Editorial introductions

Coronary evaluation in patients with stroke: Recognizing the risk

A call from the European Academy of Neurology on COVID-19

Editorial from The New England Journal of Medicine — Progress of Dr. Friedmann's Demonstrations — The Execution of Charles the First — Mental Hygiene Exhibit and Conference — The Glasgow Lister Ward and Museum — The Prevention of Diseases of Occupation — American Academy of Arts and Sciences — Medical Notes

Harvey Williams Cushing (1869–1939) graduated from Yale College and Harvard Medical School, and worked at the Massachusetts General Hospital of Boston. He created the first anesthesia card, introduced the term “regional anesthesia” into medical practice, described the Cushing triad, and in 1901, the second in the world, performed a successful operation on the pituitary gland for acromegaly. In 1910, he accepted the offer to become the head of the department of surgery at Harvard Medical School and the chief surgeon at Peter Benton Brigham Hospital, located on the campus. In 1933, Cushing moved to Yale, where from 1933 to 1937. was a professor of neurology. In the US, Harvey Williams Cushing is honored as a pioneer of neurosurgery and the greatest neurosurgeon in world history. Cushing developed and improved the technique of many neurosurgical operations, proved the right to the very existence of intracranial surgery as a separate medical specialty. In 1939, he was honored to become an Honorary Member of the Royal Medical College in London. Harvey Williams Cushing died on October 7, 1939 from myocardial infarction. He was awarded honorary degrees in nine American and thirteen European universities; several state orders and medals; as well as many different awards and prizes. Harvey Williams Cushing was a member of the American Philosophical Society, the National Academy of Natural Sciences, and the American Academy of Humanities and Natural Sciences, a foreign member of the Royal Society of London, and also an honorary member of about seventy medical, surgical, and scientific communities in Europe, USA, South America and india.

