QUALITY OF LIFE OF PATIENTS TREATED BY VALVE-SPARING AORTIC ROOT REPLACEMENT

Aim. To assess the condition of hepatopancreatobiliary system and quality of life in patients in the remote period after cholecystectomy.Methods. 88 patients with cholelithiasis who undergone cholecystectomy in 2008-2010 were examined 5 years after the surgery. Common blood count, blood biochemistry test were performed, fasting blood glucose level was measured, esophagogastroduodenoscopy, ultrasonic examination of abdominal organs, fractional duodenal intubation, fecal elastase test (ELISA, «BioServ Diagnostics», Germany) were performed. Patients filled out questionnaires to assess the quality of life: MOS SF-36 (Medical Outcomes Study Short Form), GIQLI (Gastrointestinal Quality of Life Index) before, 1 and 5 years after cholecystectomy.Results. According to the esophagogastroduodenoscopy, 56 (63.6%) patients had duodenal reflux, 21 (23.8%) - duodenal diverticula, 9 (10.2%) - reflux esophagitis. Reduced fecal pancreatic elastase-1 was detected in 37 (42%) of patients. According to the fractional duodenal intubation, hypersecretory type was the most prevalent, 40 (45.5%) patients had hypotonic sphincter of Oddi, 48 (54.5%) - hypertonic sphincter of Oddi. All patients had crystals of calcium bilirubinate, leukocytes and bacteria in bile, microliths were identified in 76 (86%) of patients. After emergency surgery, quality of life increased by all indicators, after planned cholecystectomy for asymptomatic cholelithiasis the quality of life decreased 1 and 5 years after cholecystectomy. After planned cholecystectomy for symptomatic cholelithiasis, the surgery improved quality of life, but after 5 years indicators for quality of life returned to preoperative levels.Conclusion. Various changes in hepatopancreatobiliary system organs are detected in patients after cholecystectomy, like disorders of bile formation and biliary excretion, sphincter of Oddi dysfunction, decreased function of the pancreas, which reduce the quality of life.

0323: Mid-term follow-up and quality of life in patients after Fontan surgery

Qol-P-03 - Quality of life in patients with mycosis fungoides and Sézary syndrome: a review of the literature

The term aortic valve-sparing root replacement (AVSRR) surgery encompasses a variety of techniques. The David operation or aortic valve reimplantation procedure is the most commonly performed AVSRR. Other variants of AVSRR include the remodeling or Yacoub technique, as well as modifications of the Yacoub procedure combined with a variety of aortic annuloplasty techniques. Connective tissue disorders such as Marfan, Loeys-Dietz and Ehlers-Danlos syndromes are usual etiologies of aortic root aneurysms in young patients. The David operation can be performed in nearly all patients with aortic root aneurysms and pliable aortic valve cusps. It is particularly valuable in young patients and those with connective tissue disorders. Current guidelines recommend prophylactic aortic root/ascending aorta surgery in different scenarios in order to avoid aortic rupture or dissection. Outstanding short- and long-term survival as well as excellent freedom from reoperation have been demonstrated after the David operation. This chapter provides an overview of the indications, various techniques and outcomes of AVSRR surgery, with a particular focus on David operation.

This study aimed to evaluate quality of life, psychological morbidity, nicotine dependence and family coping in smokers and abstinents. 116 smokers and 117 abstinents, from both sexes, participated in the study. All participants answered the following instruments: Socio-Demographic; Medical Outcomes Study Short Form 36 (MOS SF-36); Depresion, Anxiety, Stress Scales (DASS); Fagerstrom Test for Nicotine Dependence (FTND) and Family Crises-Oriented Personal Evaluation Scales (F-COPES). According to the results, in smokers who also have a partner who smokes, high nicotine dependence and psychological morbidity predict less physical quality of life. High psychological morbidity and passive assessment, predict less quality of life. As for abstinents, having chronic respiratory disease, high psychological morbidity and looking for spiritual support predicted poorer quality of physical life. Being female, having chronic respiratory disease and psychological morbidity predicted lower mental quality of life. Hereafter, intervention programs should include partners as well as psychological morbidity and coping strategies in order to increase quality of life.

Aortic dissection is a severe and life-threatening disease that is usually linked with numerous possible complications. Stanford type B aortic dissection patients often choose endovascular repair due to its mini-invasiveness and quick recovery. This study concerns with medial-term outcome and quality of life (QoL) in patients with Stanford type B aortic dissection after endovascular repair. From January 2014 until July 2016, 40 patients with Stanford type B aortic dissection received an endovascular repair. Of the total number of patients, 35 were males (87.5%) and 5 females (12.5%), mean aged 80.9±14.1 years. The Medical Outcomes Study-Short Form-36 (MOS SF-36) was used to assess the QoL preoperatively and after endovascular repair. The first follow-up (FU) of SF-36 questionnaire (FU1) was obtained within 3.9±0.3 months after repair, and the second (FU2), 25.6±6.5 months thereafter. None of patient died during the observational period, and one patient lost to FU. SF-36 observation showed the best-scoring domain was 'Role emotion', 'Vitality' and 'Mental health' were also scored well preoperatively. Except for 'Role emotion' and 'Mental health', all remained domains were significantly improved both FU1 and FU2. Endovascular repair in patients with Stanford type B aortic dissection enables excellent clinical outcomes and QoL.

