Restricted EM algorithm with application to probit models

For a balanced two‐way mixed model, the maximum likelihood (ML) and restricted ML (REML) estimators of the variance components were obtained and compared under the non‐negativity requirements of the variance components by Lee and Kapadia (1984). In this note, for a mixed (random blocks) incomplete block model, explicit forms for the REML estimators of variance components are obtained. They are always non‐negative and have smaller mean squared error (MSE) than the analysis of variance (AOV) estimators. The asymptotic sampling variances of the maximum likelihood (ML) estimators and the REML estimators are compared and the balanced incomplete block design (BIBD) is considered as a special case. The ML estimators are shown to have smaller asymptotic variances than the REML estimators, but a numerical result in the randomized complete block design (RCBD) demonstrated that the performances of the REML and ML estimators are not much different in the MSE sense.

A restricted maximum likelihood estimator for truncated height samples

The Maximum Likelihood (ML) and Best Linear Unbiased (BLU) estimators of the location and scale parameters of an extreme value distribution (Lawless [1982]) are compared under conditions of small sample sizes and Type I censorship. The comparisons were made in terms of the mean square error criterion. According to this criterion, the ML estimator of σ in the case of very small sample sizes (n < 10) and heavy censorship (low censoring time) proved to be more efficient than the corresponding BLU estimator. However, the BLU estimator for σ attains parity with the corresponding ML estimator when the censoring time increases even for sample sizes as low as 10. The BLU estimator of σ attains equivalence with the ML estimator when the sample size increases above 10, particularly when the censoring time is also increased. The situation is reversed when it came to estimating the location parameter μ, as the BLU estimator was found to be consistently more efficient than the ML estimator despite the improved performance of the ML estimator when the sample size increases. However, computational ease and convenience favor the ML estimators. Keywords: maximum likelihood estimatorsbest linear unbiased estimatorslife-testingreliability

The Multiple Comparison Procedures with Modeling Techniques (MCP-Mod) framework has been recently approved by the U.S. Food, Administration, and European Medicines Agency as fit-for-purpose for phase II studies. Nonetheless, this approach relies on the asymptotic properties of Maximum Likelihood (ML) estimators, which might not be reasonable for small sample sizes. In this paper, we derived improved ML estimators and correction for their covariance matrices in the censored Weibull regression model based on the corrective and preventive approaches. We performed two simulation studies to evaluate ML and improved ML estimators with their covariance matrices in (i) a regression framework (ii) the Multiple Comparison Procedures with Modeling Techniques framework. We have shown that improved ML estimators are less biased than ML estimators yielding Wald-type statistics that controls type I error without loss of power in both frameworks. Therefore, we recommend the use of improved ML estimators in the MCP-Mod approach to control type I error at nominal value for sample sizes ranging from 5 to 25 subjects per dose.

Over-the-air computation (OAC) is a promising technique to realize fast model aggregation in the uplink of federated edge learning (FEEL). OAC, however, hinges on accurate channel-gain precoding and strict synchronization among edge devices, which are challenging in practice. As such, how to design the maximum likelihood (ML) estimator in the presence of residual channel-gain mismatch and asynchronies is an open problem. To fill this gap, this paper formulates the problem of misaligned OAC for FEEL and puts forth a whitened matched filtering and sampling scheme to obtain oversampled, but independent samples from the misaligned and overlapped signals. Given the whitened samples, a sum-product ML (SP-ML) estimator and an aligned-sample estimator are devised to estimate the arithmetic sum of the transmitted symbols. In particular, the computational complexity of our SP-ML estimator is linear in the packet length, and hence is significantly lower than the conventional ML estimator. Extensive simulations on the test accuracy versus the average received energy per symbol to noise power spectral density ratio (EsN0) yield two main results: 1) In the low EsN0 regime, the aligned-sample estimator can achieve superior test accuracy provided that the phase misalignment is not severe. In contrast, the ML estimator does not work well due to the error propagation and noise enhancement in the estimation process. 2) In the high EsN0 regime, the ML estimator attains the optimal learning performance regardless of the severity of phase misalignment. On the other hand, the aligned-sample estimator suffers from a test-accuracy loss caused by phase misalignment.

