Time series quantum classifiers with amplitude embedding

Recent advances in quantum computing and machine learning have brought about a promising intersection of these two fields, leading to the emergence of quantum machine learning (QML). However, the integration of quantum computing and machine learning poses several challenges. One of the prominent challenges lies in the presence of barren plateaus (BP) in QML algorithms, particularly in quantum neural networks (QNNs). Recent studies have successfully identified the fundamental causes underlying the existence of BP in QNNs. This paper presents a framework designed to explore the interplay of multiple factors contributing to the BP problem in quantum neural networks (QNNs), which poses a critical challenge for the practical applications of QML. We focus on the combined influence of data encoding, qubit entanglement, and ansatz expressibility in hybrid quantum neural networks (HQNNs) for multi-class classification tasks. Our framework aims to empirically analyze the joint impact of these factors on the training landscape of HQNNs. Our results show that the occurrence of the BP problem in HQNNs is contingent upon the expressibility of the underlying ansatz and the type of the adopted data encoding technique. Additionally, we observe that qubit entanglement also plays a role in exacerbating the BP problem. Leveraging various evaluation metrics for classification tasks, we systematically evaluate the performance of HQNNs and provide recommendations tailored to different constraint scenarios. Our findings emphasize the significance of our framework in addressing the practical success of QNNs.

Medical decision-making is increasingly integrating quantum computing (QC) and machine learning (ML) to analyze complex datasets, improve diagnostics, and enable personalized treatments. While QC holds the potential to accelerate optimization, drug discovery, and genomic analysis as hardware capabilities advance, current implementations remain limited compared to classical computing in many practical applications. Meanwhile, ML has already demonstrated significant success in medical imaging, predictive modeling, and decision support. Their convergence, particularly through quantum machine learning (QML), presents opportunities for future advancements in processing high-dimensional healthcare data and improving clinical outcomes. This review examines the foundational concepts, key applications, and challenges of these technologies in healthcare, explores their potential synergy in solving clinical problems, and outlines future directions for quantum-enhanced ML in medical decision-making.

Clustering bike sharing stations using Quantum Machine Learning: A case study of Toronto, Canada

In this work, we studied the use of Quantum Machine Learning (QML) algorithms for binary classification and compared their performance with classical Machine Learning (ML) methods. QML merges principles of Quantum Computing (QC) and ML, offering improved efficiency and potential quantum advantage in data-driven tasks and when solving complex problems. In binary classification, where the goal is to assign data to one of two categories, QML uses quantum algorithms to process large datasets efficiently. Quantum algorithms like Quantum Support Vector Machines (QSVM) and Quantum Neural Networks (QNN) exploit quantum parallelism and entanglement to enhance performance over classical methods. This study focuses on two common QML algorithms, Quantum Support Vector Classifier (QSVC) and QNN. We used the Qiskit software and conducted the experiments with three different datasets. Data preprocessing included dimensionality reduction using Principal Component Analysis (PCA) and standardization using scalers. The results showed that quantum algorithms demonstrated competitive performance against their classical counterparts in terms of accuracy, while QSVC performed better than QNN. These findings suggest that QML holds potential for improving computational efficiency in binary classification tasks. This opens the way for more efficient and scalable solutions in complex classification challenges and shows the complementary role of quantum computing.

Abstract: This book presents a comprehensive exploration of quantum cryptography as an emergent paradigm in secure communications, enhanced through the integration of quantum computing and machine learning methodologies. Grounded in the principles of quantum mechanics—superposition, entanglement, and the no-cloning theorem—it develops a conceptual and mathematical framework for information-theoretic security resistant to both classical and quantum adversaries. The work identifies the limitations of classical cryptographic systems in the advent of large-scale quantum computation and proposes hybrid architectures that leverage machine learning for adaptive threat detection, protocol optimization, and anomaly classification in quantum key distribution (QKD) environments. Methodologically, the text synthesizes theoretical analysis, formal security proofs, and empirical evaluation using both quantum simulation platforms and experimental testbeds. Key results demonstrate that quantum–machine learning synergies can improve key generation rates, enhance noise tolerance, and accelerate real-time countermeasure deployment. The implications extend to the design of scalable, interoperable cryptographic systems compatible with emerging quantum internet infrastructures, while also addressing ethical and regulatory considerations in deployment. By combining rigorous academic analysis with practical implementation insights, this book establishes a scholarly and applied foundation for next-generation secure communication systems in the quantum era. Keywords Quantum cryptography, quantum key distribution, quantum computing, machine learning, quantum machine learning, cryptographic security, post-quantum cryptography, hybrid architectures, adaptive protocol optimization, information-theoretic security, secure communications, quantum internet, ethical implications in cryptography

