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  • https://doi.org/10.1109/icbme68496.2025.11392420Copy DOI Icon

Generative Adversarial Networks: A Feasibility Study

  • Nov 19, 2025
  • S Hooman Hosseini-Zahraei +1 more
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Abstract

Automated classification of human gait, a critical indicator of neuromuscular health, is often hindered by the dependence of supervised machine learning on extensive labeled pathological datasets, which are scarce and difficult to obtain. This paper explores the feasibility of a paradigm towards unsupervised learning, proposing a framework based on a Wasserstein Generative Adversarial Network with Gradient Penalty (WGAN-GP). The WGAN-GP is trained exclusively on healthy gait patterns from a single young subject's shankmounted inertial measurement unit (IMU) to build a model of healthy movement. The framework utilizes a reconstruction-based anomaly detection strategy, where abnormalities are quantified by the magnitude of the error when attempting to reconstruct a new gait cycle from the learned healthy model. Evaluated using real-world data from healthy subjects (both young and old) and for individuals with Parkinson's disease, the model showed strong performance, achieving an area under the curve (AUC) of 0.96. Notably, the framework also demonstrated sensitivity to non-pathological, age-related variations in gait. This feasibility study demonstrates the ability of the proposed WGAN-GP-based unsupervised detection method as a data-efficient and generalizable alternative. Consequently, it paves the way for future validation on larger clinical datasets to characterize mobility impairments in various disorders and age groups.

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