Phase measuring deflectometry for thin actuated mirrors

he wider health impacts of the coronavirus disease 2019 (COVID-19) pandemic are of increasing concern, with an increase in rates of non-COVID-19 excess mortality observed. In England and the United States, the early pandemic was accompanied by a decline in patient visits to Emergency Departments (EDs), including those for cardiac diseases. 1, The decline may have been influenced by patient's reluctance to visit hospital due to the public health messages to protect National Health Service capacity, concerns about the risk of coronavirus infection, or difficulties in accessing medical care. The impact of delayed or nonpresentation to EDs with suspected cardiac disease on cardiac mortality is unknown. In this study, we used instrumental variable analysis to estimate the effects of reduced ED visits on cardiac mortality in England.

HippocampusVolume 6, Issue 1 p. 3-8 Topical Article Intracellular studies of heterosynaptic long-term depression (LTD) in CA1 of hippocampal slices Michael F. Barry, Michael F. Barry Department of Physiology, University College London, London, United KingdomSearch for more papers by this authorR.M. Vickery, R.M. Vickery Department of Physiology, University College London, London, United KingdomSearch for more papers by this authorS.R. Bolsover, S.R. Bolsover Department of Physiology, University College London, London, United KingdomSearch for more papers by this authorLynn J. Bindman, Corresponding Author Lynn J. Bindman Department of Physiology, University College London, London, United KingdomDepartment of Physiology, University College London, London WC1E 6BI, UKSearch for more papers by this author Michael F. Barry, Michael F. Barry Department of Physiology, University College London, London, United KingdomSearch for more papers by this authorR.M. Vickery, R.M. Vickery Department of Physiology, University College London, London, United KingdomSearch for more papers by this authorS.R. Bolsover, S.R. Bolsover Department of Physiology, University College London, London, United KingdomSearch for more papers by this authorLynn J. Bindman, Corresponding Author Lynn J. Bindman Department of Physiology, University College London, London, United KingdomDepartment of Physiology, University College London, London WC1E 6BI, UKSearch for more papers by this author First published: 1996 https://doi.org/10.1002/(SICI)1098-1063(1996)6:1<3::AID-HIPO2>3.0.CO;2-SCitations: 9AboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onFacebookTwitterLinkedInRedditWechat Citing Literature Volume6, Issue11996Pages 3-8 RelatedInformation

BJU InternationalVolume 89, Issue 7 p. 793-794 Chronic ethanol consumption impairs adrenoceptor- and purinoceptor-mediated relaxations in isolated rat detrusor smooth muscle R.C. Calvert MA, MB, Bchir, MRCS, R.C. Calvert MA, MB, Bchir, MRCS Research Registrar Departments of Urology and Clinical Biochemistry, Royal Free and University College Medical School (Royal Free Campus), University College London, UKSearch for more papers by this authorF.C.L. Banks MB, BS, FRCS, F.C.L. Banks MB, BS, FRCS Research Registrar Departments of Urology and Clinical Biochemistry, Royal Free and University College Medical School (Royal Free Campus), University College London, UKSearch for more papers by this authorC.S. Thompson PhD, C.S. Thompson PhD Senior Research Fellow Departments of Urology and Clinical Biochemistry, Royal Free and University College Medical School (Royal Free Campus), University College London, UKSearch for more papers by this authorD.P. Mikhailidis MB, BS, FRCPath, MD, D.P. Mikhailidis MB, BS, FRCPath, MD Reader Departments of Urology and Clinical Biochemistry, Royal Free and University College Medical School (Royal Free Campus), University College London, UKSearch for more papers by this authorR.J. Morgan MA, BM, Bchir, FRCS, R.J. Morgan MA, BM, Bchir, FRCS Consultant Urological Surgeon Departments of Urology and Clinical Biochemistry, Royal Free and University College Medical School (Royal Free Campus), University College London, UKSearch for more papers by this author R.C. Calvert MA, MB, Bchir, MRCS, R.C. Calvert MA, MB, Bchir, MRCS Research Registrar Departments of Urology and Clinical Biochemistry, Royal Free and University College Medical School (Royal Free Campus), University College London, UKSearch for more papers by this authorF.C.L. Banks MB, BS, FRCS, F.C.L. Banks MB, BS, FRCS Research Registrar Departments of Urology and Clinical Biochemistry, Royal Free and University College Medical School (Royal Free Campus), University College London, UKSearch for more papers by this authorC.S. Thompson PhD, C.S. Thompson PhD Senior Research Fellow Departments of Urology and Clinical Biochemistry, Royal Free and University College Medical School (Royal Free Campus), University College London, UKSearch for more papers by this authorD.P. Mikhailidis MB, BS, FRCPath, MD, D.P. Mikhailidis MB, BS, FRCPath, MD Reader Departments of Urology and Clinical Biochemistry, Royal Free and University College Medical School (Royal Free Campus), University College London, UKSearch for more papers by this authorR.J. Morgan MA, BM, Bchir, FRCS, R.J. Morgan MA, BM, Bchir, FRCS Consultant Urological Surgeon Departments of Urology and Clinical Biochemistry, Royal Free and University College Medical School (Royal Free Campus), University College London, UKSearch for more papers by this author First published: 01 May 2002 https://doi.org/10.1046/j.1464-410X.2002.t01-4-02801.xCitations: 4Read the full textAboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onFacebookTwitterLinkedInRedditWechat Citing Literature Volume89, Issue7May 2002Pages 793-794 RelatedInformation

