High Density Polyethylene (HDPE) plastic waste, particularly from plastic bags, poses serious environmental challenges due to its non-biodegradable nature. This study evaluates HDPE as a partial fine aggregate replacement in concrete, focusing on t

The domestic construction industry in New Zealand has long been challenged by persistent material shortages and elevated construction costs. In contrast, prefabricated steel structure buildings from China—backed by substantial technological accum

The integration of artificial intelligence (AI) into QbD frameworks has further revolutionized this process, enabling enhanced efficiency, precision, and innovation in formulation development. This review explores the role of AI in advancing QbD for pharmaceutical formulations, highlighting its applications, benefits, challenges, and future potential. By analyzing recent advancements, Our goal is to present a thorough grasp of how AI-driven QbD is influencing medication development going forward. Quality by Design (QbD) frameworks that incorporate artificial intelligence (AI) offer a revolutionary method for developing pharmaceutical formulations..This review explores how AI-driven tools enhance the QbD process by optimizing formulation design, predicting critical quality attributes (CQAs), and streamlining risk assessment. By utilizing machine learning models, AI enables accurate determination of essential material characteristics (EMCs) and vital process parameters (VPPs), reducing experimental trial-and-error. The abstract highlights case studies where AI has improved formulation stability, bioavailability, and manufacturing efficiency. Furthermore, it discusses the potential of AI to integrate real-time data analytics for continuous process verification, ensuring robust quality control. The authors emphasize that AI-augmented QbD accelerates development timelines.

Good health encompasses not only physical well-being but also mental wellness. Achieving and maintaining good health often necessitates a financial investment in essential health services. For economically disadvantaged segments of society, health-related expenditures can deplete savings and potentially thrust individuals into poverty. Health insurance offers financial protection when accessing healthcare services. This study aims to analyse health insurance coverage in India over the past two decades using secondary data from NFHS 3, NFHS 4 and NFHS 5. The findings indicate a significant increase in enrollment in health insurance; however, it is noteworthy that the majority of those covered are beneficiaries of the Employees' State Insurance Scheme (ESIS) or government-funded health insurance programs. Higher enrollment rates are observed in rural areas, primarily due to these government-sponsored health insurance initiatives. Most states exhibited an increase in beneficiaries, with Rajasthan, Andhra Pradesh, and Chhattisgarh emerging as the top-performing states. However, there is considerable variation among states; many states, such as Bihar and Uttar Pradesh, have among the lowest coverage rates. Chhattisgarh stands out for having one of the highest coverage levels, largely attributed to the government-funded health insurance schemes (RSBY and the State Health Insurance Scheme), which have led to increased coverage in rural areas.

Infrastructure development in Indonesia is increasing continuously, requiring efficient project management to address cost, time, and quality challenges. Therefore, this study aimed to examine the basement construction at Gatot Subroto BRI Tower

Mandibular reconstruction after tumor resection requires stable fixation that restores function and facial symmetry while minimizing invasiveness. This study presents and validates a bicortical screw–plate Temporary External Fixator (TEF) desig

This study aims to map Critical Success Factors (CSFs) in the implementation of open innovation (OI) in the Indonesian manufacturing industry. The initial identification of critical factors was conducted through a review of relevant literature,

The global increase in the elderly population, which is expected to reach 2.1 billion by 2050, has highlighted the need for reliable monitoring systems to assist elderly individuals, especially those with dementia. More than 55 million people world

Nitrogen oxides (NOx) are major air pollutants that contribute to environ mental and health issues. The photocatalytic issues. The photocatalytic reduction of NOx into ammonia (NH3) offers a sustainable approach to mitigating emissions whi

This study aims to develop and validate the MuSyRI early-warning index for critical e-government infrastructure. This study introduces the Multi-Domain Synergistic Resilience Index (MuSyRI), a bounded [0–1] metric that identifies nonlinear, compou