Raffaele Mezzenga.

"My biggest motivation is to make a creative and significant contribution in several research fields … My favorite saying is to try our best without regret " Find out more about Bin Tan in his Author Profile.

Joseph S. Francisco

Angewandte Chemie International EditionVolume 56, Issue 3 p. 678-678 Author ProfileFree Access Andreas Gansäuer First published: 31 August 2016 https://doi.org/10.1002/anie.201607115AboutSectionsPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onFacebookTwitterLinkedInRedditWechat Graphical Abstract “My favorite musician is Bruce Springsteen. My motto is ‘perfectionism is paralysis’ ...” This and more about Andreas Gansäuer can be found on page 678. Andreas Gansäuer The author presented on this page has published more than 10 articles in Angewandte Chemie in the last 10 years, most recently: “Synthesis of Dihydropyrrolizine and Tetrahydroindolizine Scaffolds from Pyrroles by Titanocene(III) Catalysis”: S. Hildebrandt, A. Gansäuer, Angew. Chem. Int. Ed. 2016, 55, 9719; Angew. Chem. 2016, 128, 9871. The work of A. Gansäuer has been featured on the cover of Angewandte Chemie: “Amide-Substituted Titanocenes in Hydrogen-Atom Transfer Catalysis”: Y.-Q. Zhang, V. Jakoby, K. Stainer, A. Schmer, S. Klare, M. Bauer, S. Grimme, J. M. Cuerva, A. Gansäuer, Angew. Chem. Int. Ed. 2016, 55, 1523; Angew. Chem. 2016, 128, 1546. Date of birth: October 3, 1966 Position: Professor, University of Bonn E-mail: andreas.gansaeuer@uni-bonn.de Homepage https://www.chemie.uni-bonn.de/oc/forschung/arbeitsgruppen/ak_ga/willkommen Education: 1992 Degree in chemistry, University of Bonn and Oxford University 1994 PhD with Manfred T. Reetz, Max Planck Institute for Coal Research, Mülheim an der Ruhr 1995 Postdoctoral work with Barry M. Trost, Stanford University 1996–2000 Habilitation mentored by Reinhard Brückner, University of Göttingen Research: Catalysis, electron transfer, radicals, sustainability Hobbies: Chess, reading, travelling My favorite musician is Bruce Springsteen. My motto is “perfectionism is paralysis”. Young people should study chemistry because it's a great challenge, it can be done everywhere in the world, and, yes, it is fun. Last time I went to the pub was with my wife. We had Schnitzel and beer, and watched football. My favorite drink is Eifeler Landbier, naturally, and helles Hefeweizen (pale wheat beer)! In a spare hour, I fall asleep. My favorite time of day is sunset. I get advice from my teenage daughters. Fortunately, they are never afraid of saying what they think and want. I advise my students to work and think for themselves and not for me. If I had one year of paid leave I would leave and travel to the Faroe Islands, the Cook Islands, and to Rio del Mar Beach, California. The most important thing I learned from my students is to take a fresh look at things. My favorite books are Snow Falling on Cedars (David Guterson) and Touch (Alexi Zentner). When I was eighteen I wanted to be eighteen. If I could be described as an animal it would be our cat Lucy. Up all night, sleeping all day, and still well-looked-after. My 5 top papers: References 1“The Emergence of a Novel Catalytic Radical Reaction: Titanocene Catalyzed Reductive Opening of Epoxides ”: A. Gansäuer, H. Bluhm, M. Pierobon, J. Am. Chem. Soc. 1998, 120, 12849. (The idea for my first grant proposal was good, we were on the right track!) 2“A Catalytic Enantioselective Electron Transfer Reaction: Titanocene-Catalyzed Enantioselective Formation of Radicals from meso-Epoxides”: A. Gansäuer, T. Lauterbach, H. Bluhm, M. Noltemeyer, Angew. Chem. Int. Ed. 1999, 38, 2909; Angew. Chem. 1999, 111, 3112. (We found the right complex for enantioselective catalysis and with it, I got a job.) 3“The Mechanism of Titanocene-Mediated Epoxide Opening Through Homolytic Substitution”: A. Gansäuer, A. Barchuk, F. Keller, M. Schmitt, S. Grimme, M. Gerenkamp, C. Mück-Lichtenfeld, K. Daasbjerg, H. Svith, J. Am. Chem. Soc. 2007, 129, 1359. (I realized how important it is to have great cooperation partners for tackling difficult problems.) 4“Catalytic Enantioselective Radical Cyclization via Regiodivergent Epoxide Opening” A. Gansäuer, L. Shi, M. Otte, J. Am. Chem. Soc. 2010, 132, 11858. (We were able to use our mechanistic insights for designing this reaction.) 5“Catalytic, Atom-Economical Radical Arylation of Epoxides”: A. Gansäuer, M. Behlendorf, D. von Laufenberg, A. Fleckhaus, C. Kube, D. V. Sadasivam, R. A. Flowers II, Angew. Chem. Int. Ed. 2012, 51, 4739; Angew. Chem. 2012, 124, 4819. (Synthesis, kinetics, and theory enabled us to understand an intriguing reaction and to devise a highly active catalyst.) Volume56, Issue3January 16, 2017Pages 678-678 ReferencesRelatedInformation

