Separability Analysis of Color Classes on Dermoscopic Images

Any cancer type is one of the leading death causes around the world. Skin cancer is a condition where malignant cells are formed in the tissues of the skin, such as melanoma, known as the most aggressive and deadly skin cancer type. The mortality rates of melanoma are associated with its high potential for metastasis in later stages, spreading to other body sites such as the lungs, bones, or the brain. Thus, early detection and diagnosis are closely related to survival rates. Computer Aided Design (CAD) systems carry out a pre-diagnosis of a skin lesion based on clinical criteria or global patterns associated with its structure. A CAD system is essentially composed by three modules: (i) lesion segmentation, (ii) feature extraction, and (iii) classification. In this work, a methodology is proposed for a CAD system development that detects global patterns using texture descriptors based on statistical measurements that allow melanoma detection from dermoscopic images. Image analysis was carried out using spatial domain methods, statistical measurements were used for feature extraction, and a classifier based on cellular automata (ACA) was used for classification. The proposed model was applied to dermoscopic images obtained from the PH2 database, and it was compared with other models using accuracy, sensitivity, and specificity as metrics. With the proposed model, values of 0.978, 0.944, and 0.987 of accuracy, sensitivity and specificity, respectively, were obtained. The results of the evaluated metrics show that the proposed method is more effective than other state-of-the-art methods for melanoma detection in dermoscopic images.

SSM-Net: Semi-supervised multi-task network for joint lesion segmentation and classification from pancreatic EUS images

<p>This paper presents a review of the state-of-the-art in histopathology image representation used in automatic image analysis tasks. Automatic analysis of histopathology images is important for building computer-assisted diagnosis tools, automatic image enhancing systems and virtual microscopy systems, among other applications. Histopathology images have a rich mix of visual patterns with particularities that make them difficult to analyze. The paper discusses these particularities, the acquisition process and the challenges found when doing automatic analysis. Second an overview of recent works and methods addressed to deal with visual content representation in different automatic image analysis tasks is presented. Third an overview of applications of image representation methods in several medical domains and tasks is presented. Finally, the paper concludes with current trends of automatic analysis of histopathology images like digital pathology.</p>

Image quality assessment is essential for retinopathy detection on color fundus retinal image. However, most studies focused on the classification of good and poor quality without considering the different types of poor quality. This study developed an automatic retinal image analysis (ARIA) method, incorporating transfer net ResNet50 deep network with the automatic features generation approach to automatically assess image quality, and distinguish eye-abnormality-associated-poor-quality from artefact-associated-poor-quality on color fundus retinal images. A total of 2434 retinal images, including 1439 good quality and 995 poor quality (483 eye-abnormality-associated-poor-quality and 512 artefact-associated-poor-quality), were used for training, testing, and 10-ford cross-validation. We also analyzed the external validation with the clinical diagnosis of eye abnormality as the reference standard to evaluate the performance of the method. The sensitivity, specificity, and accuracy for testing good quality against poor quality were 98.0%, 99.1%, and 98.6%, and for differentiating between eye-abnormality-associated-poor-quality and artefact-associated-poor-quality were 92.2%, 93.8%, and 93.0%, respectively. In external validation, our method achieved an area under the ROC curve of 0.997 for the overall quality classification and 0.915 for the classification of two types of poor quality. The proposed approach, ARIA, showed good performance in testing, 10-fold cross validation and external validation. This study provides a novel angle for image quality screening based on the different poor quality types and corresponding dealing methods. It suggested that the ARIA can be used as a screening tool in the preliminary stage of retinopathy grading by telemedicine or artificial intelligence analysis.

Digital image analysis as a tool to quantify gaping and morphology in smoked salmon slices

The classification of skin lesions in dermoscopy images depends on three critical steps: i) lesion segmentation, ii) feature extraction and iii) feature classification. Lesion segmentation plays an important role since segmentation errors may jeopardize the other two steps, leading to erroneous decisions. This paper studies the robustness of a skin lesion classifier based on a Bag-of-features approach in the presence of segmentation errors. We compare the performance achieved by the system using an automatic segmentation algorithm with the performance obtained using manual segmentation provided by a specialist. We observe a degradation of the system accuracy by 8% when automatic segmentation is used. We also show that these results can be improved if manually segmented images are used in training phase, keeping a fully automatic solution during the testing phase.

The combination of automatic image acquisition and automatic image analysis of premature chromosome condensation (PCC) spreads was tested as a rapid biodosimeter protocol. Human peripheral lymphocytes were irradiated with 60Co gamma rays in a single dose of between 1 and 20 Gy, stimulated with phytohaemaglutinin and incubated for 48 h, division blocked with Colcemid, and PCC-induced by Calyculin A. Images of chromosome spreads were captured and analysed automatically by combining the Metafer 4 and CellProfiler platforms. Automatic measurement of chromosome lengths allows the calculation of the length ratio (LR) of the longest and the shortest piece that can be used for dose estimation since this ratio is correlated with ionizing radiation dose. The LR of the longest and the shortest chromosome pieces showed the best goodness-of-fit to a linear model in the dose interval tested. The application of the automatic analysis increases the potential use of the PCC method for triage in the event of massive radiation causalities.

automatic quantitative image analysis system for con- struction materials.