Current Opinion in HIV and AIDS was launched in 2006. It is one of a successful series of review journals whose unique format is designed to provide a systematic and critical assessment of the literature as presented in the many primary journals. The fields of HIV and AIDS are divided into nine sections that are reviewed once a year. Each section is assigned one or two Section Editors, leading authorities in the area, who identify the most important topics at that time. Here we are pleased to introduce the Journal's Editors and the Section Editor for this issue. EDITORS Giuseppe PantaleoGiuseppe PantaleoProfessor Giuseppe Pantaleo was born June 17, 1956 in Bari, Italy. In 1980, he received his degree in medicine with full marks and honors, and in 1983 he became board certified in clinical hematology. His scientific career in the field of immunology began in 1983 working on the development of a limiting dilution cloning system which was critical for the subsequent studies aimed at the phenotypic and functional characterization of circulating T lymphocytes. From 1985 to 1987 he was amongst the pioneers in the delineation of the molecular and biochemical mechanisms involved in signal transduction in human T lymphocytes. In 1989, Professor Pantaleo joined the Laboratory of Immunoregulation, NIAID, NIH. He was the first to demonstrate the defective clonogenic potential of CD8+ T lymphocytes and the selective defect of HIV-specific cytotoxic T lymphocytes. He then studied the relationship between immune response and viral reservoirs in different anatomic compartments. He demonstrated that lymphoid organs function as a major reservoir for HIV, and that active virus replication occurs in lymphoid organs throughout the course of HIV disease including the prolonged period of clinical latency. These findings have completely changed the clinical and therapeutic management of HIV infection. In the following years, Professor Pantaleo has continued to provide important contributions to the understanding the immunopathogenesis of HIV infection. Amongst these it is noteworthy to mention the delineation of the virologic and immunologic events associated with primary HIV infection, and the observation that the proportion of CD8+ T cells involved in antiviral immune response was substantially higher compared to what was previously estimated. Since 1997 he has pioneered the field of immune-based intervention in HIV infection and he has been part of a European program for the development of a vaccine against HIV-AIDS. Since 2005, he has been leading the Poxvirus T-cell Vaccine Discovery Consortium, an international program to develop an HIV vaccine supported by the Bill and Melinda Gates Foundation. Furthermore, Professor Pantaleo has been leading several large projects supported by the European Commission. Professor Pantaleo is author and co-author of more than 300 publications in international scientific journals, he is on the editorial boards of several international journals and serves as ad hoc reviewers for several international journals. Professor Pantaleo is Professor of Medicine and Chief of the Division of Immunology and Allergy and of the Laboratory of AIDS Immunopathogenesis at the Centre Hospitalier Universitaire Vaudois, University of Lausanne, Switzerland. Since 2007, he has also been Executive Director of the Swiss Vaccine Research Institute. Steven G. DeeksSteven G. DeeksSteven G. Deeks, MD, is a Professor of Medicine in Residence at the University of California, San Francisco (UCSF), USA and a faculty member in the Division of HIV, Infectious Diseases and Global Medicine at Zuckerberg San Francisco General Hospital, USA. Dr Deeks has been engaged in HIV research and clinical care since 1993. He is a recognized expert on HIV-associated immune dysfunction and its impact on HIV persistence (the “reservoir”) and health during antiretroviral therapy. Dr Deeks has published over 400 peer-review articles, editorials and invited reviews on these and related topics. He has been the recipient of several NIH grants, and is one of the principal investigators of DARE (the Delaney AIDS Research Enterprise), which is an NIH-funded international collaboratory aimed at developing therapeutic interventions to cure HIV infection. He is also a member of the Board of Directors for the UCSF-based amfAR Institute for HIV Cure Research. He was elected to the American Society for Clinical Investigation (ASCI), is the Editor for Current Opinion in HIV and AIDS and serves on the advisory board for Science Translational Medicine. He is a former member of the Office of AIDS Research Advisory Council (ORAC) and of the Department on Health and Human Services Panel on Antiretroviral Guidelines for Adults and Adolescents. In addition to his clinical and translational investigation, Dr. Deeks maintains a primary care clinic for HIV infected adults. SECTION EDITOR Martin MarkowitzMartin MarkowitzDr Martin Markowitz is a graduate of Stanford Medical School, USA and completed his postgraduate training in Hematology/Oncology at Cornell Medical College, USA and Infectious Diseases at New York University, USA. Dr Markowitz has worked at the Aaron Diamond AIDS Research Center (ADARC) since 1992 and currently holds the positions of Clinical Director and Staff Investigator at ADARC and is an Aaron Diamond Professor at the Rockefeller University, USA. As of January 2, 2020, he will become the Anna and George Bobolas Professor of Research in Clinical Infectious Diseases in the Department of Medicine and Infectious Diseases at Columbia University Medical College, USA. His seminal work in elucidating the dynamics of HIV-1 infection in vivo along with his mentor Dr David Ho and colleagues at the Aaron Diamond AIDS Research Center formed the scientific foundation for triple combination therapy, a treatment paradigm that to this day remains the current standard of care. In addition, his research interests have included the pathogenesis and treatment of acute HIV-1 infection, the fitness and transmission of drug resistant HIV-1, and investigations of numerous novel antiretroviral agents as well as pathogenesis-based interventional trials. He was among the first to discuss HIV-1 cure, and perform trials of therapeutic vaccination and passive immunization as adjuncts to combination antiretroviral therapy. Dr Markowitz was among the first investigators to work with long acting antiretrviral agents for HIV prevention. Along with colleagues at the Aaron Diamond AIDS Research Center, he established the efficacy of Cabotegravir-Long Acting (CAB-LA) as pre-exposure prophylaxis (PrEP) in the rhesus macaque (RM)/SHIV162P3 non-human primate model of mucosal transmission in both the low dose rectal challenge model in males and the high dose intravaginal challenge model in females. His group also demonstrated activity of CAB-LA in preventing SIV infection in a stringent intravenous challenge model in RM. He served as Principal Investigator of “A Phase IIa Study to Evaluate the Safety, Tolerability and Acceptability of Long Acting Injections of the HIV Integrase Inhibitor, Cabotegravir, in HIV Uninfected Men (ÉCLAIR). More recently his group has performed preclinical studies with the first-in-class nucleoside reverse transcriptase translocation inhibitor, islatravir. They found that the drug protected RM against low dose rectal challenge with SHIV109CP3 at doses in low weekly doses given orally. They are currently exploring the activity of islatravir as PEP in the RM/SIV model. Dr Markowitz has co-authored nearly 200 peer-reviewed publications in medical journals including The New England Journal of Medicine, Lancet, Nature, Science, AIDS, JAIDS, and the Journal of Virology. He serves as a peer reviewer for a wide spectrum of journals and is a former chair of the AIDS Research Review Committee for the National Institutes of Health as well as private funding institutions. In addition to his work at the Aaron Diamond AIDS Research Center, Dr Markowitz served as a member of the HIV/AIDS Task Force of the UN Millennium Project and has been an active board member of community-based organizations.

