Intelligent personalized content recommendations based on neural networks

Information wikis and especially Wikipedia are attracting an increasing attention for informal learning. The nature of wikis enables learners to freely navigate the learning environment and independently construct knowledge without being forced to follow a predefined learning path in accordance with the constructivist learning theory. To the best of our knowledge, no effective personalized content recommendation approach has yet been defined to support informal learning from wikis. Therefore, we propose a personalized content recommendation framework that extrapolates topical navigation graphs from learners' free navigation and integrates them with fuzzy thesauri for automatic and adaptive personalized content recommendations to support informal learning in wikis. We design user studies and conceptual knowledge rubric to evaluate the impact of personalized recommendations on learning from Wikipedia. Results show that the proposed personalized content recommendation framework generates highly relevant recommendations. Evaluation of informal learning reveals that users who use Wikipedia with personalized recommendations can achieve higher scores on conceptual knowledge assessment compared to those who use Wikipedia without recommendations. Learners who use Wikipedia with personalized recommendations are able to utilize larger number of concepts and are able to make comparisons and state relations between concepts.

This article presents an algorithm for recommending content in educational disciplines used at ITMO University. The primary objective of the algorithm is to enhance the process of designing syllabi, thereby increasing their efficiency and effectiveness. The authors of the research have developed an algorithm based on an analysis of user interactions with the Educational Program Maker and the available educational materials. The recommendation algorithm is built upon a thorough analysis of prerequisite requirements and learning outcomes for each discipline. By incorporating user interaction data with the Educational Program Maker and the discipline-specific content, the algorithm can identify the most suitable educational materials to support the learning process. This, in turn, assists educational program developers in creating well-structured and coherent syllabi. The research findings demonstrate the effectiveness of the content recommendation algorithm, which contributes to the improvement of educational program design at ITMO University. The authors emphasize the importance of utilizing user interaction data and accessible content to provide accurate and personalized content recommendations throughout the educational process. This article holds significant practical value for educational program developers and professionals involved in the field of education, enabling them to optimize the design and maintenance of academic disciplines based on the content recommendation algorithm.

Postherpetic neuralgia (PHN), a complication of herpes zoster, significantly impacts the quality of life of affected patients. Research indicates that early intervention for pain can reduce the occurrence or severity of PHN. This study aims to develop a predictive model and scoring table to identify patients at risk of developing PHN following acute herpetic neuralgia, facilitating informed clinical decision-making. We conducted a retrospective review of 524 hospitalized patients with herpes zoster at The First Affiliated Hospital of Zhejiang Chinese Medical University from December 2020 to December 2023 and classified them according to whether they had PHN, collecting a comprehensive set of 30 patient characteristics and disease-related indicators, 5 comorbidity indicators, 2 disease score values, and 10 serological indicators. Relevant features associated with PHN were identified using the least absolute shrinkage and selection operator (LASSO). Then, the patients were divided into a training set and a test set in a 4:1 ratio, with comparability tested using univariate analysis. Six models were established in the training set using machine learning methods: support vector machines, logistic regression, random forest, k-nearest neighbor, gradient boosting, and neural network. The performance of these models was evaluated in the test set, and a nomogram based on logistic regression was used to create a PHN prediction score table. Eight non-zero characteristic variables selected from the LASSO regression results were included in the model, including age [area under the curve (AUC)=0.812, p<0.001], Numerical Rating Scale (NRS) (AUC=0.792, p<0.001), receiving treatment time (AUC=0.612, p<0.001), rash recovery time (AUC=0.680, p<0.001), history of malignant tumor (AUC=0.539, p<0.001), history of diabetes (AUC=0.638, p<0.001), varicella-zoster virus immunoglobulin M (AUC=0.620, p<0.001), and serum nerve-specific enolase (AUC=0.659, p<0,001). The gradient boosting model outperformed other classifier models on the test set with an AUC of 0.931, 95% confidence interval (CI) (0.882-0.980), accuracy of 0.886 (95% CI 0.809-0.940). In the test set, our predictive scoring table achieved an AUC of 0.820 (95% CI 0.869-0.970) with accuracy of 0.790 (95% CI 0.700-0.864). This study presents a methodology for predicting the development of postherpetic neuralgia in shingles patients by analyzing historical case data, employing various machine learning techniques, and selecting the optimal model through comparative analysis. In addition, a logistic regression model has been used to create a scoring table for predicting the postherpetic neuralgia.

