Medical Concept Extraction using Smartphone and Natural Language Processing Techniques (poster)

1 IntroductionOrganizations focus on automate their processes in order to improve efficiency, reduce costs, and/or reduce human beings' errors in an easy and rapid manner. Business process management (BPM) methods provide a solution to this issue. In this context, information systems like CRM, ERP, SCM, etc. have known an increasing demand. The main problem consists of the length of the business process specifications. If new regulations appear, these specifications must be adapted. Manually extraction of visual models is time consuming. During time, a series of solutions were proposed. The literature shows a crowd of approaches that extracts data models [1], [2], [3], and process models [4], [5] from Natural Language (NL) text. This paper aims to analyze the Natural Language Processing (NLP) techniques and tools used in order to provide different types of visual representations.On the last few years, approaches based on NLP have been developed in order to automate process conversion from NL text. NLP plays an important role in NL text analysis as NLP tries to understand speech and text as humans beings would do. Colloquialism, abbreviations or typos make this task a challenging one. NLP has the origins in 1950s when Alan Turing proposed the Turing test [6], by introducing the imitation game. Since then, the literature shows a plethora of NLP tools [7], [8], [9], [10] using several machine learning techniques, our focus being on those applied on data models and process models discovery from NL text, starting with the first language parser [11] to the actual ones like NLTk [7], [8], ANTLR1, etc.Linguistic analysis is closely tied to NLP. Liddy [12] highlights 7 levels of linguistic analysis: a) Phonetic or Phonological level: how words are pronounced, b) Morphological level: prefixes, suffixes and roots analysis, c) Lexical level: word level analysis including lexical meaning and Part-Of-Speech (POS) analysis, d) Syntactic level: grammatical analysis of words in a sentence, e) Semantic level: determining the possible meanings of sentences, f) Discourse level: interpreting structure and meaning for texts larger than a sentence, g) Pragmatic level: understanding the purpose of a language.Some of the problems approached by NLP are: POS tagging, parsing, Named Entity Recognition (NER), chunking, Semantic Role Labeling (SRL). Anaphora resolution [13] refers to the interpretation of the link between the anaphor and its antecedents.The remainder of the paper is organized as follows: Section 2 briefly outlines the NLP domain, describing the levels of linguistic analysis and the main NLP approaches of analyzing NL requirements. Section 3 focuses on data and process models extraction from NL text. This section makes an introduction to Object Oriented Analysis and Business Process Modeling and analyses the existing tools that discover data and process models from text. Subsequently, Section 4 summarizes the results of this work and the conclusions are drawn in Section 5.2NLPA detailed review on NLP is given in [14] and in [15]. Jones [14] divides the history of NLP into four phases: the first starts at the beginning of the 1940s and lasts to the late 1960s, the second begins from the end of 60s and lasts to the end of 70s, the third is represented by late 80s, where the fourth phase starts in the late of 90s. Next, we will detail each phase as they were defined in [14] and [15]. First phase treated machine translation issues, while the second focused on artificial intelligence. The third phase can be called grammatico-logical phase, which is followed by the lexical phase. A fifth phase is proposed in [16] where formal theories and statistical data are combined. Since this study was published first in 1994 and then it was re-organized in 2001 we can add the sixth phase: from 2000 until present where NLP techniques are combined in order to contribute to visual models extraction.Software requirements are usually written in NL which is asymmetric and irregular [17]. …

The inspection of documents written in natural language with computers has become feasible thanks to the advances in Natural Language Processing (NLP) techniques. However, certain applications require a deeper semantic analysis of the text to produce good results. In this article, we present an exploratory study of semantic-aware NLP techniques for discovering latent concerns in use case specifications. For this purpose, we propose two NLP techniques, namely: semantic clustering and semantically-enriched rules. After evaluating these two techniques and comparing them with a technique developed by other researchers, results have showed that semantic NLP techniques hold great potential for detecting candidate concerns. Particularly, if these techniques are properly configured, they can help to reduce the efforts of requirement analysts and promote better quality in software development.

Extracting the relations between medical concepts is very valuable in the medical domain. Scientists need to extract relevant information and semantic relations between medical concepts, including protein and protein, gene and protein, drug and drug, and drug and disease. These relations can be extracted from biomedical literature available on various databases. This study examines the extraction of semantic relations that can occur between diseases and drugs. Findings will help specialists make good decisions when administering a medication to a patient and will allow them to continuously be up to date in their field. The objective of this work is to identify different features related to drugs and diseases from medical texts by applying Natural Language Processing (NLP) techniques and UMLS ontology. The Support Vector Machine classifier uses these features to extract valuable semantic relationships among text entities. The contributing factor of this research is the combination of the strength of a suggested NLP technique, which takes advantage of UMLS ontology and enables the extraction of correct and adequate features (frequency features, lexical features, morphological features, syntactic features, and semantic features), and Support Vector Machines with polynomial kernel function. These features are manipulated to pinpoint the relations between drug and disease. The proposed approach was evaluated using a standard corpus extracted from MEDLINE. The finding considerably improves the performance and outperforms similar works, especially the f-score for the most important relation “cure,” which is equal to 98.19%. The accuracy percentage is better than those in all the existing works for all the relations.