British Journal of AddictionVolume 79, Issue 4 p. 241-243 Free Access Editorial M. A. H. Russell F.R.C.P., F.R.C. Psych., M. A. H. Russell F.R.C.P., F.R.C. Psych. Addiction Research Unit Institute of Psychiatry, 101, Denmark Hill. London S.E.5.Search for more papers by this author M. A. H. Russell F.R.C.P., F.R.C. Psych., M. A. H. Russell F.R.C.P., F.R.C. Psych. Addiction Research Unit Institute of Psychiatry, 101, Denmark Hill. London S.E.5.Search for more papers by this author First published: December 1984 https://doi.org/10.1111/j.1360-0443.1984.tb03864.xAboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onFacebookTwitterLinkedInRedditWechat References 1 Royal College of Physicians. (1983). Health or Smoking? Pitman: London . 2 Wald, N., Doll, R., and Copeland, G. K. E. (1981). Trends in tar nicotine and carbon monoxide yields of UK cigarettes manufactured since 1934. British Medical Journal, 282, 763– 765. 3 Russell, M. A. H., Jarvis, M. J., Lyler, R., and Feyerabend, C. (1980). Relation of nicotine yield of cigarettes to blood nicotine concentrations in smokers. British Medical Journal, 280, 972– 975. 4 Ebert, R. V., McNabb, M. E., McCusker, K. T., and Snow, S. L. (1983). Amount of nicotine and carbon monoxide inhaled by smokers of low-tar low-nicotine cigarettes. Journal of the American Medical Association, 250, 2840– 2842. 5 Benowitz, N. L., Hall, S. M., Herning, R. I., Jacob, P., Jones, R. T., and Osman, A. L. (1983). Smokers of low-yield cigarettes do not consume less nicotine. New England Journal of Medicine, 309, 139– 142. 6 U.S. Surgeon General (1981). The Changing cigarette. A report of the Surgeon General. DHEW. U.S. Government Printing Office. Washington D.C . 7 Kozlowski, L. T., Rickert, W. S., Robinson, J. C. and Grunberg, N. E. (1980). Have tar and nicotine yields of cigarettes changed. Science, 209, 1550– 1551. 8 Independent Scientific Committee on Smoking and Health. 3rd report. London : HMSO. 1983. 9 G. B. Gori, and F. G. Bock (eds). Banbury Report 3: A Safe Cigarette? Cold Spring Harbor Laboratory. Cold Spring Harbor. New York . 1980. 10 Tso, T. C. (1980). Ibid, pages 181– 190. 11 Doll, R. (1983). Prospects for prevention. British Medical Journal, 286, 445– 453. Volume79, Issue4December 1984Pages 241-243 ReferencesRelatedInformation

