Multi-grade brain tumor classification using deep CNN with extensive data augmentation

Coronavirus (COVID-19) was first observed in Wuhan, China, and quickly propagated worldwide. It is considered the supreme crisis of the present era and one of the most crucial hazards threatening worldwide health. Therefore, the early detection of COVID-19 is essential. The common way to detect COVID-19 is the reverse transcription-polymerase chain reaction (RT-PCR) test, although it has several drawbacks. Computed tomography (CT) scans can enable the early detection of suspected patients, however, the overlap between patterns of COVID-19 and other types of pneumonia makes it difficult for radiologists to diagnose COVID-19 accurately. On the other hand, deep learning (DL) techniques and especially the convolutional neural network (CNN) can classify COVID-19 and non-COVID-19 cases. In addition, DL techniques that use CT images can deliver an accurate diagnosis faster than the RT-PCR test, which consequently saves time for disease control and provides an efficient computer-aided diagnosis (CAD) system. The shortage of publicly available datasets of CT images, makes the CAD system’s design a challenging task. The CAD systems in the literature are based on either individual CNN or two-fused CNNs; one used for segmentation and the other for classification and diagnosis. In this article, a novel CAD system is proposed for diagnosing COVID-19 based on the fusion of multiple CNNs. First, an end-to-end classification is performed. Afterward, the deep features are extracted from each network individually and classified using a support vector machine (SVM) classifier. Next, principal component analysis is applied to each deep feature set, extracted from each network. Such feature sets are then used to train an SVM classifier individually. Afterward, a selected number of principal components from each deep feature set are fused and compared with the fusion of the deep features extracted from each CNN. The results show that the proposed system is effective and capable of detecting COVID-19 and distinguishing it from non-COVID-19 cases with an accuracy of 94.7%, AUC of 0.98 (98%), sensitivity 95.6%, and specificity of 93.7%. Moreover, the results show that the system is efficient, as fusing a selected number of principal components has reduced the computational cost of the final model by almost 32%.

The leather industry plays a crucial role in the production of high-quality leather products to remain competitive in the market. Due to various reasons such as material handling and turning, leather defects can appear at different stages of the production process. This paper proposed deep learning techniques, specifically transfer learning, deep convolutional neural networks (D-CNN), and ensemble learning for automating leather defect detection and classification. The dataset was taken from the open source Kaggle. The dataset was preprocessed from the beginning. However, we performed Error Level Analysis (ELA) to detect possible changes or fraud in the image. We also used data augmentation techniques (resizing, rescaling, flipping, rotation, zooming, and contrasting) on the dataset to improve the model performance. This study investigated deep learning architectures for automatic leather defect detection, comparing them with seven deep convolutional neural networks (D-CNN) models and transfer learning architectures. Furthermore, we introduce and evaluate two novel ensemble models: MER built on transfer learning architecture (MobileNetV2, EfficientNetB0, and ResNet50) and AZL built on D-CNN architecture (AlexNet, ZfNet, and LeNet). A key contribution of this study is the demonstration of significant performance improvements achieved by strategically integrating squeeze and excitation and label smoothing techniques into transfer learning, D-CNN, and ensemble frameworks. Our proposed MER ensemble method achieves a state-of-the-art of 96.39% for leather defect detection. The proposed model was evaluated using performance metrics including precision, recall, F1-score, AUC, ROC, and Matthews Correlation Coefficient (MCC). Additionally, Grad-CAM was employed for explainable AI to visualize and interpret the model’s decision-making process. Comparative analysis against separate transfer learning and D-CNN models fails to establish the superior performance of our MER ensemble, which highlights the potential to significantly advance automated quality inspection in leather production. This study provides insights into evaluating the best deep learning techniques for leather defect classification, paving the way for more accurate, efficient, and reliable industrial applications. Proposes a robust deep learning-based framework for automated leather defect detection using transfer learning, deep CNNs, and two novel ensemble models (MER and AZL), enhanced with squeeze-and-excitation and label smoothing techniques. Achieves state-of-the-art performance with the proposed MER ensemble model, achieve 96.39% accuracy, and demonstrates superior results across precision, recall, F1-score, AUC–ROC, and MCC. Integrates Error Level Analysis (ELA), extensive data augmentation, and Grad-CAM–based explainable AI to ensure data reliability, improve generalization, and provide transparent visual interpretation of defect regions for industrial quality inspection.

