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  • https://doi.org/10.1117/12.2600179Copy DOI Icon

Reconstruction of compressed sensing Raman imaging using machine learning

  • Sep 12, 2021
  • Markus Nordberg +3 more
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Abstract

Raman spectroscopy is an efficient method for detection of explosives even in small quantities. A laser can be combined with a Coded Aperture Snapshot Spectral Imaging (CASSI) system to collect Raman spectra from a surface at stand-off distances. The CASSI-system decrease the data collection time but instead increase the reconstruction time for the Raman image. Reconstruction of Raman spectra from an ensemble of compressed sensing measurements using standard reconstruction methods such as Total Variation (TV) is rather time consuming and limits the application domain for the technique. Novel machine learning approaches such as Deep Learning (DL) has lately been applied to reconstruction problems. We evaluate our earlier developed DL approach for reconstruction of Raman spectra from an ensemble of measurements formulated as a regression problem. The DL network is trained by minimizing a loss-function which is composed of two components: a reconstruction error and a re-projection error. The evaluated method is trained on simulated data where the training data has been generated using a transfer function. The transfer function has been developed to mimic the optical properties of a CASSI system. The DL network has been trained on different training sets with different levels of background noise, different number of materials in the scene and different spatial configurations of the materials in the scene. The reconstruction results using the DL network has been qualitatively evaluated on simulated data and the results are also compared to the Two-Step Iterative Shrinkage/Thresholding (TwIST) algorithm in terms of reconstruction quality and computation time. The reconstruction time for the DL are orders of magnitude lower than for TwIST without reducing the quality of the reconstructed Raman spectra.

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