In the realm of artificial intelligence (AI), the integration of quantum computing with machine learning (ML) has sparked a significant shift in how we approach problems that were once deemed computationally infeasible. Quantum Machine Learning (QML) represents an exciting intersection of quantum mechanics and machine learning, potentially revolutionizing areas such as optimization, pattern recognition, and data analysis. Although quantum computing itself is still in its infancy, the synergy between quantum theory and classical machine learning algorithms promises to unlock new capabilities that classical computing could never achieve. This paper delves into the latest advancements in Quantum Machine Learning, its theoretical underpinnings, practical applications, and the challenges that researchers face as they explore this rapidly growing field.

Quantum Machine Learning (QML) is emerging as a transformative technology in cybersecurity, particularly in anomaly detection for cyber security audits. Traditional machine learning models are effective but face scalability and efficiency limitations as cyber threats grow more sophisticated. QML, leveraging quantum computing’s ability to process and analyze large datasets in parallel, offers potential breakthroughs in identifying anomalous patterns that could signify cyber threats such as data breaches, insider threats, or unauthorized access. Content Analysis Research Methodology used in this research work. This paper explores the integration of QML into anomaly detection systems for cyber security audits, where detecting deviations from normal behavior is crucial. Quantum algorithms, particularly those based on Quantum Support Vector Machines (QSVM), Quantum Neural Networks (QNN), and Quantum Principal Component Analysis (QPCA) can enhance the detection of subtle anomalies that classical algorithms may overlook due to noise or the complex, high-dimensional nature of cyber data. The inherent properties of quantum computing, such as superposition and entanglement, allow for more efficient feature selection and optimization, potentially leading to faster and more accurate anomaly detection. The impact of implementing QML in cyber security audits is profound. First, it enhances detection capabilities by identifying anomalies with greater precision, reducing false positives, and improving response times to cyber incidents. Second, quantum algorithms’ ability to manage exponentially large datasets makes them ideal for environments with extensive data logs, such as enterprise networks and cloud infrastructures. Third, as cyber threats become increasingly adaptive and stealthy, QML offers a dynamic solution that evolves alongside these threats by continuously learning from new patterns of attack. However, practical challenges remain, including the need for quantum hardware advancements, the development of hybrid quantum-classical models, and ensuring the interpretability of quantum models in audit scenarios. Despite these challenges, early research and experimental implementations demonstrate the potential of QML to revolutionize anomaly detection in cybersecurity audits. This paper concludes that while QML is still in its early stages, its application to anomaly detection holds promise for significantly enhancing the effectiveness of cyber security audits. The impact of this technology, when fully realized, could redefine how organizations protect their networks and data from ever-evolving cyber threats, making QML a critical area for future research and development in cybersecurity.

Malware Detection and Analysis play a primary role in information access points such as workstations, servers, cloud storage, and mobile devices. Securing information from malware is a challenging task, and existing anti-malware applications suffer from detecting new types of attacks. In recent years, machine learning-based malware detection techniques have been applied for effective malware detection and analysis for existing and new types of malware with few drawbacks such as misclassification and increased complexity. To overcome this, the chapter focuses on adopting deep learning (DL) models to build an anti-malware application via modern Artificial Intelligence (AI) techniques. Quantum Machine Learning (QML) is a research area that explores the interplay of ideas from quantum computing and machine learning. The proposed framework is built with various DeepNet Models to improve predicted accuracy, which can carry out universal quantum computations. QML performs the information processing with quantum computers relies on substantially different laws of physics called quantum theory. Initially, executable files will be converted to binary files and forwarded to DeepNet Models to multi-classify the novel variants of malware. A comprehensive survey is carried out on the implementation of ML/DL models for malware detection and analysis by considering various factors.