Current Opinion in Neurology was launched in 1988. It is one of a successful series of review journals whose unique format is designed to provide a systematic and critical assessment of the literature as presented in the many primary journals. The field of neurology is divided into 14 sections that are reviewed once a year. Each section is assigned a Section Editor, a leading authority in the area, who identifies the most important topics at that time. Here we are pleased to introduce the Journal's Section Editors for this issue. SECTION EDITORS Luis QuerolLuis QuerolLuis Querol (Valencia, 1980) graduated in Medicine at the University of Oviedo, Spain, and completed his residency in Neurology at the Santa Creu i Sant Pau Hospital in Barcelona. In 2009, he joined the group of Prof. Isabel Illa where he developed his doctoral thesis on the role of autoantibodies in immune-mediated neuropathies. In 2012, he worked as an associate researcher in the group of Dr Kevin O’Connor, Department of Neurology, Yale University (USA), where he developed projects related to autoantibodies in multiple sclerosis and myasthenia gravis. He completed his PhD in Medicine at the Universidad Autónoma de Barcelona, Spain, in 2013 thanks to studies that identified anti-contactin antibodies in a specific subgroup of patients with CIDP, in what is the first clinically useful marker detected in CIDP. Since then, he has led the auoimmune neurology clinics at Hospital Sant Pau in Barcelona and has continued a fruitful scientific production in the field of autoantibodies and biomarkers in autoimmune neurological disorders. Ichizo NishinoIchizo NishinoDr Ichizo Nishino, FAAN, FANA, is Director of Department of Neuromuscular Research, National Institute of Neuroscience, National Center of Neurology and Psychiatry (NCNP). He obtained his M.D. in 1989 and Ph.D. in 1998 from Kyoto University, Japan. After five years of training in clinical neurology and six years of research fellowship, including two years at Columbia University, he was appointed to his current position in 2001. By now, he has published more than 600 PubMed-listed papers in the field, including the reports of gene discoveries for MNGIE and Danon disease, and the report of a new muscle disease – megaconial congenital muscular dystrophy (OMIM: 602541) whose causative was also later identified by his own group. His laboratory functions as a nationwide referral center for muscle disease, providing diagnostic analyses for muscle pathology and genetic diagnosis. His lab receives around 80% of muscle biopsies performed in Japan (1103 cases in 2021) and he signs out all cases. As a result, more than 22,000 frozen muscle biopsy samples have been accumulated in his muscle repository, which is one of the largest collections of the patient's muscles. Currently, Dr Nishino is a Visiting Professor at six universities: University of Yamanashi (Japan), Shinshu University (Japan), Kaohsiung Medical University (Taiwan), Fu Jen Catholic University (Taiwan), Peking University First Hospital (China), and Siriraj Hospital Mahidol University (Thailand). He is also serving as President of Asian-Oceanian Myology Center and Executive Board member in several societies including World Muscle Society. Albert LudolphAlbert LudolphAlbert Ludolph is currently Professor of Neurology, Chair and Director of the Department of Neurology, University of Ulm, Ulm, Germany and Speaker of the Site Ulm of the German Center for Neurodegenerative diseses (DZNE, Helmholtz Society). He obtained his M.D. from the University of Mainz, Germany, in 1981 and is a boarded neurologist and psychiatrist (education from University of Münster, Germany). His research focusses on translational work in neurodegenerative diseases; his work is mirrored by more than 600 PubMed-listed papers. His specific focus of interests are motor neuron diseases, Huntington's disease and frontotemporal dementias. The Department of Neurology in Ulm is an international referral center in particular for patients with ALS/MND. In the past his research focused on neurotoxicological and neuropharmacological research in humans, but also non-human primates. He was involved and initiated studies of neurogenetics of ALS, of the epidemiology of the disease (established registers in Southern Germany, Egypt and Mongolia), of the definition of the neuroanatomical sequence of events describing ALS and FTD, the development of biomarkers in ALS and FTD and beyond, and several drug trials, including investigator-initiated interventions. In recent years he tried to define the preclinical period of ALS including the role of the hypothalamus and its metabolic consequences.

International audience

Endocrine disease and anaesthesia. A review of anaesthetic management in pituitary, adrenal and thyroid diseases.

The WFN comes of age

In December 2019, a novel coronavirus was identified in Wuhan City, Hubei Province, China and later the disease was named coronavirus disease 2019 (COVID-19). On March 11, 2020, the World Health Organization (WHO) officially announced that COVID-19 had reached global pandemic status. This article summarized the understanding of the etiology, pathogenesis, epidemiology, clinical characteristics, diagnosis, treatment, rehabilitation, and prevention and control measures of COVID-19 based on the available data and anti-epidemic experience in China.