To examine the factors associated with the quality of life and the mediating effect of self-efficacy in the relationship between mental health and quality of life among patients with hypertensive nephrology. A cross-sectional and correlational study using the Strengthening the Reporting of Observational Studies in Epidemiology checklist guidelines. A total of 202 participants were collected from November 2019 to September 2020 from the outpatient department of nephrology of a regional teaching hospital in Taiwan using a convenience sampling method. The research tools included the World Health Organization-5 Well-Being Index, the Chronic Kidney Disease Self-Efficacy Instrument and the Medical Outcome Study Short Form-12. The mediating effect was statistically analysed by linear regression models and verified by Sobel testing. Mental health and self-efficacy were positively correlated with the overall quality of life. The results showed that the total explanatory variation of mental health and self-efficacy on the overall quality of life was 37.1%. Mental health was the most important explanatory factor, which could explain 27.1% of the variations in the overall quality of life alone. Moreover, self-efficacy was a partial mediator in the relationship between mental health and the quality of life among patients with hypertensive nephrology, with a total effect of 34.8%. The quality of life of this population can be improved by enhancing mental health, leading to an improvement in self-efficacy. Consequently, improved mental health and self-efficacy will improve the overall quality of life. Medical staff should be able to assess patients' mental health in providing referrals and assistance in a timely manner. If intervention programmes can be developed to improve patients' self-efficacy, their quality of life can also be improved.

Objective To assess the effect of a multimodal group exercise intervention, as an adjunct to conventional care, on fatigue, physical capacity, general wellbeing, physical activity, and quality of life in...

To assess 3 years of quality of life in patients with esophageal cancer in a randomized trial comparing limited transhiatal resection with extended transthoracic resection. Quality-of-life questionnaires were sent at baseline and at 5 weeks; 3, 6, 9, and 12 months; and 1.5, 2, 2.5, and 3 years after surgery. Physical and psychological symptoms, activity level, and global quality of life were assessed with the disease-specific Rotterdam Symptom Checklist. Generic quality of life was measured with the Medical Outcomes Study Short Form-20. A total of 199 patients participated. Physical symptoms and activity level declined after the operation and gradually returned toward baseline within the first year (P < .01). Psychological well-being consistently improved after baseline (P < .01), whereas global quality of life showed a small initial decline followed by continuous gradual improvement (P < .01). Quality of life stabilized in the second and third year. Three months after the operation, patients in the transhiatal esophagectomy group (n = 96) reported fewer physical symptoms (P = .01) and better activity levels (P < .01) than patients in the transthoracic group (n = 103), but no differences were found at any other measurement point. For psychological symptoms and global quality of life, no differences were found at any follow-up measurement. A similar pattern was found for generic quality of life. No lasting differences in quality of life of patients who underwent either transhiatal or transthoracic resection were found. Compared with baseline, quality of life declined after the operation but was restored within a year in both groups.

Valve-sparing root replacement after the Ross procedure

With improved overall survival of cervical cancer patients, the importance of the quality of life (QOL) is increasingly recognized. This study was conducted to compare the QOL of women with different stage cervical cancer before and after treatment to facilitate improved cervical cancer prevention and treatment. We used the generic Medical Outcomes Study Short Form-36 (MOS SF-36) to collect QOL information. Based on SF-36, we interviewed cervical cancer patients at West China Second Affiliated Hospital and Sichuan Cancer Hospital between May 2010 and January 2011. A total of 92 patients with precancerous lesions, 93 with early cancer, and 35 with advanced cancer responded to our survey. Average physical component summary (PCS) scores were significantly different between the three groups at every time point (P < 0.05). Average mental component summary (MCS) scores were significantly different between the three groups after treatment (P < 0.05). Average PCS and MCS scores increased gradually from the pretreatment to posttreatment period for patients with precancerous lesions. However, they reached the lowest at 1 month after treatment for patients with early and advanced cancers and rebounded between 1 and 6 months after treatment. Our results indicate that patients with precancerous lesions and early cervical cancer show better overall QOL than do those with advanced cervical cancer. Additionally, patients with early cancer recover more quickly than do those with advanced cancer in terms of both physical and mental functions. Thus, early detection and treatment initiatives may improve the QOL for patients with precancerous lesions and cervical cancer.