"In a spare hour, I walk my dog … My favorite time of day is when I enjoy my walks in the garden…" Find out more about Xiaohua Liu in her Author Profile.

Protein folding involves a large number of steps and conformations in which the folding protein samples different thermodynamic states characterized by local minima. Kinetically trapped on- or off-pathway intermediates are metastable folding intermediates towards the lowest absolute energy minima, which have been postulated to be the natively folded state where intramolecular interactions dominate, and the amyloid state where intermolecular interactions dominate. However, this view largely neglects the rich polymorphism found within amyloid species. We review the protein folding energy landscape in view of recent findings identifying specific transition routes among different amyloid polymorphs. Observed transitions such as twisted ribbon→crystal or helical ribbon→nanotube, and forbidden transitions such helical ribbon↛crystal, are discussed and positioned within the protein folding and aggregation energy landscape. Finally, amyloid crystals are identified as the ground state of the protein folding and aggregation energy landscape.

Angewandte Chemie International EditionVolume 57, Issue 14 p. 3544-3544 Author ProfileFree Access Nediljko (Ned) Budisa First published: 30 November 2017 https://doi.org/10.1002/anie.201711475AboutSectionsPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onFacebookTwitterLinkedInRedditWechat Graphical Abstract “My science heroes are Oswald T. Avery, Erwin Chargaff, and Edward O. Wilson. If I had one year of paid leave I would follow the path of St. Paul's missionary journeys ...” This and more about Nediljko (Ned) Budisa can be found on page 3544. Nediljko (Ned) Budisa The author presented on this page has recently published his 10th article in Angewandte Chemie in the last 10 years: “Biocatalysis with Unnatural Amino Acids: Enzymology Meets Xenobiology”: F. Agostini, J.-S. Völler, B. Koksch, C. G. Acevedo-Rocha, V. Kubyshkin, N. Budisa, Angew. Chem. Int. Ed. 2017, 56, 9680; Angew. Chem. 2017, 129, 9810. The work of N. Budisa has been featured on the inside cover of Angewandte Chemie: “Chemical Evolution of a Bacterial Proteome”: M. G. Hoesl et al., Angew. Chem. Int. Ed. 2015, 54, 10030; Angew. Chem. 2015, 127, 10168. Date of birth: November 21, 1966 Position: Professor of Biocatalysis, Technische Universität Berlin E-mail: budisa@chem.tu-berlin.de Homepage: www.biocat.tu-berlin.de ORCID: 0000-0001-8437-7304 Education: 1993 MSc (molecular biology and molecular biophysics), Zagreb University 1997 PhD supervised by Robert Huber, Max Planck Institute (MPI) of Biochemistry, Martinsried, and Technische Universität München (TUM) 2001–2005 Habilitation in biochemistry, MPI of Biochemistry and TUM Awards: 2004 BioFuture Award Research: Biochemistry, biophysics, genetic-code engineering, synthetic biology, xenobiology Hobbies: Boxing, history, onomastics, philosophy, religion My science heroes are