UK Fifth National Colorectal Cancer Consensus Meeting 2010

Editorial introductions

British Journal of Neuroscience NursingVol. 13, No. 3 CommentManaging dysphagia in patients with neurological conditionsRosie ThompsonRosie ThompsonSearch for more papers by this authorRosie ThompsonPublished Online:14 Jul 2017https://doi.org/10.12968/bjnn.2017.13.3.106AboutSectionsView articleView Full TextPDF/EPUB ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareShare onFacebookTwitterLinked InEmail View article References Fletcher J (2015) Dealing with dysphagia, a multi-disciplinary approach. Nursing and Residential Care 17(8): 430-432. https://doi.org/10.12968/nrec.2015.17.8.430 Google ScholarHeadway (2010) Dysphagia after brain injury. https://tinyurl.com/y8qwu3df (accessed 21 June 2017) Google ScholarLancaster J (2015) Dysphagia: its nature, assessment and management. Br J Community Nurs Suppl Nutrition: S28-32. https://doi.org/http://dx.doi.org/10.12968/bjcn.2015.20.Sup6a.S28 Link, Google ScholarMarsh S, Ross N, Pittard A (2011) Neuromuscular disorders and anaesthesia. Part 1: generic anaesthetic management. Contin Educ Anaesth Crit Care Pain 11(4): 115-8. doi: https://doi.org/https://doi.org/10.1093/bjaceaccp/mkr020 Crossref, Google ScholarMalhi H (2016) Dysphagia: warning signs and management. Br J Nurs 25(10): 546–9. https://doi.org/http://dx.doi.org/10.12968/bjon.2016.25.10.546 Link, Google ScholarMiles A, McFarlane M, Kainth P, Parmar P (2014) Interdisciplinary management of dysphagia. Nursing and Residential Care. 16(10): 561-7. https://doi.org/https://doi.org/10.12968/nrec.2014.16.10.561 Link, Google ScholarMyatt R (2015) Nursing care of patients with a temporary tracheostomy. Nurs Stand 29(26): 42–9. https://doi.org/https://doi.org/10.7748/ns.29.26.42.e9742 Crossref, Google ScholarNational Institute for Health and Care Excellence (2006) Nutrition Support for Adults: Oral nutrition support, enteral tube feeding, and parenteral nutrition [CG32] https://tinyurl.com/kz8nu6h (accessed 21 June 2017) Google ScholarNational Patient Safety Agency (2011) Dysphagia Diet Food Texture Descriptors. https://tinyurl.com/l4o2say (accessed 21 June 2017) Google ScholarNational Tracheostomy Safety Project (2013) NTSP Manual. https://tinyurl.com/y7qy8jzg (accessed 21 June 2017) Google ScholarNutrition and Diet Resources (2014) Easier Swallowing: Fluid Thickening Guide. Nutrition and Diet Resources, Glasgow Google ScholarRoyal College of Physicians and British Society of Rehabilitation Medicine (2003) Rehabilitation following acquired brain injury: national clinical guidelines. RCP BSRM, London Google ScholarRoyal College of Physicians, British Society of Gastroenterology (2010) Oral Feeding Difficulties and Dilemmas: A Guide to Practical Care, Particularly Towards the End of Life. Royal College of Physicians, London Google ScholarRoyal College of Speech and Language Therapists (2013) RCSLT Resource Manual for Commissioning and Planning Services for SLCN: Dysphagia. RCSLT, London. http://tinyurl.com/ybdlszy3 (accessed 21 June 2017) Google ScholarRoyal College of Speech and Language Therapists (2014) Position paper. Speech and language therapy in adult critical care. http://tinyurl.com/y7lu853l (accessed 21 June 2017) Google ScholarScottish Intercollegiate Guidelines Network (2010) Management of Patients with Stroke: Identification and Management of Dysphagia. A National Clinical Guideline. https://tinyurl.com/y86mfoso (accessed 21 June 2017) Google ScholarSmithard DG (2015) Dysphagia: prevalence, management and the community nurse. Community Pract 88(10): 32–5 Google ScholarTanton M (2010) Developing a screening tool and training package to identify dysphagia in all settings. Nurs Times 106(15): 18–20 Google Scholar FiguresReferencesRelatedDetails 2 June 2017Volume 13Issue 3ISSN (print): 1747-0307ISSN (online): 2052-2800 Metrics History Published online 14 July 2017 Published in print 2 June 2017 Information© MA Healthcare LimitedPDF download

