Image Processing Techniques for Improving Quality of 3D Profile in Digital Holographic Microscopy Using Deep Learning Algorithm.

Optical character recognition (OCR) is an important branch in the field of machine vision. It involves pattern recognition, image processing, digital signal processing, artificial intelligence and other disciplines. It is a comprehensive. It has important use value and theoretical significance in high-tech fields such as word information processing, office automation, machine translation and real-time monitoring system. In the 21st century, with the popularity of smart phones with high-definition cameras, OCR has a new pursuit in its development: more and more people pick up their mobile phones to photograph the things and scenes they see and obtain the text information in the pictures. Therefore, the recognition of characters in natural scenes has become a brand-new topic. In the past, text detection and text recognition algorithms were basically based on artificially designed features and traditional image processing methods. These features and algorithms were difficult to design and needed a lot of professional knowledge and experience support, so the accuracy was not high and they were not generalized. In recent years, with the rapid development of deep learning technology, breakthroughs have been made in the fields of computer vision such as image classification, object detection and semantic segmentation. Deep learning algorithm is a data-driven algorithm. The algorithm based on deep learning can automatically discover and learn the hidden feature rules in a large number of data through iterative training, without too much human intervention, so it has better generalization than traditional image processing related algorithms.

Deep learning has gained immense popularity in scientific computing, and its algorithms are widely used in complex problem-solving industries. Every deep learning algorithm use different types of neural networks to perform indented tasks. Deep learning (DL) algorithms have emerged from different machine learning and soft computing methodologies. Since then, a number of deep learning (DL) algorithms have been recently introduced in the scientific community and applied in various application fields. Today, the use of DLs has become indispensable due to their intelligence, effective learning, accuracy and reliability in model creation. However, a comprehensive list of DL algorithms has not yet been presented in the scientific literature. This article lists the most popular DL algorithms and their application areas. Deep learning uses ANN artificial neural networks to perform convoluted calculations on huge amounts of data. It is a type of machine learning based on the structure and function of the human brain. Deep learning algorithms train machines by learning from examples. Industries such as healthcare, e-commerce, entertainment and advertising often use deep learning.

The purpose of this study was to develop and evaluate the performance of a convolutional neural network (CNN) that uses a novel A-line based classification approach to detect cancer in OCT images of breast specimens. Deep learning algorithms have been developed for OCT ophthalmology applications using pixel-based classification approaches. In this study, a novel deep learning approach was developed that classifies OCT A-lines of breast tissue. De-identified human breast tissues from mastectomy and breast reduction specimens were excised from patients at Columbia University Medical Center. A total of 82 specimens from 49 patients were imaged with OCT, including both normal tissues and non-neoplastic tissues. The proposed algorithm utilized a hybrid 2D/1D convolutional neural network (CNN) to map each single B-scan to a 1D label vector, which were derived from manual annotation. Each A-line was labelled as one of the following tissue types: ductal carcinoma in situ (DCIS), invasive ductal carcinoma (IDC), adipose, and stroma. Five-fold cross-validation Dice scores across tissue types were: 0.82-0.95 for IDC, 0.54-0.75 for DCIS, 0.67-0.91 for adipose, and 0.61-0.86 for stroma. In a second experiment, IDC and DCIS were combined as a single tissue class (malignancy) while stroma and adipose were combined as a second tissue class (non-malignancy). In this setup, the experiment yielded five-fold cross-validation Dice scores between 0.89-0.93, respectively. Future work includes acquiring more patient samples and to compare the algorithm to previous works, including both deep learning and traditional automatic image processing methods for classification of breast tissue in OCT images.

