Rey-Osterrieth complex figure: Psychometric characteristics in a geriatric sample

The comparability of recall performance was examined on the Rey-Osterrieth Complex Figure, the Taylor Complex Figure, and the Modified Taylor Complex Figure as measures of visuospatial abilities and visual memory in 66 healthy Japanese university students. A between-subjects design was used in which each of the participants received the three figures. The interrater reliability of each was excellent. While the three figures yielded equivalent copy scores, the Taylor Complex Figure produced significantly higher scores than the other two on both short (3-min.) and delayed (30-min.) recall tests. There were no significant differences between recall scores of the Rey-Osterrieth and the Modified Taylor figures. These results are consistent with the findings of the 2002 study of English-speakers by Hubley and Tremblay, and support that the Modified Taylor Figure is superior to the original one for the companion figure to the Rey-Osterrieth Complex Figure.

Background/Aim. Regarding several cognitive domains, including visuospatial and visuoconstructional abilities, little is known about the differences between vascular dementia (VaD) subtypes, even in the most common sub-types, such as multi-infarct dementia (MID) and subcortical ischemic small vessel disease dementia (SSVD). This paper aimed to identify the differences between the performances on the Rey-Osterrieth Complex Figure (ROCF) test in MID and SSVD and correlate the ROCF scores in both groups with magnetic resonance imaging (MRI) ischemic lesion load. Methods. Sixty VaD patients with matching severity of dementia, age, and education were included in this study: 32 with SSVD and 28 with MID ac-cording to the NINDS-AIREN (National Institute of Neuro-logical Disorders and Stroke and Association Internationale pour la Recherch? et l'Enseignement en Neurosciences) neuroradiological criteria. A quantitative scoring system was performed. ROCF was given to all subjects in three test conditions: copy, immediate recall after 3 minutes, and delayed recall after 45 min. Magnetic resonance imaging (MRI) of the is-chemic brain volumes of anterior and posterior lesions, left and right hemispheric lesions, left and right-sided basal ganglia lesions, and total lesion load (TLL) were calculated in both groups. Results. The MID group was more impaired than SSVD on ROCF copy (p = 0.008), immediate recall (p= 0.005) and delayed recall (p = 0.001). There were significant correlations between ROCF copy score and the TLL (p < 0.05) and posterior brain lesion volume (p< 0.05) in the MID group. Conclusion. The importance of visuospatial, visuoconstructional deficit and impairment of visual memory is disregarded in VaD subtypes. These impairments are more severe in MID than SSVD and the deficit of ROCF copying in MID patients correlates with posterior and total MRI lesion volume.

Neuropsychological and motor deficits in Parkinson's disease that may contribute to driving impairment were examined in a cohort study comparing patients with Parkinson's disease (PD) to patients with Alzheimer's disease (AD) and to healthy elderly controls. Nondemented individuals with Parkinson's disease [Hoehn & Yahr (H&Y) stage I-III], patients with Alzheimer's disease [Clinical Demetia Rating scale (CDR) range 0-1], and elderly controls, who were actively driving, completed a neuropsychological battery and a standardized road test administered by a professional driving instructor. On-road driving ability was rated on number of driving errors and a global rating of safe, marginal, or unsafe. Overall, Alzheimer's patients were more impaired drivers than Parkinson's patients. Parkinson's patients distinguished themselves from other drivers by a head-turning deficiency. Drivers with neuropsychological impairment were more likely to be unsafe drivers in both disease groups compared to controls. Compared to controls, unsafe drivers with Alzheimer's disease were impaired across all neuropsychological measures except finger tapping. Driving performance in Parkinson's patients was related to disease severity (H&Y), neuropsychological measures [Rey Osterreith Complex Figure (ROCF), Trails B, Hopkins Verbal List Learning Test (HVLT)-delay], and specific motor symptoms (axial rigidity, postural instability), but not to the Unified Parkinson Disease Rating Scale (UPDRS) motor score. Multifactorial measures (ROCF, Trails B) were useful in distinguishing safe from unsafe drivers in both patient groups.