Grain-shape analyses are essential in geological research because they provide the basis for genetic interpretations, including sedimentation conditions. The methods of visual evaluation used so far have been subjective, time-consuming and labour intensive. Automatic particle image analysis, including the methods used by the Morphology G3SE device, open up the possibility of mass and objective roundness analysis of mineral and organic particles. The article presents the results of measurements for the grain scale proposed by Krumbein in 1941, as this scale has been used in numerous sedimentological studies. The standard shapes were analysed using four parameters: High Sensitivity (HS) Circularity, Convexity, Solidity and Aspect Ratio. In the discussion, both the results and the grain-shape standards were critically assessed. The most important trends in the distribution of morphometric parameters of the scale are shown. On this basis, it was found that it is impossible to determine the parameter boundary values that would distinguish each class of grain roundness proposed by Krumbein. The conclusions propose criteria for the automatic differentiation of angular, subrounded and rounded grains, which could be a basis for describing the shape of mineral particles.

Radiological follow-up of oncology patients requires the detection of metastatic lung lesions and the quantitative analysis of their changes in longitudinal imaging studies. Our aim was to evaluate SimU-Net, a novel deep learning method for the automatic analysis of metastatic lung lesions and their temporal changes in pairs of chest CT scans. SimU-Net is a simultaneous multichannel 3D U-Net model trained on pairs of registered prior and current scans of a patient. It is part of a fully automatic pipeline for the detection, segmentation, matching, and classification of metastatic lung lesions in longitudinal chest CT scans. A data set of 5040 metastatic lung lesions in 344 pairs of 208 prior and current chest CT scans from 79 patients was used for training/validation (173 scans, 65 patients) and testing (35 scans, 14 patients) of a standalone 3D U-Net models and 3 simultaneous SimU-Net models. Outcome measures were the lesion detection and segmentation precision, recall, Dice score, average symmetric surface distance (ASSD), lesion matching, and classification of lesion changes from computed versus manual ground-truth annotations by an expert radiologist. SimU-Net achieved a mean lesion detection recall and precision of 0.93±0.13 and 0.79±0.24 and a mean lesion segmentation Dice and ASSD of 0.84±0.09 and 0.33±0.22mm. These results outperformed the standalone 3D U-Net model by 9.4% in the recall, 2.4% in Dice, and 15.4% in ASSD, with a minor 3.6% decrease in precision. The SimU-Net pipeline achieved perfect precision and recall (1.0±0.0) for lesion matching and classification of lesion changes. Simultaneous deep learning analysis of metastatic lung lesions in prior and current chest CT scans with SimU-Net yields superior accuracy compared with individual analysis of each scan. Implementation of SimU-Net in the radiological workflow may enhance efficiency by automatically computing key metrics used to evaluate metastatic lung lesions and their temporal changes.

Semi-automatic segmentation of skin lesions based on superpixels and hybrid texture information.

Skin cancer is the most commonly diagnosed cancer worldwide. It is estimated that there are over 5 million cases of skin cancer are diagnosed in the United States every year. Although less than 5% of all diagnosed skin cancers are melanoma it accounts for over 70% of skin cancer-related deaths. In the past decade, the number of melanoma cancer cases has increased by 53%. Recently, there has been significant work on segmentation and classification of skin lesions via deep learning. However, there is limited work on identifying attributes and clinically-meaningful visual skin lesion patterns from dermoscopic images. In this work, we propose to use conditional GANs for skin lesion segmentation and attribute detection and use these attributes to improve skin lesion classification. The proposed conditional GAN framework can generate segmentation and attribute masks from RGB dermoscopic images. The adversarial-image-to-image translation style architecture forces the generator to learn both local and global features. The Markovian discriminator classifies pairs of image and segmentation labels as being real or fake. Unlike previous approaches, such an architecture not only learns the mapping from dermoscopic images image to segmentation and attribute masks but also learns an optimal loss function to train such a mapping. We demonstrate that the such an approach significantly improves the Jaccard index for segmentation (with a 0.65 threshold) up to 0.893. Fusing the lesion attributes for classification of lesions yields a higher accuracy compared to those without predicted attributes.

Reliability of textural analysis of ancient plasters and mortars through automated image analysis

<i>In vivo</i> measurements of muscle volume by automatic image analysis of spiral computed tomography scans

Deep learning (DL) is increasingly explored in interventional radiology (IR) applications. This systematic review evaluates current DL-based applications for digital subtraction angiography (DSA) in abdominopelvic interventions, summarizes performance, and identifies gaps in the literature. Following PRISMA guidelines, we searched MEDLINE, Scopus, and Google Scholar for studies published up to February 1, 2025. English-language original articles assessing DL methods for automatic DSA image analysis were included, and study quality was evaluated with QUADAS-2. Nine studies were included. Two focused on hemorrhage detection, in which area under the curve (AUC) values ranged between 0.80-0.85. Four examined image enhancement, one performed vessel segmentation, and one applied classification of the anatomic location. Only a single study evaluated treatment response prediction, with an accuracy of 0.75. Most models were tested on small datasets from single centers, limiting their generalizability. Preliminary studies show that DL can improve hemorrhage detection, image quality, and vessel segmentation in DSA. However, larger, prospectively validated datasets are warranted. Currently no FDA-approved DL tools exist for abdominal or pelvic DSA. Future efforts should explore advanced generative AI and multimodal approaches.