The aim of the study was to inspect the acoustic properties and sleep characteristics of a preapneic snoring sound. The feasibility of forecasting upcoming respiratory events by snoring sound was also investigated. Participants with habitual snoring or a heavy breathing sound during sleep were recruited consecutively. Polysomnography was conducted, and snoring-related breathing sound was recorded simultaneously. Acoustic features and sleep features were extracted from 30-second samples, and a machine learning algorithm was used to establish 2 prediction models. A total of 74 eligible participants were included. Model 1, tested by 5-fold cross-validation, achieved an accuracy of 0.92 and an area under the curve of 0.94 for respiratory event prediction. Model 2, with acoustic features and sleep information tested by Leave-One-Out cross-validation, had an accuracy of 0.78 and an area under the curve of 0.80. Sleep position was found to be the most important among all sleep features contributing to the performance of the 2 models. Preapneic sound presented unique acoustic characteristics, and snoring-related breathing sound could be deployed as a real-time apneic event predictor. The models, combined with sleep information, serve as a promising tool for an early warning system to forecast apneic events. Wang B, Yi X, Gao J, etal. Real-time prediction of upcoming respiratory events via machine learning using snoring sound signal. J Clin Sleep Med. 2021;17(9):1777-1784.

This study aims to develop and validate a machine learning-based mortality risk prediction model for V-A ECMO patients to improve the precision of clinical decision-making. This multicenter retrospective cohort study included 280 patients receiving V-A ECMO from the Second Affiliated Hospital of Guangxi Medical University, Yulin First People’s Hospital, and the MIMIC-IV database. The data from the Second Affiliated Hospital of Guangxi Medical University and the MIMIC-IV database were merged and randomly divided in a 7:3 ratio into a training set and an internal validation set, respectively. The dataset from Yulin First People’s Hospital was reserved as an external validation cohort. The primary study outcome was defined as in-hospital mortality.Feature selection was conducted using Lasso regression, followed by the development of six machine learning models: Logistic Regression, Random Forest (RF), Deep Neural Network (DNN), Support Vector Machine (SVM), LightGBM, and CatBoost. Model performance was assessed using the Area Under the Curve (AUC), accuracy, sensitivity, specificity, and F1 score. Model validation was performed through calibration and decision curve analysis. Feature importance was evaluated using SHAP, and subgroup analysis was conducted to assess the model’s applicability across different clinical scenarios. In internal validation, the Logistic Regression model performed the best, with an AUC of 0.86 (95% CI: 0.77–0.93), accuracy of 0.76, sensitivity of 0.73, specificity of 0.79, and an F1 score of 0.73. It outperformed other models (RF: AUC = 0.79, DNN: AUC = 0.78, SVM: AUC = 0.76, LightGBM: AUC = 0.71, CatBoost: AUC = 0.77). External validation yielded consistent results, with the Logistic Regression model’s AUC at 0.75 (95% CI: 0.56–0.92), accuracy of 0.69, sensitivity of 0.64, specificity of 0.73, and an F1 score of 0.66. Calibration curve analysis revealed that the Logistic Regression model had the lowest Brier score (0.1496), indicating the most reliable predicted probabilities. Decision curve analysis demonstrated that the model provided the highest net benefit across most decision thresholds. SHAP analysis identified lactate, age, and albumin as key predictors of mortality, with lactate and age positively correlated, and albumin negatively correlated. Subgroup analysis revealed better performance in the cardiac arrest group (AUC = 0.81), non-sepsis group (AUC = 0.75), and non-diabetes group (AUC = 0.78). The Logistic Regression-based mortality risk prediction model for V-A ECMO patients demonstrated comparable or even favorable performance to more complex machine learning models, with the advantage of higher interpretability.By explicitly incorporating lactate, age, and albumin as the principal predictors, this model facilitates precise risk stratification and provides practical support for clinical decision-making in ECMO management.Supplementary InformationThe online version contains supplementary material available at 10.1038/s41598-025-25423-4.

Machine learning-based receiver operating characteristic (ROC) curves for crisp and fuzzy classification of DNA microarrays in cancer research