Quantum machine learning (QML) has emerged as a promising domain to leverage the computational capabilities of quantum systems to solve complex classification tasks. In this work, we present the first comprehensive QML study by benchmarking the MedMNIST-a diverse collection of medical imaging datasets on a 127-qubit real IBM quantum hardware, to evaluate the feasibility and performance of quantum models (without any classical neural networks) in practical applications. This study explores recent advancements in quantum computing such as device-aware quantum circuits, error suppression, and mitigation for medical image classification. The proposed methodology is comprised of three stages: preprocessing, generation of noise-resilient and hardware-efficient quantum circuits, optimizing/training of quantum circuits on classical hardware, and inference on real IBM quantum hardware. Firstly, we process all input images in the preprocessing stage to reduce the spatial dimension due to quantum hardware limitations. We generate hardware-efficient quantum circuits using backend properties expressible to learn complex patterns for medical image classification. After classical optimization of QML models, we perform inference on real quantum hardware. We also incorporate advanced error suppression and mitigation techniques in our QML workflow, including dynamical decoupling (DD), gate twirling (Twir), and matrix-free measurement mitigation (M3) to mitigate the effects of noise and improve classification performance. The experimental results showcase the potential of quantum computing for medical imaging and establish a benchmark for future advancements in QML applied to healthcare.

Quantum Machine Learning (QML) is an emerging interdisciplinary field that integrates quantum computing with classical machine learning techniques to enhance computational efficiency and solve complex problems beyond the capabilities of classical systems. This paper explores fundamental QML algorithms, including quantum-enhanced data processing, quantum neural networks, and quantum support vector machines. We discuss how quantum speedup can be achieved through quantum parallelism and entanglement, leading to improvements in optimization and data classification tasks. Additionally, we highlight applications of QML in areas such as drug discovery, financial modeling, and cryptography. While current quantum hardware imposes limitations, ongoing advancements in quantum algorithms and error correction techniques suggest a promising future for QML. We conclude with a discussion on the challenges and future directions in the field, emphasizing the need for hybrid quantum-classical approaches and scalable quantum hardware.

Quantum Machine Learning (QML) is a new phraseology in the world today. With various upcoming Artificial Intelligence (AI) technologies, everyday data scientists and corporate around the world are trying to harness its power. QML borrows concepts of Quantum Computing and QML algorithms enhance the existing Machine Learning (ML) algorithms by processing datasets more efficiently. Quantum Computers are a powering force driving QML algorithms that boosts computational power and helps analyse data. QML algorithms can be applied in sectors involving number crunching, pattern identification and so on. In the existing world, QML can be a game-changer for organizations that work on identifying product correlations and customer behaviour in a brief time. This paper discusses studies related to principles of Quantum Mechanics, Quantum Computing and QML algorithm. Additionally, it explores opportunities and challenges faced in the field of QML. Lastly, the paper talks about QML applications and compares various available QML toolkits from the market. Future direction and exhaustive survey of papers from various spectrums related to Quantum Computing is presented in this paper.

Quantum Machine Learning (QML) is an emerging field at the intersection of quantum computing and machine learning, aiming to enhance classical machine learning methods by leveraging quantum mechanics principles such as entanglement and superposition. However, skepticism persists regarding the practical advantages of QML, mainly due to the current limitations of noisy intermediate-scale quantum (NISQ) devices. This study addresses these concerns by extensively assessing Quantum Neural Networks (QNNs)-quantum-inspired counterparts of Artificial Neural Networks (ANNs), demonstrating their effectiveness compared to classical methods. We systematically construct and evaluate twelve distinct QNN configurations, utilizing two unique quantum feature maps combined with six different entanglement strategies for ansatz design. Experiments conducted on a wind energy dataset reveal that QNNs employing the $\mathbf{Z}$ feature map achieve up to $93 \%$ prediction accuracy when forecasting wind power output using only four input parameters. Our findings show that QNNs outperform classical methods in predictive tasks, underscoring the potential of QML in real-world applications.