Clinicians often use the Rey Osterrieth Complex Figure (ROCF) to distinguish between global and local information processing deficits, despite the fact that its validity for making such a distinction has not been empirically evaluated. To address this question, a statistical procedure that examines the similarity between variables, also known as Faceted Smallest Space Analysis, was applied to the ROCF test protocols of patients with well-documented structural brain lesions. The study confirms the differentiation between global and local elements of the ROCF, particularly among left hemisphere-injured patients. Discriminant Function Analysis, however, shows that the right-sided local elements of the ROCF are the most useful for discriminating between right- and left-hemisphere-damaged patients. The present study suggests that the processing of the ROCF is dependent on both the spatial characteristics and location of its elements.

Spatial disorientation is a hallmark of amnestic mild cognitive impairment (aMCI) and Alzheimer's disease. Our aim was to use virtual reality to determine the allocentric and egocentric memory deficits of subjects with single-domain aMCI (aMCIsd) and multiple-domain aMCI (aMCImd). For this purpose, we introduced an advanced virtual reality navigation task (VRNT) to distinguish these deficits in mild Alzheimer's disease (miAD), aMCIsd, and aMCImd. The VRNT performance of 110 subjects, including 20 with miAD, 30 with pure aMCIsd, 30 with pure aMCImd, and 30 cognitively normal controls was compared. Our newly developed VRNT consists of a virtual neighbourhood (allocentric memory) and virtual maze (egocentric memory). Verbal and visuospatial memory impairments were also examined with Rey Auditory-Verbal Learning Test and Rey-Osterrieth Complex Figure Test, respectively. We found that miAD and aMCImd subjects were impaired in both allocentric and egocentric memory, but aMCIsd subjects performed similarly to the normal controls on both tasks. The miAD, aMCImd, and aMCIsd subjects performed worse on finding the target or required more time in the virtual environment than the aMCImd, aMCIsd, and normal controls, respectively. Our findings indicated the aMCImd and miAD subjects, as well as the aMCIsd subjects, were more impaired in egocentric orientation than allocentric orientation. We concluded that VRNT can distinguish aMCImd subjects, but not aMCIsd subjects, from normal elderly subjects. The VRNT, along with the Rey Auditory-Verbal Learning Test and Rey-Osterrieth Complex Figure Test, can be used as a valid diagnostic tool for properly distinguishing different forms of aMCI.

The aim of this study was to analyze ADHD diagnosed children´s process of copy, organization strategies and recall phase of Rey-Osterrieth Complex Figure. This study corresponds to an ex post facto retrospective design with two groups, one quasi control. Seventy children between 8 and 14 years old were evaluated; 35 with ADHD and 35 without these diagnoses, paired by sex, age and instruction level. To reach the proposed objective, the process of copying, organizational strategies and memory of the Rey- Osterrieth Complex Figure were evaluated. The Rey-Osterrieth Complex Figure is a test which consists of copying phase and posterior playing back memory phase of a complex geometric pattern. Results showed a lower yield for the group with ADHD both in copy and memory process, with greater use of C and D types of copy reproduction, being the use of type D expected for younger children. These results allow further analysis of the performance of children with ADHD regarding organizational strategies providing expertise in the conceptualization, evaluation and treatment of the disorder.

The degree to which the Rey-Osterrieth and Taylor complex figures provide equivalent measures of visual memory, and the effects of age on figure comparability were examined in two experiments. Both experiments employed a multiple-trial, intentional learning procedure wherein each figure was administered twice in a counterbalanced sequence to subjects aged 20 to 80 years. In Experiment 1, a constant 60-s exposure duration was used; in Experiment 2, a self-pacing procedure was employed where the exposure duration was individually determined. The results from both experiments showed that the Taylor figure was easier to learn than the Rey-Osterrieth figure, indicating that the two figures are not equivalent for testing memory. These results were supported by subjective judgements on the relative difficulty to learn and remember each figure. Finally, younger (20-59 years) subjects performed at a higher level than older (60-80 years) subjects on both figures. Recommendations and possible alternatives are suggested regarding the use of the figures in both constructional and visuo-spatial memory test-retest situations.

