coelho Joana A Fernandes Patrícia Silva Clélia N Afonso Maria M Sampaio Google Carina Coelho Joana A Fernandes Patrícia Silva Clélia N Afonso Maria M Sampaio Google Scholar Carina Coelho Joana A Fernandes Patrícia Silva Clélia N Afonso Maria M Sampaio PubMed Carina Coelho Joana A Fernandes Patrícia Silva Clélia N Afonso Maria M Sampaio Related Article in Frontiers Google Scholar PubMed Abstract Close Back to top Javascript is disabled. Please enable Javascript in your browser settings in order to see all the content on this page.