The ONS Longitudinal Study – a prestigious past and a bright future

Northern Ireland has traditionally been well served with cross-sectional studies, including episodic surveys of poverty and social exclusion, and of health and social well-being. However, such studies are of limited use in either analysis of life-course transitions or in the separation of cause and effect, both important goals of current research strategies where renewed interest in equity and social exclusion is stimulating research into the effects of disadvantage on individuals over time. This is all the more urgent given the increased social and geographical mobility and greater fluidity in people’s lives. Such information can only be derived longitudinally, and there was a dearth of such large-scale general purpose studies in Northern Ireland. Information had not been included in the three British Birth Cohort studies of 1946, 1958 and 1970 and although other longitudinal studies, such as PRIME and Young Hearts, are available they were designed to answer research questions related to specific diseases. Although the British Household Panel Study has recently been extended to include Northern Ireland and there is now a Northern Ireland component to the Millennium Birth Cohort Study, neither is large enough to function as a general purpose longitudinal study to meet the general research or policy needs of Northern Ireland. In the early 2000s, a group of senior statisticians from the Northern Ireland Statistics and Research Agency (NISRA) and academics was convened to estimate the cost of a Northern Ireland Longitudinal Study (NILS), equivalent to others either already available in England and Wales or, at the time, in development in Scotland. The aim was to have a multi-cohort study that would fulfil a range of academic and policy-related purposes, with a sample size large enough to enable robust analysis of population sub-groups and of areas of policy relevance. Because the experience of the Scottish Longitudinal Study (SLS) team had shown that linkage to the 1991 census would incur considerable costs, especially if social class for earlier years had to be recoded to the NS-SEC classification used in the 2001 census, it was decided to start with the 2001 census. Funding for the establishment and maintenance of NILS (and its sister study NIMS, see below) was jointly secured in 2003 from the Department of Health, Social Services and Public Safety and the Research and Development Office of the then Health and Personal Social Services. All funding for the development and maintenance of NILS and NIMS now comes from the Health and Social Care Research and Development Division of the Public Health Agency (HSC R&D Division). NISRA helps to fund the NILS/ NIMS project both through the provision of accommodation to house all aspects of the NILS/NIMS operation and staff to maintain and develop the databases and provide strategic management of the project. Both NILS and NIMS were launched in December 2006.

The XXVII International Conference on Photonic, Electronic and Atomic Collisions was held at Queen's University Belfast, Northern Ireland, 27 July – 2 August 2011. Members of the Local Organising Committee were drawn from the School of Mathematics and Physics of Queen's University Belfast, the School of Physical Sciences at Dublin City University, the School of Physics at University College Dublin and the Department of Experimental Physics at the National University of Ireland, Maynooth.The Conference was attended by 566 participants with contributions from 54 countries. The meeting attracted 786 contributed papers for presentation in the poster sessions. The conference included 20 Special Reports selected from the contributed papers, and these are included in part 1 of this volume. During the meeting a total of 65 Progress Reports were also presented, and the authors invited to submit written versions of their talks (see Part 1). Of the total number of contributed papers, 663 are included as refereed abstracts in parts 2 to 15 of this volume of Journal of Physics: Conference Series.Part 1 of this volume includes detailed write-ups of the majority of plenary lectures, progress reports and special reports, constituting a comprehensive tangible record of the meeting, and is additionally published in hard-copy as the Conference Proceedings.There were 5 plenary lectures given by Margaret Murnane on Ultrafast processes in atomic dynamics; Chris Greene on Few-body highly-correlated dynamics; Michael Allan on Electron-molecule collisions; Yasunori Yamazaki on Antiproton and positron collisions and Thomas Stöhlker on Relativistic ion collisions. Ian Spielman, winner of the IUPAP Young Scientist Prize for 2011, gave a special lecture entitled Modifying interatomic interactions using Raman coupling: a tale of slowly colliding Bose-Einstein condensates. In addition an evening public lecture by Mike Baillie on How precise tree-ring dating raises issues concerning the frequency of extraterrestrial impacts drew an attentive and appreciative audience.The editors are indebted to Tara Spencer for her exceptional organisation skills and support in compiling this volume. Thanks are also due to Ian Stewart for his assistance with gathering and indexing the documents.We would also like to express our sincere appreciation to the ICPEAC sponsors for their financial support. I D Williams Queen's University Belfast H W van der Hart Queen's University Belfast J F McCann Queen's University Belfast D S F Crothers Queen's University Belfast EDITORS

Signalling by innate immune cells is critical to shaping the adaptive immune response to microbial infection. In this issue of The EMBO Journal, Labzin etal reveal that the adaptive immune system can instruct the innate response to adenovirus infection. In human macrophages, antibody-coated adenovirus triggers a novel TRIM21-dependent pathway that activates the NLRP3 inflammasome and the secretion of IL-1β.