Skin cancer detection by deep learning and sound analysis algorithms: A prospective clinical study of an elementary dermoscope

Background Machine learning (ML) algorithm support vector machine (SVM) performed better than Thrombolysis in Myocardial Infarction (TIMI) score for ASIAN STEMI patients. However, Deep Learning (DL) effectiveness in the multiethnic ASIAN population has yet to be determined. DL has automatic learning of the feature from a given dataset without the need to conduct feature selection. However, the selected features by the algorithm is black box. Identifying features associated with mortality is essential to recognize characteristics of patients with high risk for better patient management. Purpose To develop a DL algorithm for in-hospital mortality in multiethnic STEMI patients using predictors identified from the SVM algorithm. To investigate DL performance constructed using predictors from SVM feature extraction and expert-recommended predictors. Methods We constructed four algorithms; a) DL and SVM algorithms with predictors identified from the SVM variable importance b) DL and SVM using predictors based on expert recommendation. We used registry data from the National Cardiovascular Disease Database of 11397 patient's. Fifty parameters including demographics, cardiovascular risk, medications and clinical variables were considered. The Area under the curve (AUC) is the performance evaluation metric. Algorithms were validated against the TIMI and tested using the same validation data. SVM variable importance with backward elimination was used to select and rank important variables. Results DL algorithms outperform SVM and TIMI on the validation dataset; i) DL with SVM selected predictors (15 predictors, AUC = 0.97), ii) DL with expert-recommended predictors (16 predictors, AUC = 0.96), iii) SVM with selected predictors (15 predictors, AUC = 0.92), iv) SVM with expert-recommended predictors (AUC = 0.89) and TIMI (AUC = 0.82). Common predictors across SVM feature selection, expert-recommendation and TIMI are: age, heart rate, Killip class, fasting blood glucose, systolic blood pressure, comorbid diseases and ST-elevation. SVM feature selection also identified diuretics, PCI and pharmacotherapy drugs as predictors that improve mortality prediction in STEMI patients. Our findings suggest that the TIMI score underestimates patients risk of mortality. DL algorithm using selected predictors classified 35% of nonsurvival patients as high risk (risk probabilities >50%) compared to only 12.7% nonsurvival patients by TIMI (score >5) (Figure below). Conclusions In the ASIAN population, patients with STEMI can be better classified using the DL algorithm compared to the ML and TIMI score. Combining ML feature selection with DL allows the identification of distinct factors in a unique ASIAN population for better mortality prediction than relying solely on an expert recommendation as it is a very subjective approach. Continuous validation on population-specific algorithms using DL and ML is needed before implementing in a real clinical setting. Funding Acknowledgement Type of funding sources: Public grant(s) – National budget only. Main funding source(s): Technology Development Fund 1 TIMI performance on validation setDL performance on validation set

Improving the performance of machine learning algorithms to overcome the curse of dimensionality while maintaining interpretability is still a challenging issue for researchers in artificial intelligence. Patch learning (PL), based on the improved adaptive network-based fuzzy inference system (ANFIS) and continuous local optimization for the input domain, is characterized by high accuracy. However, PL can only handle low-dimensional data set regression. Based on the parallel and serial ensembles, two deep patch learning algorithms with embedded adaptive fuzzy systems (DPLFSs) are proposed in this paper. First, using the maximum information coefficient (MIC) and Pearson's correlation coefficients for feature selection, the variables with the least relationship (linear or nonlinear) are excluded. Second, principal component analysis is used to reduce the complexity further of DPLFSs. Meanwhile, fuzzy C-means clustering is used to enhance the interpretability of DPLFSs. Then, an improved PL method is put forward for the training of each sub-fuzzy system in a fashion of bottom-up layer-by-layer, and finally, the structure optimization is performed to significantly improve the interpretability of DPLFSs. Experiments on several benchmark data sets show the advantages of a DPLFS: (1) it can handle medium-scale data sets; (2) it can overcome the curse of dimensionality faced by PL; (3) its precision and generalization are greatly improved; and (4) it can overcome the poor interpretability of deep learning networks. Compared with shallow and deep learning algorithms, DPLFSs have the advantages of interpretability, self-learning, and high precision. DPLFS1 is superior for medium-scale data; DPLFS2 is more efficient and effective for high-dimensional problems, has a faster convergence, and is more interpretable.