Figure correction of thin x-ray telescope mirrors may be critical for future missions that require high angular resolution and large collecting areas. One promising method of providing figure correction is to use stress generated via ion implantation. Since stress-based figure correction strategies cannot correct high spatial frequency errors, it is critical to obtain glass with only low spatial frequency error. One method is thermal gas bearing slumping, where glass is softened while floating on thin films of gas. This method avoids introducing mid- or high- spatial frequency errors by eliminating contact between the glass and mandrel. Together, these two methods form a promising approach to fabricating mirrors for a high angular resolution, large-area x-ray observatory. In this paper we report on progress in understanding gas bearing slumping, and advancing the technology to curved geometry. We also report on continued progress on advancing the ion implantation technology toward correcting flight-sized mirror substrates.

Activation of phosphoinositide-specific phospholipase C (PLC) generates two intracellular signals which play major roles in many cellular processes including secretion, proliferation and contraction. PLC activation by many receptors occurs via a guanine nucleotide regulatory protein, Gp. PLCs are found predominantly in the cytosolic fraction though some activity is membrane-associated. At least four families of iso-enzymes of PLC (alpha, beta, gamma and delta) have been identified, but there is only scant evidence to indicate that any of the mammalian cytosolic activities are involved in G-protein-regulated signalling. In this study we demonstrate that the PLC activity from rat brain cytosol can be regulated in a G-protein-dependent manner in a reconstituted system using pre-permeabilized HL60 cells. We identify two enzymes, PLC-beta and a novel 86 kDa enzyme (designated PLC-epsilon) as the G-protein-regulated enzymes. PLC-epsilon was found to be the major G-protein-regulated enzyme.

Biotechnology and BioengineeringVolume 21, Issue 12 p. 2359-2363 Communications to the EditorFree Access Nonporous magnetic supports for proteases, cell-lytic enzymes, and ribonuclease: Limits of reactant size P. J. Halling, P. J. Halling Department of Chemical and Biochemical Engineering, University College London, Torrington Place, London, WC1E 7JE, EnglandSearch for more papers by this authorJ. A. Asenjo, J. A. Asenjo Department of Chemical and Biochemical Engineering, University College London, Torrington Place, London, WC1E 7JE, EnglandSearch for more papers by this authorP. Dunnill, P. Dunnill Department of Chemical and Biochemical Engineering, University College London, Torrington Place, London, WC1E 7JE, EnglandSearch for more papers by this author P. J. Halling, P. J. Halling Department of Chemical and Biochemical Engineering, University College London, Torrington Place, London, WC1E 7JE, EnglandSearch for more papers by this authorJ. A. Asenjo, J. A. Asenjo Department of Chemical and Biochemical Engineering, University College London, Torrington Place, London, WC1E 7JE, EnglandSearch for more papers by this authorP. Dunnill, P. Dunnill Department of Chemical and Biochemical Engineering, University College London, Torrington Place, London, WC1E 7JE, EnglandSearch for more papers by this author First published: December 1979 https://doi.org/10.1002/bit.260211217Citations: 14AboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onFacebookTwitterLinked InRedditWechat Citing Literature Volume21, Issue12December 1979Pages 2359-2363 ReferencesRelatedInformation