Accurate segmentation and delineation of the sub-tumor regions are very challenging tasks due to the nature of the tumor. Traditionally, convolutional neural networks (CNNs) have succeeded in achieving most promising performance for the segmentation of brain tumor; however, handcrafted features remain very important in identification of tumor's boundary regions accurately. The present work proposes a robust deep learning-based model with three different CNN architectures along with pre-defined handcrafted features for brain tumor segmentation, mainly to find out more prominent boundaries of the core and enhanced tumor regions. Generally, automatic CNN architecture does not use the pre-defined handcrafted features because it extracts the features automatically. In this present work, several pre-defined handcrafted features are computed from four MRI modalities (T2, FLAIR, T1c, and T1) with the help of additional handcrafted masks according to user interest and fed to the convolutional features (automatic features) to improve the overall performance of the proposed CNN model for tumor segmentation. Multi-pathway CNN is explored in this present work along with single-pathway CNN, which extracts simultaneously both local and global features to identify the accurate sub-regions of the tumor with the help of handcrafted features. The present work uses a cascaded CNN architecture, where the outcome of a CNN is considered as an additional input information to next subsequent CNNs. To extract the handcrafted features, convolutional operation was applied on the four MRI modalities with the help of several pre-defined masks to produce a predefined set of handcrafted features. The present work also investigates the usefulness of intensity normalization and data augmentation in pre-processing stage in order to handle the difficulties related to the imbalance of tumor labels. The proposed method is experimented on the BraST 2018 datasets and achieved promising results than the existing (currently published) methods with respect to different metrics such as specificity, sensitivity, and dice similarity coefficient (DSC) for complete, core, and enhanced tumor regions. Quantitatively, a notable gain is achieved around the boundaries of the sub-tumor regions using the proposed two-pathway CNN along with the handcrafted features. Graphical Abstract This data is mandatory. Please provide.

Deep-learning approaches with data augmentation have been widely used when developing neuroimaging-based computer-aided diagnosis (CAD) systems. To prevent the inflated diagnostic performance caused by data leakage, a correct cross-validation (CV) method should be employed, but this has been still overlooked in recent deep-learning-based CAD studies. The goal of this study was to investigate the impact of correct and incorrect CV methods on the diagnostic performance of deep-learning-based CAD systems after data augmentation. To this end, resting-state electroencephalogram (EEG) data recorded from post-traumatic stress disorder patients and healthy controls were augmented using a cropping method with different window sizes, respectively. Four different CV approaches were used to estimate the diagnostic performance of the CAD system, i.e., subject-wise CV (sCV), overlapped sCV (oSCV), trial-wise CV (tCV), and overlapped tCV (otCV). Diagnostic performances were evaluated using two deep-learning models based on convolutional neural network. Data augmentation can increase the performance with all CVs, but inflated diagnostic performances were observed when using incorrect CVs (tCV and otCV) due to data leakage. Therefore, the correct CV (sCV and osCV) should be used to develop a deep-learning-based CAD system. We expect that our investigation can provide deep-insight for researchers who plan to develop neuroimaging-based CAD systems for psychiatric disorders using deep-learning algorithms with data augmentation.

Early and accurate identification of brain tumors is essential for determining effective treatment strategies and improving patient outcomes. Artificial intelligence (AI) and deep learning (DL) techniques have shown promise in automating diagnostic tasks based on magnetic resonance imaging (MRI). This study evaluates the performance of four pre-trained deep convolutional neural network (CNN) architectures for the automatic multi-class classification of brain tumors into four categories: Glioma, Meningioma, Pituitary, and No Tumor. The proposed approach utilizes the publicly accessible Brain Tumor MRI Msoud dataset, consisting of 7023 images, with 5712 provided for training and 1311 for testing. To assess the impact of data availability, subsets containing 25%, 50%, 75%, and 100% of the training data were used. A stratified five-fold cross-validation technique was applied. The CNN architectures evaluated include DeiT3_base_patch16_224, Xception41, Inception_v4, and Swin_Tiny_Patch4_Window7_224, all fine-tuned using transfer learning. The training pipeline incorporated advanced preprocessing and image data augmentation techniques to enhance robustness and mitigate overfitting. Among the models tested, Swin_Tiny_Patch4_Window7_224 achieved the highest classification Accuracy of 99.24% on the test set using 75% of the training data. This model demonstrated superior generalization across all tumor classes and effectively addressed class imbalance issues. Furthermore, we deployed and benchmarked the best-performing DL model on embedded AI platforms (Jetson AGX Xavier and Orin Nano), demonstrating their capability for real-time inference and highlighting their feasibility for edge-based clinical deployment. The results highlight the strong potential of pre-trained deep CNN and transformer-based architectures in medical image analysis. The proposed approach provides a scalable and energy-efficient solution for automated brain tumor diagnosis, facilitating the integration of AI into clinical workflows.

