Medical Image Segmentation by using Active Flow Model with Simulated Annealing

Aggregating multi-level feature representation plays a critical role in achieving robust volumetric medical image segmentation, which is important for the auxiliary diagnosis and treatment. Unlike the recent neural architecture search (NAS) methods that typically searched the optimal operators in each network layer, but missed a good strategy to search for feature aggregations, this paper proposes a novel NAS method for 3D medical image segmentation, named UXNet, which searches both the scale-wise feature aggregation strategies as well as the block-wise operators in the encoder-decoder network. UXNet has several appealing benefits. (1) It significantly improves flexibility of the classical UNet architecture, which only aggregates feature representations of encoder and decoder in equivalent resolution. (2) A continuous relaxation of UXNet is carefully designed, enabling its searching scheme performed in an efficient differentiable manner. (3) Extensive experiments demonstrate the effectiveness of UXNet compared with recent NAS methods for medical image segmentation. The architecture discovered by UXNet outperforms existing state-of-the-art models in terms of Dice on several public 3D medical image segmentation benchmarks, especially for the boundary locations and tiny tissues. The searching computational complexity of UXNet is cheap, enabling to search a network with best performance less than 1.5 days on two TitanXP GPUs.

Medical image segmentation is a fundamental task in medical image analysis, playing a crucial role in disease diagnosis, treatment planning, and clinical decision-making. Accurate segmentation of anatomical structures, such as blood vessels, organs, and lesions, is essential for reliable medical interpretations. However, existing segmentation models often face challenges in effectively capturing both local and global features within medical images. Traditional convolutional neural networks (CNNs) excel at extracting fine-grained local features but struggle to model long-range dependencies due to their limited receptive fields. Conversely, transformer-based models can capture global contextual relationships but often fail to preserve detailed local structures, leading to suboptimal segmentation performance. The purpose of this study is to develop SEFormer, a novel hybrid network that integrates SENet, ResNet, and Transformer to enhance medical image segmentation. SEFormer aims to effectively capture both local and global features, addressing the limitations of traditional CNNs and transformer-based models.SENet is incorporated to recalibrate feature maps by adaptively emphasizing informative features, thereby compensating for the global representation limitations of CNNs. Meanwhile, the ResNet backbone ensures deep feature extraction while maintaining computational efficiency. Additionally, the Transformer module is introduced to capture long-range dependencies and enhance contextual awareness, complementing the local feature extraction capabilities of CNNs. This hybrid approach allows SEFormer to balance fine-grained spatial details with broader contextual information, leading to more precise segmentation results.Furthermore, to mitigate information loss during feature extraction and ensure a more complete and hierarchical representation of image information, we introduce a feature pyramid structure inspired by multi-scale image pyramid models. By progressively increasing the receptive field across different scales and employing skip connections, SEFormer effectively fuses multi-scale local and global features at each stage of the pyramid. This hierarchical fusion mechanism ensures a richer and more robust feature representation, which is particularly beneficial for segmenting complex medical structures such as blood vessels. We evaluate SEFormer on the CHASE_DB1 dataset, a widely used benchmark for retinal vessel segmentation. Experimental results demonstrate that SEFormer outperforms existing state-of-the-art segmentation methods, achieving a 3.25% improvement in segmentation accuracy. Additionally, we conduct ablation studies to verify the contributions of different components within SEFormer. The results show that incorporating SENet enhances feature recalibration and channel attention, while the Transformer module significantly improves global context awareness. The feature pyramid structure further contributes to performance gains by ensuring a multi-scale representation of vascular structures. Compared to conventional CNN-based methods, our approach achieves better segmentation accuracy with improved robustness to variations in vessel thickness, noise, and image contrast. Furthermore, SEFormer maintains computational efficiency, making it suitable for real-world clinical applications where both accuracy and processing speed are critical. SEFormer provides an efficient and accurate approach for medical image segmentation by leveraging the complementary strengths of CNNs, SENet, and Transformers while integrating a feature pyramid structure to maximize feature representation. Future research directions include extending SEFormer to other medical imaging modalities, such as CT and MRI scans, as well as exploring further optimization techniques to reduce computational costs while maintaining high segmentation performance. Additionally, integrating SEFormer with active learning frameworks could further improve segmentation performance by leveraging expert-annotated data more efficiently.

