Segmentation of Craniomaxillofacial Bony Structures from MRI with a 3D Deep-Learning Based Cascade Framework.

Compared to computed tomography (CT), magnetic resonance imaging (MRI) delineation of craniomaxillofacial (CMF) bony structures can avoid harmful radiation exposure. However, bony boundaries are blurry in MRI, and structural information needs to be borrowed from CT during the training. This is challenging since paired MRI-CT data are typically scarce. In this paper, we propose to make full use of unpaired data, which are typically abundant, along with a single paired MRI-CT data to construct a one-shot generative adversarial model for automated MRI segmentation of CMF bony structures. Our model consists of a cross-modality image synthesis sub-network, which learns the mapping between CT and MRI, and an MRI segmentation sub-network. These two sub-networks are trained jointly in an end-to-end manner. Moreover, in the training phase, a neighbor-based anchoring method is proposed to reduce the ambiguity problem inherent in cross-modality synthesis, and a feature-matching-based semantic consistency constraint is proposed to encourage segmentation-oriented MRI synthesis. Experimental results demonstrate the superiority of our method both qualitatively and quantitatively in comparison with the state-of-the-art MRI segmentation methods.

Hybrid CNN-transformer network for interactive learning of challenging musculoskeletal images

Medical imaging is essential for diagnosing and managing diseases that impact human organs. Two widely used imaging techniques, Computed Tomography (CT) and Magnetic Resonance Imaging (MRI), offer valuable information about the structural aspects of organs. However, relying solely on a single imaging modality can sometimes limit disease detection accuracy. To address this limitation, the integration of multiple modalities followed by segmentation has gained traction, offering improved precision in assessing organ health. Accurate segmentation of organs from multi-modal medical images forms the cornerstone of modern healthcare, facilitating precise treatment planning, early disease detection, and personalized medicine. This paper offers an in-depth review of the latest trends and challenges in abdominal organ segmentation using deep learning approaches. It explores the use of attention mechanisms, Graph Neural Networks (GNNs) alongside traditional methods such as Convolutional Neural Networks (CNN), Fully Convolutional Networks (FCN), and Generative Adversarial Networks (GAN) within the scope of abdominal organ segmentation. The paper also addresses key challenges and opportunities in the field, highlighting the importance of continued innovation and collaboration to advance abdominal organ segmentation for improved clinical outcomes.

Cardiac Magnetic Resonance (CMR) imaging is commonly used to assess cardiac structure and function. One disadvantage of CMR is that postprocessing of exams is tedious. Without automation, precise assessment of cardiac function via CMR typically requires an annotator to spend tens of minutes per case manually contouring ventricular structures. Automatic contouring can lower the required time per patient by generating contour suggestions that can be lightly modified by the annotator. Fully convolutional networks (FCNs), a variant of convolutional neural networks, have been used to rapidly advance the state-of-the-art in automated segmentation, which makes FCNs a natural choice for ventricular segmentation. However, FCNs are limited by their computational cost, which increases the monetary cost and degrades the user experience of production systems. To combat this shortcoming, we have developed the FastVentricle architecture, an FCN architecture for ventricular segmentation based on the recently developed ENet architecture. FastVentricle is 4\(\times \) faster and runs with 6\(\times \) less memory than the previous state-of-the-art ventricular segmentation architecture while still maintaining excellent clinical accuracy.

Understanding the spatial distribution of irrigated croplands is crucial for food security and water use. To map land cover classes with high-spatial-resolution images, it is necessary to analyze the semantic information of target objects in addition to the spectral or spatial–spectral information of local pixels. Deep convolutional neural networks (DCNNs) can characterize the semantic features of objects adaptively. This study uses DCNNs to extract irrigated croplands from Sentinel-2 images in the states of Washington and California in the United States. We integrated the DCNNs of 101 layers, discarded pooling layers, and employed dilation convolution to preserve location information; these are models which were used based on fully convolutional network (FCN) architectures. The findings indicated that irrigated croplands may be effectively detected at various phases of crop growth in the fields. A quantitative analysis of the trained models revealed that the three models in the two states had the lowest values of Intersection over Union (IoU) and Kappa, i.e., 0.88 and 0.91, respectively. The deep models’ temporal portability across different years was acceptable. The lowest values of recall and OA (overall accuracy) from 2018 to 2021 were 0.91 and 0.87, respectively. In Washington, the lowest OA value from 10 to 300 m resolution was 0.76. This study demonstrates the potential of FCNs + DCNNs approaches for mapping irrigated croplands across large regions, providing a solution for irrigation mapping. The spatial resolution portability of deep models could be improved further by designing model architectures.