Conference Article| August 01 1989 Kinetic studies of the inhibition of thrombin by synthetic peptide fragments of hirudin JANICE R. BAILIE; JANICE R. BAILIE 1Department of Biochemistry, Queen's University Belfast, Medical Biology Centre, 97 Lisburn Road, Belfast BT9 7BL Search for other works by this author on: This Site PubMed Google Scholar BRIAN WALKER BRIAN WALKER 1Department of Biochemistry, Queen's University Belfast, Medical Biology Centre, 97 Lisburn Road, Belfast BT9 7BL Search for other works by this author on: This Site PubMed Google Scholar Biochem Soc Trans (1989) 17 (4): 692–693. https://doi.org/10.1042/bst0170692 Article history Received: November 25 1988 Views Icon Views Article contents Figures & tables Video Audio Supplementary Data Peer Review Share Icon Share Facebook Twitter LinkedIn MailTo Cite Icon Cite Get Permissions Citation JANICE R. BAILIE, BRIAN WALKER; Kinetic studies of the inhibition of thrombin by synthetic peptide fragments of hirudin. Biochem Soc Trans 1 August 1989; 17 (4): 692–693. doi: https://doi.org/10.1042/bst0170692 Download citation file: Ris (Zotero) Reference Manager EasyBib Bookends Mendeley Papers EndNote RefWorks BibTex toolbar search Search Dropdown Menu toolbar search search input Search input auto suggest filter your search All ContentAll JournalsBiochemical Society Transactions Search Advanced Search Keywords: AMC, 7-amido-4-methyl coumarin This content is only available as a PDF. © 1989 Biochemical Society1989 Article PDF first page preview Close Modal You do not currently have access to this content.

Fortran programs for the time-dependent Gross–Pitaevskii equation in a fully anisotropic trap

BackgroundA socio-economic gradient in use of health care has been observed in a number of situations. These have been used to assess the performance of systems as well as frame...

Economic and Social History Society of Ireland Secretary's Report to the Annual General Meeting, Held at Queen's University Belfast – 30 November 2024

Aim. To examine socio-economic differences in mortality of South Asian and West Indian migrants. Design. ONS Longitudinal Study, a 1% sample of the population of England and Wales. Participants. First generation South Asian and West Indian migrants present at the 1971 and 1981 censuses, aged under 65 years in 1981, were classified by occupational class, access to cars, housing, and a deprivation score. Outcome measures. Relative risks of mortality, 1981-1997. Results. There was considerable upward social mobility but most people remained socially stable, mainly relatively disadvantaged compared to all other study members. High levels of owner occupied housing among South Asians at both censuses were an exception. Socio-economic differentials in mortality were significant with car access in 1981 (relative risk 1.32, 95% confidence interval 1.03-1.70), and housing (rented vs owner occupied relative risk 1.50, 95% confidence interval 1.08-2.08) among South Asians and, among West Indians with car access in 1981 (relative risk 1.43, 95% confidence interval 1.05-1.94). Mortality was not significantly associated with socioeconomic circumstances in 1971. Conclusion. The disparity between those who remained advantaged or who moved up, and those who remained persistently disadvantaged, would have been a factor underlying the stronger differentials by later socio-economic circumstances. As these migrants age an increase in health inequalities could be expected.

This article explores the exact nature of a state's due diligence obligation since the 11 September 2001 terrorist attacks. It addresses aspects of a state's due diligence obligation in reasonably protecting the international rights of states and of non-state actors generally and examines the interplay of this legal obligation with international non-state terror organisations. The exact nature of the due diligence obligation that has emerged since 11 September demands ongoing and substantial 'Hugo Grotius, De jure belli ac pacis libri tres (3 vols, Amsterdam, 1646; James Brown Scott (ed.), Francis W. Kelsey (trans.), Oxford and London, 1925), vol. II, chapter XXI, §11, paragraphs 1-2, 523. See Jan Arno Hessbruegge, 'The historical development of the doctrines of attribution and due diligence in international law', New York University Journal of International Law and Policy 36 (2-3) (2004), 265-306: 283-4. Hessbruegge credits Grotius with laying the framework for the modern due diligence principle. *The author would like to acknowledge the generous financial support of the Overseas Research Students Awards Scheme and Queen's University Belfast for his current research. While accepting full responsibility for any errors, he would like to thank the following for their valuable assistance in preparing this article: Prof. Phil Scraton and Dr Jean Allain of Queen's University Belfast; Prof. Mr P.A. Nollkaemper, Mr Dr H.G. van der Wilt and Mr J.P.J. van Wielink of the University of Amsterdam; Dr A.J.J. de Hoogh of the University of Groningen; and Dhr. Prof. Dr K.C. Wellens of Radboud University Nijmegen. Thanks also to Dr John Doyle, the reviewers for Irish Studies in International Affairs and Helena King and Fionnuala Dillane of the Royal Irish Academy's Publications Office for editorial assistance. An earlier version of this article was presented at the Royal Irish Academy's Graduate Research Seminar on 25 November 2004. Author's e-mail: rbarnidge01 @qub.ac.uk Irish Studies in International Affairs, Vol. 16 (2005), 103-125. This content downloaded from 157.55.39.159 on Fri, 09 Dec 2016 05:24:13 UTC All use subject to http://about.jstor.org/terms 104 Irish Studies in International Affairs counter-terrorism efforts by states, and this need seems to be recognised by state practice. This article poses some questions and makes some observations regarding, among other issues, the implications of an international non-state terrorist organisation's attack abroad when the state on whose territory the organisation operates is unable, while acting with due diligence, to control the organisation.

