Abstract With the help of dental implants, an oral rehabilitation can be performed not only very complex, but also very complete of various types of edentulous spaces. After insertion of the dental implants, they can be subsequently prosthetically restored through a wide range of implant-supported prosthetic restorations. In this material, we tried to highlight some particular aspects from the point of view of the laboratory stages of dental technique, which intervene in the technological flow of making implant-supported prosthetic restorations from ceramic masses on Zirconia structure.

Abstract Acquired thrombotic thrombocytopenic purpura (TTP) is a rare thrombotic microangiopathy, affecting preferentially young women in their fourth decade. Intensive care admission is often required due to organ dysfunction development risk and for specific critical care measures (Plasma Exchange-PEX). In this article, we will discuss our experience with PEX in the treatment of TTP. Case report: A previously healthy 13-year-old female presented with neurological impairment, and suspicion of stroke. The head computed tomography (CT) scan revealed absence of acute intracranian pathology, and biological evaluation displayed severe thrombocytopenia and haemolytic anemia. After 24 hours, the neurological symptoms were remitted and suspicion of thrombotic thrombocytopenic purpura was raised. The presence of ADAMTS-13 antibodies and Moschcowitz’s pentad confirmed the diagnosis. Discussions: The distinctiveness of this case lies in the development of the disease in a 13-year-old person, though TTP usually occurs after the age of 40. The exact cause of ADAMTS-13 low activity could not be established. The use of a high dose of steroids and of plasma exchange is considered to be the first line therapy, with the use of monoclonal antibodies in refractory cases, as it was in our case. Conclusions: The primary end points of our management was to prevent organ damage and to achieve a platelet count greater than 150 000 /µL, as well as a normal or an almost normal lactate dehydrogenase. We achieved this by using high dose corticosteroid therapy, filtration of approximately 50 liters of plasma in 14 PEX session and by administration of monoclonal antibodies.

Abstract This study aims to determine the job satisfaction level of midwives, and the factors that have an effect on those levels. This cross-sectional analytic study was carried out in a total of 21 health institutions including 17 primary health care and 4 secondary health care institutions in a city center. 428 midwives were included in the study. To determine the job satisfaction of midwives, the Minnesota Satisfaction Questionnaire (MSQ) was used. According to the scores obtained from MSQ, quartiles in ¼ were created. In statistical analysis, the difference between the mean scores among groups was analysed with independent samples t-test. P values less than 0.05 were considered significant. The results demonstrated that the majority of midwives had a moderate level of job satisfaction.

Abstract Procalcitonin is a new generation marker used to differentiate bacterial from viral pneumonia. Although it is not a test routinely used in practice, it can be included in diagnosis and treatment algorithm of pneumonia in children. Studies have shown the effectiveness of procalcitonin in determining of duration of antibiotherapy and hospitalization, too. The test is superior to the other laboratory parameters, compared to reactive C protein, inclusively. Depending on the result of the pulmonary x-ray (bacterial pneumonia) admitted patients were included in: study group – patients with increased values of procalcitonin, and control group – patients with normal values ones. The study proposed a comparative analysis; the correlation index was used to demonstrate how laboratory parameters can interact, and the evolutionary trend of studied parameters was analysed. The results are consistent with the literature data, validating the superiority of procalcitonin in establishing the etiologic diagnosis and the treatment evaluation in bacterial pneumonia in children.

Abstract Sedentary behavior, both professional, occupational, leisure and recreational, is one of the major risk factors for cardio-metabolic health and premature mortality. But, this type of sedentary behavior can be found in many of the existing professional activities in 2021, among them being the professional activities with a medical profile in the field of dentistry: specific activities in the dentist’s office (and here we discuss about dentists and dental nurses) and activities specific in the dental laboratory (in this case, we are talking about dental technicians).

Abstract Breast cancer is the most common cancer in women and a major public health problem, affecting 2.1 million women each year globally and causing the highest number of cancer-related deaths among women. In 2018, an estimated 627,000 women died from breast cancer (about 15% of all cancer deaths among women). To improve survival, early detection is essential. There are two strategies for early detection of breast cancer: early diagnosis and screening.(1) In Romania, the latest statistics show a higher incidence of breast cancer compared to the European average of 7929 new cases / year with a mortality of 3101 deaths / year.(2)

Abstract Considering actual SARS-COV 2 pandemic, the comfort and time of the female patient’ trend is to minimize the time spent in the doctor’s office, so that auto-testing is a solving problem in this context. This paper aims at the importance of self-collected urine and vaginal samples, since actual studies are showing that is a complementary method in HPV-testing and a screening method for prevention of cervical cancer. Genital HPV infection is responsible for approximately 99% of cervical cancers, and is considered a sexually transmitted disease. Given that eight out of ten patients have at least one episode of HPV infection in their lifetime, there is a need for a method of early detection of genital HPV infection. Cervical cancer is the second type of diagnosed cancer in the rank of genital cancers and the third leading cause of cancer death among the female population. In Romania, the frequency of cervical cancer and mortality caused by this type of cancer remains high. In 2018 Globocan, it was mentioned that the occurrence of cervical cancer in Romania was 8.6%, and the mortality was 19.5/10,000 women. Worldwide, the following have been implemented: primary prevention programmes (via immunization) and secondary prevention programmes – traditional cytological testing, to which co-tests have been added. In the co-testing sector, there has been found with an updated visa – the self-harvesting test, being considered a complementary and innovative method in genital HPV testing, which aims to: identify the presence of highly oncogenic HPV strains with a marked sensitivity. Self-harvesting testing aims to: signal the presence of highly oncogenic strains, extrapolation can lead to early identification of the number of cases of precancerous lesions of the cervix and implicitly of cervical cancer.

Abstract Numerous studies in the last decades report a frequent association of marginal periodontal disease with some systemic metabolic disorders, such as diabetes or obesity. The prevalence of these diseases is growing alarmingly both globally and in our country. Recent data from the literature confirm that advanced forms of periodontal disease can influence the evolution of type 2 diabetes. This may provide a premise for better glycemic control.

Abstract Atopic dermatitis (AD) is a chronic inflammatory disease characterized by skin dryness, pruritus and eczematous lesions with various periods of relapse. Symptomatology can appear in childhood and can persist in adulthood. Chronic treatment is required with corticosteroids being the standard options. The side effects of this type of long-term treatment represent a major concern for the pediatric patients. This review aims to give an update of the options used for treatment, apart from the systemic corticosteroids. Mild-to-moderate AD had a good response to creams containing fig and oatmeal extracts and inhibitors of phosphodiesterase-4 (crisaborole). In cases of severe AD, future treatment options could include monoclonal antibodies such as omalizumab and dupilumab

Abstract Nowadays, at work, many people spend more than half of their entire day working in a sitting position. Maintaining this position for a long period of time is a risk factor for health. The results of various studies have shown associations between maintaining a prolonged sitting position with morbidity due to chronic diseases, such as cardiovascular disease, diabetes, metabolic syndrome, obesity, etc. And, as we have already mentioned in the first part of this study, dental technicians are part of this category of staff, who carry out most of their specific activity, in a sitting position.