Oswald T. Avery, Erwin Chargaff, and Edward O. Wilson. If I had one year of paid leave I would follow the path of St. Paul's missionary journeys. The principal aspect of my personality is a noble character mixed with stubbornness. My favorite scientific author is Charles Darwin. My favorite painter is Jean-François Millet. My favorite book is The Idiot by Fyodor M. Dostoyevsky. The natural talent I would like to be gifted with is to run faster than Usain Bolt and to punch better than Muhammad Ali. The greatest scientific advance of the last decade was the emergence of xenobiology. Young people should study chemistry because biology is too important to be left to biologists only. The most significant scientific event of the past 100 years was the discovery of DNA as the hereditary material. I admire principled, reliable, and modest people. I advise my students to listen to Sting: “it takes a man to suffer ignorance and smile; be yourself no matter what they say”. My favorite way to spend a holiday is to visit the places that have witnessed many historical events with a great global impact. My 5 top papers: 1“In Vivo Double and Triple Labeling of Proteins Using Synthetic Amino Acids”: S. Lepthien, L. Merkel, N Budisa, Angew. Chem. Int. Ed. 2010, 49, 5446; Angew. Chem. 2010, 122, 5576. (In vivo simultaneous incorporation of three chemically distinct noncanonical amino acids.) 2“Design of anti- and pro-aggregation variants to assess the effects of methionine oxidation in human prion protein”: C. Wolschner, A. Giese, H. Kretzschmar, R. Huber, L. Moroder, N. Budisa, Proc. Natl. Acad. Sci. USA 2009, 106, 7756. (Discovery and engineering of a chemical model for understanding of the role of methionine oxidation in prion protein aggregation.) 3“Synthetic Biology of Proteins: Tuning GFPs Folding and Stability with Fluoroproline”: T. Steiner, P. Hess, J. H. Bae, B. Wiltschi, L. Moroder, N. Budisa, PLoSONE 2008, 3, e 1680. (The roles of proline side-chain conformations in translation, folding and stability of proteins.) 4“Expansion of the Genetic Code Enables Design of a Novel ”Gold“ Class of Green Fluorescent Proteins”: J. H. Bae et al., J. Mol. Biol. 2003, 328, 1071. (Discovery and engineering of “gold” fluorescence and establishment of green-fluorescent protein as a model for expanded genetic-code studies.) 5“Residue-specific bioincorporation of non-natural biologically active amino acids into proteins as possible drug carriers: Structure and stability of the per-thiaproline mutant of annexin V”: N. Budisa, C. Minks, F. J. Medrano, J. Lutz, R. Huber, L. Moroder, Proc. Natl. Acad. Sci. USA 1998, 95, 455. (Discovery and establishment of the therapeutic potential of proteins with noncanonical amino acids.) Volume57, Issue14March 26, 2018Pages 3544-3544 ReferencesRelatedInformation

"The secret of being a successful scientist is to contribute results that benefit humanity. My biggest inspiration is to develop an idea which can come true …" Find out more about Ru-Shi Liu in his Author Profile.