Feature mining for encrypted malicious traffic detection with deep learning and other machine learning algorithms

The resource limitation of mobile commerce systems cause the problem that the existing image processing software based on the centralized computing mode had difficulty in running in mobile commerce systems. This paper gives a solution for the problem by adopting web service-based image processing approach. The solution reduces the resource consumption of mobile commerce systems by distributing image processing tasks to service providers, service registry centers and service requesters. Furthermore, a web service discovery algorithm called WBSD is presented. Service providers adopt the WBSD to provide efficient services and increase image processing speed. Compared with traditional methods of image processing, Web service-based image processing method has the advantages of loose coupling and component oriented and can take full advantage of the computing resources in heterogeneous network. Thus web service-based image processing approach can effectively solve the resource bottle-neck that traditional image processing software had.

BackgroundMachine learning (ML) algorithm support vector machine (SVM) performed better than Thrombolysis in Myocardial Infarction (TIMI) score for ASIAN STEMI patients. However, Deep Learning (DL) effectiveness in the multiethnic ASIAN population has yet to be determined. DL has automatic learning of the feature from a given dataset without the need to conduct feature selection. However, the selected features by the algorithm is black box. Identifying features associated with mortality is essential to recognize characteristics of patients with high risk for better patient management.PurposeTo develop a DL algorithm for in-hospital mortality in multiethnic STEMI patients using predictors identified from the SVM algorithm. To investigate DL performance constructed using predictors from SVM feature extraction and expert-recommended predictors.MethodsWe constructed four algorithms; a) DL and SVM algorithms with predictors identified from the SVM variable importance b) DL and SVM using predictors based on expert recommendation. We used registry data from the National Cardiovascular Disease Database of 11397 patient's. Fifty parameters including demographics, cardiovascular risk, medications and clinical variables were considered. The Area under the curve (AUC) is the performance evaluation metric. Algorithms were validated against the TIMI and tested using the same validation data. SVM variable importance with backward elimination was used to select and rank important variables.ResultsDL algorithms outperform SVM and TIMI on the validation dataset; i) DL with SVM selected predictors (15 predictors, AUC = 0.97), ii) DL with expert-recommended predictors (16 predictors, AUC = 0.96), iii) SVM with selected predictors (15 predictors, AUC = 0.92), iv) SVM with expert-recommended predictors (AUC = 0.89) and TIMI (AUC = 0.82). Common predictors across SVM feature selection, expert-recommendation and TIMI are: age, heart rate, Killip class, fasting blood glucose, systolic blood pressure, comorbid diseases and ST-elevation. SVM feature selection also identified diuretics, PCI and pharmacotherapy drugs as predictors that improve mortality prediction in STEMI patients. Our findings suggest that the TIMI score underestimates patients risk of mortality. DL algorithm using selected predictors classified 35% of nonsurvival patients as high risk (risk probabilities >50%) compared to only 12.7% nonsurvival patients by TIMI (score >5) (Figure below).ConclusionsIn the ASIAN population, patients with STEMI can be better classified using the DL algorithm compared to the ML and TIMI score. Combining ML feature selection with DL allows the identification of distinct factors in a unique ASIAN population for better mortality prediction than relying solely on an expert recommendation as it is a very subjective approach. Continuous validation on population-specific algorithms using DL and ML is needed before implementing in a real clinical setting.Funding AcknowledgementType of funding sources: Public grant(s) – National budget only. Main funding source(s): Technology Development Fund 1TIMI performance on validation setDL performance on validation set