The ability of the Rey-Osterrieth (R-O) and Taylor complex figures to produce equivalent scores on both constructional and memory tasks was examined in four studies. While the two figures yielded equivalent copy scores, the Taylor figure produced significantly higher scores on memory tests. This latter relationship was observed with three different retention conditions (immediate, 20-min, and 1-month recall), two types of learning paradigms (incidental and intentional), and two scoring systems (itemized and clinical neuropsychological). The failure to obtain equivalent recall scores cautions against using the R-O and Taylor as companion figures to evaluate normal recovery and treatment effectiveness on mnemonic processes. The relative merits of using an intentional rather than an incidental procedure to administer the figures in test-retest situations are discussed.

Our aims were to evaluate the neurocognitive performance in adolescents with congenital heart disease (CHD) and to determine whether parameters of fetal development evaluated in neonates, such as head circumference, length, weight, and Apgar scores, are somehow related to their neurocognitive performance. We evaluated 77 CHD patients (43 males) aged from 13 to 18 years old (mean = 15.04 ± 1.86), 46 cyanotic, 23 with tetralogy of Fallot (TF), 23 with transposition of the great arteries (TGA) and 31 acyanotic with ventricular septal defect (VSD) enrolled in this study. The control group included 16 healthy children (11 males) ages ranging from 13 to 18 years old (mean = 15.69 years ± 1.44 years). All assessment measures for CHD patients were once obtained in a tertiary hospital; the control group was evaluated in school. Neuropsychological assessment included Wechsler's Digit Test, direct and reverse (WDD and WDR) and Symbol Search, Rey's Complex Figure (RCF), BADS's Key Searching Test, Color-Word Stroop Test (CWS), Trail Making Test (TMT), and Logical Memory Task (LMT). We evaluated some fetal parameters, such as head circumference, weight and length assessed at birth, and neonatal parameters, such as Apgar scores at 1 and 5 minutes after birth. We also registered some surgical parameters, such as the age at first operation and the number of surgeries. CHD patients compared with control group showed lower scores on every test, except for logical memory task. Patients with VSD when compared with patients with TF and TGA showed better results in all neuropsychological tests, although the only significant differences were in RCF, copy (F = 4936; P = .010). Several correlations were apparent between fetal/neonatal parameters and neuropsychological abilities in each type of CHD. However, head circumference at birth stands as the main correlation with cognitive development later on in all kinds of CHD (WDD: rho = .339, P = .011; RCF, copy: rho = 0.297, P = .027; CWS, interference: rho = 0.283, P = .036; TMT-A: rho = -0.321, P = .017). We analyzed the predicting relevance of several variables to cognitive performance of adolescents with CHD and confirmed that "cyanosis" stands as the main predictor (â = -4.758; t = -2.622; P = .011). Adolescents with CHD have worse neuropsychological performance than the control group, mainly the cyanotic patients. Fetal circulation seems to have impact on cerebral and somatic growth, predicting cognitive impairment in adolescents with CHD.

Interrater and internal consistency reliabilities were computed for the Boston Qualitative Scoring System, a newly developed system for scoring the Rey-Osterrieth Complex Figure. Subjects (N = 108) included males with right hemisphere stroke (n = 46), left hemisphere stroke (n = 20), dementia (n = 21), and normal controls (n = 21). Interrater reliability coefficients for all scales except asymmetry, which had a reliability coefficient of .2013, ranged from .6342 to .9919, with most in the good to excellent range. Internal consistency reliabilities ranged from .7774 to .9128, also with most in the good to excellent range. Discriminant indices of visuospatial accuracy scales found the scoring system to be useful in distinguishing between individuals based on visuospatial scores

Neuropsychological Profile of a Large Kindred with Familial Alzheimer's Disease Caused by the E280A Single Presenilin-1 Mutation

Significant association between catechol-O-methyltransferase (COMT) Val158/108Met polymorphism and cognitive function in veterans with PTSD