<italic xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">Context:</i> User stories have been widely accepted as artifacts to capture the user requirements in agile software development. They are short pieces of texts in a semi-structured format that express requirements. Natural language processing (NLP) techniques offer a potential advantage in user story applications. <italic xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">Objective:</i> Conduct a systematic literature review to capture the current state-of-the-art of NLP research on user stories. <italic xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">Method:</i> The search strategy is used to obtain relevant papers from SCOPUS, ScienceDirect, IEEE Xplore, ACM Digital Library, SpringerLink, and Google Scholar. Inclusion and exclusion criteria are applied to filter the search results. We also use the forward and backward snowballing techniques to obtain more comprehensive results. <italic xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">Results:</i> The search results identified 718 papers published between January 2009 to December 2020. After applying the inclusion/exclusion criteria and the snowballing technique, we identified 38 primary studies that discuss NLP techniques in user stories. Most studies used NLP techniques to extract aspects of who, what, and why from user stories. The purpose of NLP studies in user stories is broad, ranging from discovering defects, generating software artifacts, identifying the key abstraction of user stories, and tracing links between model and user stories. <italic xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">Conclusion:</i> NLP can help system analysts manage user stories. Implementing NLP in user stories has many opportunities and challenges. Considering the exploration of NLP techniques and rigorous evaluation methods is required to obtain quality research. As with NLP research in general, the ability to understand a sentence’s context continues to be a challenge.

Aspirin-exacerbated respiratory disease (AERD) is an acquired inflammatory condition characterized by the presence of asthma, chronic rhinosinusitis with nasal polyposis, and respiratory hypersensitivity reactions on ingestion of aspirin or other nonsteroidal anti-inflammatory drugs (NSAIDs). Despite AERD having a classic constellation of symptoms, the diagnosis is often overlooked, with an average of greater than 10 years between the onset of symptoms and diagnosis of AERD. Without a diagnosis, individuals will lack opportunities to receive effective treatments, such as aspirin desensitization or biologic medications. Our aim was to develop a combined algorithm that integrates both natural language processing (NLP) and machine learning (ML) techniques to identify patients with AERD from an electronic health record (EHR). A rule-based decision tree algorithm incorporating NLP-based features was developed using clinical documents from the EHR at Mayo Clinic. From clinical notes, using NLP techniques, 7 features were extracted that included the following: AERD, asthma, NSAID allergy, nasal polyps, chronic sinusitis, elevated urine leukotriene E4 level, and documented no-NSAID allergy. MedTagger was used to extract these 7 features from the unstructured clinical text given a set of keywords and patterns based on the chart review of 2 allergy and immunology experts for AERD. The status of each extracted feature was quantified by assigning the frequency of its occurrence in clinical documents per subject. We optimized the decision tree classifier's hyperparameters cutoff threshold on the training set to determine the representative feature combination to discriminate AERD. We then evaluated the resulting model on the test set. The AERD algorithm, which combines NLP and ML techniques, achieved an area under the receiver operating characteristic curve score, sensitivity, and specificity of 0.86 (95% CI 0.78-0.94), 80.00 (95% CI 70.82-87.33), and 88.00 (95% CI 79.98-93.64) for the test set, respectively. We developed a promising AERD algorithm that needs further refinement to improve AERD diagnosis. Continued development of NLP and ML technologies has the potential to reduce diagnostic delays for AERD and improve the health of our patients.

Machine learning techniques have long been the foundations of speech processing. Bayesian classiflcation, decision trees, unsupervised clustering, the EM algorithm, maximum entropy, etc. are all part of existing speech recognition systems. The success of statistical speech recognition has led to the rise of statistical and empirical methods in natural language processing. Indeed, many of the machine learning techniques used in language processing, from statistical part-of-speech tagging to the noisy channel model for machine translation have roots in work conducted in the speech fleld. However, advances in learning theory and algorithmic machine learning approaches in recent years have led to signiflcant changes in the direction and emphasis of the statistical and learning centered research in natural language processing and made a mark on natural language and speech processing. Approaches such as memory based learning, a range of linear classiflers such as Boosting, SVMs and SNoW and others have been successfully applied to a broad range of natural language problems, and these now inspire new research in speech retrieval and recognition. We have seen an increasingly close collaboration between voice and language processing researchers in some of the shared tasks such as spontaneous speech recognition and understanding, voice data information extraction, and machine translation. The purpose of this special issue was to invite speech and language researchers to communicate with each other, and with the machine learning community on the latest machine learning advances in their work. The call for papers was met with great enthusiasm from the speech and natural language community. Thirty six submissions were received; each paper was reviewed by at least three reviewers. Only ten papers were selected re∞ecting not only some of the best work on machine learning in the areas of natural language and spoken language processing but also what we view as a collection of papers that represent current trends in these areas of research both from the perspective of