An efficient neural network based method for medical image segmentation

Medical image segmentation is a critical application of computer vision in the analysis of medical images. Its primary objective is to isolate regions of interest in medical images from the background, thereby assisting clinicians in accurately identifying lesions, their sizes, locations, and their relationships with surrounding tissues. However, compared to natural images, medical images present unique challenges, such as low resolution, poor contrast, inconsistency, and scattered target regions. Furthermore, the accuracy and stability of segmentation results are subject to more stringent requirements. In recent years, with the widespread application of Convolutional Neural Networks (CNNs) in computer vision, deep learning-based methods for medical image segmentation have become a focal point of research. This paper categorizes, reviews, and summarizes the current representative methods and research status in the field of medical image segmentation. A comparative analysis of relevant experiments is presented, along with an introduction to commonly used public datasets, performance evaluation metrics, and loss functions in medical image segmentation. Finally, potential future research directions and development trends in this field are predicted and analyzed.

Segmentation of medical images is an important step in many clinical and diagnostic imaging applications. Medical images present many challenges for automated segmentation including poor contrast at tissue boundaries. Traditional segmentation methods based solely on information from the image do not work well in such cases. Statistical shape information for objects in medical images are easy to obtain. In this paper, we propose a graph cuts-based segmentation method for medical images that incorporates statistical shape priors to increase robustness. Our proposed method is able to deal with complex shapes and shape variations while taking advantage of the globally efficient optimization by graph cuts. We demonstrate the effectiveness of our method on kidney images without strong boundaries.

Learning with limited annotations: A survey on deep semi-supervised learning for medical image segmentation

The purpose of medical image segmentation is to divides the lesions image with a special meaning and background regional. The characteristics of medical images are generally more complex. There is often overlap between different regions, the edge of the area is vague. Research based on fuzzy clustering method for medical image segmentation, fuzzy C-means clustering and fuzzy kernel clustering methods were studied and discussed fully considered the spatial information, the single objective problem conversion into multi-objective problem. The experimental results show that the method use in medical image segmentation achieved good results.

It needs set parameters on image segmentation based on PCNN (Pulse Coupled Neural Network) now. This paper points out the new method for medical image segmentation based on improved PCNN and Tsallis entropy. The new methods can automatically segment the medical images without selecting the PCNN parameters. It gets the best results with combining with the Tsallis entropy. The new method is very useful for PCNN application in the medical images segmentation.

Segmenting medical images via explicit–implicit attention aggregation

A wavelet transform-based image segmentation method

FSA-Net: Rethinking the attention mechanisms in medical image segmentation from releasing global suppressed information

Unsupervised domain adaption (UDA), which aims to enhance the segmentation performance of deep models on unlabeled data, has recently drawn much attention. In this paper, we propose a novel UDA method (namely DLaST) for medical image segmentation via disentanglement learning and self-training. Disentanglement learning factorizes an image into domain-invariant anatomy and domain-specific modality components. To make the best of disentanglement learning, we propose a novel shape constraint to boost the adaptation performance. The self-training strategy further adaptively improves the segmentation performance of the model for the target domain through adversarial learning and pseudo label, which implicitly facilitates feature alignment in the anatomy space. Experimental results demonstrate that the proposed method outperforms the state-of-the-art UDA methods for medical image segmentation on three public datasets, i.e., a cardiac dataset, an abdominal dataset and a brain dataset. The code will be released soon.

DSEU-net: A novel deep supervision SEU-net for medical ultrasound image segmentation

Dynamic domain generalization for medical image segmentation.

Fully convolutional neural networks like U-Net have been the state-of-the-art methods in medical image segmentation. Practically, a network is highly specialized and trained separately for each segmentation task. Instead of a collection of multiple models, it is highly desirable to learn a universal data representation for different tasks, ideally a single model with the addition of a minimal number of parameters steered to each task. Inspired by the recent success of multi-domain learning in image classification, for the first time we explore a promising universal architecture that handles multiple medical segmentation tasks and is extendable for new tasks, regardless of different organs and imaging modalities. Our 3D Universal U-Net (3D U$^2$-Net) is built upon separable convolution, assuming that {\it images from different domains have domain-specific spatial correlations which can be probed with channel-wise convolution while also share cross-channel correlations which can be modeled with pointwise convolution}. We evaluate the 3D U$^2$-Net on five organ segmentation datasets. Experimental results show that this universal network is capable of competing with traditional models in terms of segmentation accuracy, while requiring only about $1\%$ of the parameters. Additionally, we observe that the architecture can be easily and effectively adapted to a new domain without sacrificing performance in the domains used to learn the shared parameterization of the universal network. We put the code of 3D U$^2$-Net into public domain. \url{https://github.com/huangmozhilv/u2net_torch/}