Quality of life (QL) is an indicator widely used worldwide to assess the physical, mental and social state of a person’s health, which is especially important for the expectant mother. During pregnancy, the most widely discussed area of QL is physical health. However, this does not diminish the important role of the psychological state and social relationships in pregnant womenThe objective: to study the QL and psycho-emotional state in pregnant women with urerine hyperproliferative diseases (HPD).Materials and methods. By means of a questionnaire during 2018–2024, 680 pregnant women with uterine HPD were examined. They were observed and delivered in the Department of purulent-inflammatory diseases in obstetrics and were undergoing treatment and examination in the Department of rehabilitation of women’s reproductive function or in the women’s consultation of the SI “Ukrainian Center of Maternity and Childhood of the National Academy of Medical Sciences of Ukraine”. The main group (MG) included 517 pregnant women with a combinated forms of HPD, which included: uterine endometriosis (adenomyosis), uterine leiomyoma (UL), endometrial polyps and/or glandular endometrial hyperplasia which were diagnosed before pregnancy. 82 pregnant women without uterine HPD (absent of adenomyosis, UL, endometrial polyps and/or glandular endometrial hyperplasia before pregnancy) included into the comparison group (CpmG). 81 pregnant women without uterine HPD (absent of adenomyosis, UL, endometrial polyps and/or glandular endometrial hyperplasia before pregnancy) and without pregnancy complications were included into the control group (CtrlG). The study is prospective, cohort randomized. Psychometric research methods were used, in particular, assessment of health-related QL by MOS SF-36 (Medical Outcomes Study Short Form) and the QL assessment scale (O. S. Chaban) and psychosomatic disorders using the Hospital Anxiety and Depression Scale (HADS).Results. QL indicators in pregnant women with uterine HPD significantly differed from those in healthy women and pregnant women without uterine HPD, which indicates negative changes in both physical health and mental health, especially due to such QL parameters as role-emotional functioning and vital activity. After 2022, 82% of pregnant women in the MG answered the question “Were you very nervous?” – “Most of the time” (until 2022 – 39%), and 76% of patients answered the question “Did you feel down or depressed?” – “All the time” (until 2022 – 27%). A low level of QL was found in 14% of pregnant women with uterine HPD, which indicates dissatisfaction with their lives, the presence of significant problems and those that are difficult to solve, and the lack of joy from life, which is perceived as a difficult struggle with an uncertain and mostly negative future. This indicator is 2.3 times higher than the similar one in the CtrlG (p &lt; 0.05) and by 3% in the CpmG.Conclusions. In pregnant women with uterine HPD (UL, adenomyosis, endometrial polyps and/or endometrial hyperplasia), such indicators of QL as psychological health (according to the SF-36 scale), role-emotional functioning and vital activity are especially reduced.

P0166 Presence of stoma nurse and quality of life of colorectal cancer patients with fecal ostomy in the early postoperative phase

We assessed the impact of surgical treatment of Parkinson's disease on quality of life using generic quality of life instruments and utility scores. The Medical Outcomes Study short form health survey SF-36 and Parkinson's Disease Questionnaire PDQ-39 were used before and 3-6 months after surgery to assess quality of life, and the results were converted into utility valuations. Ninety-seven patients were studied; 33 underwent unilateral thalamotomy, 33 unilateral pallidotomy, 20 bilateral pallidotomy, six subthalamic nucleus (STN) lesions, four mixed lesions, and in one case bilateral STN stimulation. All dimensions of the SF-36 except role mental and mental health showed statistically significant improvement following surgery. The PDQ-39 recorded significant improvements in the mobility, stigma, and bodily discomfort dimensions. The rating scale and time trade-off scales showed statistically significant gains in utility of 8% and 3%, respectively. Gains were particularly marked in the bilateral pallidotomy group. Differences in patient characteristics and selection made direct comparisons between procedures unreliable. Quality of life in patients with advanced Parkinson's disease is amenable to measurement; such measurement provides tentative evidence of significant gains in quality of life following some neurosurgical procedures.

Background. In conditions of permanent progress in the quality of surgical care in various areas of surgery, it is very important to allow patients themselves to evaluate provided treatment.&#x0D; Aims: this paper analyzes the quality of life in individuals with acute lower limb ischemia who have undergone lower limb revascularization surgery.&#x0D; Materials and methods. An assessment of the quality of life of 122 patients with acute lower limb ischemia (ALI) of II degree who were treated at the Moscow Сity Сlinical Hospital оf S.S. Yudin from 2016 to 2018 (average age 72.1 14.7 years) was performed. The quality of life was assessed using the medical Outcomes Study-Short Form (MOS SF-36) quality of life assessment methodology.&#x0D; Results. When assessing the quality of life of patients, it was found that the psychological and physical components of patients health are significantly affected by the angiotropic effect of the affecting factor associated with the presence of diabetes mellitus. 1 month after surgical restoration of blood flow against the background of the initial embolism, 83.6% of the respondents who did not suffer from diabetes noted a persistent improvement in their General condition and quality of life.&#x0D; Conclusion. This method of assessing the quality of life after surgical restoration of blood flow in patients with acute lower limb ischemia can be used in angiosurgical practice and clearly reflects of patient satisfaction with the treatment.