Finite mixtures of multivariate skew t (MST) distributions have proven to be useful in modelling heterogeneous data with asymmetric and heavy tail behaviour. Recently, they have been exploited as an effective tool for modelling flow cytometric data. A number of algorithms for the computation of the maximum likelihood (ML) estimates for the model parameters of mixtures of MST distributions have been put forward in recent years. These implementations use various characterizations of the MST distribution, which are similar but not identical. While exact implementation of the expectation-maximization (EM) algorithm can be achieved for `restricted' characterizations of the component skew t-distributions, Monte Carlo (MC) methods have been used to fit the `unrestricted' models. In this paper, we review several recent fitting algorithms for finite mixtures of multivariate skew t-distributions, at the same time clarifying some of the connections between the various existing proposals. In particular, recent results have shown that the EM algorithm can be implemented exactly for faster computation of ML estimates for mixtures with unrestricted MST components. The gain in computational time is effected by noting that the semi-infinite integrals on the E-step of the EM algorithm can be put in the form of moments of the truncated multivariate non-central t-distribution, similar to the restricted case, which subsequently can be expressed in terms of the non-truncated form of the central t-distribution function for which fast algorithms are available. We present comparisons to illustrate the relative performance of the restricted and unrestricted models, and demonstrate the usefulness of the recently proposed methodology for the unrestricted MST mixture, by some applications to three real datasets.

The reverberation power spectral density (PSD) is often required for dereverberation and noise reduction algorithms. In this work, we compare two maximum likelihood (ML) estimators of the reverberation PSD in a noisy environment. In the first estimator, the direct path is first blocked. Then, the ML criterion for estimating the reverberation PSD is stated according to the probability density function of the blocking matrix (BM) outputs. In the second estimator, the speech component is not blocked. Instead, the ML criterion for estimating the speech and reverberation PSD is stated according to the probability density function of the microphone signals. To compare the expected mean square error (MSE) between the two ML estimators of the reverberation PSD, the Cramer–Rao Bounds (CRBs) for the two ML estimators are derived. We show that the CRB for the joint reverberation and speech PSD estimator is lower than the CRB for estimating the reverberation PSD from the BM outputs. Experimental results show that the MSE of the two estimators indeed obeys the CRB curves. Experimental results of multimicrophone dereverberation and noise reduction algorithm show the benefits of using the ML estimators in comparison with another baseline estimators.

On the effect of ignoring correlation in the covariates when fitting linear mixed models

Laser pointing systems for small targets are mainly confronted with two pointing errors, jitter and boresight, arising due to atmospheric turbulence, mechanical vibrations and errors in optical alignment. Knowledge of these parameters provides information about the quality of the pointing and tracking system. In the past, several techniques have been investigated to estimate these parameters from returned laser signals. These include the key ratio technique, the chi-squared method and the maximum likelihood (ML) estimation technique. These techniques have been studied in the literature for Gaussian irradiance profiles. In particular, the ML estimation technique has been found to provide excellent results. In this paper, we extend the ML estimation technique from Gaussian profiles to near-Gaussian irradiance profiles. Our results show that the modified estimator performs much better than a direct application of the original ML estimator.

A maximum likelihood (ML) estimator is developed for determining time delay between signals received at two spatially separated sensors in the presence of uncorrelated noise. This ML estimator can be realized as a pair of receiver prefilters followed by a cross correlator. The time argument at which the correlator achieves a maximum is the delay estimate. The ML estimator is compared with several other proposed processors of similar form. Under certain conditions the ML estimator is shown to be identical to one proposed by Hannan and Thomson [10] and MacDonald and Schultheiss [21]. Qualitatively, the role of the prefilters is to accentuate the signal passed to the correlator at frequencies for which the signal-to-noise (S/N) ratio is highest and, simultaneously, to suppress the noise power. The same type of prefiltering is provided by the generalized Eckart filter, which maximizes the S/N ratio of the correlator output. For low S/N ratio, the ML estimator is shown to be equivalent to Eckart prefiltering.

Estimation of the cell probabilities in a two-way contingency table is considered when it is plausible that the table might have an independence structure relating to the two traits. In a classical nonparametric setup, the unrestricted maximum likelihood estimators of the cell probabilities are the corresponding sample proportions; under the assumption of independence, the restricted estimators are the product of the respective row and column sample proportions. The latter estimators behave better than the former when independence actually holds, but a different picture may emerge for possible departure from the assumed independence structure; the restricted estimators may be heavily biased, inefficient, and even inconsistent. For this reason, a preliminary test on independence based on the classical contingency chi-squared statistic may be conveniently incorporated in the formulation of a preliminary test estimator of the matrix of cell probabilities. Since, typically, we have a multiparameter estimation problem, a pretest or shrinkage estimator based on the classical Stein rule may also be formulated in the same vein. The primary objective of this article is to focus on the asymptotic distribution theory of all four estimators under the null hypothesis of independence as well as local Pitman-type alternatives. The bias and risk based on suitable quadratic loss functions of these estimators are considered in the same asymptotic setup, and these are then incorporated in the study of the asymptotic relative performance of these estimators. In the light of their asymptotic risks, neither the preliminary test nor the shrinkage estimators dominates the other, though each fares well relative to the unrestricted or the restricted maximum likelihood estimators.