In last few decades, digital images are growing with a rapid pace on and off the Internet, and given the volume of the images, the need of better storage, processing, and retrieval of images has raised. One of the retrieval techniques that is focus of this work is content-based image retrieval (CBIR) in which similar images are searched from a pool of images without manually annotating them; rather, in CBIR, other features of images that discriminate them from other images are used. By finding the better discriminative features of a collection of images, an efficient and generalized CBIR system can be built. The success and the efficiency of such a system depend on the choice of the features of images used to identify them. Generally, the images are stored at a very low level in pixels, but to get better results or in other words better features, we need to store these images at a very high level in order to reduce the semantic gap. There has been very extensive research on CBIR using the traditional methods of image processing. With the advancement of deep learning systems, deep learning can be used for large range of problems. In this work, we investigated the use of deep learning, more precisely auto-encoders, for the feature extraction and representation of images in CBIR, and we reached to the retrieval efficiency of ≈ 80%.KeywordsCBIRDeep learningConvolutional neural networksSemantic gapAuto-encoders

Recent technological advancements allow deep learning to be employed in practically every aspect of life. Because deep learning techniques are so precise, they can be used in medicine to classify and detect various diseases. The coronavirus (SARSCoV2) epidemic has recently affected global health systems. One of the ways to diagnose SARSCoV2 is with a chest X-ray. This paper proposes a deep learning technique to distinguish SARSCoV2 positive and normal cases. In this study, we fine-tuned the deep learning models and hyperparameters, and the fine-tuned deep learning models performed significantly better. To classify X-ray images, we developed a system based on deep learning algorithms that includes five models: Xception, VGG19, ResNet50, DenseNet121, and Inception. We offer deep learning models and algorithms that have been trained and evaluated to support medical efforts and reduce medical staff workload when dealing with SARSCoV2. In addition, the classification model that was proposed yields positive results because it makes use of accurate classification of the SARSCoV2 disease based on medical images. Additionally, the performance of our proposed CNN classification method for medical imaging was evaluated using various edge-based neural networks. The accuracy of tertiary classification with CNN will decrease as the number of classes in the training network grows. In tertiary classification, which includes normal and SARSCoV2 positive images, the proposed model achieved a 0.9897 accuracy. The proposed algorithm achieves a high level of classification accuracy when using the DenseNet121 model for binary classification.

Deep Learning (DL) algorithms have become the de facto Machine Learning (ML) algorithm for large scale data analysis. DL algorithms are computationally expensive -- even distributed DL implementations which use MPI require days of training (model learning) time on commonly studied datasets. Long running DL applications become susceptible to faults -- requiring development of a fault tolerant system infrastructure, in addition to fault tolerant DL algorithms. This raises an important question: What is needed from MPI for designing fault tolerant DL implementations? In this paper, we address this problem for permanent faults. We motivate the need for a fault tolerant MPI specification by an in-depth consideration of recent innovations in DL algorithms and their properties, which drive the need for specific fault tolerance features. We present an in-depth discussion on the suitability of different parallelism types (model, data and hybrid); a need (or lack thereof) for check-pointing of any critical data structures; and most importantly, consideration for several fault tolerance proposals (user-level fault mitigation (ULFM), Reinit) in MPI and their applicability to fault tolerant DL implementations. We leverage a distributed memory implementation of Caffe, currently available under the Machine Learning Toolkit for Extreme Scale (MaTEx). We implement our approaches by extending MaTEx-Caffe for using ULFM-based implementation. Our evaluation using the ImageNet dataset and AlexNet, and GoogLeNet neural network topologies demonstrates the effectiveness of the proposed fault tolerant DL implementation using OpenMPI based ULFM.

Wind energy has the possibility for bringing out energy in a very constant and sustainable manner being a notable and eligible source. Although, wind energy does include numerous challenges like, the halted asset of wind plants, early investment costs, and therefore, the strain in discovering areas of wind efficiency. The major objective for proposing this work is to determine the power efficiency of wind turbines, which will also aid in the formulation of a proposal to reduce wind turbine maintenance costs. During this research, data analysis of turbine generators is performed on day to day wind speed info using machine learning and deep learning algorithms. A way is put forward by us to support deep learning and machine learning algorithms which can predict different values of power reliably. Hence, the execution of machine and deep learning algorithms are analyzed. For forecasting for a longer term these algorithms may be used for wind generation rate with historical relation to wind speed info. Index Terms: Wind turbine,machine learning algorithm