The complexity of brain tumors highlights the critical need for advanced computer‐aided diagnosis (CAD) tools to support surgeons in clinical decision‐making and improve patient outcomes. This paper introduces a novel deep learning model for the multiclass classification of brain tumors using magnetic resonance imaging (MRI), offering significant advancements in feature extraction and classification accuracy. The proposed model comprises three key components: (1) a fine‐tuned EfficientNetB7 convolutional neural network (CNN), adapted through transfer learning by freezing the initial layers and retraining subsequent layers to optimize feature extraction from MR images; (2) a channel attention module that refines extracted feature maps, emphasizing essential features for accurate tumor detection; and (3) a fully connected classifier, optimized through grid search, to achieve precise multiclass tumor classification. Additionally, hyperparameter tuning and data augmentation techniques enhance generalization and model robustness. Experimental results confirm the model’s superior performance, outperforming recent approaches in multiclass and binary classification scenarios, underscoring its potential to advance brain tumor diagnosis and treatment.

In the realm of computer vision, image classification is a critical issue with many applications, including multimedia content analysis, security and surveillance, and medical imaging. The accuracy of image classification algorithms has considerably increased with the development of deep learning. The discipline of image classification has dramatically benefited from the usage of pre-trained Convolutional Neural Network (CNN) models. In this study, we perform image classification on the Wang dataset composed of 1000 images separated into ten categories, using six different pre-trained CNN models. The research made use of pre-trained versions of VGG16, Densenet, Mobilenet, Inception V3, Resnet50, and Xception models. We assessed the model performances in terms of training and testing accuracy. Testing accuracies for ten unique batches of data were calculated and averaged out. Densenet outperformed state-of-the-art models like Xception by a small margin, mainly due to low data availability. The findings of this study show how pre-trained models have advanced the field of image classification and shed light on how well these models perform in diverse image classification tasks. This study can serve as a valuable reference for researchers and practitioners in the field of computer vision and deep learning and help inform their choices when selecting pre-trained models for image classification, depending on their needs, while also considering data availability and computational constraints.

This work presents the development and evaluation of Artificial Intelligence (AI) models for the automatic classification of brain tumors in Magnetic Resonance Imaging (MRI) scans. Several deep learning architectures were implemented and compared, including VGG-19, ResNet50, EfficientNetB3, Xception, MobileNetV2, DenseNet201, InceptionV3, Vision Transformer (ViT), and an Ensemble model. The models were developed in Python (version 3.12.4) using the Keras and TensorFlow frameworks and trained on a public Brain Tumor MRI dataset containing 7023 images. Data augmentation and hyperparameter optimization techniques were applied to improve model generalization. The results showed high classification performance, with accuracies ranging from 89.47% to 98.17%. The Vision Transformer achieved the best performance, reaching 98.17% accuracy, outperforming traditional Convolutional Neural Network (CNN) architectures. Explainable AI (XAI) methods Grad-CAM, LIME, and Occlusion Sensitivity were employed to assess model interpretability, showing that the models predominantly focused on tumor regions. The proposed approach demonstrated the effectiveness of AI-based systems in supporting early diagnosis of brain tumors, reducing analysis time and assisting healthcare professionals.

Emotions expressed by humans can be identified from facial expressions, speech signals, or physiological signals. Among them, the use of physiological signals for emotion classification is a notable emerging area of research. In emotion recognition, a person’s electrocardiogram (ECG) and galvanic skin response (GSR) signals cannot be manipulated, unlike facial and voice signals. Moreover, wearables such as smartwatches and wristbands enable the detection of emotions in people’s naturalistic environment. During the COVID-19 pandemic, it was necessary to detect people’s emotions in order to ensure that appropriate actions were taken according to the prevailing situation and achieve societal balance. Experimentally, the duration of the emotion stimulus period and the social and non-social contexts of participants influence the emotion classification process. Hence, classification of emotions when participants are exposed to the elicitation process for a longer duration and taking into consideration the social context needs to be explored. This work explores the classification of emotions using five pretrained convolutional neural network (CNN) models: MobileNet, NASNetMobile, DenseNet 201, InceptionResnetV2, and EfficientNetB7. The continuous wavelet transform (CWT) coefficients were detected from ECG and GSR recordings from the AMIGOS database with suitable filtering. Scalograms of the sum of frequency coefficients versus time were obtained and converted into images. Emotions were classified using the pre-trained CNN models. The valence and arousal emotion classification accuracy obtained using ECG and GSR data were, respectively, 91.27% and 91.45% using the InceptionResnetV2 CNN classifier and 99.19% and 98.39% using the MobileNet CNN classifier. Other studies have not explored the use of scalograms to represent ECG and GSR CWT features for emotion classification using deep learning models. Additionally, this study provides a novel classification of emotions built on individual and group settings using ECG data. When the participants watched long-duration emotion elicitation videos individually and in groups, the accuracy was around 99.8%. MobileNet had the highest accuracy and shortest execution time. These subject-independent classification methods enable emotion classification independent of varying human behavior.