Nonlinear mixed-effects models have received a great deal of attention in the statistical literature in recent years because of the flexibility they offer in handling the unbalanced repeated-measures data that arise in different areas of investigation, such as pharmacokinetics and economics. Several different methods for estimating the parameters in nonlinear mixed-effects model have been proposed. We concentrate here on two of them—maximum likelihood and restricted maximum likelihood. A rather complex numerical issue for (restricted) maximum likelihood estimation in nonlinear mixed-effects models is the evaluation of the log-likelihood function of the data, because it involves the evaluation of a multiple integral that, in most cases, does not have a closed-form expression. We consider here four different approximations to the log-likelihood, comparing their computational and statistical properties. We conclude that the linear mixed-effects (LME) approximation suggested by Lindstrom and Bates, the Laplacian approximation, and Gaussian quadrature centered at the conditional modes of the random effects are quite accurate and computationally efficient. Gaussian quadrature centered at the expected value of the random effects is quite inaccurate for a smaller number of abscissas and computationally inefficient for a larger number of abscissas. Importance sampling is accurate, but quite inefficient computationally.

In the present paper a mixed approach is proposed for the simultaneously estimation of regression and correlation structure parameters in multivariate probit models using generalized estimating equations for the former and pseudo-score equations for the latter. The finite sample properties of the corresponding estimators are compared to estimators proposed by Qu, Williams, Beck and Medendorp (1992) and Qu, Piedmonte and Williams (1994) using generalized estimating equations for both sets of parameters via a Monte Carlo experiment. As a `reference' estimator for an equicorrelation model, the maximum likelihood (ML) estimator of the random effects probit model is calculated. The results show the mixed approach to be the most robust approach in the sense that the number of datasets for which the corresponding estimates converged was largest relative to the other two approaches. Furthermore, the mixed approach led to the most efficient non-ML estimators and to very efficient estimators for regression and correlation structure parameters relative to the ML estimator if individual covariance matrices were used.

In estimation theory, the asymptotic (in the number of samples) efficiency of the Maximum Likelihood (ML) estimator is a well known result [1]. Nevertheless, in some scenarios, the number of snapshots may be small. We recently investigated the asymptotic behavior of the Stochastic ML (SML) estimator at high Signal to Noise Ratio (SNR) and finite number of samples [2] in the array processing framework: we proved the non-Gaussiannity of the SML estimator and we obtained the analytical expression of the variance for the single source case. In this paper, we generalize these results to multiple sources, and we obtain variance expressions which demonstrate the non-efficiency of SML estimates.

Cooperative communication combats the effects offadingwithoutthe need for multiple antennas.The cooperative networks use multiple distributed nodes that virtually behave like multiple antennas each having their own local oscillators. But the oscillators cause multiple Carrier Frequency Offsets (CFO), unknown channel gains and Multiple Timing Offsets (MTO). For a good performance of the system perfect synchronization is needed which is achieved by estimation and compensation of multiple offsets. Also, the coverage and capacity can be improved by employing intermediate nodes called relays within cooperative networks. These cooperative relay networks can perform in a better manner even when considering MCFOs, MTOs and unknown channel gains by having more computationally efficient decoders that can use Maximum Likelihood (ML) estimation subject to the Cramer-Rao Lower Bound (CRLB) on the variance of any impartial estimate. The simulation results show that frequency offset still exist after Amplify and Forward (AF) relaying. The performance of a conventional cooperative network seems to have improved with respect to Bit Error Rate of the system when an AF relay is hosted. The estimate of the frequency offset is chosen such that it gives the signal, a high probability of occurrence using ML estimator. In ML estimate, since the bias and variance is difficult to compute, a lower bound called the CRLB on the variance of any unbiased estimate is derived which is satisfied by the ML estimator.Keywords: AF, Cooperative Communication, CFO, ML Estimation and Compensation, OFDM