Memory deficits are a hallmark of many different neurological and psychiatric conditions. The Rey–Osterrieth complex figure (ROCF) is the state-of-the-art assessment tool for neuropsychologists across the globe to assess the degree of non-verbal visual memory deterioration. To obtain a score, a trained clinician inspects a patient’s ROCF drawing and quantifies deviations from the original figure. This manual procedure is time-consuming, slow and scores vary depending on the clinician’s experience, motivation, and tiredness. Here, we leverage novel deep learning architectures to automatize the rating of memory deficits. For this, we collected more than 20k hand-drawn ROCF drawings from patients with various neurological and psychiatric disorders as well as healthy participants. Unbiased ground truth ROCF scores were obtained from crowdsourced human intelligence. This dataset was used to train and evaluate a multihead convolutional neural network. The model performs highly unbiased as it yielded predictions very close to the ground truth and the error was similarly distributed around zero. The neural network outperforms both online raters and clinicians. The scoring system can reliably identify and accurately score individual figure elements in previously unseen ROCF drawings, which facilitates explainability of the AI-scoring system. To ensure generalizability and clinical utility, the model performance was successfully replicated in a large independent prospective validation study that was pre-registered prior to data collection. Our AI-powered scoring system provides healthcare institutions worldwide with a digital tool to assess objectively, reliably, and time-efficiently the performance in the ROCF test from hand-drawn images.

The Rey–Osterrieth Complex Figure (ROCF) test is a commonly used neuropsychological assessment tool. It is widely used to assess the visuo-constructional ability and visual memory of neuropsychiatric disorders, including copying and recall tests. By drawing the complex figure, the functional decline of a patient in multiple cognitive dimensions can be assessed, including attention and concentration, fine-motor coordination, visuospatial perception, non-verbal memory, planning and organization, and spatial orientation. This review first describes the different versions and scoring methods of ROCF. It then reviews the application of ROCF in the assessment of visuo-constructional ability in patients with dementia, other brain diseases, and psychiatric disorders. Finally, based on the scoring method of the digital system, future research hopes to develop a new digital ROCF scoring method combined with machine learning algorithms to standardize clinical practice and explore the characteristic neuropsychological structure information of different disorders.

BackgroundIdentifying cognitive markers for early detection of neurodegenerative disorders is crucial for understanding pathological aging. Given the early impact of information acquisition, consolidation, and retrieval processes in Alzheimer's disease (Jutten et al., 2020), this study aims to determine whether immediate or delayed recall processes at baseline can effectively differentiate between individuals with stable mild cognitive impairment (MCI) and those who convert to Alzheimer's Clinical Syndrome (ACS) after two years.MethodA cohort of 140 older adults diagnosed with MCI (62.4% female, mean age = 76.27, SD = 5.71) underwent baseline neuropsychological assessment, including the Spanish version of the California Verbal Learning Test (CVLT‐TAVEC), the Rey–Osterrieth Complex Figure Test (ROCF), and Verbal Paired Associates (Wechsler Memory Scale). After a two‐year follow‐up, 24 participants progressed to ACS (MCI‐converters). Binary logistic regression and ROC curve analyses were performed to determine whether immediate or delayed recall measures at baseline were more effective in predicting conversion.ResultBinary logistic regression revealed that immediate recall performance on both verbal (CVLT‐TAVEC) and visual (ROCF) memory tests significantly predicted conversion to ACS within two years (p < 0.001). Participants who later developed ACS showed significantly lower baseline scores on short‐term recall tasks compared to those who remained stable (p < 0.001). ROC curve analyses demonstrated that CVLT‐TAVEC immediate recall (AUC = 0.815, p < 0.000) was a stronger predictor of conversion than long‐term recall (AUC = 0.804, p < 0.000).ConclusionThese findings highlight immediate consolidation deficits as a potential early marker of prodromal Alzheimer's disease, emphasizing their role in the preclinical trajectory of AD. The results suggest that immediate recall impairments, rather than delayed recall deficits, may better capture the earliest cognitive dysfunctions associated with disease progression. Incorporating short‐term recall measures into clinical assessments could improve the early identification of high‐risk individuals and refine predictive models for AD. Further research is needed to explore the underlying neural mechanisms linking immediate consolidation to Alzheimer's pathology.