Angewandte Chemie International EditionVolume 58, Issue 11 p. 3262-3262 Author ProfileFree Access Bing-Feng Shi First published: 18 October 2018 https://doi.org/10.1002/anie.201811536AboutSectionsPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onFacebookTwitterLinkedInRedditWechat Graphical Abstract “My favorite place on earth is where my family is. If I were not a scientist, I would be an architect …” Find out more about Bing-Feng Shi in his Author Profile. Bing-Feng Shi The author presented on this page has recently published his 10th article in Angewandte Chemie in the last 10 years: “Palladium(II)-Catalyzed Enantioselective Arylation of Unbiased Methylene C(sp3)−H Bonds Enabled by a 2-Pyridinylisopropyl Auxiliary and Chiral Phosphoric Acids”: S.-Y. Yan, Y.-Q. Han, Q.-J. Yao, X.-L. Nie, L. Liu, B.-F. Shi, Angew. Chem. Int. Ed. 2018, 57, 9093; Angew. Chem. 2018, 130, 9231. Work by B.-F. Shi has been featured on the cover of Angewandte Chemie: “PdII-Catalyzed Enantioselective Activation of C(sp2)−H and C(sp3)−H Bonds Using Monoprotected Amino Acids as Chiral Ligands”: B.-F. Shi, N. Maugel, Y.-H. Zhang, J.-Q. Yu, Angew. Chem. Int. Ed. 2008, 47, 4882; Angew. Chem. 2008, 120, 4960. Date of birth: July 8, 1978 Position: Professor, Department of Chemistry, Zhejiang University E-mail: bfshi@zju.edu.cn Homepage: http://mypage.zju.edu.cn/en/bfshi ORCID: 0000-0003-0375-955X Education: 2001 BS with Prof. Ji-Ben Meng, Nankai University, Tianjin 2006 PhD with Prof. Biao Yu, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences 2006–2007 Postdoc with Prof. Michael S. VanNieuwenhze, University of California, San Diego 2007–2010 Postdoc with Prof. Jin-Quan Yu, The Scripps Research Institute, San Diego Awards: 2014 Recipient, National Science Fund for Excellent Young Scholars; 2015 Distinguished Lectureship Award, Chemical Society of Japan; 2017 Changjiang Scholars Program, Ministry of Education of the People's Republic of China; 2018 Top-Notch Young Talents Program, Zhejiang Province Current research interests: Transition-metal-catalyzed selective activation of inert bonds; asymmetric synthesis; total synthesis; sustainable chemistry Hobbies: Reading, hiking, drinking, traveling My favorite place on earth is where my family is. If I were not a scientist, I would be an architect. I chose chemistry as a career because “Chemistry is like a box of chocolates. You never know what you're gonna get” (adapted from Forrest Gump!). My most exciting discovery to date has been the identification of monoprotected α-amino acids as privileged chiral ligands for Pd(II)-catalyzed enantioselective C−H activation. I lose track of time when I play with my children. The best advice I have ever been given is “You will never know your potential if you don't work hard”. The worst advice I have ever been given was “This won't work since lots of people have attempted it and not succeeded”. Be passionate and never give up. My top three films (or film series) of all time are Forrest Gump, A Chinese Odyssey (大话西游), Harry Potter. The downside of my job is that I don't have enough time to spend with my family. My favorite food is hot pot. My 5 top papers: 1“PdII-Catalyzed Enantioselective Activation of C(sp2)−H and C(sp3)−H Bonds Using Monoprotected Amino Acids as Chiral Ligands”: B.-F. Shi, N. Maugel, Y.-H. Zhang, J.-Q. Yu, Angew. Chem. Int. Ed. 2008, 47, 4882; Angew. Chem. 2008, 120, 4960. (My first work on C−H activation.) 2“Stereoselective Synthesis of Chiral α-Amino-β-Lactams through Palladium(II)-Catalyzed Sequential Monoarylation/Amidation of C(sp3)−H Bonds”: Q. Zhang, K. Chen, W. Rao, Y. Zhang, F.-J. Chen, B.-F. Shi, Angew. Chem. Int. Ed. 2013, 52, 13588; Angew. Chem. 2013, 125, 13833. (A 2-pyridinylisopropyl (PIP) directing group was developed for the efficient activation of methylene C(sp3)−H bonds.) 3“Stereoselective Synthesis of Chiral β-Fluoro α-Amino Acids via Pd(II)-Catalyzed Fluorination of Unactivated Methylene C(sp3)−H Bonds: Scope and Mechanistic Studies”: Q. Zhang, X.-S. Yin, K. Chen, S.-Q. Zhang, B.-F. Shi, J. Am. Chem. Soc. 2015, 137, 8219. (A PIP directing group enabled the stereoselective fluorination of unactivated methylene C(sp3)−H bonds.) 4“Site-Selective Alkenylation of δ-C(sp3)−H Bonds with Alkynes via a Six-Membered Palladacycle”: J.-W. Xu, Z.-Z. Zhang, W.-H. Rao, B.-F. Shi, J. Am. Chem. Soc. 2016, 138, 10750. (An unprecedented alkenylation reaction takes place in the presence of more accessible γ-C(sp3)−H bonds.) 5“Atroposelective Synthesis of Axially Chiral Biaryls by Pd-Catalyzed Asymmetric C−H Olefination Enabled by a Transient Chiral Auxiliary”: Q.-J. Yao, S. Zhang, B.-B. Zhan, B.-F. Shi, Angew. Chem. Int. Ed. 2017, 56, 6617; Angew. Chem. 2017, 129, 6717. (Efficient synthesis of enantioenriched biaryls by atroposelective C−H olefination using tert-leucine as a chiral auxiliary.) Volume58, Issue11March 11, 2019Pages 3262-3262 ReferencesRelatedInformation