The aim of this study is to develop a predictive model utilizing deep learning and machine learning techniques that will inform clinical decision-making by predicting the 1-year postoperative recovery of patients with lumbar disk herniation. The clinical data of 470 inpatients who underwent tubular microdiscectomy (TMD) between January 2018 and January 2021 were retrospectively analyzed as variables. The dataset was randomly divided into a training set (n = 329) and a test set (n = 141) using a 10-fold cross-validation technique. Various deep learning and machine learning algorithms including Random Forests, Extreme Gradient Boosting, Support Vector Machines, Extra Trees, K-Nearest Neighbors, Logistic Regression, Light Gradient Boosting Machine, and MLP (Artificial Neural Networks) were employed to develop predictive models for the recovery of patients with lumbar disk herniation 1 year after surgery. The cure rate score of lumbar JOA score 1 year after TMD was used as an outcome indicator. The primary evaluation metric was the area under the receiver operating characteristic curve (AUC), with additional measures including decision curve analysis (DCA), accuracy, sensitivity, specificity, and others. The heat map of the correlation matrix revealed low inter-feature correlation. The predictive model employing both machine learning and deep learning algorithms was constructed using 15 variables after feature engineering. Among the eight algorithms utilized, the MLP algorithm demonstrated the best performance. Our study findings demonstrate that the MLP algorithm provides superior predictive performance for the recovery of patients with lumbar disk herniation 1 year after surgery.

BACKGROUNDTraditional methods of developing predictive models in inflammatory bowel diseases (IBD) rely on using statistical regression approaches to deriving clinical scores such as the Crohn's disease (CD) activity index. However, traditional approaches are unable to take advantage of more complex data structures such as repeated measurements. Deep learning methods have the potential ability to automatically find and learn complex, hidden relationships between predictive markers and outcomes, but their application to clinical prediction in CD and IBD has not been explored previously.AIMTo determine and compare the utility of deep learning with conventional algorithms in predicting response to anti-tumor necrosis factor (anti-TNF) therapy in CD.METHODSThis was a retrospective single-center cohort study of all CD patients who commenced anti-TNF therapy (either adalimumab or infliximab) from January 1, 2010 to December 31, 2015. Remission was defined as a C-reactive protein (CRP) < 5 mg/L at 12 mo after anti-TNF commencement. Three supervised learning algorithms were compared: (1) A conventional statistical learning algorithm using multivariable logistic regression on baseline data only; (2) A deep learning algorithm using a feed-forward artificial neural network on baseline data only; and (3) A deep learning algorithm using a recurrent neural network on repeated data. Predictive performance was assessed using area under the receiver operator characteristic curve (AUC) after 10× repeated 5-fold cross-validation.RESULTSA total of 146 patients were included (median age 36 years, 48% male). Concomitant therapy at anti-TNF commencement included thiopurines (68%), methotrexate (18%), corticosteroids (44%) and aminosalicylates (33%). After 12 mo, 64% had CRP < 5 mg/L. The conventional learning algorithm selected the following baseline variables for the predictive model: Complex disease behavior, albumin, monocytes, lymphocytes, mean corpuscular hemoglobin concentration and gamma-glutamyl transferase, and had a cross-validated AUC of 0.659, 95% confidence interval (CI): 0.562-0.756. A feed-forward artificial neural network using only baseline data demonstrated an AUC of 0.710 (95%CI: 0.622-0.799; P = 0.25 vs conventional). A recurrent neural network using repeated biomarker measurements demonstrated significantly higher AUC compared to the conventional algorithm (0.754, 95%CI: 0.674-0.834; P = 0.036).CONCLUSIONDeep learning methods are feasible and have the potential for stronger predictive performance compared to conventional model building methods when applied to predicting remission after anti-TNF therapy in CD.