Freezing of gait (FOG) is one of the most debilitating motor symptoms experienced by patients with Parkinson's disease (PD). FOG detection is possible using acceleration data from wearable sensors, and a convolutional neural network (CNN) is often used to determine the presence of FOG epochs. We compared the performance of a standard CNN for the detection of FOG with two more complex networks, which are well suited for time series data, the MiniRocket and the InceptionTime. We combined acceleration data of people with PD across four studies. The final data set was split into a training (80%) and hold-out test (20%) set. A fifth study was included as an unseen test set. The data were windowed (2 s) and five-fold cross-validation was applied. The CNN, MiniRocket, and InceptionTime models were evaluated using a receiver operating characteristic (ROC) curve and its area under the curve (AUC). Multiple sensor configurations were evaluated for the best model. The geometric mean was subsequently calculated to select the optimal threshold. The selected model and threshold were evaluated on the hold-out and unseen test set. A total of 70 participants (23.7 h, 9% FOG) were included in this study for training and testing, and in addition, 10 participants provided an unseen test set (2.4 h, 11% FOG). The CNN performed best (AUC = 0.86) in comparison to the InceptionTime (AUC = 0.82) and MiniRocket (AUC = 0.76) models. For the CNN, we found a similar performance for a seven-sensor configuration (lumbar, upper and lower legs and feet; AUC = 0.86), six-sensor configuration (upper and lower legs and feet; AUC = 0.87), and two-sensor configuration (lower legs; AUC = 0.86). The optimal threshold of 0.45 resulted in a sensitivity of 77% and a specificity of 58% for the hold-out set (AUC = 0.72), and a sensitivity of 85% and a specificity of 68% for the unseen test set (AUC = 0.90). We confirmed that deep learning can be used to detect FOG in a large, heterogeneous dataset. The CNN model outperformed more complex networks. This model could be employed in future personalized interventions, with the ultimate goal of using automated FOG detection to trigger real-time cues to alleviate FOG in daily life.

Prostate Cancer Risk Prediction and Online Calculation Based on Machine Learning Algorithm

Context-awareness involved in e-learning includes awareness to knowledge context, awareness to social context, and awareness to technical context. This study proposes the use of context-awareness for personalized learning content recommendation in e-learning environments, and discusses the key steps in the recommendation mechanism.

In the era of information abundance, the demand for personalized content recommendations has become paramount. Recommendation engines, particularly those employing collaborative filtering, play a pivotal role in delivering tailored suggestions based on user preferences. As technology evolves, the need to enhance the effectiveness of prediction algorithms within these engines becomes increasingly crucial. This research endeavors to contribute to this evolving landscape by delving into collaborative filtering methodologies, identifying challenges, and proposing novel strategies to elevate the accuracy and relevance of predictions in recommendation systems. Through this exploration, we aim to not only refine existing models but also pave the way for more sophisticated and reliable personalized content recommendations.&#x0D; This research aims to enhance prediction accuracy in recommendation engines utilizing collaborative filtering. Through an in-depth exploration of collaborative filtering techniques, we propose innovative approaches to improve the effectiveness of predictions. Our study addresses key challenges in collaborative filtering models, offering insights into refined algorithms and methodologies. By fine-tuning the collaborative filtering process, we anticipate a substantial boost in the overall performance of recommendation engines, ultimately advancing the field of personalized content suggestion. The simulation is performed using Java language and using two datasets Movie Lens 1M and Movie Lens 100K.The proposed model was evaluated using the Mean Absolute Error, Precision, and Recall.&#x0D; The proposed model achieved a mean absolute error value ranging between 0.78 and 0.84 using the Movie Lens 100K dataset, and a mean absolute error value ranging between 0.72 and 0.74 using the Movie Lens 1M dataset for different values of the number of user groups. As for precision and recall, the precision of the proposed model ranged between 0.97 and 0.985 using the Movie Lens 100K data set, and a precision value ranging between 0.944 and 0.954 using the Movie Lens 1M data set, also for different values of the number of user groups.&#x0D; As for the recall results, the proposed model achieved a recall value ranging between 0.755 and 0.85 using the Movie Lens 100K dataset, and a recall value ranging between 0.72 and 0.75 using the Movie Lens 100K dataset, also for different values of the number of user groups. These results were compared with the PMF, HPF, and NMF algorithms, where the proposed model proved its clear superiority over these algorithms. Using this analysis of the matrix allows us to obtain a good prediction accuracy of users' preferences and to find common groups of people with similar preferences.

Implicit feedback (e.g., clicks) is widely used in content recommendations. However, clicks only reflect user preferences according to their first impressions. They do not capture the extent to which users continue to engage with the content. Our analysis shows that more than half of the clicks on music and short videos are followed by skips from two real-world datasets. In this paper, we leverage post-click feedback, e.g. skips and completions, to improve the training and evaluation of content recommenders. Specifically, we experiment with existing collaborative filtering algorithms and find that they perform poorly against post-click-aware ranking metrics. Based on these insights, we develop a generic probabilistic framework to fuse click and post-click signals. We show how our framework can be applied to improve pointwise and pairwise recommendation models. Our approach is shown to outperform existing methods by 18.3% and 2.5% respectively in terms of Area Under the Curve (AUC) on the short-video and music dataset. We discuss the effectiveness of our approach across content domains and trade-offs in weighting various user feedback signals.