Angewandte Chemie International EditionVolume 58, Issue 30 p. 10040-10040 Author ProfileFree Access Ryo Yoshida First published: 14 February 2019 https://doi.org/10.1002/anie.201901583AboutSectionsPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onFacebookTwitterLinkedInRedditWechat Graphical Abstract “The most important future application of my research is artificial life. The secret of being a successful scientist is having a sense of beauty …” Find out more about Ryo Yoshida in his Author Profile. Ryo Yoshida The author presented on this page has published his 10. article in Angewandte Chemie in the last 10 years: “Chemomechanical Motion of a Self-Oscillating Gel in a Protic Ionic Liquid”: T. Masuda, T. Ueki, R. Tamate, K. Matsukawa, R. Yoshida, Angew. Chem. Int. Ed. 2018, 57, 16693; Angew. Chem. 2018, 130, 16935. The work of R. Yoshida has been featured on the cover of Angewandte Chemie: “Evolved Colloidosomes Undergoing Cell-like Autonomous Shape Oscillations with Buckling”: R. Tamate, T. Ueki, R. Yoshida, Angew. Chem. Int. Ed. 2016, 55, 5179; Angew. Chem. 2016, 128, 5265. Date of birth: December 22, 1964 Position: Professor, School of Engineering, The University of Tokyo E-mail: ryo@cross.t.u-tokyo.ac.jp Homepage: http://cross.t.u-tokyo.ac.jp ORCID: 0000-0002-0558-2922 Education: 1988 BS, Waseda University, Tokyo, Japan 1993 PhD supervised by Kiyotaka Sakai, Waseda University, Tokyo, Japan (collaborative study supervised by Prof. Teruo Okano, Tokyo Women's Medical University, Tokyo, Japan) Awards: 2009 SPSJ Wiley Award, Society of Polymer Science Japan (SPSJ); 2018 New Age Technology Award, International Association of Advanced Materials Research: Design of functional polymer gels with spatio-temporal structure and development to biomimetic smart soft materials Hobbies: Playing classical and acoustic guitars The most important future application of my research is artificial life. The secret of being a successful scientist is having a sense of beauty. I get advice from Zen words. I admire laws and scenario of nature, life, and cosmos. My motto is Have originality. “Do not go where the path may lead, go instead where there is no path and leave a trail” (Ralph Waldo Emerson). Looking back over my career, I feel destiny. My favorite saying is “Let it be”. My biggest inspiration is designing a self-oscillating gel. My favorite way to spend a holiday is playing classical and acoustic guitars. My favorite name reaction is the Belousov–Zhabotinsky reaction. My science “heroes” are Albert Einstein, Erwin Schrödinger, Ilya Prigogine, Paul J. Flory, and others. The most important thing I learned from my students is the flow of time. The principal aspect of my personality is thoughtfulness. My favorite author is Steve Jobs as a creator and his way of thinking. My favorite composers and musicians are Johann Sebastian Bach, Andrés Segovia, Bon Jovi, X JAPAN, Billy Joel, Simon & Garfunkel, The Beatles, and others. My 5 top papers: 1“Comb-Type grafted Hydrogels with Rapid De-Swelling Response to Temperature Changes”: R. Yoshida, K. Uchida, Y. Kaneko, K. Sakai, A. Kikuchi, Y. Sakurai, T. Okano, Nature 1995, 374, 240. (This polymer network design to improve gel kinetics had a high impact on gel research.) 2“Self-Oscillating Gel”: R. Yoshida, T. Takahashi, T. Yamaguchi, H. Ichijo, J. Am. Chem. Soc. 1996, 118, 5134. (My first report of a novel polymer gel which autonomously swells and de-swells periodically in a closed homogeneous solution without any external stimuli—like heartbeat.) 3“Self-Walking Gel”: S. Maeda, Y. Hara, T. Sakai, R. Yoshida, S. Hashimoto, Adv. Mater. 2007, 19, 3480. (Application of the self-oscillating gel as an autonomous soft robot.) 4“Self-Beating Artificial Cells: Design of Cross-Linked Polmyersomes Showing Self-Oscillating Motion”: R. Tamate, T. Ueki, R. Yoshida, Adv. Mater. 2015, 27, 837. (One of a series of attempts to create artificial self-beating cells using the self-oscillating polymer, which would be a significant step in closing the gap between artificial and living cells.) 5“Amoeba-Like Self-Oscillating Polymeric Fluids with Autonomous Sol-Gel Transition”: M. Onoda, T. Ueki, R. Tamate, M. Shibayama, R. Yoshida, Nature Communications 2017, 15862. (A block copolymer solution that undergoes autonomous and periodic sol–gel transition under constant conditions, demonstrating strong potential to realize a type of bioinspired autonomous soft robots.) Volume58, Issue30July 22, 2019Pages 10040-10040 ReferencesRelatedInformation