Categorizing brain cancers, including glioma, meningioma, and pituitary tumors, based on magnetic resonance imaging (MRI) images presents a significant challenge. Deep learning and machine learning techniques have shown promise in enhancing image categorization. To address this challenge, we leverage the power of the optimized ResNet50 model. Our approach involves classifying medical images using Convolutional Neural Network (CNN) features, which are then compared with the ResNet50 model. The primary goal is to detect brain tumors at an early stage using an advanced deep-learning model. We utilize an accessible dataset from Figshare, containing MRI images of the three distinct categories of brain tumors. Existing brain tumor models face limitations in handling multi-class problems and early-stage diagnosis. Therefore, we propose a fully automated approach employing Convolutional Neural Networks (CNN) to extract diverse properties from brain MRI scans. This method aims to provide accurate tumor diagnosis, even with a high number of classes and limited information in MRI data. Our proposed model involves the creation of identification blocks within a four-layered primary architecture, followed by testing and assessment of the interconnected layers. The results demonstrate that our model outperforms existing methods, achieving an impressive overall classification accuracy of 99.03%,

Brain tumor image segmentation is one of the most critical tasks in medical imaging for diagnosis, treatment planning, and prognosis. Traditional methods for brain tumor image segmentation are mostly based on Convolution Neural Network (CNN), which have been proved very powerful but still have limitations to effectively capture long-range dependencies and complex spatial hierarchies in MRI images. Variability in the shape, size, and location of tumors may affect the performance and may get stuck into suboptimal outcomes. In these regards, new encoder-decoder architecture with the VisionTranscoder(ViT) is proposed, to enhance brain tumor detection and classification. The proposed VisionTranscoder exploits a transformer's ability in modeling global context through self-attention mechanisms, providing more inclusive interpretation of the intricate patterns in medical images and classification by capturing both local and global features. The proposed VisionTranscoder maintains the Vision Transformer in its encoder for processing images as sequences of patches to capture global dependencies often outside the view of traditional CNNs. Then the segmentation map is rebuilt at a high level of fidelity with the decoder through upsampling and skips connections to maintain detailed spatial information. The risk of overfitting is hugely reduced by design and advanced regularization techniques with extensive data augmentation. The dataset contains 7,023 human brain MRI images, all of which are in four different classes: glioma, meningioma, no tumor, and pituitary. Images from the 'no tumor' class, indicating an MRI scan without any detectable tumor, were taken from the Br35H dataset . The results show the efficiency of VisionTranscoder over a wide set of brain MRI scans, producing an accuracy of 98.5% with a loss of 0.05. This performance underlines the ability of it to accurately segment and classify a brain tumor without overfitting.

Brain tumour is a serious disease, and the number of people who are dying due to brain tumours is increasing. Manual tumour diagnosis from magnetic resonance images (MRIs) is a time consuming process and is insufficient for accurately detecting, localizing, and classifying the tumour type. This research proposes a novel two-phase multi-model automatic diagnosis system for brain tumour detection and localization. In the first phase, the system structure consists of preprocessing, feature extraction using a convolutional neural network (CNN), and feature classification using the error-correcting output codes support vector machine (ECOC-SVM) approach. The purpose of the first system phase is to detect brain tumour by classifying the MRIs into normal and abnormal images. The aim of the second system phase is to localize the tumour within the abnormal MRIs using a fully designed five-layer region-based convolutional neural network (R-CNN). The performance of the first phase was assessed using three CNN models, namely, AlexNet, Visual Geometry Group (VGG)-16, and VGG-19, and a maximum detection accuracy of 99.55% was achieved with AlexNet using 349 images extracted from the standard Reference Image Database to Evaluate Response (RIDER) Neuro MRI database. The brain tumour localization phase was evaluated using 804 3D MRIs from the Brain Tumor Segmentation (BraTS) 2013 database, and a DICE score of 0.87 was achieved. The empirical work proved the outstanding performance of the proposed deep learning-based system in tumour detection compared to other non-deep-learning approaches in the literature. The obtained results also demonstrate the superiority of the proposed system concerning both tumour detection and localization.