Clinical OtolaryngologyVolume 39, Issue 6 p. 328-333 Editorial Comment Getting involved in ENT clinical research in the UK; how can the NIHR Clinical Research Network help? H. Blackshaw, H. Blackshaw evidENT, Ear Institute, University College London, London, UKSearch for more papers by this authorC. Philpott, C. Philpott Norwich Medical School, University of East Anglia, Norwich, UKSearch for more papers by this authorM.F. Bhutta, M.F. Bhutta evidENT, Ear Institute, University College London, London, UKSearch for more papers by this authorS. Cooper, S. Cooper NIHR Clinical Research Network Coordinating Centre, Leeds, UKSearch for more papers by this authorA.G.M. Schilder, A.G.M. Schilder evidENT, Ear Institute, University College London, London, UKSearch for more papers by this author H. Blackshaw, H. Blackshaw evidENT, Ear Institute, University College London, London, UKSearch for more papers by this authorC. Philpott, C. Philpott Norwich Medical School, University of East Anglia, Norwich, UKSearch for more papers by this authorM.F. Bhutta, M.F. Bhutta evidENT, Ear Institute, University College London, London, UKSearch for more papers by this authorS. Cooper, S. Cooper NIHR Clinical Research Network Coordinating Centre, Leeds, UKSearch for more papers by this authorA.G.M. Schilder, A.G.M. Schilder evidENT, Ear Institute, University College London, London, UKSearch for more papers by this author First published: 23 November 2014 https://doi.org/10.1111/coa.12318Citations: 1Read the full textAboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Citing Literature Volume39, Issue6December 2014Pages 328-333 RelatedInformation

Equilibration of chloride and pyruvate distributions between liver mitochondria and medium mediated by organo-tin salts

Economic AffairsVolume 36, Issue 1 p. 91-101 Review Article Picking Up the Gauntlet: Richard Thaler's Defence of Behavioural Economics Paul Ormerod, Corresponding Author Paul Ormerod Volterra Partners LLP, London and University College London, London, United KingdomVolterra Partners LLP, London and University College London. Email: pormerod@volterra.co.ukSearch for more papers by this author Paul Ormerod, Corresponding Author Paul Ormerod Volterra Partners LLP, London and University College London, London, United KingdomVolterra Partners LLP, London and University College London. Email: pormerod@volterra.co.ukSearch for more papers by this author First published: 25 February 2016 https://doi.org/10.1111/ecaf.12159Citations: 2Read the full textAboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onFacebookTwitterLinked InRedditWechat Citing Literature Volume36, Issue1February 2016Pages 91-101 RelatedInformation

UCL (University College London) strongly supports the implementation of Open Science policies and practices. The library has taken the lead in the university across all eight areas of Open Science: the Future of Scholarly Communication, the EOSC, FAIR data, Skills, Research Integrity, Rewards, Altmetrics, and Citizen Science. UCL has modified these themes slightly to better fit its academic requirements, developing ambitious programmes and services to support the change of culture which is required. From the future of scholarly publishing, with the formation of UCL Press as the UK's first fully open access university press, to research data management, rewards, research integrity and next-generation metrics, UCL has become a leader in Open Science. This chapter analyses the success of UCL to date, describes the challenges, shows the benefits, and indicates what future steps are being planned to deliver a culture where Open Science is the default, thus delivering on the prophecy of Mahatma Ghandi, one of UCL's most illustrious alumni, ‘The future depends on what you do today'.

SIU Scholarship: Dr. Viacheslav Iremashvili

For more than 40 years in Marseille Provence observatories active optics concepts have found many fruitful developments in uv, visible and ir telescope optics. For these wavelength ranges, active optics methods are now widely extended by current use of variable curvature mirrors, in situ aspherization processes, stress figuring apsherization processes, replications of stressed diffraction gratings, and in situ control of large telescope optics. X-ray telescope mirrors will also benefit soon from the enhanced performances of active optics. For instance, the 0.5-1 arcsec spatial resolution of Chandra will be followed up by increased resolution space telescopes which will require the effective construction of more strictly aplanatic grazing-incidence two-mirror systems. In view to achieve a high-resolution imaging with two-mirror grazing-incidence telescope, say, 0.1 arcsec, this article briefly reviews the alternative optical concepts. Next, active optics analysis is investigated with the elasticity theory of shells for the active aspherization and in situ control of monolithic and segmented telescope mirrors for x-ray astronomy. An elasticity theory of weakly conical shells is developed for a first approach which uses a monotonic extension (or retraction) of the shell.

The Department of Geological Sciences at University College London (UCL), has undergone a period of major expansion and growth as a result of the restructuring of geology departments within the University of London that was carried out in 1982. This exercise produced the amalgamation of selected parts of the Department of Geological Sciences of Queen Mary College and the Department of Geology, UCL, on the UCL site. The creation of this strengthened grouping has been successful in attracting a significant number of active researchers in the field of rock and mineral physics (RMP) to the new UCL department. As a result, the academic staff has more than douhled since 1982 and now stands at 31.

Elizabeth Murray

Effect of combined lamivudine and interferon alpha treatment on the T-cell response to HBV core peptides in paediatric patients infected with chronic hepatitis B virus: M Cavers, Institute of Hepatology, University College London, London Uk; M Aw, L D'Antiga, Institute of Child Health, King's College London, London Uk; F Malacarne, R Williams, Institute of Hepatology, University College London, London Uk;