HomeCirculationVol. 33, No. 4s1Cardiac Valve Replacement Free AccessResearch ArticleAboutSections ToolsAdd to favoritesDownload citationsTrack citationsPermissions ShareShare onFacebookTwitterLinked InMendeleyReddit Jump toFree AccessResearch ArticleCardiac Valve Replacement Experience with the Durability of Silicone Rubber ALBERT STARR, WILL R. PIERIE, DONALD A. RAIBLE, M. LOWELL EDWARDS, GEORGE G. SIPOSS and WARREN D. HANCOCK ALBERT STARRALBERT STARR From the Department of Surgery, University of Oregon Medical School, Portland, Oregon, and Edwards Laboratories, Santa Ana, California. Search for more papers by this author , WILL R. PIERIEWILL R. PIERIE From the Department of Surgery, University of Oregon Medical School, Portland, Oregon, and Edwards Laboratories, Santa Ana, California. Search for more papers by this author , DONALD A. RAIBLEDONALD A. RAIBLE From the Department of Surgery, University of Oregon Medical School, Portland, Oregon, and Edwards Laboratories, Santa Ana, California. Search for more papers by this author , M. LOWELL EDWARDSM. LOWELL EDWARDS From the Department of Surgery, University of Oregon Medical School, Portland, Oregon, and Edwards Laboratories, Santa Ana, California. Search for more papers by this author , GEORGE G. SIPOSSGEORGE G. SIPOSS From the Department of Surgery, University of Oregon Medical School, Portland, Oregon, and Edwards Laboratories, Santa Ana, California. Search for more papers by this author and WARREN D. HANCOCKWARREN D. HANCOCK From the Department of Surgery, University of Oregon Medical School, Portland, Oregon, and Edwards Laboratories, Santa Ana, California. Search for more papers by this author Originally published1 Apr 1966https://doi.org/10.1161/01.CIR.33.4S1.I-115Circulation. 1966;33:I-115–I-123"Cardiac Valve Replacement ." 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Moacanin J, Lawson D, Chin H, Harrison E and Blankenhorn D (2009) Prediction of Lipid Uptake by Prosthetic Heart Valve Poppets from Solubility Parameters, Biomaterials, Medical Devices, and Artificial Organs, 10.3109/10731197309118872, 1:1, (183-190), Online publication date: 1-Jan-1973. Hawker R, Bernstein L, Nicks R, Grant A and Leckie B (1971) BALL VARIANCE COMPLICATING PROSTHETIC REPLACEMENT OF THE AORTIC VALVE, Medical Journal of Australia, 10.5694/j.1326-5377.1971.tb87518.x, 1:4, (205-208), Online publication date: 1-Jan-1971. Donovan T, Low H, Bucknam C and Stoughton P (2016) Poppet Wear in Cardiac Valvular Prostheses, Vascular Surgery, 10.1177/153857447100500109, 5:1, (48-59), Online publication date: 1-Jan-1971. Yacoub M, Lise M, Patterson M and Ross D (1969) Hemolytic Phenomena Following Insertion of the Cloth-Covered Starr-Edwards Valve Prosthesis, The Annals of Thoracic Surgery, 10.1016/S0003-4975(10)66224-8, 8:2, (161-165), Online publication date: 1-Aug-1969. 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Sauvage L, Viggers R, Robel S, Wood S, Berger K and Wesolowski S (1968) PROSTHETIC HEART VALVE REPLACEMENT, Annals of the New York Academy of Sciences, 10.1111/j.1749-6632.1968.tb20289.x, 146:1 Materials in, (289-313), Online publication date: 1-Jan-1968. Low H and Lefemine A (1967) Acute Mitral Insufficiency Due to Jamming of a Disc-Valve Prosthesis, The Annals of Thoracic Surgery, 10.1016/S0003-4975(10)66480-6, 4:1, (71-73), Online publication date: 1-Jul-1967. Laforet E (1967) Death Due to Swelling of Ball Component of Aortic Ball-Valve Prosthesis, New England Journal of Medicine, 10.1056/NEJM196705042761808, 276:18, (1025-1027), Online publication date: 4-May-1967. Cabot R, Castleman B, McNeely B, McNeely W and Putschar W (1967) Case 16-1967, New England Journal of Medicine, 10.1056/NEJM196704132761510, 276:15, (857-866), Online publication date: 13-Apr-1967. Flege J, Vlad P and Ehrenhaft J (1967) Congenital mitral incompetence, The Journal of Thoracic and Cardiovascular Surgery, 10.1016/S0022-5223(19)43249-2, 53:1, (138-144), Online publication date: 1-Jan-1967. April 1, 1966Vol 33, Issue 4s1 Advertisement Article InformationMetrics © 1966 American Heart Association, Inc.https://doi.org/10.1161/01.CIR.33.4S1.I-115 Originally publishedApril 1, 1966 Advertisement