Angewandte Chemie International EditionVolume 57, Issue 20 p. 5586-5586 Author ProfileFree Access Martin D. Smith First published: 13 December 2017 https://doi.org/10.1002/anie.201712087AboutSectionsPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onFacebookTwitterLinkedInRedditWechat Graphical Abstract “The secret of being a successful scientist is attracting the best students, curiosity, and good luck. My favorite name principle is the Woodward–Hoffmann rules ...” This and more about Martin D. Smith can be found on page 5586. Martin D. Smith The author presented on this page has published more than 10 articles in Angewandte Chemie in the last 10 years, most recently: “Discovery of a Highly Selective Cell-Active Inhibitor of the Histone Lysine Demethylases KDM2/7”: P. A. Gerken et al., Angew. Chem. Int. Ed. 2017, 56, 15555; Angew. Chem. 2017, 129, 15761. Date of birth: May 9, 1973 Position: Professor of Organic Chemistry and Director, EPSRC Centre for Doctoral Training in Synthesis for Biology and Medicine, University of Oxford E-mail: martin.smith@chem.ox.ac.uk Homepage: http://msmith.chem.ox.ac.uk; http://www.oxfordsynthesiscdt.ox.ac.uk ORCID: 0000-0002-8849-488X Education: 1995 BA, University of Oxford 1999 DPhil supervised by Prof. George W. J. Fleet, University of Oxford 2000–2003 Draper's Company Research Fellowship supervised by Prof. Steven V. Ley, University of Cambridge Current research interests: Enantioselective catalysis, synthesis, noncovalent interactions, mechanisms, phase-transfer catalysis Hobbies: Food and drink, gardening, literature The secret of being a successful scientist is attracting the best students, curiosity, and good luck. My favorite name principle is the Woodward–Hoffmann rules. My science “heroes” are Captain James Cook, R. B. Woodward, and Nikola Tesla. In the future, I see myself with an increasing amount of grey hair. The most important thing I learned from my students is that many of them are smarter than me. When I was eighteen I wanted to be good-looking. Or an astronaut. Young people should study chemistry because “power, wealth and prestige can only be obtained by the correct application of science” (D. H. R. Barton). Looking back over my career, I have been lucky to work with great mentors and great students. My favorite drink is champagne (but I'm not that fussy). My first experiment was trying to breathe underwater at about age 4 (it didn't work). In a spare hour, I play with my young son. I get advice from my colleagues in Oxford. They're a great bunch. I advise my students to not waste time drinking cheap wine. My favorite way to spend a holiday is with family, on the beach or in the mountains. My 5 top papers: 1“Catalytic enantioselective synthesis of indanes by a cation-directed 5-endo-trig reaction”: C. P. Johnston, A. Kothari, T. Sergeieva, S. I. Okovytyy, K. E. Jackson, R. S. Paton, M. D. Smith, Nature Chem. 2015, 7, 171. (Geometric and stereoelectronic effects are not always decisive in kinetically controlled ring-closing reactions.) 2“Can a C−H⋅⋅⋅O Interaction be a Determinant of Conformation?”: C. R. Jones, P. K. Baruah, A. L. Thompson, S. Scheiner, M. D. Smith, J. Am. Chem. Soc. 2012, 134, 12064. (We probed the role of relatively weak interactions through the competitive interplay of two noncovalent interactions.) 3“A Cascade Strategy Enables a Total Synthesis of (±)-Morphine”: S. Chu, N. Munster, T. Balan, M. D. Smith, Angew. Chem. Int. Ed. 2016, 55, 14306; Angew. Chem. 2016, 128, 14518. (This concise synthesis introduced us to photochemistry, an area we had no experience in at the time.) 4“Plagiarizing Proteins: Enhancing Efficiency in Asymmetric Hydrogen-Bonding Catalysis through Positive Cooperativity”: C. R. Jones, G. D. Pantoş, A. J. Morrison, M. D. Smith, Angew. Chem. Int. Ed. 2009, 48, 7391; Angew. Chem. 2009, 121, 7527. (Hydrogen-bonded foldamers can be both catalytically proficient and highly enantioselective at very low loadings.) 5“Catalytic enantioselective synthesis of atropisomeric biaryls by a cation-directed O-alkylation”: J. D. Jolliffe, R. J. Armstrong, M. D. Smith, Nature Chem. 2017, 9, 558. (A chiral counterion can mediate a dynamic kinetic resolution of atropisomeric enolates.) Volume57, Issue20May 14, 2018Pages 5586-5586 ReferencesRelatedInformation

