All Research Papers Published In Cancer Genetics

Research Article
10.1016/j.cancergen.2025.10.026

22. Accurate and reliable detection of clonal hematopoiesis in plasma cell-free DNA

Dec 01, 2025
Cancer Genetics
Alyssa Parker + 5 more +5

Research Article
10.1016/j.cancergen.2025.10.027

23. Prediction of BRAF V600 mutation status in cutaneous melanoma using an explainable deep learning model

Dec 01, 2025
Cancer Genetics
Vibha Rao + 2 more +2

Research Article
10.1016/j.cancergen.2025.10.094

90. Assessment of conflicts in hereditary cancer genetic test interpretations between ClinGen and US clinical laboratories

Dec 01, 2025
Cancer Genetics
Elizabeth Yang + 2 more +2

Research Article
10.1016/j.cancergen.2025.10.091

87. Cryptic MLLT10 insertion into KMT2A detected by RNA fusion panel and optical genome mapping

Dec 01, 2025
Cancer Genetics
Qing Wei + 6 more +6

Research Article
10.1016/j.cancergen.2025.10.029

25. Improving fusion detection sensitivity in the TruSight Oncology 500 Panel through DNA-based structural variant analysis

Dec 01, 2025
Cancer Genetics
Qiliang Ding + 1 more +1

Research Article
10.1016/j.cancergen.2025.10.101

YME1L facilitates the development of non-small cell lung cancer by promoting activation of mitochondria-Gαi1-Akt pathway.

Nov 01, 2025
Cancer genetics
Mindan Wu + 6 more +6

Research Article
10.1016/j.cancergen.2025.10.105

LncRNA SNHG29 Suppresses Epithelial Ovarian Cancer Cell Invasion and Migration via miR-20b-3p/GNAI3 Axis Regulation.

Nov 01, 2025
Cancer genetics
Chencheng Dai + 9 more +9

Research Article
2
10.1016/j.cancergen.2025.11.007

WDR54 enhances NF-κB signaling to promote progression of hepatocellular carcinoma.

Nov 01, 2025
Cancer genetics
Hengyong Zhai + 4 more +4

Hepatocellular carcinoma (HCC) is a major health threat worldwide. This study found that WDR54 is overexpressed in liver cancer tissues and is inversely correlated with patient prognosis. Through comprehensive cell biology experiments, we demonstrated that WDR54 plays a pivotal role in promoting the malignant proliferation and metastasis of HCC. Further molecular biology investigations, including transcriptome sequencing, revealed that WDR54 exerts its biological effects by modulating the NF-κB signaling pathway. Specifically, WDR54 interacts with RBBP5 to enhance the transcription of p65, thereby promoting HCC proliferation and metastasis. Additionally, the potential impact of WDR54 on tumor cell metabolism and tumor heterogeneity is explored. The findings of this study deepen our understanding of the molecular pathology of liver cancer and lay a foundation for future clinical applications.

Research Article
10.1016/s2210-7762(25)00248-0

Editorial Board

Nov 01, 2025
Cancer Genetics

Research Article
10.1016/j.cancergen.2025.11.003

Villin1 predicts survival and adjuvant TACE response in hepatocellular carcinoma.

Nov 01, 2025
Cancer genetics
Dongjun Luo + 3 more +3