The AI voice assistant mobile application was developed to aid drivers in operating their mobile phones while driving without touching their phones. The literature review examines multiple innovative artificial technologies involved in applications with voice assistants in natural language processing (NLP) techniques. The methodology used involved a qualitative approach, and the design science paradigm was used for the development of the voice assistant for smartphones with NLP techniques. NLP techniques that were applied in the development of the AI voice assistant are smart synthesis, data flow sequence, core and interface accessing, part of speech tagging, named entity recognition, conference resolution, and porter stemming. Some of the operations that are achieved by the application include arithmetic calculations based on voice commands and returning the computer result via voice, searching the internet based on user voice input, and providing a response via voice assistance.

In the past few years there has been a growing interest in the employment of verbal productions as digital biomarkers, namely objective, quantifiable behavioural data that can be collected and measured by means of digital devices, allowing for a low-cost pathology detection, classification and monitoring. Numerous research papers have been published on the automatic detection of subtle verbal alteration, starting from written texts, raw speech recordings and transcripts, and such linguistic analysis has been singled out as a cost-effective method for diagnosing dementia and other medical conditions common among elderly patients (e.g., cognitive dysfunctions associated with metabolic disorders, dysarthria). To provide a critical appraisal and synthesis of evidence concerning the application of natural language processing (NLP) techniques for clinical purposes in the geriatric population. In particular, we discuss the state of the art on studying language in healthy and pathological ageing, focusing on the latest research efforts to build non-intrusive language-based tools for the early identification of cognitive frailty due to dementia. We also discuss some challenges and open problems raised by this approach. We performed a scoping review to examine emerging evidence about this novel domain. Potentially relevant studies published up to November 2021 were identified from the databases of MEDLINE, Cochrane and Web of Science. We also browsed the proceedings of leading international conferences (e.g., ACL, COLING, Interspeech, LREC) from 2017 to 2021, and checked the reference lists of relevant studies and reviews. The paper provides an introductory, but complete, overview of the application of NLP techniques for studying language disruption due to dementia. We also suggest that this technique can be fruitfully applied to other medical conditions (e.g., cognitive dysfunctions associated with dysarthria, cerebrovascular disease and mood disorders). Despite several critical points need to be addressed by the scientific community, a growing body of empirical evidence shows that NLP techniques can represent a promising tool for studying language changes in pathological aging, with a high potential to lead a significant shift in clinical practice. What is already known on this subject Speech and languages abilities change due to non-pathological neurocognitive ageing and neurodegenerative processes. These subtle verbal modifications can be measured through NLP techniques and used as biomarkers for screening/diagnostic purposes in the geriatric population (i.e., digital linguistic biomarkers-DLBs). What this paper adds to existing knowledge The review shows that DLBs can represent a promising clinical tool, with a high potential to spark a major shift to dementia assessment in the elderly. Some challenges and open problems are also discussed. What are the potential or actual clinical implications of this work? This methodological review represents a starting point for clinicians approaching the DLB research field for studying language in healthy and pathological ageing. It summarizes the state of the art and future research directions of this novel approach.

Medical data is increasing rapidly. The rapid fusion of medical record text data, medical laboratory data and image data in many regional hospitals have brought light to the screening, diagnosis and treatment of diseases. Medical text data records the patient's detailed condition and treatment process, with abundant information. As a branch of artificial intelligence, deep learning is gradually penetrating the medical field. The application of deep learning in the medical field shows great application prospects. Therefore, mining the knowledge contained in medical texts can provide better medical services for the majority of patients, which has good theoretical and practical significance. In this paper, the content of medical texts was analyzed, and the test questions and standard answers of the USMLE Step 2 Clinical Skills Exam were used as data sets to explore the core content of the medical chief texts. After comparing and analyzing different methods, such as BERT and DeBERTa, an intelligent follow-up system based on DeBERTa was finally proposed, hoping to help clinicians read medical data more effectively and weaken the problem of poor diagnosis results caused by personal academic ability differences.