The most exciting thing about my research is that it helps others understand their results and guides them to propose further research directions.I would have liked to have discovered the Fourth Law of Thermodynamics.The worst advice Ihave ever been given was to drop Physics in high school, which Ii gnored.Mytop three films of all time are Willow, Ladyhawke,and Jurassic Park.The downside of my job is that work is never finished.Myfavorite food is Sushi.Myfavorite song is "Keep on rocking in the free world" (Neil Young).Myfavorite motto is "Dontworry,beh appy".The most significant scientific advance of the last 100 years has been computer technology.The biggest problem that scientists face is being bullied by politicians and policy makers rather than thinking creatively and doing blue sky research.What Il ook for first in apublication is exciting and novel ideas and creative solutions.Myb est investment was as olar-powered calculator Ib ought for my Master studies,w hich still works and never needed batteries.

Beauty vs. Horror in

chocolate) or MannersN eapolitan Wafers.Myfavorite food is pierogi (Polish dumplings), with some fried onions and smetana (sour cream).

"The best advice I have ever been given is in two parts: 1) while it is important in life to learn how to connect dots, you have to collect dots first, and 2) don't forget to give yourself time to think …" Find out more about Darren Johnson in his Author Profile.

Journal AWWAVolume 21, Issue 11 p. 1525-1530 Article The Ohio Conference on Water Purification† F. H. Waking, F. H. WakingChief Engineer, State Department of Health, Columbus, Ohio.Search for more papers by this author F. H. Waking, F. H. WakingChief Engineer, State Department of Health, Columbus, Ohio.Search for more papers by this author First published: 01 November 1929 https://doi.org/10.1002/j.1551-8833.1929.tb17021.x †Presented before the Central States Section meeting, August 24, 1928. AboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onFacebookTwitterLinkedInRedditWechat Volume21, Issue11November 1929Pages 1525-1530 RelatedInformation