Brain tumors are one of the most threatening diseases to human health. Accurate identification of the type of brain tumor is essential for patients and doctors. An automated brain tumor diagnosis system based on Magnetic Resonance Imaging (MRI) can help doctors to identify the type of tumor and reduce their workload, so it is vital to improve the performance of such systems. Due to the challenge of collecting sufficient data on brain tumors, utilizing pre-trained Convolutional Neural Network (CNN) models for brain tumors classification is a feasible approach. The study proposes a novel brain tumor classification system, called EFF_D_SVM, which is developed on the basic of pre-trained EfficientNetB0 model. Firstly, a new feature extraction module EFF_D was proposed, in which the classification layer of EfficientNetB0 was replaced with two dropout layers and two dense layers. Secondly, the EFF_D model was fine-tuned using Softmax, and then features of brain tumor images were extracted using the fine-tuned EFF_D. Finally, the features were classified using Support Vector Machine (SVM). In order to verify the effectiveness of the proposed brain tumor classification system, a series of comparative experiments were carried out. Moreover, to understand the extracted features of the brain tumor images, Grad-CAM technology was used to visualize the proposed model. Furthermore, cross-validation was conducted to verify the robustness of the proposed model. The evaluation metrics including accuracy, F1-score, recall, and precision were used to evaluate proposed system performance. The experimental results indicate that the proposed model is superior to other state-of-the-art models.

As part of an effort to develop intelligent agriculture, new methods for enhancing the quality of vegetables are being continually developed. In recent years, the Convolutional Neural Network (CNN) has shown to be the most successful and extensively used approach for identifying the quality of pre-trained vegetables. However, this method is time-consuming due to the scarcity of truly large, significant datasets. Using a pre-trained CNN model as a feature extractor is a straightforward method for utilizing CNNs' capabilities without investing time in training. While, Support Vector Machine (SVM excels at processing data with tiny dimensions and significantly larger instances. SVM more accurately classifies the flatten/vector feature supplied by the CNN fully connected layer with small dimensions. In addition, implementing Data Augmentation (DA) and Weighted Class (WC) for data variety and class imbalance reduction can improve CNN-SVM performance. The research results show highest accuracy during training always achieves 100% across all experimental options. With an average accuracy of 69.66% in the testing process and 92.51% in the prediction process for all data, the experimental findings demonstrate that CNN-SVM outperforms CNN in terms of accuracy performance in all possible experiments, with or without WC and or DA approach.

Brain tumor is one of the most aggressive diseases nowadays, resulting in a very short life span if it is diagnosed at an advanced stage. The treatment planning phase is thus essential for enhancing the quality of life for patients. The use of Magnetic Resonance Imaging (MRI) in the diagnosis of brain tumors is extremely widespread, but the manual interpretation of large amounts of images requires considerable effort and is prone to human errors. Hence, an automated method is necessary to identify the most common brain tumors. Convolutional Neural Network (CNN) architectures are successful in image classification due to their high layer count, which enables them to conceive the features effectively on their own. The tuning of CNN hyperparameters is critical in every dataset since it has a significant impact on the efficiency of the training model. Given the high dimensionality and complexity of the data, manual hyperparameter tuning would take an inordinate amount of time, with the possibility of failing to identify the optimal hyperparameters. In this paper, we proposed a Bayesian Optimization-based efficient hyperparameter optimization technique for CNN. This method was evaluated by classifying 3064 T-1-weighted CE-MRI images into three types of brain tumors (Glioma, Meningioma, and Pituitary). Based on Transfer Learning, the performance of five well-recognized deep pre-trained models is compared with that of the optimized CNN. After using Bayesian Optimization, our CNN was able to attain 98.70% validation accuracy at best without data augmentation or cropping lesion techniques, while VGG16, VGG19, ResNet50, InceptionV3, and DenseNet201 achieved 97.08%, 96.43%, 89.29%, 92.86%, and 94.81% validation accuracy, respectively. Moreover, the proposed model outperforms state-of-the-art methods on the CE-MRI dataset, demonstrating the feasibility of automating hyperparameter optimization.