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  • https://doi.org/10.1145/2330784.2330965Copy DOI Icon

Gene regulatory network reverse engineering using population based incremental learning and K-means

  • Jul 7, 2012
  • Leon Palafox +1 more
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Abstract

Finding interactions among genes is one of the main problems in molecular biology. In this paper, we use a novel approach to model the gene's regulations, or Gene Regulatory Networks (GRNs). We use a Recursive Neural Network (RNN) to model the networks, and then use Population Based Incremental Learning (PBIL) enhanced with K-means to find the optimum parameters of the Neural Network. We present experiments with real data, we compare our algorithm with others approaches by calculating different statistics for the solutions.

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