Combinations of Scheimpflug tomography, ocular coherence tomography and air-puff tonometry improve the detection of keratoconus

To determine whether radiomics features derived from diffusion-weighted imaging (DWI) and arterial spin labeling (ASL) can improve the differentiation between radiation-induced brain injury (RIBI) and tumor recurrence (TR) in glioma patients. A total of 4199 radiomics features were extracted from conventional MRI, apparent diffusion coefficient (ADC), and cerebral blood flow (CBF) maps, obtained from 96 pathologically confirmed WHO grade 2~4 gliomas with enhancement after standard treatment. The intraclass correlation coefficient (ICC) was used to test segmentation stability between two doctors. Radiomics features were selected using the Mann-Whitney U test, LASSO regression, and RFE algorithms. Four machine learning classifiers were adopted to establish radiomics models. The diagnostic performance of multiparameter, conventional, and single-parameter MRI radiomics models was compared using the area under the curve (AUC). The models were evaluated in the subsequent independent validation set (n = 30). Eight important radiomics features (3 from conventional MRI, 1 from ADC, and 4 from CBF) were selected. Support vector machine (SVM) was chosen as the optimal classifier. The diagnostic performance of the multiparameter MRI radiomics model (AUC 0.96) was higher than that of the conventional MRI (AUC 0.88), ADC (AUC 0.91), and CBF (AUC 0.95) radiomics models. For subgroup analysis, the multiparameter MRI radiomics model showed similar performance, with AUCs of 0.98 in WHO grade 2~3 and 0.96 in WHO grade 4. The incorporation of noninvasive DWI and ASL into the MRI radiomics model improved the diagnostic performance in differentiating RIBI from TR; ASL, especially, played a significant role. • The multiparameter MRI radiomics model was superior to the conventional MRI radiomics model in differentiating glioma recurrence from radiation-induced brain injury. • Diffusion and perfusion MRI could improve the ability of the radiomics model in predicting the progression in patients with glioma. • Arterial spin labeling played an important role in predicting glioma progression using radiomics models.

Industry 4.0 brought with it by the next-gen Industry 5.0 and Society 5.0 paradigms, catalysed by Artificial Intelligence (AI), Machine Learning (ML), and Deep Learning (DL) technologies. These advances have the benefit of encouraging sustainability, improving output, and updating manufacturing. By enabling self-decision, continuous monitoring, and predictive maintenance with the processing of large data, AI is dramatically reducing downtime and associated costs of system downtime. As a result, ML algorithms, in light of their applicability for continuous learning and adaptation, have contributed to enriching product quality, streamlining supply networks and okaying personalized customer experiences. Neural networks are also being leveraged to improve computer vision and speech capabilities, for applications such as smart automation and human-robot cooperation in challenging industrial contexts. Industry 5.0 truly puts humans back at the centre of innovation. It is aimed to create an evolved society in which AI, ML, and DL are fused with the digital and physical world Society 5.0. The integration aims to address a plethora of societal challenges: environmental sustainability, health and ageing population, among others. It is a convergence of these said technologies that lead to a paradigm shift towards more resilient, adaptive, and sustainable industrial ecosystems. This paper aims to address these questions in a systematic way to offer a comprehensive view of what the future industrial landscape could look like leveraging the promise of Industry 4.0 and Industry 5.0 thus, and more opportunities to embrace intelligent and sustainable industries of tomorrow.

ABSTRACTIntroduction:This study aimed to evaluate the usefulness of machine learning (ML) and neural network (NN) models versus traditional statistical methods for estimating biochemical recurrence (BCR) in men following robot-assisted radical prostatectomy (RARP).Methods:Patients who underwent RARP from November 2011 to July 2022 were taken in the study. Patients with BCR were assigned to Group 2, whereas those without BCR were placed in Group 1. Preoperative and postoperative parameters, together with demographic data, were recorded in the database. This study used one NN, the radial basis function NN (RBFNN), and two ML approaches, the K-nearest neighbor and XGboost ML models, to predict BCR.Results:Following the application of exclusion criteria, 516 patients were deemed eligible for the study. Of those, 234 (45.3%) developed BCR, and 282 (54.7%) did not. The results showed that the median follow-up period was 24 (15–42) months, and the median BCR diagnosis was 12.23 ± 15.58 months. The area under the curve (AUC) for the Cox proportional hazard analysis was 0.77. The receiver-operating characteristic curves (AUCs) for the XGBoost and K closest neighbor models were 0.82 and 0.69, respectively. The RBFNN’s AUC was 0.82.Conclusions:The classical statistical model was outperformed by XGBoost and RBFNN models in predicting BCR.