A problem of globally asymptotically stable control design is investigated for a class of high-order uncertain nonlinear systems. These systems, unlike the existing results, have double control input channels; that is, the control input directly affects two one-dimensional subsystems. This makes the existing methods of control design inapplicable or the control design problem difficult to solve, and therefore, it is of interest to explore a new control design method to solve the control design of high-order nonlinear systems with multiple control input channels. First, an effective feedback transformation is introduced. Hence, this control design problem under appropriate assumptions can be transformed into one with a single control input channel. Then, using existing results, particularly, the method of adding a power integrator, a methodology is proposed to design the globally asymptotically stable controller for the nonlinear systems under investigation. Although the systems studied in the paper are a special case of high-order nonlinear systems with multiple control input channels, the results obtained in the paper, while unavoidably having certain limitations, will provide a reference and guidance in tackling the general case. Finally, a simulation is provided to verify the effectiveness of the theoretical results obtained.