BJOG: An International Journal of Obstetrics & GynaecologyVolume 76, Issue 3 p. 200-207 CLINICAL SIGNIFICANCE OF THE AMNIOTIC FLUID OESTRIOL LEVEL* Fatma A. Aleem, Fatma A. Aleem Research Assistant Department of Gynaecology, Queen's University of Belfast, and Biochemistry Laboratory, Royal Victoria Hospital, BelfastSearch for more papers by this authorJ. H. M. Pinkerton, J. H. M. Pinkerton Professor Department of Gynaecology, Queen's University of Belfast, and Biochemistry Laboratory, Royal Victoria Hospital, BelfastSearch for more papers by this authorD. W. Neill, D. W. Neill Senior Biochemist Department of Gynaecology, Queen's University of Belfast, and Biochemistry Laboratory, Royal Victoria Hospital, BelfastSearch for more papers by this author Fatma A. Aleem, Fatma A. Aleem Research Assistant Department of Gynaecology, Queen's University of Belfast, and Biochemistry Laboratory, Royal Victoria Hospital, BelfastSearch for more papers by this authorJ. H. M. Pinkerton, J. H. M. Pinkerton Professor Department of Gynaecology, Queen's University of Belfast, and Biochemistry Laboratory, Royal Victoria Hospital, BelfastSearch for more papers by this authorD. W. Neill, D. W. Neill Senior Biochemist Department of Gynaecology, Queen's University of Belfast, and Biochemistry Laboratory, Royal Victoria Hospital, BelfastSearch for more papers by this author First published: March 1969 https://doi.org/10.1111/j.1471-0528.1969.tb05822.xCitations: 27 * This paper incorporates work from a Thesis for which the Ph.D.(Belfast) was granted to F.A.A. AboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onFacebookTwitterLinked InRedditWechat Citing Literature Volume76, Issue3March 1969Pages 200-207 RelatedInformation

The concepts of unobserved frailty and selection have been extensively analyzed with respect to phenomena like mortality deceleration at old ages and mortality convergence or cross overs between populations (for example American black and white populations, men and women). Despite the long-time observation of converging mortality risks in differential socioeconomic mortality research, the interest in the connection between frailty, selection, and health and mortality inequalities over a life course approach has increased only recently. This overview of the literature summarizes the main concepts of unobserved frailty and socioeconomic differences in mortality and how frailty and selection relate to these differences at old ages. It then reviews the evidence coming from the existing studies. Although the number of studies is still limited, the body of research on unobserved frailty and socioeconomic inequalities in health and mortality in a life course approach is growing. The results, however, are contradictory, and whether selection plays a major role in shaping the observed socioeconomic mortality patterns at old ages is still controversial.

An examination of English verse translations of Beowulf, including Seamus Heaney's version alongside other influential renditions. A senior scholar writing here at the height of his powers and bringing experience and insight to an important topic... the second chapter is one of the best short, general introductions to the artistry of the poem I have read...A dizzying and engaging narrative. Dr Chris Jones, Senior Lecturer in English Poetry, Department of English, University of St Andrews Translations of the Old English poem Beowulf proliferate, and their number continues to grow. Focusing on the particularly rich period since 1950, this book presents a critical account of translations in English verse, setting them in the contexts both of the larger story of the recovery and reception of the poem and of perceptions of it over the past two hundred years, and of key issues in translation theory. Attention is also paid to prose translation and to the creative adaptations of the poem that have been produced in a variety of media, not least film. The author looks in particular at four translations of arguably the most literary and historical importance: those by Edwin Morgan [1952], Burton Raffel [1963], Michael Alexander [1973] and SeamusHeaney [1999]. But, from an earlier period, he also gives a full account of William Morris's strange 1898 version. Hugh Magennis is Professor of Old English Literature at Queen's University Belfast.

Graham Gibson, previously a third-year student nurse at Queen's University Belfast, discusses the experience of his final placement in an emergency department.

The Terawatt Apparatus for Relativistic And Non-linear Interdisciplinary Science (TARANIS), installed in the Centre for Plasma Physics at the Queen's University Belfast, supports a wide ranging science program, including laser-driven particle acceleration, X-ray lasers and high energy density physics experiments. We present (1) an overview of the laser facility, (2) results of preliminary investigations on proton acceleration, laser action at 13.9 nm and Kα sources and (3) speculation on future experiments using these extreme sources.

Taking inspiration from a Frank Gehry sketch, Belgian architect Riet Eeckhout, through her process of ‘drawing out’, has produced a series of abstract works of considerable scale. Michael McGarry, Professor of Architecture at Queen's University Belfast, links her practice to the psycho‐geography of the Belgian landscape and the internal geometries of her house and street in Flanders.