For any applications related to Natural Language Processing (NLP), reasoning has been recognized as a necessary underlying aspect. Many of the existing work in NLP deals with specific NLP problems in a highly heuristic manner, yet not from an explicit reasoning perspective. Recently, there have been developments on models that allow reasoning in NLP such as language models, logical models, and so on. The goal of this special issue is to present high-quality contributions that integrate reasoning involved in different areas of natural language processing both at theoretical and/or practical levels. In this article, we give a brief overview on some major aspects of explicating reasoning in NLP and summarize the articles included in this special issue.

Defect reports are generated from various testing and development activities in software engineering. Sometimes two reports are submitted that describe the same problem, leading to duplicate reports. These reports are mostly written in structured natural language, and as such, it is hard to compare two reports for similarity with formal methods. In order to identify duplicates, we investigate using natural language processing (NLP) techniques to support the identification. A prototype tool is developed and evaluated in a case study analyzing defect reports at Sony Ericsson mobile communications. The evaluation shows that about 2/3 of the duplicates can possibly be found using the NLP techniques. Different variants of the techniques provide only minor result differences, indicating a robust technology. User testing shows that the overall attitude towards the technique is positive and that it has a growth potential.

This publication explores how natural language processing (NLP) techniques can be applied to social media text data to map public sentiment and inform development research and policy making. The publication introduces the foundations of natural language analyses and showcases studies that have applied NLP techniques to make progress on the Sustainable Development Goals. It also reviews specific NLP techniques and concepts, supported by two case studies. The first case study analyzes public sentiments on the coronavirus disease (COVID-19) in the Philippines while the second case study explores the public debate on climate change in Australia.

This Chapter discusses the application of Natural Language Processing (NLP) in the legal domain for entity identification and the generation of hierarchy-based applications. NLP techniques, such as Named Entity Recognition (NER) and information extraction, are utilized to analyse legal documents, extract key information, and understand contextual relationships. The integration of NLP facilitates tasks such as legal document summarization, contract analysis, automated document generation, and legal research, thereby enhancing the efficiency and accuracy of legal processes. The creation of hierarchical structures within documents, language translation, sentiment analysis, and compliance monitoring further contribute to the comprehensive utilization of NLP in the legal field. The abstract highlights the transformative impact of NLP in streamlining legal workflows, improving information retrieval, and ensuring compliance with evolving legal standards. Most judicial systems in the world, centered around the Supreme Court as the highest-level court, grapples with a substantial caseload, receiving over 7,500 cases annually but hearing fewer than 150. The Supreme Court's unique role in interpreting the constitutionality of laws and establishing precedents underscores its significant influence. Challenges arise from the overwhelming caseload, leading to increased use of plea bargains and potential concerns about justice. To address these issues, a proposed research initiative suggests employing machine learning and natural language processing to accelerate Supreme Court decisions, aiming to uncover pivotal aspects that greatly influence the outcomes, and enhance our comprehension on India legal system's functioning and constraints. This chapter presents a methodology for sentiment-based summarization of legal documents using Natural Language Processing (NLP) techniques. The process involves pre-processing the text, conducting sentiment analysis to label sentences as positive, negative, or neutral, and then summarizing the document while incorporating the identified sentiments. Special attention is paid to legal-specific considerations such as terminology and context.

Social media, a buzz term in the modern world, refers to various online platforms like social networks, forums, blogs and blog comments, microblogs, wikis, media sharing platforms, social bookmarks through which communication between individuals, communities, or groups takes place. People over social media do not only share their ideas and opinions, but it has become an important source through which businesses promote their products. Analyzing huge data generated over social media is useful in various tasks like analyzing customer trends, forecast sales, understanding opinions of people on different hot topics, views of customers about services/products, and many more. Different natural language processing (NLP) techniques are used for crawling and processing social media data to get useful insights out of this. In this chapter, the focus is on various NLP techniques used to process the social media data. Challenges faced by NLP techniques to process social media data are also put forward in this chapter.

Executable files still remain popular to compromise the endpoint computers. These executable files are often obfuscated to avoid anti-virus programs. To examine all suspicious files from the Internet, dynamic analysis requires too much time. Therefore, a fast filtering method is required. With the recent development of natural language processing (NLP) techniques, printable strings became more effective to detect malware. The combination of the printable strings and NLP techniques can be used as a filtering method. In this paper, we apply NLP techniques to malware detection. This paper reveals that printable strings with NLP techniques are effective for detecting malware in a practical environment. Our dataset consists of more than 500,000 samples obtained from multiple sources. Our experimental results demonstrate that our method is effective to not only subspecies of the existing malware, but also new malware. Our method is effective against packed malware and anti-debugging techniques.