We present the application of limited one-time sampling irregularity map (LOTS-IM): a fully automatic unsupervised approach to extract brain tissue irregularities in magnetic resonance images (MRI), for quantitatively assessing white matter hyperintensities (WMH) of presumed vascular origin, and multiple sclerosis (MS) lesions and their progression. LOTS-IM generates an irregularity map (IM) that represents all voxels as irregularity values with respect to the ones considered ”normal”. Unlike probability values, IM represents both regular and irregular regions in the brain based on the original MRI's texture information. We evaluated and compared the use of IM for WMH and MS lesions segmentation on T2-FLAIR MRI with the state-of-the-art unsupervised lesions’ segmentation method, Lesion Growth Algorithm from the public toolbox Lesion Segmentation Toolbox (LST-LGA), with several well established conventional supervised machine learning schemes and with state-of-the-art supervised deep learning methods for WMH segmentation. In our experiments, LOTS-IM outperformed unsupervised method LST-LGA on WMH segmentation, both in performance and processing speed, thanks to the limited one-time sampling scheme and its implementation on GPU. Our method also outperformed supervised conventional machine learning algorithms (i.e., support vector machine (SVM) and random forest (RF)) and deep learning algorithms (i.e., deep Boltzmann machine (DBM) and convolutional encoder network (CEN)), while yielding comparable results to the convolutional neural network schemes that rank top of the algorithms developed up to date for this purpose (i.e., UResNet and UNet). LOTS-IM also performed well on MS lesions segmentation, performing similar to LST-LGA. On the other hand, the high sensitivity of IM on depicting signal change deems suitable for assessing MS progression, although care must be taken with signal changes not reflective of a true pathology.

Prognostic indicators of the outcome of arthrocentesis: a short-term follow-up study.

Segmentation of white matter, grey matter and cerebrospinal fluid from brain MR images using a modified FCM based on double estimation

Early detection and treatment are crucial for recovery from cancer. Due to rapid advancement in medical imaging techniques, today doctors can scan various body parts from different perspectives to diagnose cancer or see the progress during a course of treatment. Such techniques are less painful and require less preparation and recovery. The recent evolution of AI, particularly deep learning algorithms have shown potential in computer-aided diagnosis of cancer. These include analysis of cancer images for detection of tumor region, prognosis, skin tissue inspection, etc. Convolutional Neural Network (CNN) based image processing techniques are showing promising results in the diagnosis of breast cancer, skin cancer, prostate cancer, lung cancer, etc. Literature shows many other CNN-based models such as feed-forward neural network, Deep CNN, Multi-Crop CNN, fully convolutional networks (FCNs), Deep Fully Convolutional Network (DFCNet), Recurrent neural networks, etc. The CNN focus solely on the image-specific features and hence require a lesser number of input parameters. A CNN model reduces the size of the input image vector without losing the features critical for making an accurate prediction. This makes it easier to process and reduces computational complexity. CNNs are also not sensitive to the object positioning in an image since the approximate position of image motifs relative to others is known. CNN deals with the variations in images through augmentation and other pre-processing techniques. This makes them robust to various straining conditions in images. This chapter presents an overview of a generic CNN architecture followed by a discussion on major advances in CNN models and their applications for cancer image analysis.

Differential diagnosis of facial pain and guidelines for management

To evaluate the performance, agreement, and efficiency of a fully convolutional network (FCN) for liver lesion detection and segmentation at CT examinations in patients with colorectal liver metastases (CLMs). This retrospective study evaluated an automated method using an FCN that was trained, validated, and tested with 115, 15, and 26 contrast material-enhanced CT examinations containing 261, 22, and 105 lesions, respectively. Manual detection and segmentation by a radiologist was the reference standard. Performance of fully automated and user-corrected segmentations was compared with that of manual segmentations. The interuser agreement and interaction time of manual and user-corrected segmentations were assessed. Analyses included sensitivity and positive predictive value of detection, segmentation accuracy, Cohen κ, Bland-Altman analyses, and analysis of variance. In the test cohort, for lesion size smaller than 10 mm (n = 30), 10-20 mm (n = 35), and larger than 20 mm (n = 40), the detection sensitivity of the automated method was 10%, 71%, and 85%; positive predictive value was 25%, 83%, and 94%; Dice similarity coefficient was 0.14, 0.53, and 0.68; maximum symmetric surface distance was 5.2, 6.0, and 10.4 mm; and average symmetric surface distance was 2.7, 1.7, and 2.8 mm, respectively. For manual and user-corrected segmentation, κ values were 0.42 (95% confidence interval: 0.24, 0.63) and 0.52 (95% confidence interval: 0.36, 0.72); normalized interreader agreement for lesion volume was -0.10 ± 0.07 (95% confidence interval) and -0.10 ± 0.08; and mean interaction time was 7.7 minutes ± 2.4 (standard deviation) and 4.8 minutes ± 2.1 (P < .001), respectively. Automated detection and segmentation of CLM by using deep learning with convolutional neural networks, when manually corrected, improved efficiency but did not substantially change agreement on volumetric measurements.© RSNA, 2019Supplemental material is available for this article.