The rapid evolution of cyber threats has rendered conventional security approaches inadequate for managing increasingly sophisticated risks. This study introduces a Quantum Machine Learning Cybersecurity Framework that leverages quantum computing and machine learning to enhance cybersecurity across multiple dimensions. The research employs a structured methodology, beginning with the integration of Quantum Key Distribution (QKD) for secure key exchange and progressing through the deployment of Quantum Neural Networks (QNN) and Quantum Support Vector Machines (QSVM) for anomaly detection and adversarial threat management. The framework also incorporates Quantum Reinforcement Learning (QRL) for autonomous incident response, a Quantum Authentication module for securing identity verification using biometric and behavioral data, and a Policy Compliance Interface powered by Quantum Compliance Analyzers for regulatory adherence. Experimental results demonstrated substantial improvements in cybersecurity metrics, including a 96% accuracy in threat detection, a 28% reduction in incident response time, and a 96% success rate in compliance simulations. These findings underscore the framework's capacity to offer adaptive, scalable, and efficient cybersecurity solutions tailored to modern challenges. This study provides a significant step toward integrating quantum technologies into practical cybersecurity applications, paving the way for future innovations in intelligent, secure, and adaptable defense systems.

The ability to accurately classify disease subtypes is of vital importance, especially in oncology where this capability could have a life saving impact. Here we report a classification between two subtypes of non-small cell lung cancer, namely Adenocarcinoma versus Squamous cell carcinoma. The data consists of approximately 20,000 gene expression values for each of 104 patients. The data was curated from Kuner (Geo lung cancer data set—gse10245, 2009, http://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE10245 ) and Golumbic (Geo lung cancer data set—gse18842, 2010, http://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE18842 ). We used a combination of classical and quantum machine learning models to successfully classify these patients. We utilized feature selection methods based on univariate statistics in addition to XGBoost (Guestrin and Chen in Xgboost: a scalable tree boosting system, 2007, https://dl.acm.org/citation.cfm?id=1273596 ). A novel and proprietary data representation method developed by one of the authors called QCrush was also used as it was designed to incorporate a maximal amount of information under the size constraints of the D-Wave quantum annealing computer. The machine learning was performed by a quantum Boltzmann machine. This paper will report our results, the various classical methods, and the quantum machine learning approach we utilized.

As the limits of classical machine learning (ML) become increasingly evident—especially in terms of computational scalability and data processing—quantum computing emerges as a promising frontier capable of addressing these challenges. Quantum Machine Learning (QML) represents the intersection of quantum computing and traditional ML, aiming to leverage quantum phenomena such as superposition, entanglement, and quantum parallelism to enhance learning capabilities, accelerate training, and solve complex problems that are intractable for classical algorithms. This paper provides a comprehensive overview of the evolving field of QML, beginning with the theoretical foundations of quantum computing and its synergy with classical machine learning principles. We explore key QML algorithms, including quantum support vector machines (QSVM), variational quantum classifiers (VQC), quantum neural networks (QNN), and hybrid quantum-classical approaches that exemplify the practical integration of both paradigms. We further examine real-world applications of QML across domains such as drug discovery, finance, climate modeling, and optimization, where quantum enhancements have begun to show early but promising results. Despite its theoretical potential, QML faces substantial limitations, including quantum hardware instability, limited qubit scalability, noise sensitivity, and unresolved challenges in quantum data encoding and interpretability. In synthesizing recent advancements and persistent obstacles, this paper highlights the importance of continued interdisciplinary research, algorithmic refinement, and hardware evolution. We also outline future directions that could lead QML from experimental promise to practical utility, including developments in quantum error correction, benchmarking standards, and application-specific quantum architectures