ABSTRACTThe aim of this study was to investigate the pathological changes of the lateral pterygoid muscle (LPM) using magnetic resonance imaging (MRI) in patients with anterior disk displacement with nonreduction (ADDnr) of the temporomandibular joint (TMJ) and to compare the abnormal findings of the LPM with the clinical symptoms and other pathological MRI alterations of the TMJ. Bilateral or unilateral ADDnr was demonstrated in 142 patients by MRI (176 TMJs; 106 females; 36 males; range 19 to 72 years; mean 43.9 years). In 123 TMJs, the LPMs were clearly observed in MRIs and analyzed in this study. Pathological changes of the LPM were found in 92 TMJs (74.8%) in MRI. Hypertrophy, atrophy and/or contracture were detected in the superior belly of the LPM (SBLPM) (35.8%, 44/123) or in the inferior belly of the LPM (IBLPM) (9.8%, 12/123) or in both bellies (29.3%, 36/123). The pathological changes of the LPM in MRI presented a significant association with the main clinical symptoms of TMJs with ADDnr, i.e. pain on jaw movement (P<0.01), pain in the LPM (P<0.01), pain in TMJ (P<0.05) and restricted jaw opening (P<0.05). The proportion of the abnormalities in LPM was significantly lower in TMJs with condylar limitation (63.6%) than in TMJs with condylar hypermobility (83.3%) and normal motion (88.9%)(P=0.008). Osteoarthritis was found to be correlated with condylar limitation (P<0.01). The results of this study indicate that the pathological changes of the LPM in TMJs with ADDnr could be detected by MRI and have a significant association with the main clinical symptoms of the patients. When condylar limitation happened, on the contrary, the pathological changes of the LPM in MRI were reduced. The alteration of the clinical symptoms in the patients with ADDnr might be associated with the pathological situations and symptoms of the LPM.

Land cover is an important variable of the terrestrial ecosystem that provides information for natural resources management, urban sprawl detection, and environment research. To classify land cover with high-spatial-resolution multispectral remote sensing imagery is a difficult problem due to heterogeneous spectral values of the same object on the ground. Fully convolutional networks (FCNs) are a state-of-the-art method that has been increasingly used in image segmentation and classification. However, a systematic quantitative comparison of FCNs on high-spatial-multispectral remote imagery was not yet performed. In this paper, we adopted the three FCNs (FCN-8s, Segnet, and Unet) for Gaofen-2 (GF2) satellite imagery classification. Two scenes of GF2 with a total of 3329 polygon samples were used in the study area and a systematic quantitative comparison of FCNs was conducted with red, green, blue (RGB) and RGB+near infrared (NIR) inputs for GF2 satellite imagery. The results showed that: (1) The FCN methods perform well in land cover classification with GF2 imagery, and yet, different FCNs architectures exhibited different results in mapping accuracy. The FCN-8s model performed best among the Segnet and Unet architectures due to the multiscale feature channels in the upsampling stage. Averaged across the models, the overall accuracy (OA) and Kappa coefficient (Kappa) were 5% and 0.06 higher, respectively, in FCN-8s when compared with the other two models. (2) High-spatial-resolution remote sensing imagery with RGB+NIR bands performed better than RGB input at mapping land cover, and yet the advantage was limited; the OA and Kappa only increased an average of 0.4% and 0.01 in the RGB+NIR bands. (3) The GF2 imagery provided an encouraging result in estimating land cover based on the FCN-8s method, which can be exploited for large-scale land cover mapping in the future.

Farmland is the cornerstone of agriculture and is important for food security and social production. Farmland assessment is essential but traditional methods are usually expensive and slow. Deep learning methods have been developed and widely applied recently in image recognition, semantic understanding, and many other application domains. In this research, we used fully convolutional networks (FCN) as the deep learning model to evaluate farmland grades. Normalized difference vegetation index (NDVI) derived from Landsat images was used as the input data, and the China National Cultivated Land Grade Database within Jiangsu Province was used to train the model on cloud computing. We also applied an image segmentation method to improve the original results from the FCN and compared the results with classical machine learning (ML) methods. Our research found that the FCN can predict farmland grades with an overall F1 score (the harmonic mean of precision and recall) of 0.719 and F1 score of 0.909, 0.590, 0.740, 0.642, and 0.023 for non-farmland, level I, II, III, and IV farmland, respectively. Combining the FCN and image segmentation method can further improve prediction accuracy with results of fewer noise pixels and more realistic edges. Compared with conventional ML, at least in farmland evaluation, FCN provides better results with higher precision, recall, and F1 score. Our research indicates that by using remote sensing NDVI data, the deep learning method can provide acceptable farmland assessment without fieldwork and can be used as a novel supplement to traditional methods. The method used in this research will save a lot of time and cost compared with traditional means.

Cranial Ultrasonography